In recent years,autonomous driving technology has made good progress,but the noncooperative intelligence of vehicle for autonomous driving still has many technical bottlenecks when facing urban road autonomous driving...In recent years,autonomous driving technology has made good progress,but the noncooperative intelligence of vehicle for autonomous driving still has many technical bottlenecks when facing urban road autonomous driving challenges.V2I(Vehicle-to-Infrastructure)communication is a potential solution to enable cooperative intelligence of vehicles and roads.In this paper,the RGB-PVRCNN,an environment perception framework,is proposed to improve the environmental awareness of autonomous vehicles at intersections by leveraging V2I communication technology.This framework integrates vision feature based on PVRCNN.The normal distributions transform(NDT)point cloud registration algorithm is deployed both on onboard and roadside to obtain the position of the autonomous vehicles and to build the local map objects detected by roadside multi-sensor system are sent back to autonomous vehicles to enhance the perception ability of autonomous vehicles for benefiting path planning and traffic efficiency at the intersection.The field-testing results show that our method can effectively extend the environmental perception ability and range of autonomous vehicles at the intersection and outperform the PointPillar algorithm and the VoxelRCNN algorithm in detection accuracy.展开更多
While quality assessment is essential for testing, optimizing, benchmarking, monitoring, and inspecting related systems and services, it also plays an essential role in the design of virtually all visual signal proces...While quality assessment is essential for testing, optimizing, benchmarking, monitoring, and inspecting related systems and services, it also plays an essential role in the design of virtually all visual signal processing and communication algorithms, as well as various related decision-making processes. In this paper, we first provide an overview of recently derived quality assessment approaches for traditional visual signals (i.e., 2D images/videos), with highlights for new trends (such as machine learning approaches). On the other hand, with the ongoing development of devices and multimedia services, newly emerged visual signals (e.g., mobile/3D videos) are becoming more and more popular. This work focuses on recent progresses of quality metrics, which have been reviewed for the newly emerged forms of visual signals, which include scalable and mobile videos, High Dynamic Range (HDR) images, image segmentation results, 3D images/videos, and retargeted images.展开更多
Accumulating evidence indicates that inhalation anesthetics induce or increase the risk of cognitive impairment. GLYX-13（rapastinel） acts on the glycine site of N-methyl-D-aspartate receptors（NMDARs） and has been ...Accumulating evidence indicates that inhalation anesthetics induce or increase the risk of cognitive impairment. GLYX-13（rapastinel） acts on the glycine site of N-methyl-D-aspartate receptors（NMDARs） and has been shown to enhance hippocampus-dependent learning and memory function. However, the mechanisms by which GLYX-13 affects learning and memory function are still unclear. In this study, we investigated these mechanisms in a mouse model of long-term anesthesia exposure. Mice were intravenously administered 1 mg/kg GLYX-13 at 2 hours before isoflurane exposure（1.5% for 6 hours）. Cognitive function was assessed using the contextual fear conditioning test and the novel object recognition test. The mRNA expression and phosphorylated protein levels of NMDAR pathway components, N-methyl-D-aspartate receptor subunit 2B（NR2B）-Ca2+/calmodulin dependent protein kinase II（CaMKII）-cyclic adenosine monophosphate response element binding protein（CREB）, in the hippocampus were evaluated by quantitative RT-PCR and western blot assay. Pretreatment with GLYX-13 ameliorated isoflurane exposure-induced cognitive impairment and restored NR2B, CaMKII and CREB mRNA and phosphorylated protein levels. Intracerebroventricular injection of KN93, a selective CaMKII inhibitor, significantly diminished the effect of GLYX-13 on cognitive function and NR2B, CaMKII and CREB levels in the hippocampus. Taken together, our findings suggest that GLYX-13 pretreatment alleviates isoflurane-induced cognitive dysfunction by protecting against perturbation of the NR2B/CaMKII/CREB signaling pathway in the hippocampus. Therefore, GLYX-13 may have therapeutic potential for the treatment of anesthesia-induced cognitive dysfunction. This study was approved by the Experimental Animal Ethics Committee of Drum Tower Hospital affiliated to the Medical College of Nanjing University, China（approval No. 20171102） on November 20, 2017.展开更多
The TM-polarized electromagnetic scattering problem of a two-dimensional inho-mogeneous structure buried in lossy stratified media is presented. Analysis work consists of two parts mainly, derivation of the Green’s f...The TM-polarized electromagnetic scattering problem of a two-dimensional inho-mogeneous structure buried in lossy stratified media is presented. Analysis work consists of two parts mainly, derivation of the Green’s function of a filament buried in lossy stratified media and constitution of the electric field integral equation of the equivalent current caused by the differences between the inhomogeneities and the stratified media. Based on these works, illustrative numerical results are given to model inhomogeneous underground tubes in lossy stratified media, and to describe the scattering field affected by different factors such as permittivity distribution, dimension, and buried depth of the inhomogeneities and so on.展开更多
基金This research was supported by the National Key Research and Development Program of China under Grant No.2017YFB0102502the Beijing Municipal Natural Science Foundation No.L191001+2 种基金the National Natural Science Foundation of China under Grant No.61672082 and 61822101the Newton Advanced Fellowship under Grant No.62061130221the Young Elite Scientists Sponsorship Program by Hunan Provincial Department of Education under Grant No.18B142.
文摘In recent years,autonomous driving technology has made good progress,but the noncooperative intelligence of vehicle for autonomous driving still has many technical bottlenecks when facing urban road autonomous driving challenges.V2I(Vehicle-to-Infrastructure)communication is a potential solution to enable cooperative intelligence of vehicles and roads.In this paper,the RGB-PVRCNN,an environment perception framework,is proposed to improve the environmental awareness of autonomous vehicles at intersections by leveraging V2I communication technology.This framework integrates vision feature based on PVRCNN.The normal distributions transform(NDT)point cloud registration algorithm is deployed both on onboard and roadside to obtain the position of the autonomous vehicles and to build the local map objects detected by roadside multi-sensor system are sent back to autonomous vehicles to enhance the perception ability of autonomous vehicles for benefiting path planning and traffic efficiency at the intersection.The field-testing results show that our method can effectively extend the environmental perception ability and range of autonomous vehicles at the intersection and outperform the PointPillar algorithm and the VoxelRCNN algorithm in detection accuracy.
基金partially supported by the Research Grants Council of the Hong Kong SAR, China (Project CUHK 415712)the Ministry of Education Academic Research Fund (AcRF) Tier 2 in Singapore under Grant No. T208B1218
文摘While quality assessment is essential for testing, optimizing, benchmarking, monitoring, and inspecting related systems and services, it also plays an essential role in the design of virtually all visual signal processing and communication algorithms, as well as various related decision-making processes. In this paper, we first provide an overview of recently derived quality assessment approaches for traditional visual signals (i.e., 2D images/videos), with highlights for new trends (such as machine learning approaches). On the other hand, with the ongoing development of devices and multimedia services, newly emerged visual signals (e.g., mobile/3D videos) are becoming more and more popular. This work focuses on recent progresses of quality metrics, which have been reviewed for the newly emerged forms of visual signals, which include scalable and mobile videos, High Dynamic Range (HDR) images, image segmentation results, 3D images/videos, and retargeted images.
基金supported by the National Natural Science Foundation of China,No.81730033(to XPG),81701371(to TJX),81801380(to XZ)Natural Science Foundation of Jiangsu Province of China,No.BK20170654(to TJX),BK20170129(to XZ)
文摘Accumulating evidence indicates that inhalation anesthetics induce or increase the risk of cognitive impairment. GLYX-13（rapastinel） acts on the glycine site of N-methyl-D-aspartate receptors（NMDARs） and has been shown to enhance hippocampus-dependent learning and memory function. However, the mechanisms by which GLYX-13 affects learning and memory function are still unclear. In this study, we investigated these mechanisms in a mouse model of long-term anesthesia exposure. Mice were intravenously administered 1 mg/kg GLYX-13 at 2 hours before isoflurane exposure（1.5% for 6 hours）. Cognitive function was assessed using the contextual fear conditioning test and the novel object recognition test. The mRNA expression and phosphorylated protein levels of NMDAR pathway components, N-methyl-D-aspartate receptor subunit 2B（NR2B）-Ca2+/calmodulin dependent protein kinase II（CaMKII）-cyclic adenosine monophosphate response element binding protein（CREB）, in the hippocampus were evaluated by quantitative RT-PCR and western blot assay. Pretreatment with GLYX-13 ameliorated isoflurane exposure-induced cognitive impairment and restored NR2B, CaMKII and CREB mRNA and phosphorylated protein levels. Intracerebroventricular injection of KN93, a selective CaMKII inhibitor, significantly diminished the effect of GLYX-13 on cognitive function and NR2B, CaMKII and CREB levels in the hippocampus. Taken together, our findings suggest that GLYX-13 pretreatment alleviates isoflurane-induced cognitive dysfunction by protecting against perturbation of the NR2B/CaMKII/CREB signaling pathway in the hippocampus. Therefore, GLYX-13 may have therapeutic potential for the treatment of anesthesia-induced cognitive dysfunction. This study was approved by the Experimental Animal Ethics Committee of Drum Tower Hospital affiliated to the Medical College of Nanjing University, China（approval No. 20171102） on November 20, 2017.
基金Supported by the National Natural Science Foundation of China
文摘The TM-polarized electromagnetic scattering problem of a two-dimensional inho-mogeneous structure buried in lossy stratified media is presented. Analysis work consists of two parts mainly, derivation of the Green’s function of a filament buried in lossy stratified media and constitution of the electric field integral equation of the equivalent current caused by the differences between the inhomogeneities and the stratified media. Based on these works, illustrative numerical results are given to model inhomogeneous underground tubes in lossy stratified media, and to describe the scattering field affected by different factors such as permittivity distribution, dimension, and buried depth of the inhomogeneities and so on.
