目的分析缺血性脑卒中患者脑CT灌注成像参数、血清CXC型趋化因子配体16(CXCL16)、铁调素25(Hepc25)水平,探讨其对患者预后的预测价值。方法选取2021年9月至2023年9月于本院诊治的缺血性脑卒中患者86例进行回顾性分析,依据静脉溶栓治疗后...目的分析缺血性脑卒中患者脑CT灌注成像参数、血清CXC型趋化因子配体16(CXCL16)、铁调素25(Hepc25)水平,探讨其对患者预后的预测价值。方法选取2021年9月至2023年9月于本院诊治的缺血性脑卒中患者86例进行回顾性分析,依据静脉溶栓治疗后28 d内预后情况分为预后不良组33例、预后良好组53例。比较2组临床资料及脑CT灌注成像参数[脑血流量相对值(rCBF)、脑血容量相对值(rCBV)、对比剂峰值时间相对值(rTTP)]、血清CXCL16、Hepc25水平。分析脑CT灌注成像参数、血清CXCL16、Hepc25水平对预后不良的预测价值。结果预后不良组治疗后7 d rCBF、rCBV低于预后良好组,rTTP高于预后良好组,血清CXCL16、Hepc25水平高于预后良好组(P<0.05);治疗后7 d rCBF、rCBV、rTTP联合血清CXCL16、Hepc25预测治疗后28 d预后不良的曲线下面积(AUC)大于单项指标预测(P<0.05)。结论脑CT灌注成像参数、血清CXCL16、Hepc25水平对缺血性脑卒中患者预后具有一定预测价值,联合检测的预测效能更优。展开更多
Dose estimation and quality control in computed tomography (CT) scanners are useful in controlling the dose of radiation given to patients while tests are carried out. The study was performed in a 16-slice Computed To...Dose estimation and quality control in computed tomography (CT) scanners are useful in controlling the dose of radiation given to patients while tests are carried out. The study was performed in a 16-slice Computed Tomography (CT) system of LightSpeed RT16 Xtra CT scanner. Quality control was done using a vendor-provided QA Phantom, and the six aspects of image quality were measured. For CT dosimetry, Computed Tomography Dose index volume (CTDIvol) was performed using Computed Tomography Dose Index (CTDI) Phantom. CTDI Phantom consists of three parts: Pediatric Head, Adult Head, and Adult Body Phantom. A 10 cm long pencil ion chamber DCT-10 was used to measure the dose at different positions inside the CTDI Phantom. Data were collected using MagicMax Universal software. For dose estimation of the CTDIvol Report of AAPM Task Group, 96 and 111 formalisms were used. For Pediatric Head, Adult Head, and Adult Body Phantom the measured CIDIvol was 61.04 mGy, 48.11 mGy, and 18.08 mGy respectively. The study has shown deviations of 7%, 15%, and 19% between estimated and console-displayed doses for Pediatric Head, Adult Head, and Adult Body scan techniques respectively. The six aspects of image quality measured by QA Phantom were found to be compatible with the specifications of the machine and CTDIvol measured by CTDI Phantom were found within a tolerance limit of ±20%. Hence, the QC and dosimetry of the mentioned machine are within the limit.展开更多
文摘目的分析缺血性脑卒中患者脑CT灌注成像参数、血清CXC型趋化因子配体16(CXCL16)、铁调素25(Hepc25)水平,探讨其对患者预后的预测价值。方法选取2021年9月至2023年9月于本院诊治的缺血性脑卒中患者86例进行回顾性分析,依据静脉溶栓治疗后28 d内预后情况分为预后不良组33例、预后良好组53例。比较2组临床资料及脑CT灌注成像参数[脑血流量相对值(rCBF)、脑血容量相对值(rCBV)、对比剂峰值时间相对值(rTTP)]、血清CXCL16、Hepc25水平。分析脑CT灌注成像参数、血清CXCL16、Hepc25水平对预后不良的预测价值。结果预后不良组治疗后7 d rCBF、rCBV低于预后良好组,rTTP高于预后良好组,血清CXCL16、Hepc25水平高于预后良好组(P<0.05);治疗后7 d rCBF、rCBV、rTTP联合血清CXCL16、Hepc25预测治疗后28 d预后不良的曲线下面积(AUC)大于单项指标预测(P<0.05)。结论脑CT灌注成像参数、血清CXCL16、Hepc25水平对缺血性脑卒中患者预后具有一定预测价值,联合检测的预测效能更优。
文摘Dose estimation and quality control in computed tomography (CT) scanners are useful in controlling the dose of radiation given to patients while tests are carried out. The study was performed in a 16-slice Computed Tomography (CT) system of LightSpeed RT16 Xtra CT scanner. Quality control was done using a vendor-provided QA Phantom, and the six aspects of image quality were measured. For CT dosimetry, Computed Tomography Dose index volume (CTDIvol) was performed using Computed Tomography Dose Index (CTDI) Phantom. CTDI Phantom consists of three parts: Pediatric Head, Adult Head, and Adult Body Phantom. A 10 cm long pencil ion chamber DCT-10 was used to measure the dose at different positions inside the CTDI Phantom. Data were collected using MagicMax Universal software. For dose estimation of the CTDIvol Report of AAPM Task Group, 96 and 111 formalisms were used. For Pediatric Head, Adult Head, and Adult Body Phantom the measured CIDIvol was 61.04 mGy, 48.11 mGy, and 18.08 mGy respectively. The study has shown deviations of 7%, 15%, and 19% between estimated and console-displayed doses for Pediatric Head, Adult Head, and Adult Body scan techniques respectively. The six aspects of image quality measured by QA Phantom were found to be compatible with the specifications of the machine and CTDIvol measured by CTDI Phantom were found within a tolerance limit of ±20%. Hence, the QC and dosimetry of the mentioned machine are within the limit.
