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含Tröger’s base结构聚(苯并噁唑-酰亚胺)热重排分离膜的制备与其气体分离特性研究
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作者 宋映晓 唐傲 +3 位作者 张家霖 董杰 赵昕 张清华 《高分子学报》 北大核心 2025年第8期1358-1368,共11页
设计合成了一种新型含Tröger’s base(TB)结构的二胺单体—2,8-二氨基-4,10-二甲基-6,12-氢-5,11-亚甲二苯并[1,5]二氮辛(TBDA),并将其与2,2′-双(3,4-二羧酸)六氟丙烷二酐(6FDA)和2,2-双(3-氨基-4-羟基苯基)六氟丙烷(APAF)共聚反... 设计合成了一种新型含Tröger’s base(TB)结构的二胺单体—2,8-二氨基-4,10-二甲基-6,12-氢-5,11-亚甲二苯并[1,5]二氮辛(TBDA),并将其与2,2′-双(3,4-二羧酸)六氟丙烷二酐(6FDA)和2,2-双(3-氨基-4-羟基苯基)六氟丙烷(APAF)共聚反应,合成了一系列含邻羟基酰亚胺单元的聚酰亚胺(HPI).在高温下对HPI膜进行热重排处理,获得了兼具TB自聚微孔结构和热重排结构的聚(苯并噁唑-酰亚胺)气体分离膜.研究结果显示,TB自具微孔结构和热重排结构的协同作用抑制了分子链的规整堆砌,使分离膜自由体积增加,从而赋予其优异的气体分离特性.经430℃热重排反应的6FTB1-TR430膜表现出最优异的综合气体分离性能,对CO_(2)、CH_(4)、O_(2)和N_(2)的渗透系数分别为267.6、7.0、57.2和12.5 Barrer(1 Barrer=7.5×10^(−14) cm^(3)(STP)/(cm^(2)·s·Pa),STP表示标准状态,即0℃,1.01×10^(5)Pa),同时,选择性分别达到α(CO_(2)/CH_(4))=38.2及α(O_(2)/N_(2))=4.6.此外,该类分离膜的热分解温度为530~560℃,玻璃化转变温度(Tg)超过400℃,显示出优异的热稳定性.该研究为设计和开发聚酰亚胺类高效气体分离膜提供了新的思路. 展开更多
关键词 Tröger’s base结构 热重排反应 协同作用 气体分离膜
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结合Diffusion-Based WGANGP的变压器油纸绝缘老化状态拉曼光谱检测方法
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作者 陈新岗 敖怡 +5 位作者 张知先 马志鹏 张文轩 万福 况露 罗博文 《光谱学与光谱分析》 北大核心 2025年第8期2164-2173,共10页
提出了一种结合拉曼光谱与扩散模型改进的Wasserstein生成对抗网络(WGANGP)方法,用于提高变压器油纸绝缘老化状态的检测精度。凭借拉曼光谱技术无接触、不损耗的优势,可通过其分析油浸式电力变压器内部油纸绝缘材料的老化产物来评估变... 提出了一种结合拉曼光谱与扩散模型改进的Wasserstein生成对抗网络(WGANGP)方法,用于提高变压器油纸绝缘老化状态的检测精度。凭借拉曼光谱技术无接触、不损耗的优势,可通过其分析油浸式电力变压器内部油纸绝缘材料的老化产物来评估变压器的老化程度。结合深度学习分类模型简化了拉曼光谱数据预处理过程,但此类模型对训练数据的数量和质量有较高要求,由于热加速老化实验周期长,导致可用于训练的有效拉曼光谱数据集相对稀少,限制了分类模型性能。为了解决这一难题,本研究引入了一种新的数据增强方法,即基于扩散模型的WGANGP(Diffusion-Based WGANGP),该方法通过将去噪扩散概率模型的前向加噪过程与WGANGP相结合,向WGANGP中引入实例化的噪声,去除了传统WGANGP的生成器结构中的复杂向上采样过程,简化了数据增强模型结构,有利于模型参数优化。相比于传统GAN及其变体,这种方法不仅保持了变压器油纸绝缘老化样本拉曼光谱数据集的原始特征峰特征与老化程度相关的基线漂移趋势,且与原始数据集特征保持近似的空间分布,生成的数据集信噪比(SNR)为24.84 dB,相比于原始数据集提高了32.11%;同时,也提升了生成样本的多样性,提高了基于深度学习的老化诊断模型的泛化能力、定量分析能力和鲁棒性。实验结果表明,采用Diffusion-Based WGANGP数据增强模型所生成的拉曼光谱数据集,在多个分类模型上的表现均优于其他数据增强方法,特别是在与ResNet-SVM分类模型结合时,在Accuracy(准确性,0.9974)、F1 score(F1分数,0.9969)、Recall(召回率,0.9960)和Precision(精确度,0.9980)四个评价指标上均表现出优势,这表明改进后的数据增强模型能够有效解决变压器老化绝缘油样本稀缺的问题,同时提高了分类模型对变压器老化状态的定量诊断能力。 展开更多
关键词 变压器 油纸绝缘 拉曼光谱 Diffusion-based WGANGP 故障诊断
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孟德尔随机化MR-Base数据库的应用
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作者 蒿花 陈新欢 +3 位作者 姜红 耿辉 马茂 米白冰 《中国循证心血管医学杂志》 2025年第3期270-273,共4页
越来越多的流行病学证据表明,生活方式、饮食习惯等环境因素与多种健康状况之间存在复杂的因果关系。然而,传统的观察性研究易受到混杂因素的影响,无法准确揭示疾病与环境间的因果关系。孟德尔随机化研究(Mendelian Randomization,MR)... 越来越多的流行病学证据表明,生活方式、饮食习惯等环境因素与多种健康状况之间存在复杂的因果关系。然而,传统的观察性研究易受到混杂因素的影响,无法准确揭示疾病与环境间的因果关系。孟德尔随机化研究(Mendelian Randomization,MR)通过遗传变异的随机分配可有效减少混杂因素偏倚,从而更可靠地估计因果效应。MR-Base数据库作为全球最大的孟德尔随机化研究平台,汇集了来自世界各地的遗传数据,为研究者提供了探索遗传变异与健康结局之间因果关系的宝贵资源。本文探讨孟德尔随机化在MR-Base数据库中的应用,旨在介绍该方法的基本原理、数据库的结构与功能,以及如何利用这些数据来探索环境因素与包括心血管疾病、代谢性疾病和精神健康研究等在内的健康结局潜在关联。同时,本文展望了孟德尔随机化方法的未来发展方向,强调了其在精准医疗和公共卫生政策中的潜在作用。 展开更多
关键词 MR-base数据库 孟德尔随机化 遗传变异 工具变量
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Impact of Information and Communication Technologies Based Initiatives: An Attitudinal Change in Students and Teachers
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作者 Surya Narayan Gupta Manohar Sah Akhilesh Chaube 《Applied Mathematics》 2025年第2期190-199,共10页
There is curiosity and awareness throughout the world regarding the role of Information and Communication technologies. This is felt in each and every section of society. Several studies have confirmed and considered ... There is curiosity and awareness throughout the world regarding the role of Information and Communication technologies. This is felt in each and every section of society. Several studies have confirmed and considered information and communication technology’s significance in the field of education. It has not only affected learners but also to the teachers. This paper explores how ICT-based projects affect teachers’ and students’ attitudes. The data was collected through self-prepared attitude scale. It was distributed among the teachers and students of various schools. Two hundred students and one hundred twenty teachers responded to the questionnaire. Analysis was done through the data collected from the teachers as well as from students. The study’s conclusions demonstrated that while there was no significant variation in the attitudes of teachers utilizing different ICT-based programs, there was a substantial difference in the students’ attitude toward learning with different ICT-based programs. 展开更多
关键词 ICT based Initiatives ICT Teacher’s Attitude Student’s Attitude
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Web-Based Platform and Remote Sensing Technology for Monitoring Mangrove Ecosystem
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作者 Evelyn Anthony Rodriguez John Edgar Sualog Anthony +2 位作者 Randy Anthony Quitain Wilma Cledera Delos Santos Ernesto Jr. Benda Rodriguez 《Open Journal of Ecology》 2025年第1期1-10,共10页
Remote sensing and web-based platforms have emerged as vital tools in the effective monitoring of mangrove ecosystems, which are crucial for coastal protection, biodiversity, and carbon sequestration. Utilizing satell... Remote sensing and web-based platforms have emerged as vital tools in the effective monitoring of mangrove ecosystems, which are crucial for coastal protection, biodiversity, and carbon sequestration. Utilizing satellite imagery and aerial data, remote sensing allows researchers to assess the health and extent of mangrove forests over large areas and time periods, providing insights into changes due to environmental stressors like climate change, urbanization, and deforestation. Coupled with web-based platforms, this technology facilitates real-time data sharing and collaborative research efforts among scientists, policymakers, and conservationists. Thus, there is a need to grow this research interest among experts working in this kind of ecosystem. The aim of this paper is to provide a comprehensive literature review on the effective role of remote sensing and web-based platform in monitoring mangrove ecosystem. The research paper utilized the thematic approach to extract specific information to use in the discussion which helped realize the efficiency of digital monitoring for the environment. Web-based platforms and remote sensing represent a powerful tool for environmental monitoring, particularly in the context of forest ecosystems. They facilitate the accessibility of vital data, promote collaboration among stakeholders, support evidence-based policymaking, and engage communities in conservation efforts. As experts confront the urgent challenges posed by climate change and environmental degradation, leveraging technology through web-based platforms is essential for fostering a sustainable future for the forests of the world. 展开更多
关键词 Mangrove Ecosystems MONITORING Remote Sensing Web-based Platform
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Application of Best Evidence-Based in Neonatal Medical Adhesive-Related Skin Injuries
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作者 Zhongxia Li Jing Tan +4 位作者 Xiaoyan Yang Hui Zhou Xia Xu Dingxi Zhu Jin Luo 《Journal of Biosciences and Medicines》 2025年第2期320-329,共10页
Objective: In the Healthy Child Action Enhancement Program (2021-2025), it is proposed to ensure the safety and health of newborns and to promote high-quality development of health. Our department established risk ass... Objective: In the Healthy Child Action Enhancement Program (2021-2025), it is proposed to ensure the safety and health of newborns and to promote high-quality development of health. Our department established risk assessment criteria for medical adhesives in neonates by applying the best evidence in the management program for the reduction of medical adhesive-associated skin injuries in neonates, in terms of the use and removal of adhesives. Methods: A systematic search and quality assessment of topics related to medical adhesive-related skin injury in neonates was conducted to summarize the best evidence and to conduct a quality review in the neonatal unit. Results: After 2 rounds of review, medical and nursing staff in the neonatal unit had a 98% compliance rate for the knowledge of neonatal medical adhesive-related skin injury and a satisfactory compliance rate for the other 9 indicators;after the application of the evidence, the incidence of neonatal medical adhesive-related skin injury was significantly lower than that before the application of the evidence, and the differences were statistically significant (P Conclusion: The application of the best evidence-based management program in neonatal medical adhesive-associated skin injury can reduce the incidence of neonatal medical adhesive-associated skin injury, reduce neonatal infections, and improve the integrity of the protective skin barrier in neonates. 展开更多
关键词 EVIDENCE-baseD Nursing Management NEONATES Medical Adhesive-Related Skin Injury SATISFACTION
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Effect of Hf and Ta on creep deformation behaviors of PM Ni-based superalloys
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作者 Hao-peng ZHANG Jia-ming BAI +4 位作者 Xin-yu LI Xiao-kun LI Jian JIA Jian-tao LIU Yi-wen ZHANG 《Transactions of Nonferrous Metals Society of China》 2025年第3期849-862,共14页
Four powder metallurgy(PM)Ni-based superalloys with different Hf and Ta contents were creep-tested at 650℃ and 970 MPa,700℃ and 770 MPa,and 750℃ and 580 MPa,respectively.The effect of Hf and Ta on creep deformation... Four powder metallurgy(PM)Ni-based superalloys with different Hf and Ta contents were creep-tested at 650℃ and 970 MPa,700℃ and 770 MPa,and 750℃ and 580 MPa,respectively.The effect of Hf and Ta on creep deformation behaviors of the superalloys was studied from multiple scales by SEM,electron backscatter diffraction(EBSD),and aberration-corrected scanning transmission electron microscope(AC-STEM).The results showed that Hf and Ta suppressed the intergranular fracture and initiation of cracks during the acceleration creep stage,which prolonged the creep rupture time.Hf and Ta inhibited the stacking faults extending and the dislocation climbing and promoted the Suzuki segregation of W during the steady-state creep stage,which reduced the minimum creep rate and delayed the start time of the acceleration creep stage.The Suzuki segregation of Co,Cr,Mo,Ti,Nb,W,and Ta along stacking faults was observed after Hf and Ta addition,leading to the localized phase transformation in the γ′phase,and the stacking fault phase was chemically disordered.This study provided ideas for the composition design of novel PM Ni-based superalloys and theoretical foundations for the combined addition of Hf and Ta. 展开更多
关键词 PM Ni-based superalloy HF TA creep deformation behaviors Suzuki segregation
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Evidence-Based Practice of Nutrition Management in Chronic Heart Failure Patients Based on Knowledge-to-Action Transformation Model
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作者 Jing Zhang Junjun Liu 《Open Journal of Applied Sciences》 2025年第2期400-410,共11页
Objective: To develop a best-evidence-based optimal nutrition management plan for patients with chronic heart failure, apply it in clinical practice, and evaluate its effectiveness. Methods: Use the KTA knowledge tran... Objective: To develop a best-evidence-based optimal nutrition management plan for patients with chronic heart failure, apply it in clinical practice, and evaluate its effectiveness. Methods: Use the KTA knowledge translation model to guide evidence-based practice in nutrition management, and compare the nutritional status, cardiac function status, quality of life, and quality review indicators of chronic heart failure patients before and after the application of evidence. Results: After the application of evidence, the nutritional status indicators (MNA-SF score, albumin, hemoglobin) of two groups of heart failure patients significantly increased compared to before the application of evidence, with statistically significant differences (p Conclusion: The KTA knowledge translation model provides methodological guidance for the implementation of evidence-based practice for heart failure patients. This evidence-based practice project is beneficial for improving the outcomes of malnutrition in chronic heart failure patients and is conducive to standardizing nursing pathways, thereby promoting the improvement of nursing quality. 展开更多
关键词 Chronic Heart Failure Knowledge Transformation Mode Nutrition Management Evidence-based Practice
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基于Agent-Based模型和群智能算法的供电信息通信监控中心威胁感知方法
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作者 陶程栋 梅峰 王强强 《计算技术与自动化》 2025年第2期60-65,共6页
针对采样结果泛化程度较差导致感知粒子覆盖率较低、监控中心威胁样本召回率较低的问题,设计了基于Agent-Based模型和群智能算法的供电信息通信监控中心威胁感知方法。首先,对供电信息通信监控中心数据进行采样和分析,并对采样结果进行... 针对采样结果泛化程度较差导致感知粒子覆盖率较低、监控中心威胁样本召回率较低的问题,设计了基于Agent-Based模型和群智能算法的供电信息通信监控中心威胁感知方法。首先,对供电信息通信监控中心数据进行采样和分析,并对采样结果进行泛化处理和归约计算;然后,基于Agent-Based模型构建供电信息通信监控中心威胁本体溯源函数,并计算Agent的感知能力;最后,采用群智能算法对构建威胁本体溯源函数的感知结果进行优化处理,实现对供电信息通信监控中心威胁的精确感知;最终完成供电信息通信监控中心威胁感知方法设计。实验结果表明,该方法在实际应用中,召回率更高,感知效果更好。 展开更多
关键词 Agent-based模型 群智能算法 供电信息 通信监控中心 感知方法 方法设计
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Establishing and Sustaining Academic and Local Health Collaborations: A Case Study of Practice-Based Teaching and Workforce Development
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作者 Marissa Varrasso Stacey Cunnington +6 位作者 Eva Nelson Alyson Codner Meredith Hurley Ami Mitchell Amanda Flanagan Donna McGrath Jacey Greece 《Health》 2025年第1期23-48,共26页
The pandemic highlighted significant gaps in the public health infrastructure impacted by shortages of public health workers, an undertrained workforce, and years of disinvestment. These gaps required innovative probl... The pandemic highlighted significant gaps in the public health infrastructure impacted by shortages of public health workers, an undertrained workforce, and years of disinvestment. These gaps required innovative problem-solving by public health agencies (PHAs), including local health departments (LHDs), to respond to rapidly changing community conditions during and after the pandemic. Many schools and programs of public health (SPPH) worked with PHAs to mobilize public health (PH) students through practice-based teaching (PBT). Current research indicates PBT benefits all stakeholders—PHAs, students, faculty, SPPH, and ultimately the community served. However, more research is needed on the utility of PBT in addressing a community’s systemic public health issues, the extent to which the academic-community collaboration enhances a PHA’s capacity, and the impact of the pedagogy on preparing the workforce for an evolving PH landscape. This paper examines the process of a semester-long PBT course, guided by the PBT STEPS framework, which includes five steps from collaboration to implementation to evaluation of a PBT course. The collaborating PHA and its student group addressed community trauma and resilience issues during the semester. Additionally, it examines the longer-term impacts after the semester for the PHA, community, and the workforce by 1) conducting a formative evaluation to understand needs and gaps in the community;2) redesigning an intervention that merged the results of the formative evaluation with the intervention developed during the semester;and 3) securing funding and resources for intervention sustainability. Through the documentation of a post-course partnership between an LHD and faculty at a large school of public health, this case study illustrates the potential for PBT to lay the foundation for ongoing research that supports more impactful interventions for PHAs while bolstering the workforce abilities of students as future practitioners. 展开更多
关键词 Academic and Community Collaborations Practice-based Teaching Public Health Training Workforce Development Curriculum Design Community Trauma COVID-19
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A Dynamic Knowledge Base Updating Mechanism-Based Retrieval-Augmented Generation Framework for Intelligent Question-and-Answer Systems
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作者 Yu Li 《Journal of Computer and Communications》 2025年第1期41-58,共18页
In the context of power generation companies, vast amounts of specialized data and expert knowledge have been accumulated. However, challenges such as data silos and fragmented knowledge hinder the effective utilizati... In the context of power generation companies, vast amounts of specialized data and expert knowledge have been accumulated. However, challenges such as data silos and fragmented knowledge hinder the effective utilization of this information. This study proposes a novel framework for intelligent Question-and-Answer (Q&A) systems based on Retrieval-Augmented Generation (RAG) to address these issues. The system efficiently acquires domain-specific knowledge by leveraging external databases, including Relational Databases (RDBs) and graph databases, without additional fine-tuning for Large Language Models (LLMs). Crucially, the framework integrates a Dynamic Knowledge Base Updating Mechanism (DKBUM) and a Weighted Context-Aware Similarity (WCAS) method to enhance retrieval accuracy and mitigate inherent limitations of LLMs, such as hallucinations and lack of specialization. Additionally, the proposed DKBUM dynamically adjusts knowledge weights within the database, ensuring that the most recent and relevant information is utilized, while WCAS refines the alignment between queries and knowledge items by enhanced context understanding. Experimental validation demonstrates that the system can generate timely, accurate, and context-sensitive responses, making it a robust solution for managing complex business logic in specialized industries. 展开更多
关键词 Retrieval-Augmented Generation Question-and-Answer Large Language Models Dynamic Knowledge base Updating Mechanism Weighted Context-Aware Similarity
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Evaluating the Potential Impact of Oat-Based Skincare on Celiac Disease Patients with Compromised Skin Integrity
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作者 Kelly Frasier Nicole Werpachowski +3 位作者 Milena Dragovic Alyssa Forsyth Alicia Podwojniak Brittani Remé 《Journal of Biosciences and Medicines》 2025年第2期129-147,共19页
Oats, frequently incorporated into skincare formulations for their anti-inflammatory, moisturizing, and barrier-repairing properties, may present an overlooked risk to individuals with celiac disease, particularly whe... Oats, frequently incorporated into skincare formulations for their anti-inflammatory, moisturizing, and barrier-repairing properties, may present an overlooked risk to individuals with celiac disease, particularly when applied to compromised skin. Although pure oats are inherently gluten-free, the widespread contamination with gluten-containing grains like wheat, barley, or rye during agricultural and processing stages introduces the potential for gluten exposure through topical application. This raises important questions about whether gluten proteins, when applied to damaged skin, might penetrate the epidermal barrier and contribute to immune responses in genetically predisposed celiac patients, given that even minute amounts of gluten can trigger systemic symptoms. Emerging evidence suggests that transdermal absorption of gluten peptides through impaired skin integrity might bypass the gastrointestinal route, yet the precise mechanisms and clinical significance of this pathway remain poorly understood. The role of compromised skin in facilitating gluten absorption and the possible activation of CD4+ T-cells, mimicking gastrointestinal pathways, warrants further investigation. Additionally, the ability of gluten peptides to reach deeper dermal layers and potentially enter the systemic circulation remains speculative, though theoretically possible in severely disrupted skin barriers. Without clinical and molecular studies to determine the risk of topical gluten exposure, particularly in celiac patients with skin injuries, there remains a potential for undetected immune activation and subsequent adverse health outcomes in this sensitive population. 展开更多
关键词 Oat-based Skincare Anti-Inflammatory Skin Barrier Celiac Disease Gluten Contamination Compromised Skin Transdermal Absorption Gluten Peptides Immune Activation Gluten-Free Formulations Topical Exposure Risks
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AcidBasePred:基于深度学习的蛋白酸碱耐受性预测平台
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作者 黄蓉 张鹤渐 +9 位作者 吴敏 门志月 初环宇 白杰 常宏 程健 廖小平 刘玉万 宋亚囝 江会锋 《生物工程学报》 CAS CSCD 北大核心 2024年第12期4670-4681,共12页
酶的结构和活性受环境pH值的影响。了解酶对极端pH值的适应机制并进行区分,对于阐明酶的分子机制和工业应用具有重要意义。本研究利用ESM-2蛋白质语言模型对最适pH值大于等于9和/或小于等于5的微生物的分泌蛋白进行编码,分别获得了4772... 酶的结构和活性受环境pH值的影响。了解酶对极端pH值的适应机制并进行区分,对于阐明酶的分子机制和工业应用具有重要意义。本研究利用ESM-2蛋白质语言模型对最适pH值大于等于9和/或小于等于5的微生物的分泌蛋白进行编码,分别获得了47725条和66079条数据。在此基础上,本研究构建了一个基于氨基酸序列判别蛋白酸碱耐受性的深度学习模型。该模型准确率显著超过其他方法,在测试集上的整体准确率为94.8%,精确率为91.8%、召回率为93.4%。同时搭建了一个web预测平台(https://enzymepred.biodesign.ac.cn),用户可以直接提交酶的蛋白质序列,预测其酸碱耐受性。本研究加速了酶在生物技术、制药和化工等多个领域的应用进程,为工业酶的快速筛选与优化提供了强有力的工具。 展开更多
关键词 蛋白质序列 酸碱耐受性 深度学习 预测平台
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OceanBase分布式关系数据库架构与技术 被引量:4
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作者 阳振坤 杨传辉 +3 位作者 韩富晟 王国平 杨志丰 成肖君 《计算机研究与发展》 EI CSCD 北大核心 2024年第3期540-554,共15页
关系数据库是当今社会的关键信息基础设施,互联网和数字化带来了高并发和海量数据,传统关系数据库均为集中式架构,处理能力和存储容量都捉襟见肘.OceanBase分布式关系数据库基于通用PC服务器,不仅实现了在线水平伸缩,还实现了机房故障... 关系数据库是当今社会的关键信息基础设施,互联网和数字化带来了高并发和海量数据,传统关系数据库均为集中式架构,处理能力和存储容量都捉襟见肘.OceanBase分布式关系数据库基于通用PC服务器,不仅实现了在线水平伸缩,还实现了机房故障自动无损容灾以及高倍率数据压缩等,已经应用于金融、政务、通信和互联网等行业.介绍了OceanBase分布式关系数据库的系统架构和关键技术,包括分布式事务处理、基于LSM-tree的存储系统以及分布式SQL优化器.详细阐述了OceanBase数据库的高可用和数据一致性,包括RPO为0和RTO小于8 s.也介绍了OceanBase数据库多租户机制,即采用了集群内原生多租户设计,在集群内实现多个互相独立的数据库服务.基于Sysbench和TPC-H评测基准,对比实验结果表明:1)在单机模式下,OceanBase的性能是MySQL的1.27倍至2倍多;2)在单主模式下,OceanBase的性能是MySQL的1.25倍至近2倍;3)在多主模式下,OceanBase的性能是MySQL的1.09倍至3.1倍,对于OLAP的复杂查询,OceanBase的性能是MySQL的6倍到327倍. 展开更多
关键词 关系数据库 分布式事务 基于LSM-tree存储 分布式SQL优化器 多租户
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黄河流域生态保护和高质量发展战略实施成效与推进策略 被引量:13
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作者 苗长虹 夏成 +3 位作者 金凤君 马丽 张文忠 傅伯杰 《自然资源学报》 北大核心 2025年第3期569-583,共15页
黄河流域是中华文明的重要发祥地、历史演进的主干枢纽、伟大复兴的关键支撑,黄河流域生态保护和高质量发展事关全面推进中国式现代化的全局。黄河流域是一个具有综合性、整体性、多样性、复杂性同时又与外部区域具有近远程耦合关系的人... 黄河流域是中华文明的重要发祥地、历史演进的主干枢纽、伟大复兴的关键支撑,黄河流域生态保护和高质量发展事关全面推进中国式现代化的全局。黄河流域是一个具有综合性、整体性、多样性、复杂性同时又与外部区域具有近远程耦合关系的人口-经济-社会-生态-文化复合系统。黄河国家战略实施五年来,流域生态环境质量发生转折性变化,维护国家粮食、能源安全能力显著提升,城乡区域发展迈出坚实步伐,文化传承发展实现新突破,对内对外开放合作迈向更高水平;流域产业经济在创新、绿色、协调等方面取得明显进展,科技创新支撑能力有所增强,产业结构转型初见成效,资源环境效率大幅度改善。锚定2035年基本实现社会主义现代化的宏伟目标,需要在更好地统筹发展与安全的前提下,紧紧抓住培育发展新质生产力的机会窗口,以人口高质量发展推动经济-社会-环境协同升级,统筹协调好人-水-粮-能-碳-生态之间的纽带关系,加快实体性有边界的黄河国家文化公园建设,探索协同实现人口-经济-社会-生态-文化一体化高质量发展的大河流域现代化道路;通过持续推动区域协同发展、科技创新引领、消费升级拉动、高水平开放,推动流域产业绿色低碳转型升级;发挥黄河“几”字弯地区国家能源安全压舱石和绿色能源重要生产基地的作用,加快推进黄河“几”字弯地区国家能源安全保障基地建设。构建以人水关系为核心的黄河流域人地系统耦合模型,从纽带关系的角度理解整体性,从临界阈值的角度理解系统性,从远程耦合的角度理解协同性,是深入推进黄河流域生态保护和高质量发展的重要科技支撑。 展开更多
关键词 生态保护 高质量发展 国家能源安全保障基地 人水关系 黄河流域
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基于清单管理的护理风险管理信息化平台的构建及应用 被引量:4
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作者 席祖洋 李茶香 +3 位作者 刘静兰 郭蓉 田飞 魏永婷 《中国护理管理》 北大核心 2025年第1期101-106,共6页
目的:构建基于清单管理的护理风险管理信息化平台,并探讨其应用效果,以期为护理风险防范及控制提供参考借鉴。方法:以4R危机管理理论为指导查找临床护理中的风险点,系统检索、整合证据并引入临床情境,形成风险管理操作清单并构建信息化... 目的:构建基于清单管理的护理风险管理信息化平台,并探讨其应用效果,以期为护理风险防范及控制提供参考借鉴。方法:以4R危机管理理论为指导查找临床护理中的风险点,系统检索、整合证据并引入临床情境,形成风险管理操作清单并构建信息化管理平台,设置风险预警机制。于2021年1月起开始临床应用,比较应用前后护理不良事件发生例数、服务效率指标、护士满意度等指标的差异。结果:在高风险药品、仪器设备、高风险护理操作、疾病并发症、宣教与护患沟通、专科病区风险、护理敏感指标等8个方面建立342个风险管理清单并植入信息化平台,应用后我院护理不良事件发生率由246.74/10万下降至42.48/10万,年度变化百分比(APC)为-61.50%(P<0.001);服务效率和护士满意度稳步提升,效果显著。结论:基于清单管理的护理风险管理信息化平台能够有效减少护理不良事件的发生率并提高服务效率,具有一定的借鉴价值。 展开更多
关键词 清单 风险管理 护理管理 循证护理 护理信息化
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促进深层学习的项目式课程教学创新设计理论与方法 被引量:2
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作者 郝莉 冯晓云 +1 位作者 郭永春 李君 《高等工程教育研究》 北大核心 2025年第3期6-18,共13页
随着工业化社会向知识经济时代转变,高等教育需要培养能够深刻理解复杂概念并进行创新的毕业生。项目式学习根植于建构主义发现,其本质是让学生参与到与专业人士从事的专业活动类似的实践中,通过努力解决与其自身相关的有意义的问题,获... 随着工业化社会向知识经济时代转变,高等教育需要培养能够深刻理解复杂概念并进行创新的毕业生。项目式学习根植于建构主义发现,其本质是让学生参与到与专业人士从事的专业活动类似的实践中,通过努力解决与其自身相关的有意义的问题,获得对所学知识更深刻的理解。然而,尽管项目式课程已广泛应用于工程等学科的人才培养当中,却往往存在项目选题不当、任务设置不合理、学习过程缺乏设计、指导和支持不足以及学生未获得深层理解等问题,导致教学目标无法有效达成,效果甚至不及传统讲授式教学。对此,本文指出,提升项目式课程教学质量的关键,在于通过教学创新设计促进学生深层学习。我们从专家技能、学习方法和学习动机三个视角审视深层学习,随后建立项目式教学设计准则并提出具体的教学策略,以此为基础结合案例给出教学目标与任务迭代过程两个关键环节的设计方法,从而探讨如何在项目式课程中促进学生有效实施深层学习,帮助他们在新情境中灵活应用和创造知识。 展开更多
关键词 深层学习 项目式课程 专家技能 脚手架
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植物肉产业发展趋势、国内外差距及政策建议 被引量:2
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作者 刘洪霞 张学彪 +1 位作者 曲春红 赵伟 《粮油食品科技》 北大核心 2025年第3期138-145,共8页
目前全球植物肉生产主要以植物蛋白为原料,其中基于大豆蛋白生产的植物肉在市场中占绝对优势。我国作为非转基因大豆最大生产国,与大豆主产国相比,从价格角度提升国产大豆竞争力后劲不足,但未来可考虑从植物肉生产环节入手解决国产大豆... 目前全球植物肉生产主要以植物蛋白为原料,其中基于大豆蛋白生产的植物肉在市场中占绝对优势。我国作为非转基因大豆最大生产国,与大豆主产国相比,从价格角度提升国产大豆竞争力后劲不足,但未来可考虑从植物肉生产环节入手解决国产大豆过剩问题。为此,本文从全球植物肉产业发展现状和趋势及国内外产业发展差距进行了系统归纳和深入分析,提出了我国植物肉产业发展面临的一系列挑战,包括监管政策不完善、产品本身有缺陷、消费者对产品认知不足等。最后,从加强政策扶持与引导、推动科技创新与研发以及扩大市场认知与接受度等方面提出促进我国植物肉产业发展的政策建议,旨在为振兴我国大豆产业,进一步推动植物肉产业发展提供研究基础和案例参考。 展开更多
关键词 植物肉 大豆 蛋白质 政策建议
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液压支架大功率供液系统的现状与智能化发展趋势 被引量:4
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作者 赵继云 曹超 +4 位作者 王浩 泮延召 黄笛 韩静 苗运江 《煤炭学报》 北大核心 2025年第1期676-693,共18页
煤矿井下采煤工作面供液系统为液压支架提供高压大流量液压动力,其性能和可靠性是综采成套装备安全智能高效工作的关键。为进一步保障采煤工作面支护安全,保证液压支架跟机速度,总结供液系统发展现状、提炼智能供液关键技术需求和发展... 煤矿井下采煤工作面供液系统为液压支架提供高压大流量液压动力,其性能和可靠性是综采成套装备安全智能高效工作的关键。为进一步保障采煤工作面支护安全,保证液压支架跟机速度,总结供液系统发展现状、提炼智能供液关键技术需求和发展方向是实现大功率供液系统性能跃升的首要环节。以当前液压支架供液系统大功率化、智能化发展为背景,系统地归纳分析了液压支架大功率供液系统的构型和工作原理,论述并比较了多种泵控和阀控构型的稳压控制方法;着眼于大功率供液系统压力和流量连续控制需求,分析对比了相关研究中高压大流量高水基比例卸载阀和比例流量阀的先导驱动、结构原理、工作参数等方面的特点,指出了高压大流量高水基连续控制阀研发的重点难点;针对支撑按需供液精准控制的长管路动力传递环节建模和稳压控制方法,论述了液压支架长管路非恒定流动力学建模方法的现实意义,总结比较了面向液压支架周期复合动作的强时变供液系统稳压控制策略和方法;围绕系统安全可靠性保障需求,综述了包含监测和诊断的供液系统智能运维技术研究现状。聚焦综采工作面可靠高效应用需求和高水基液压系统智能化技术前沿,分析了限制供液系统控制性能突破的理论瓶颈,全面地总结了目前大功率供液系统关键技术研发的不足;论述了从元件和系统层面提升控制性能及其可靠性以支撑大功率液压支架供液系统智能化发展的必要性,并提出了液压支架供液系统的未来技术发展方向。 展开更多
关键词 液压支架 大功率 高水基 供液系统 稳压控制
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慢性肝病“郁、虚、湿、毒、瘀”核心病机探讨 被引量:3
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作者 叶永安 靳茜 +1 位作者 李小科 杜宏波 《世界中医药》 北大核心 2025年第9期1562-1566,共5页
基于长期临床实践,参见现代社会环境和生活方式,结合文献资料、流调等提出慢性肝病“郁、虚、湿、毒、瘀”病机理论。郁、虚、湿、毒、瘀贯穿慢性肝病全程,五者既可单独致病,亦可复合兼夹、互为因果。其中,郁、虚为发病之本,湿、毒、瘀... 基于长期临床实践,参见现代社会环境和生活方式,结合文献资料、流调等提出慢性肝病“郁、虚、湿、毒、瘀”病机理论。郁、虚、湿、毒、瘀贯穿慢性肝病全程,五者既可单独致病,亦可复合兼夹、互为因果。其中,郁、虚为发病之本,湿、毒、瘀为致病之标。“郁、虚”以肝郁脾虚为核心,治疗以“肝脾同调”为基础;“湿”性缠绵难愈,辨别湿浊、痰湿和湿热等辨“质”施治;“毒”复杂多变,分清湿毒、痰毒、瘀毒、癌毒等辨“类”施治;“瘀”为进展之要,视血瘀轻重辨“度”施治。 展开更多
关键词 湿 慢性肝病 病机 辨证施治
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