A hair tonic containing 1.0%Arctium lappa root extract(ALRE)was evaluated for its efficacy and tolerability in Chinese consumers.ALRE was selected based on its ability to promote Collagen Type XVII Alpha 1(COL17A1)syn...A hair tonic containing 1.0%Arctium lappa root extract(ALRE)was evaluated for its efficacy and tolerability in Chinese consumers.ALRE was selected based on its ability to promote Collagen Type XVII Alpha 1(COL17A1)synthesis,along with other active ingredients targeting scalp health and follicular regeneration.In vitro assays confirmed that ALRE significantly enhanced COL17A1 expression.A 28-day clinical trial involving Chinese participants demonstrated that the tonic reduced hair loss by 37.61%and increased local hair density by 26.63%,with no reported adverse effects.These findings validate the product’s effectiveness in a distinct consumer population and highlight the importance of integrating mechanistic insights with clinical validation.Further research should explore long-term efficacy and demographic-specific responses to optimize its application.展开更多
[Objectives]Based on bibliometric methods,the evolution path and knowledge structure of shampoo product research in China were systematically analyzed,with a focus on the composition,efficacy,and mechanisms of traditi...[Objectives]Based on bibliometric methods,the evolution path and knowledge structure of shampoo product research in China were systematically analyzed,with a focus on the composition,efficacy,and mechanisms of traditional Chinese medicine shampoos,aiming to reveal the shifting patterns of core technological focuses at different stages and identify key future research directions.[Methods]Using a sample of 515 publications from CNKI journals between 2005 and 2025,CiteSpace 6.3.R1 was employed to construct multi-dimensional networks of authors,institutions,and keywords.Burst detection,keyword and cluster analyses,and time zone mapping were applied to track disciplinary dynamics.[Results]The analysis on the annual number of publications indicated that research on shampoo products underwent multiple phases including initial development,growth,fluctuation,peak,and adjustment from 2005 to 2025,with an overall upward trend.The significant differences between the collaboration network density of core authors and the strength of institutional cooperation indicated a need for academia to enhance cross-institutional collaborative innovation mechanisms.Keyword clustering analysis and co-occurrence mapping revealed that the research on traditional Chinese medicine shampoo products,known for their natural,mild,and non-irritating characteristics,demonstrates notable advantages in dandruff removal,anti-hair loss,hair growth,and scalp health management,which have become current research hotspots,providing data-driven decision-making support for technological upgrading and industry-academia-research integration in the field.[Conclusions]The bibliometric analysis based on 515 publications indicates that the overall development direction of shampoo products will comprehensively advance toward refined efficacy and personalized customization,greener and more natural ingredients,technological innovation and industry-academia-research collaboration,market segmentation and diversified development,as well as safety and efficacy evaluation.This study provides theoretical support for the innovation of specialized traditional Chinese medicine shampoo products.展开更多
Using sodium laureth sulfate(AES)as reference,the effects of different pH values on the foam properties of four amino acid surfactants(sodium lauroyl sarcosinate,lauroyl alanine,disodium cocoyl glutamate,sodium methyl...Using sodium laureth sulfate(AES)as reference,the effects of different pH values on the foam properties of four amino acid surfactants(sodium lauroyl sarcosinate,lauroyl alanine,disodium cocoyl glutamate,sodium methyl cocoyl taurate)were compared.On the basis,the effects of amino acid surfactants on foam performance,flocculation behavior,hair color protection efficacy and sebum removal capacity were studied when AES was completely or partially replaced by amino acid surfactant,and the correlation between the structure of amino acid surfactant and these properties was discussed.Compared with AES,the foam performance of sodium lauroyl sarcosinate,lauroyl alanine and disodium cocoyl glutamate were significantly affected by pH value,and sodium methyl cocoyl taurate was less affected.The foam stability of shampoo system can be enhanced by the combination of amino acid surfactant,and the foam performance of shampoo system can be significantly improved by the combination of sodium methyl cocoyl taurate.All the four amino acid surfactants can prolong the flocculation time of shampoo,and the effect of disodium cocoyl glutamate was the most obvious.The hair color protection efficacy of disodium cocoyl glutamate and sodium methyl cocoyl taurate were better than AES.The degreasing power of disodium cocoyl glutamate was weaker than that of AES,and the degreasing power of sodium lauroyl sarcosinate,lauroyl alanine and sodium methyl cocoyl taurate were stronger than that of AES.展开更多
Hair coloring has emerged as an integral part of the cosmetic industry,particularly in response to the increasing global aging phenomenon.The natural melanin analog,polydopamine(PDA),has garnered considerable attentio...Hair coloring has emerged as an integral part of the cosmetic industry,particularly in response to the increasing global aging phenomenon.The natural melanin analog,polydopamine(PDA),has garnered considerable attention as an eco-friendly hair dye,and several kinds of polymerization ways of dopamine(DA)have been proposed including alkali catalysis,metal ion catalysis,strong oxidants,and enzyme-mediated oxidation reactions and polymerizations.Yet the controllability of polymerization and potential toxicity of involved metal ions are still in question.Inspired by the photoprotective mechanism in human skin,we have developed the melanin-inspired hair dyeing strategy that allowed for the in situ oxidative polymerization of DA under ultraviolet(UV)light.This polymerization was triggered by photobase generators(PBGs),a class of compounds that produced organic bases upon UV and sunlight irradiation.The resulting hair showed an adjustable color from light brown to black by tuning the ratio of DA and PBG(DA@PBG),the concentration of DA,and light exposure time.The dyed hairs showed excellent washing resistance and superior anti-static properties.Furthermore,Hair Color Spray DA@PBG also demonstrated a desirable hair dyeing effect and excellent biosecurity by simply spraying it on the hair under sunlight.This novel sunlight-induced method provided a new direction towards the preparation of natural hair dyes and could promote the development of green and safe hair dyes in colorful and brilliant artistic-grade hair coloring.展开更多
文摘A hair tonic containing 1.0%Arctium lappa root extract(ALRE)was evaluated for its efficacy and tolerability in Chinese consumers.ALRE was selected based on its ability to promote Collagen Type XVII Alpha 1(COL17A1)synthesis,along with other active ingredients targeting scalp health and follicular regeneration.In vitro assays confirmed that ALRE significantly enhanced COL17A1 expression.A 28-day clinical trial involving Chinese participants demonstrated that the tonic reduced hair loss by 37.61%and increased local hair density by 26.63%,with no reported adverse effects.These findings validate the product’s effectiveness in a distinct consumer population and highlight the importance of integrating mechanistic insights with clinical validation.Further research should explore long-term efficacy and demographic-specific responses to optimize its application.
基金Supported by Undergraduate Innovation and Entrepreneurship Program of Faculty of Chinese Medicine Science of Guangxi University of Chinese Medicine (Autonomous Region Level) (S202413643051)Guangxi First-class Discipline Construction Project (GJKY[2022]1).
文摘[Objectives]Based on bibliometric methods,the evolution path and knowledge structure of shampoo product research in China were systematically analyzed,with a focus on the composition,efficacy,and mechanisms of traditional Chinese medicine shampoos,aiming to reveal the shifting patterns of core technological focuses at different stages and identify key future research directions.[Methods]Using a sample of 515 publications from CNKI journals between 2005 and 2025,CiteSpace 6.3.R1 was employed to construct multi-dimensional networks of authors,institutions,and keywords.Burst detection,keyword and cluster analyses,and time zone mapping were applied to track disciplinary dynamics.[Results]The analysis on the annual number of publications indicated that research on shampoo products underwent multiple phases including initial development,growth,fluctuation,peak,and adjustment from 2005 to 2025,with an overall upward trend.The significant differences between the collaboration network density of core authors and the strength of institutional cooperation indicated a need for academia to enhance cross-institutional collaborative innovation mechanisms.Keyword clustering analysis and co-occurrence mapping revealed that the research on traditional Chinese medicine shampoo products,known for their natural,mild,and non-irritating characteristics,demonstrates notable advantages in dandruff removal,anti-hair loss,hair growth,and scalp health management,which have become current research hotspots,providing data-driven decision-making support for technological upgrading and industry-academia-research integration in the field.[Conclusions]The bibliometric analysis based on 515 publications indicates that the overall development direction of shampoo products will comprehensively advance toward refined efficacy and personalized customization,greener and more natural ingredients,technological innovation and industry-academia-research collaboration,market segmentation and diversified development,as well as safety and efficacy evaluation.This study provides theoretical support for the innovation of specialized traditional Chinese medicine shampoo products.
文摘Using sodium laureth sulfate(AES)as reference,the effects of different pH values on the foam properties of four amino acid surfactants(sodium lauroyl sarcosinate,lauroyl alanine,disodium cocoyl glutamate,sodium methyl cocoyl taurate)were compared.On the basis,the effects of amino acid surfactants on foam performance,flocculation behavior,hair color protection efficacy and sebum removal capacity were studied when AES was completely or partially replaced by amino acid surfactant,and the correlation between the structure of amino acid surfactant and these properties was discussed.Compared with AES,the foam performance of sodium lauroyl sarcosinate,lauroyl alanine and disodium cocoyl glutamate were significantly affected by pH value,and sodium methyl cocoyl taurate was less affected.The foam stability of shampoo system can be enhanced by the combination of amino acid surfactant,and the foam performance of shampoo system can be significantly improved by the combination of sodium methyl cocoyl taurate.All the four amino acid surfactants can prolong the flocculation time of shampoo,and the effect of disodium cocoyl glutamate was the most obvious.The hair color protection efficacy of disodium cocoyl glutamate and sodium methyl cocoyl taurate were better than AES.The degreasing power of disodium cocoyl glutamate was weaker than that of AES,and the degreasing power of sodium lauroyl sarcosinate,lauroyl alanine and sodium methyl cocoyl taurate were stronger than that of AES.
基金financially supported by the National Natural Science Foundation of China(No.52225311)the Fundamental Research Funds for Central Universities.
文摘Hair coloring has emerged as an integral part of the cosmetic industry,particularly in response to the increasing global aging phenomenon.The natural melanin analog,polydopamine(PDA),has garnered considerable attention as an eco-friendly hair dye,and several kinds of polymerization ways of dopamine(DA)have been proposed including alkali catalysis,metal ion catalysis,strong oxidants,and enzyme-mediated oxidation reactions and polymerizations.Yet the controllability of polymerization and potential toxicity of involved metal ions are still in question.Inspired by the photoprotective mechanism in human skin,we have developed the melanin-inspired hair dyeing strategy that allowed for the in situ oxidative polymerization of DA under ultraviolet(UV)light.This polymerization was triggered by photobase generators(PBGs),a class of compounds that produced organic bases upon UV and sunlight irradiation.The resulting hair showed an adjustable color from light brown to black by tuning the ratio of DA and PBG(DA@PBG),the concentration of DA,and light exposure time.The dyed hairs showed excellent washing resistance and superior anti-static properties.Furthermore,Hair Color Spray DA@PBG also demonstrated a desirable hair dyeing effect and excellent biosecurity by simply spraying it on the hair under sunlight.This novel sunlight-induced method provided a new direction towards the preparation of natural hair dyes and could promote the development of green and safe hair dyes in colorful and brilliant artistic-grade hair coloring.
