A facile one-pot strategy for the synthesis ofα,β-unsaturated amides via an I_(2)/t-butylhydroperoxide(TBHP)-mediated oxidative system has been reported.The methodology achieves efficient construction of a series of...A facile one-pot strategy for the synthesis ofα,β-unsaturated amides via an I_(2)/t-butylhydroperoxide(TBHP)-mediated oxidative system has been reported.The methodology achieves efficient construction of a series ofα,β-unsaturated amides through oxidative coupling of allylbenzenes with N,N-dialkylformamides under mild conditions.Notably,N,N-dialkylformamides serve as both solvents and reactants in this protocol,significantly enhancing the atom economy of transformation.展开更多
Calcium carbide,a bulky and cheap raw chemical,is traditionally depolymerized by water to release acetylene,allowing the downstream organic transformation.In this study,hydrogen sulfide(H_(2)S),an industrial waste gas...Calcium carbide,a bulky and cheap raw chemical,is traditionally depolymerized by water to release acetylene,allowing the downstream organic transformation.In this study,hydrogen sulfide(H_(2)S),an industrial waste gas,has been exploited to depolymerize calcium carbide,which represents a strategy for the comprehensive utilization of both hydrogen sulfide and calcium carbide.As a proof of concept,a three-component condensation reaction was established to prepare thioamides directly from hydrogen sulfide and calcium carbide in high yields.Leveraging the unique properties of thioamides that possess both nucleophilic sulfur and electrophilic carbon sites,a series of novel tandem reactions were further developed to construct structurally diverse heterocyclic compounds.Our strategy not only provides a new chemical pathway for calcium carbide depolymerization,but also offers a solution for the utilization of hazardous hydrogen sulfide gas.More importantly,this approach facilitates the comprehensive and sustainable utilization of the calcium carbide resource.展开更多
文摘A facile one-pot strategy for the synthesis ofα,β-unsaturated amides via an I_(2)/t-butylhydroperoxide(TBHP)-mediated oxidative system has been reported.The methodology achieves efficient construction of a series ofα,β-unsaturated amides through oxidative coupling of allylbenzenes with N,N-dialkylformamides under mild conditions.Notably,N,N-dialkylformamides serve as both solvents and reactants in this protocol,significantly enhancing the atom economy of transformation.
基金the National Natural Science Foundation of China(Nos.22379075,22471114,U23A20528)the Group Project of Developing Inner Mongolia through Talents from the Talents Work Leading Group under the CPC Inner Mongolia Autonomous Regional Committee(No.2025TEL04)+2 种基金Natural Science Foundation of Inner Mongolia Autonomous Region(No.2024LHMS02011)the Innovative Research Team in Universities of Inner Mongolia Autonomous Region(No.NMGIRT2212)Basic Scientific Research Funds of Universities directly under the Inner Mongolia Autonomous Region(Nos.ZTY2025013 and JY20240076)for financial support。
文摘Calcium carbide,a bulky and cheap raw chemical,is traditionally depolymerized by water to release acetylene,allowing the downstream organic transformation.In this study,hydrogen sulfide(H_(2)S),an industrial waste gas,has been exploited to depolymerize calcium carbide,which represents a strategy for the comprehensive utilization of both hydrogen sulfide and calcium carbide.As a proof of concept,a three-component condensation reaction was established to prepare thioamides directly from hydrogen sulfide and calcium carbide in high yields.Leveraging the unique properties of thioamides that possess both nucleophilic sulfur and electrophilic carbon sites,a series of novel tandem reactions were further developed to construct structurally diverse heterocyclic compounds.Our strategy not only provides a new chemical pathway for calcium carbide depolymerization,but also offers a solution for the utilization of hazardous hydrogen sulfide gas.More importantly,this approach facilitates the comprehensive and sustainable utilization of the calcium carbide resource.
