Multi-organ-on-a-chip(MOOC)technology represents a pivotal direction in the organ-on-a-chip field,seeking to emulate the complex interactions of multiple human organs in vitro through microfluidic systems.This technol...Multi-organ-on-a-chip(MOOC)technology represents a pivotal direction in the organ-on-a-chip field,seeking to emulate the complex interactions of multiple human organs in vitro through microfluidic systems.This technology overcomes the limitations of traditional single-organ models,providing a novel platform for investigating complex disease mechanisms and evaluating drug efficacy and toxicity.Although it demonstrates broad application prospects,its development still faces critical bottlenecks,including inadequate physiological coupling between organs,short functional maintenance durations,and limited real-time monitoring capabilities.Contemporary research is advancing along three key directions,including functional coupling,sensor integration,and full-process automation systems,to propel the technology toward enhanced levels of physiological relevance and predictive accuracy.展开更多
针对现场可编程门阵列(Field Programmable Gate Array,FPGA)电声测试数据采集电路的优化策略进行深入研究。在电声测试领域,数据采集精准性与效率极其关键,而FPGA凭借高性能属性得到广泛应用。在电声测试数据收集阶段,FPGA在采样率和...针对现场可编程门阵列(Field Programmable Gate Array,FPGA)电声测试数据采集电路的优化策略进行深入研究。在电声测试领域,数据采集精准性与效率极其关键,而FPGA凭借高性能属性得到广泛应用。在电声测试数据收集阶段,FPGA在采样率和多通道同步等方面面临难题。为化解这些困扰,制定一系列优化办法,包括高速模数转换器(Analog to Digital Converter,ADC)接口设计事项及多通道并行的架构体系,以增强电路性能,为电声测试给予更可靠且高效的数据收集支撑。展开更多
星载抗辐射多频多模导航器件单粒子效应(SEE)数据获取为器件能否在轨可靠使用提供重要参考。在介绍公司自研导航器件组成结构和抗辐照加固设计的基础上,通过设计专用试验板,在FPGA上进行DFT-SCAN、MBIST向量测试。利用重离子加速器完成...星载抗辐射多频多模导航器件单粒子效应(SEE)数据获取为器件能否在轨可靠使用提供重要参考。在介绍公司自研导航器件组成结构和抗辐照加固设计的基础上,通过设计专用试验板,在FPGA上进行DFT-SCAN、MBIST向量测试。利用重离子加速器完成空间单粒子辐照的地面模拟实验,以此确定导航器件的单粒子数据。通过实验数据计算得到导航器件SEE指标数据:抗单粒子锁定LET≥81.4 MeV·cm^(2)/mg,在GEO轨道、ADAMS 90%最坏环境模型、3 mm Al屏蔽条件下,器件SCAN链模式单粒子翻转概率为6.80×10^(-8)次/(天·位),SRAM模式单粒子翻转概率为5.61×10^(-11)次/(天·位),单粒子功能中断概率为5.75×10^(-5)次/(天·器件),为在轨航天器导航接收机使用提供依据和参考。展开更多
基金supported by the Shenzhen Medical Research Fund(Grant No.A2303049)Guangdong Basic and Applied Basic Research(Grant No.2023A1515010647)+1 种基金National Natural Science Foundation of China(Grant No.22004135)Shenzhen Science and Technology Program(Grant No.RCBS20210706092409020,GXWD20201231165807008,20200824162253002).
文摘Multi-organ-on-a-chip(MOOC)technology represents a pivotal direction in the organ-on-a-chip field,seeking to emulate the complex interactions of multiple human organs in vitro through microfluidic systems.This technology overcomes the limitations of traditional single-organ models,providing a novel platform for investigating complex disease mechanisms and evaluating drug efficacy and toxicity.Although it demonstrates broad application prospects,its development still faces critical bottlenecks,including inadequate physiological coupling between organs,short functional maintenance durations,and limited real-time monitoring capabilities.Contemporary research is advancing along three key directions,including functional coupling,sensor integration,and full-process automation systems,to propel the technology toward enhanced levels of physiological relevance and predictive accuracy.
文摘针对现场可编程门阵列(Field Programmable Gate Array,FPGA)电声测试数据采集电路的优化策略进行深入研究。在电声测试领域,数据采集精准性与效率极其关键,而FPGA凭借高性能属性得到广泛应用。在电声测试数据收集阶段,FPGA在采样率和多通道同步等方面面临难题。为化解这些困扰,制定一系列优化办法,包括高速模数转换器(Analog to Digital Converter,ADC)接口设计事项及多通道并行的架构体系,以增强电路性能,为电声测试给予更可靠且高效的数据收集支撑。
文摘星载抗辐射多频多模导航器件单粒子效应(SEE)数据获取为器件能否在轨可靠使用提供重要参考。在介绍公司自研导航器件组成结构和抗辐照加固设计的基础上,通过设计专用试验板,在FPGA上进行DFT-SCAN、MBIST向量测试。利用重离子加速器完成空间单粒子辐照的地面模拟实验,以此确定导航器件的单粒子数据。通过实验数据计算得到导航器件SEE指标数据:抗单粒子锁定LET≥81.4 MeV·cm^(2)/mg,在GEO轨道、ADAMS 90%最坏环境模型、3 mm Al屏蔽条件下,器件SCAN链模式单粒子翻转概率为6.80×10^(-8)次/(天·位),SRAM模式单粒子翻转概率为5.61×10^(-11)次/(天·位),单粒子功能中断概率为5.75×10^(-5)次/(天·器件),为在轨航天器导航接收机使用提供依据和参考。
