目的探讨AD8和简易智能状态检查量表(mini-mental state examination,MMSE)联合使用在军队健康体检人群中筛查认知功能障碍的特异性和敏感性。方法选择2013年1月1日~12月31日在解放军总医院接受常规健康体检的军队人群1723例,进行AD8和M...目的探讨AD8和简易智能状态检查量表(mini-mental state examination,MMSE)联合使用在军队健康体检人群中筛查认知功能障碍的特异性和敏感性。方法选择2013年1月1日~12月31日在解放军总医院接受常规健康体检的军队人群1723例,进行AD8和MMSE测评。结果 1723例接受AD8测评中,AD8≥2分326例(18.9%)。161例主诉认知功能减退者同时接受MMSE测评,AD8≥2分84例(52.2%),MMSE异常78例(48.4%)。临床诊断痴呆66例(41.0%),其中AD8筛查阳性46例(69.7%),MMSE异常55例(83.3%)。ROC曲线分析显示,AD8+MMSE联合筛查痴呆的特异性从AD8单项测试的60.0%提高到91.6%。协方差分析显示,在调整年龄的影响因素后,AD8+MMSE双异常者连线A评分较认知正常者明显升高,MMSE、延迟回忆、执行功能、工作记忆、词语流畅性评分较认知正常者明显降低,差异有统计学意义(P<0.01)。结论健康体检时AD8+MMSE联合应用可以提高检出痴呆患者的特异性和可靠性,便于在基层医疗卫生机构推广使用。展开更多
Dear Editor,Post-traumatic stress disorder(PTSD)is a major issue for military personnel,with prevalence rates between 1%and 35%in veterans^([1]),significantly higher than in the general population^([2]).Psychological ...Dear Editor,Post-traumatic stress disorder(PTSD)is a major issue for military personnel,with prevalence rates between 1%and 35%in veterans^([1]),significantly higher than in the general population^([2]).Psychological resources,particularly hope,can protect against PTSD and promote post-traumatic growth^([3]).Hope,conceptualized as both a trait and a state,contributes to well-being and resilience and is negatively associated with PTSD symptoms,representing a psychological factor while mitigating the impact of trauma by fostering resilience and adaptive coping mechanisms.展开更多
文摘目的探讨AD8和简易智能状态检查量表(mini-mental state examination,MMSE)联合使用在军队健康体检人群中筛查认知功能障碍的特异性和敏感性。方法选择2013年1月1日~12月31日在解放军总医院接受常规健康体检的军队人群1723例,进行AD8和MMSE测评。结果 1723例接受AD8测评中,AD8≥2分326例(18.9%)。161例主诉认知功能减退者同时接受MMSE测评,AD8≥2分84例(52.2%),MMSE异常78例(48.4%)。临床诊断痴呆66例(41.0%),其中AD8筛查阳性46例(69.7%),MMSE异常55例(83.3%)。ROC曲线分析显示,AD8+MMSE联合筛查痴呆的特异性从AD8单项测试的60.0%提高到91.6%。协方差分析显示,在调整年龄的影响因素后,AD8+MMSE双异常者连线A评分较认知正常者明显升高,MMSE、延迟回忆、执行功能、工作记忆、词语流畅性评分较认知正常者明显降低,差异有统计学意义(P<0.01)。结论健康体检时AD8+MMSE联合应用可以提高检出痴呆患者的特异性和可靠性,便于在基层医疗卫生机构推广使用。
基金supported by the Institut de Recherche Biomédicale des Armées(Brétigny-sur-Orge,France).
文摘Dear Editor,Post-traumatic stress disorder(PTSD)is a major issue for military personnel,with prevalence rates between 1%and 35%in veterans^([1]),significantly higher than in the general population^([2]).Psychological resources,particularly hope,can protect against PTSD and promote post-traumatic growth^([3]).Hope,conceptualized as both a trait and a state,contributes to well-being and resilience and is negatively associated with PTSD symptoms,representing a psychological factor while mitigating the impact of trauma by fostering resilience and adaptive coping mechanisms.
