AIM:To assess the visual acuity and visual quality of cataract patients who received femtosecond laser-assisted cataract surgery(FLACS)and multifocal intraocular lens(MIOL)implantation with an improved polishing techn...AIM:To assess the visual acuity and visual quality of cataract patients who received femtosecond laser-assisted cataract surgery(FLACS)and multifocal intraocular lens(MIOL)implantation with an improved polishing technique during a 1-year follow-up period.METHODS:This study included 74 eyes from 37 patients,comprising 17 males and 20 females,with a mean age of 51.74±7.80 years.Using a coin toss method,one eye per patient was randomly selected for improved anterior capsular polishing,while the other eye received standard irrigation/aspiration(I/A)polishing.The polishing group consisted of 37 eyes,including 21 right and 16 left eyes,while the control group comprised the contralateral fellow eyes of the same individuals in the polishing group.Visual acuity and quality of the patients were evaluated before surgery and at 1 wk,1,6,and 12 mo after surgery.The OPD-Scan III was utilized to assess high-order aberrations,while the optical quality analysis system(OQAS)was employed to evaluate modulation transfer function(MTF cutoff),Strehl ratio(SR),and objective scatter index(OSI)for the purpose of visual quality assessment.Paired t-tests and repeated measures analysis of variance(ANOVA)were utilized to compare the results,and the SNK-q post hoc test was applied to identify significant differences.RESULTS:The polishing group’s uncorrected distant visual acuity(UDVA)and uncorrected near visual acuity(UNVA)significantly improved 1-week post-surgery(all P<0.05).At 12-months,UDVA,UNVA,and corrected distant visual acuity(CDVA)were better than the control group(P<0.05).The MTF cutoff,SR,OSI,and high-order aberrations in the polishing group also showed significant improvements compared to the control group at 12 mo(P<0.05).CONCLUSION:The improved capsular polishing method has been demonstrated to effectively maintain visual acuity and visual quality in patients with MIOL after FLACS within 1 a.展开更多
目的分析先天性白内障(CC)的影响因素,构建并验证人工智能筛查诊断系统。方法选取新疆维吾尔自治区人民医院2018年12月至2023年12月收治的300例CC儿童作为CC组,同期选取新疆维吾尔自治区人民医院眼科300名健康儿童作为对照组。利用数码...目的分析先天性白内障(CC)的影响因素,构建并验证人工智能筛查诊断系统。方法选取新疆维吾尔自治区人民医院2018年12月至2023年12月收治的300例CC儿童作为CC组,同期选取新疆维吾尔自治区人民医院眼科300名健康儿童作为对照组。利用数码裂隙灯照相系统,用复方托吡卡胺滴眼液散瞳后采集婴幼儿眼前节数字图像。通过单因素分析及多因素logistic回归分析影响因素。整合Canny算子、霍夫变换定位晶状体区域,结合深度残差网络及随机森林、自适应增强算法,构建CC智能诊断系统。采用四重交叉验证对同期南疆地区150例CC患儿及120名健康对照进行内外部验证,评估系统效能。结果单因素分析结果显示,不同一级亲属遗传史、早产、母亲孕前2个月或孕期感染、低出生体重、出生后1 min Apgar评分<4分的婴儿先天性白内障的发生情况比较,差异有统计学意义(P<0.05);多因素回归分析显示,一级亲属遗传史、母亲孕前2个月或孕期感染、早产、出生后1 min Apgar评分<4分、低出生体重均为CC的影响因素(P<0.05);RF模型诊断效能优于Ada,双侧CC筛查准确性及敏感性更高;重要性排序显示,一级亲属遗传史、母亲孕前2个月或孕期感染及低出生体重为前3位影响因素。结论一级亲属遗传史、母亲孕前2个月或孕期感染、早产、出生后1 min Apgar评分<4分、低出生体重均为CC的影响因素,构建人工智能筛查诊断系统可为建立适合新疆地区的CC早期临床筛查及防治策略提供参考。展开更多
文摘AIM:To assess the visual acuity and visual quality of cataract patients who received femtosecond laser-assisted cataract surgery(FLACS)and multifocal intraocular lens(MIOL)implantation with an improved polishing technique during a 1-year follow-up period.METHODS:This study included 74 eyes from 37 patients,comprising 17 males and 20 females,with a mean age of 51.74±7.80 years.Using a coin toss method,one eye per patient was randomly selected for improved anterior capsular polishing,while the other eye received standard irrigation/aspiration(I/A)polishing.The polishing group consisted of 37 eyes,including 21 right and 16 left eyes,while the control group comprised the contralateral fellow eyes of the same individuals in the polishing group.Visual acuity and quality of the patients were evaluated before surgery and at 1 wk,1,6,and 12 mo after surgery.The OPD-Scan III was utilized to assess high-order aberrations,while the optical quality analysis system(OQAS)was employed to evaluate modulation transfer function(MTF cutoff),Strehl ratio(SR),and objective scatter index(OSI)for the purpose of visual quality assessment.Paired t-tests and repeated measures analysis of variance(ANOVA)were utilized to compare the results,and the SNK-q post hoc test was applied to identify significant differences.RESULTS:The polishing group’s uncorrected distant visual acuity(UDVA)and uncorrected near visual acuity(UNVA)significantly improved 1-week post-surgery(all P<0.05).At 12-months,UDVA,UNVA,and corrected distant visual acuity(CDVA)were better than the control group(P<0.05).The MTF cutoff,SR,OSI,and high-order aberrations in the polishing group also showed significant improvements compared to the control group at 12 mo(P<0.05).CONCLUSION:The improved capsular polishing method has been demonstrated to effectively maintain visual acuity and visual quality in patients with MIOL after FLACS within 1 a.
文摘目的分析先天性白内障(CC)的影响因素,构建并验证人工智能筛查诊断系统。方法选取新疆维吾尔自治区人民医院2018年12月至2023年12月收治的300例CC儿童作为CC组,同期选取新疆维吾尔自治区人民医院眼科300名健康儿童作为对照组。利用数码裂隙灯照相系统,用复方托吡卡胺滴眼液散瞳后采集婴幼儿眼前节数字图像。通过单因素分析及多因素logistic回归分析影响因素。整合Canny算子、霍夫变换定位晶状体区域,结合深度残差网络及随机森林、自适应增强算法,构建CC智能诊断系统。采用四重交叉验证对同期南疆地区150例CC患儿及120名健康对照进行内外部验证,评估系统效能。结果单因素分析结果显示,不同一级亲属遗传史、早产、母亲孕前2个月或孕期感染、低出生体重、出生后1 min Apgar评分<4分的婴儿先天性白内障的发生情况比较,差异有统计学意义(P<0.05);多因素回归分析显示,一级亲属遗传史、母亲孕前2个月或孕期感染、早产、出生后1 min Apgar评分<4分、低出生体重均为CC的影响因素(P<0.05);RF模型诊断效能优于Ada,双侧CC筛查准确性及敏感性更高;重要性排序显示,一级亲属遗传史、母亲孕前2个月或孕期感染及低出生体重为前3位影响因素。结论一级亲属遗传史、母亲孕前2个月或孕期感染、早产、出生后1 min Apgar评分<4分、低出生体重均为CC的影响因素,构建人工智能筛查诊断系统可为建立适合新疆地区的CC早期临床筛查及防治策略提供参考。
