目的:探究小儿远视屈光不正性弱视应用欠矫正与足矫正方案治疗的临床效果。方法:回顾性分析2019年5月至2022年5月于本院治疗的88例176眼远视屈光不正性弱视患儿临床资料。所有患儿均接受配镜矫正治疗,依据患儿的配镜处方与睫状肌麻痹验...目的:探究小儿远视屈光不正性弱视应用欠矫正与足矫正方案治疗的临床效果。方法:回顾性分析2019年5月至2022年5月于本院治疗的88例176眼远视屈光不正性弱视患儿临床资料。所有患儿均接受配镜矫正治疗,依据患儿的配镜处方与睫状肌麻痹验光结果的差异,将其分为欠矫正组(球镜度数相差≥1.5D,共42例84眼)和足矫正组(球镜度数相差≤0.25D,共46例92眼)。于治疗后1年、2年、3年时,通过验光检查比较两组患儿在治疗过程中的矫正视力及屈光度水平变化。结果:治疗后1年、治疗后2年、治疗后3年时,两组患儿屈光度均降低,且欠矫正组屈光度更低(P<0.05);治疗后,欠矫正组屈光度改变量、球镜改变量、散光改变量较足矫正组更高(P<0.05);治疗后,治疗后1年、治疗后2年、治疗后3年时,两组患儿对数最小分辨角(Logarithm of Minimal Angle of Resolution,LogMAR)均降低,且欠矫正组LogMAR更低(P<0.05)。结论:欠矫正方案在降低小儿远视屈光不正性弱视的屈光度方面效果显著,在临床实践中,应根据患儿的具体情况和需求,权衡两种矫正方式的利弊,选择最适宜的矫正方案,以实现最佳的治疗效果。展开更多
AIM:To determine the prevalence of tropia,phoria,and abnormality of near point of convergence(NPC),along with associated ocular symptoms,in high school students.METHODS:This cross-sectional study was conducted in Erbi...AIM:To determine the prevalence of tropia,phoria,and abnormality of near point of convergence(NPC),along with associated ocular symptoms,in high school students.METHODS:This cross-sectional study was conducted in Erbil,Iraq.The target population consisted of high school students selected through a multi-stage cluster sampling method.Comprehensive visual examinations were performed for all students,including measurement of uncorrected and corrected visual acuity,objective and subjective refraction,and distance and near cover tests.NPC was evaluated using a single 6/12 visual target mounted on a centrally positioned Gulden fixation stick.Ocular symptoms were investigated through interviews.RESULTS:Of the 996 selected students,921 participated in the study.Of them,543(58.96%)were female,and their ages ranged from 13 to 22y.The prevalence of tropia was 3.58%[95%confidence interval(CI):2.38%-4.78%],observed in 3.44%of males and 3.68%of females.Exotropia(1.95%,95%CI:1.06%-2.85%)was more common than esotropia(1.52%,95%CI:0.73%-2.31%).The 15.42%(95%CI:13.09%-17.75%)of students had phoria.Exophoria(13.79%,95%CI:11.56%-16.02%)was significantly more prevalent than esophoria(1.63%,95%CI:0.81%-2.45%).The prevalence of NPC abnormality in the total study population was 24.97%(95%CI:22.18%-27.77%).It was 26.72%(95%CI:22.26%-31.18%)in males and 23.76%(95%CI:20.18%-27.34%)in females(P=0.307).The most common symptom in phoria was headache(86.62%,95%CI:81.02%-92.22%),followed by tired or sore eyes(61.97%,95%CI:53.99%-69.96%).The most common symptoms in tropia were blurry vision(93.94%,95%CI:79.77%-99.26%)and difficulty concentrating(87.88%,95%CI:76.74%-99.01%).CONCLUSION:Among Erbil’s high school students,the prevalence of strabismus,particularly the exodeviation type,is relatively high,and a significant percentage of students have NPC abnormalities.Addressing and correcting these binocular vision problems,due to their associated visual symptoms,can lead to an improvement in students’quality of life and academic performance.展开更多
先天性眼外肌纤维化(congenital fibrosis of extraocular muscles,CFEOM)综合征是一种具有遗传倾向的先天性眼外肌功能障碍性疾病,患者典型表现为先天性非进展性眼外肌麻痹、限制性眼球固定及上睑下垂,发病率为1/23万~1/25万。本文报...先天性眼外肌纤维化(congenital fibrosis of extraocular muscles,CFEOM)综合征是一种具有遗传倾向的先天性眼外肌功能障碍性疾病,患者典型表现为先天性非进展性眼外肌麻痹、限制性眼球固定及上睑下垂,发病率为1/23万~1/25万。本文报告中南大学湘雅二医院收治的1个CFEOM 3型家系,先证者为10岁女性患儿,临床表现为右眼向内偏斜合并右眼上睑下垂。全外显子组测序发现患者在TUBB3基因上发生c.904G>A杂合突变。对家系中其他成员检测的结果提示患者母亲也携带相同突变,表现为左眼眼睑下垂。先后予患儿斜视矫正手术、上睑下垂矫正手术,术后症状得到明显改善。对于出现先天性眼外肌运动障碍及上睑下垂的患者,应高度重视遗传学检测在确诊及家系分析中的价值;同时,个体化的手术干预可显著改善患者的功能及外观。展开更多
AIM:To summarize publication trends in the field of strabismus over the past 30y and predict future research hotspots.METHODS:A total of 2915 English-language articles and reviews on strabismus,published between 1993 ...AIM:To summarize publication trends in the field of strabismus over the past 30y and predict future research hotspots.METHODS:A total of 2915 English-language articles and reviews on strabismus,published between 1993 and 2022,were retrieved from the Web of Science Core Collection.Bibliometric analyses were performed using VOSviewer and CiteSpace software to explore publication trends,as well as the contributions and collaborative networks of countries/regions,authors,institutions,and journals.RESULTS:The annual number of publications on strabismus showed a consistent upward trend.The United States(USA)maintained a leading position in this research field while Republic of Korea and China emerged as rapidly advancing contributors over the last decade.The University of California,Los Angeles ranked as the most productive institution,and Jonathan M.Holmes from USA was the most productive author.Journal of AAPOS was the leading journal with the most strabismus publications,whereas the two most highly cited articles were both published in Ophthalmology.Co-occurrence analysis identified pivotal keywords and burst terms,including intermittent exotropia(IXT),acute acquired comitant esotropia(AACE),functional magnetic resonance imaging(fMRI),and surgical treatment,which were confirmed as predominant and frontier topics.CONCLUSION:This study provides a comprehensive bibliometric analysis of strabismus research,revealing the evolution of research hotspots over the past 30y and outlining several cutting-edge directions for future investigation.展开更多
文摘目的:探究小儿远视屈光不正性弱视应用欠矫正与足矫正方案治疗的临床效果。方法:回顾性分析2019年5月至2022年5月于本院治疗的88例176眼远视屈光不正性弱视患儿临床资料。所有患儿均接受配镜矫正治疗,依据患儿的配镜处方与睫状肌麻痹验光结果的差异,将其分为欠矫正组(球镜度数相差≥1.5D,共42例84眼)和足矫正组(球镜度数相差≤0.25D,共46例92眼)。于治疗后1年、2年、3年时,通过验光检查比较两组患儿在治疗过程中的矫正视力及屈光度水平变化。结果:治疗后1年、治疗后2年、治疗后3年时,两组患儿屈光度均降低,且欠矫正组屈光度更低(P<0.05);治疗后,欠矫正组屈光度改变量、球镜改变量、散光改变量较足矫正组更高(P<0.05);治疗后,治疗后1年、治疗后2年、治疗后3年时,两组患儿对数最小分辨角(Logarithm of Minimal Angle of Resolution,LogMAR)均降低,且欠矫正组LogMAR更低(P<0.05)。结论:欠矫正方案在降低小儿远视屈光不正性弱视的屈光度方面效果显著,在临床实践中,应根据患儿的具体情况和需求,权衡两种矫正方式的利弊,选择最适宜的矫正方案,以实现最佳的治疗效果。
文摘AIM:To determine the prevalence of tropia,phoria,and abnormality of near point of convergence(NPC),along with associated ocular symptoms,in high school students.METHODS:This cross-sectional study was conducted in Erbil,Iraq.The target population consisted of high school students selected through a multi-stage cluster sampling method.Comprehensive visual examinations were performed for all students,including measurement of uncorrected and corrected visual acuity,objective and subjective refraction,and distance and near cover tests.NPC was evaluated using a single 6/12 visual target mounted on a centrally positioned Gulden fixation stick.Ocular symptoms were investigated through interviews.RESULTS:Of the 996 selected students,921 participated in the study.Of them,543(58.96%)were female,and their ages ranged from 13 to 22y.The prevalence of tropia was 3.58%[95%confidence interval(CI):2.38%-4.78%],observed in 3.44%of males and 3.68%of females.Exotropia(1.95%,95%CI:1.06%-2.85%)was more common than esotropia(1.52%,95%CI:0.73%-2.31%).The 15.42%(95%CI:13.09%-17.75%)of students had phoria.Exophoria(13.79%,95%CI:11.56%-16.02%)was significantly more prevalent than esophoria(1.63%,95%CI:0.81%-2.45%).The prevalence of NPC abnormality in the total study population was 24.97%(95%CI:22.18%-27.77%).It was 26.72%(95%CI:22.26%-31.18%)in males and 23.76%(95%CI:20.18%-27.34%)in females(P=0.307).The most common symptom in phoria was headache(86.62%,95%CI:81.02%-92.22%),followed by tired or sore eyes(61.97%,95%CI:53.99%-69.96%).The most common symptoms in tropia were blurry vision(93.94%,95%CI:79.77%-99.26%)and difficulty concentrating(87.88%,95%CI:76.74%-99.01%).CONCLUSION:Among Erbil’s high school students,the prevalence of strabismus,particularly the exodeviation type,is relatively high,and a significant percentage of students have NPC abnormalities.Addressing and correcting these binocular vision problems,due to their associated visual symptoms,can lead to an improvement in students’quality of life and academic performance.
基金Supported by National Natural Science Foundation of China(No.82020108006,No.81730025).
文摘AIM:To summarize publication trends in the field of strabismus over the past 30y and predict future research hotspots.METHODS:A total of 2915 English-language articles and reviews on strabismus,published between 1993 and 2022,were retrieved from the Web of Science Core Collection.Bibliometric analyses were performed using VOSviewer and CiteSpace software to explore publication trends,as well as the contributions and collaborative networks of countries/regions,authors,institutions,and journals.RESULTS:The annual number of publications on strabismus showed a consistent upward trend.The United States(USA)maintained a leading position in this research field while Republic of Korea and China emerged as rapidly advancing contributors over the last decade.The University of California,Los Angeles ranked as the most productive institution,and Jonathan M.Holmes from USA was the most productive author.Journal of AAPOS was the leading journal with the most strabismus publications,whereas the two most highly cited articles were both published in Ophthalmology.Co-occurrence analysis identified pivotal keywords and burst terms,including intermittent exotropia(IXT),acute acquired comitant esotropia(AACE),functional magnetic resonance imaging(fMRI),and surgical treatment,which were confirmed as predominant and frontier topics.CONCLUSION:This study provides a comprehensive bibliometric analysis of strabismus research,revealing the evolution of research hotspots over the past 30y and outlining several cutting-edge directions for future investigation.
