目的评估人工角膜移植术后患者的视觉相关生活质量及其影响因素。方法采用横断面研究方法收集2004-01/2019-12月在作者医院接受过单眼MICOF人工角膜或BostonⅠ型人工角膜植入术的127例双眼角膜盲患者人口学资料及临床资料,并采用中文版...目的评估人工角膜移植术后患者的视觉相关生活质量及其影响因素。方法采用横断面研究方法收集2004-01/2019-12月在作者医院接受过单眼MICOF人工角膜或BostonⅠ型人工角膜植入术的127例双眼角膜盲患者人口学资料及临床资料,并采用中文版国家眼科研究所视功能问卷-25项(Chinese national eye institute visual function questionnaire-25,CHI-NEI-VFQ-25)评估患者视觉相关生活质量。采用皮尔逊相关分析和斯皮尔曼相关分析术后手术眼BCVA与视觉相关生活质量的相关性。采用多元逐步线性回归分析视觉相关生活质量的影响因素。结果127例患者中,术后随访(4.31±3.16)年,CHI-NEI-VFQ-25综合得分为(44.18±18.40)分。手术至问卷调查时间间隔<2年的患者远距离活动、心理健康、依赖性、驾驶能力得分和综合评分较手术至问卷调查时间间隔≥2年者更低(P均<0.05);接受米赫(MICOF)人工角膜植入患者眼部疼痛、近距离活动、角色困难得分和综合评分较接受波士顿(Boston)Ⅰ型者更高(P均<0.05)。手术眼的术后最佳矫正视力(best corrected visual acuity,BCVA)与CHI-NEI-VFQ-25综合评分(r=-0.775,P<0.001)及除了眼部疼痛(r=0.139,P=0.120)以外的其他子量表得分均呈负相关(P均<0.05)。术后手术眼BCVA和手术至问卷调查时间间隔<2年对CHI-NEI-VFQ-25综合评分具有负向预测作用(β=-21.546,P<0.001;β=-5.698,P=0.029)。结论双眼角膜盲患者的视觉相关生活质量在接受单眼人工角膜手术后有所改善。术后视觉相关生活质量的主要影响因素是手术眼术后视力,但人工角膜植入手术至问卷调查时间间隔是否<2年也会影响视觉相关生活质量。展开更多
BACKGROUND Glaucoma is the leading cause of irreversible blindness worldwide,with 60.5 million affected individuals,of whom 11 million are from India.Due to its asymptomatic nature,the disease largely remains underdia...BACKGROUND Glaucoma is the leading cause of irreversible blindness worldwide,with 60.5 million affected individuals,of whom 11 million are from India.Due to its asymptomatic nature,the disease largely remains underdiagnosed or diagnosed in advanced stages,where little can be done to salvage functional vision.The literature suggests that a lack of knowledge is one of the reasons for its grave consequences.Assessment of awareness is the first step in planning management.Several studies have been conducted in the Indian community,but data from healthcare providers,who play a significant role in educating the masses directly or indirectly,are limited.AIM To identify awareness,knowledge,and attitudes about glaucoma among healthcare workers in a tertiary center in India.METHODS This cross-sectional study was conducted at a tertiary care institute in Eastern India.Data were collected from 423 participants by systematic stratified sampling after Institutional Ethics Committee approval via a pretested,self-designed,semistructured,validated questionnaire.Statistical analyses were performed using the Statistical Package for Social Sciences Software v22.0.Continuous variables are expressed as the means±SD for parametric values and medians with interquartile ranges for nonparametric values.The associations between the variables were studied via multivariate linear and logistic regression.P<0.05 was considered statistically significant.RESULTS Most respondents were 20–30 years old(n=345,81.6%).The knowledge regarding glaucoma was good,and almost 56.3%of the participants gained knowledge from their medical training.The majority were aware that it has a familial predisposition and is secondary to high intraocular pressure,leading to irreversible peripheral vision loss.Only 42%knew about the life-long requirements of treatment.The resident group scored highest on knowledgeand attitude-based questions,whereas the faculty group scored highest on practice-based questions.Although 62%of the nursing staff had good attitude scores,their knowledge and practice scores were lower.The occupation group response difference was statistically significant(P<0.05)for all the knowledge-based questions.CONCLUSION Although the majority of healthcare providers are aware of glaucoma,there is a dearth of knowledge about treatment modalities.Education via seminars and media can improve their knowledge,attitudes,and practices.展开更多
文摘目的评估人工角膜移植术后患者的视觉相关生活质量及其影响因素。方法采用横断面研究方法收集2004-01/2019-12月在作者医院接受过单眼MICOF人工角膜或BostonⅠ型人工角膜植入术的127例双眼角膜盲患者人口学资料及临床资料,并采用中文版国家眼科研究所视功能问卷-25项(Chinese national eye institute visual function questionnaire-25,CHI-NEI-VFQ-25)评估患者视觉相关生活质量。采用皮尔逊相关分析和斯皮尔曼相关分析术后手术眼BCVA与视觉相关生活质量的相关性。采用多元逐步线性回归分析视觉相关生活质量的影响因素。结果127例患者中,术后随访(4.31±3.16)年,CHI-NEI-VFQ-25综合得分为(44.18±18.40)分。手术至问卷调查时间间隔<2年的患者远距离活动、心理健康、依赖性、驾驶能力得分和综合评分较手术至问卷调查时间间隔≥2年者更低(P均<0.05);接受米赫(MICOF)人工角膜植入患者眼部疼痛、近距离活动、角色困难得分和综合评分较接受波士顿(Boston)Ⅰ型者更高(P均<0.05)。手术眼的术后最佳矫正视力(best corrected visual acuity,BCVA)与CHI-NEI-VFQ-25综合评分(r=-0.775,P<0.001)及除了眼部疼痛(r=0.139,P=0.120)以外的其他子量表得分均呈负相关(P均<0.05)。术后手术眼BCVA和手术至问卷调查时间间隔<2年对CHI-NEI-VFQ-25综合评分具有负向预测作用(β=-21.546,P<0.001;β=-5.698,P=0.029)。结论双眼角膜盲患者的视觉相关生活质量在接受单眼人工角膜手术后有所改善。术后视觉相关生活质量的主要影响因素是手术眼术后视力,但人工角膜植入手术至问卷调查时间间隔是否<2年也会影响视觉相关生活质量。
文摘BACKGROUND Glaucoma is the leading cause of irreversible blindness worldwide,with 60.5 million affected individuals,of whom 11 million are from India.Due to its asymptomatic nature,the disease largely remains underdiagnosed or diagnosed in advanced stages,where little can be done to salvage functional vision.The literature suggests that a lack of knowledge is one of the reasons for its grave consequences.Assessment of awareness is the first step in planning management.Several studies have been conducted in the Indian community,but data from healthcare providers,who play a significant role in educating the masses directly or indirectly,are limited.AIM To identify awareness,knowledge,and attitudes about glaucoma among healthcare workers in a tertiary center in India.METHODS This cross-sectional study was conducted at a tertiary care institute in Eastern India.Data were collected from 423 participants by systematic stratified sampling after Institutional Ethics Committee approval via a pretested,self-designed,semistructured,validated questionnaire.Statistical analyses were performed using the Statistical Package for Social Sciences Software v22.0.Continuous variables are expressed as the means±SD for parametric values and medians with interquartile ranges for nonparametric values.The associations between the variables were studied via multivariate linear and logistic regression.P<0.05 was considered statistically significant.RESULTS Most respondents were 20–30 years old(n=345,81.6%).The knowledge regarding glaucoma was good,and almost 56.3%of the participants gained knowledge from their medical training.The majority were aware that it has a familial predisposition and is secondary to high intraocular pressure,leading to irreversible peripheral vision loss.Only 42%knew about the life-long requirements of treatment.The resident group scored highest on knowledgeand attitude-based questions,whereas the faculty group scored highest on practice-based questions.Although 62%of the nursing staff had good attitude scores,their knowledge and practice scores were lower.The occupation group response difference was statistically significant(P<0.05)for all the knowledge-based questions.CONCLUSION Although the majority of healthcare providers are aware of glaucoma,there is a dearth of knowledge about treatment modalities.Education via seminars and media can improve their knowledge,attitudes,and practices.
