Objective:To explore the therapeutic effect of double-puncture tympanic membrane puncture and tympanic cavity drug injection in patients with acute secretory otitis media.Methods:A total of 84 patients with acute secr...Objective:To explore the therapeutic effect of double-puncture tympanic membrane puncture and tympanic cavity drug injection in patients with acute secretory otitis media.Methods:A total of 84 patients with acute secretory otitis media admitted to our hospital from June 2024 to June 2025 were selected and randomly divided into two groups by drawing lots.The control group(42 cases)was treated with the traditional single-puncture tympanic membrane puncture and tympanic cavity drug injection method,while the observation group(42 cases)was treated with the double-puncture tympanic membrane puncture and tympanic cavity drug injection method.The therapeutic effects of the two groups were compared.Results:The overall treatment response rate,overall complication rate,time to symptom relief,and improvement in hearing threshold in the observation group were all superior to those in the control group,with statistically significant differences(P<0.05).Conclusion:For acute secretory otitis media,the treatment method of double-puncture tympanic membrane puncture and tympanic cavity drug injection demonstrates definite efficacy,significantly reducing the incidence of complications,accelerating symptom relief,and improving hearing function,making it worthy of promotion.展开更多
目的探究腺样体肥大(adenoid hypertrophy,AH)合并分泌性中耳炎(otitis media with effusion,OME)患儿术后复发的影响因素,并构建列线图风险预测模型。方法选取2019-01/2023-04月收治的476例AH合并OME患儿作为研究对象,依据7:3的比例随...目的探究腺样体肥大(adenoid hypertrophy,AH)合并分泌性中耳炎(otitis media with effusion,OME)患儿术后复发的影响因素,并构建列线图风险预测模型。方法选取2019-01/2023-04月收治的476例AH合并OME患儿作为研究对象,依据7:3的比例随机将患儿分为研究组(n=333)及验证组(n=143),依据术后1年的复发情况将研究组患者细分为复发组(n=62)及未复发组(n=271)。收集患者资料,采用多因素Logistic回归分析探讨AH合并OME术后复发的影响因素,采用R软件构建AH合并OME术后复发的列线图风险预测模型,采用受试者工作特征(receiver operating characteristic,ROC)曲线及霍斯默-莱梅肖(Hosmer-Lemeshow,H-L)拟合检验分析构建的风险预测模型的预测效能。结果复发组小于6岁、过敏性鼻炎、腭裂、伴反复呼吸道感染、乳突气化不良、腺样体肥大程度为Ⅲ~Ⅳ度患儿占比高于未复发组(P均<0.05);Logistic回归分析结果显示,年龄、过敏性鼻炎、腭裂、伴反复呼吸道感染、乳突气化不良、腺样体肥大程度是AH合并OME术后复发的影响因素(P<0.05)。H-L拟合检验显示构建的列线图风险预测模型的具有较好的一致性(P>0.05)。结论年龄、过敏性鼻炎、腭裂、伴反复呼吸道感染、乳突气化不良、腺样体肥大程度是AH合并OME术后复发的影响因素,由此构建的列线图风险预测模型具有较好的一致性及区分度。展开更多
文摘Objective:To explore the therapeutic effect of double-puncture tympanic membrane puncture and tympanic cavity drug injection in patients with acute secretory otitis media.Methods:A total of 84 patients with acute secretory otitis media admitted to our hospital from June 2024 to June 2025 were selected and randomly divided into two groups by drawing lots.The control group(42 cases)was treated with the traditional single-puncture tympanic membrane puncture and tympanic cavity drug injection method,while the observation group(42 cases)was treated with the double-puncture tympanic membrane puncture and tympanic cavity drug injection method.The therapeutic effects of the two groups were compared.Results:The overall treatment response rate,overall complication rate,time to symptom relief,and improvement in hearing threshold in the observation group were all superior to those in the control group,with statistically significant differences(P<0.05).Conclusion:For acute secretory otitis media,the treatment method of double-puncture tympanic membrane puncture and tympanic cavity drug injection demonstrates definite efficacy,significantly reducing the incidence of complications,accelerating symptom relief,and improving hearing function,making it worthy of promotion.
文摘目的探究腺样体肥大(adenoid hypertrophy,AH)合并分泌性中耳炎(otitis media with effusion,OME)患儿术后复发的影响因素,并构建列线图风险预测模型。方法选取2019-01/2023-04月收治的476例AH合并OME患儿作为研究对象,依据7:3的比例随机将患儿分为研究组(n=333)及验证组(n=143),依据术后1年的复发情况将研究组患者细分为复发组(n=62)及未复发组(n=271)。收集患者资料,采用多因素Logistic回归分析探讨AH合并OME术后复发的影响因素,采用R软件构建AH合并OME术后复发的列线图风险预测模型,采用受试者工作特征(receiver operating characteristic,ROC)曲线及霍斯默-莱梅肖(Hosmer-Lemeshow,H-L)拟合检验分析构建的风险预测模型的预测效能。结果复发组小于6岁、过敏性鼻炎、腭裂、伴反复呼吸道感染、乳突气化不良、腺样体肥大程度为Ⅲ~Ⅳ度患儿占比高于未复发组(P均<0.05);Logistic回归分析结果显示,年龄、过敏性鼻炎、腭裂、伴反复呼吸道感染、乳突气化不良、腺样体肥大程度是AH合并OME术后复发的影响因素(P<0.05)。H-L拟合检验显示构建的列线图风险预测模型的具有较好的一致性(P>0.05)。结论年龄、过敏性鼻炎、腭裂、伴反复呼吸道感染、乳突气化不良、腺样体肥大程度是AH合并OME术后复发的影响因素,由此构建的列线图风险预测模型具有较好的一致性及区分度。