Objective: To explore the relationship between unexpected damage and clinical character, biological activities and molecular biology. Methods: We treated 76 cases of children wilms tumor from 1995 to 1998. Among them,...Objective: To explore the relationship between unexpected damage and clinical character, biological activities and molecular biology. Methods: We treated 76 cases of children wilms tumor from 1995 to 1998. Among them, 9 cases (11.8%) underwent unexpected damages. We studied and analyzed the clinical characters, clinical pathology, morphology and molecular biology in the 9 cases. Results: Wilms tumor in late stage, blastoma cell type and bad differentiation was likely to be damaged unexpectedly, and the outcome was poor. Conclusions: Mutation of gene is related to the biological activities. It may be a potential and important factor to cause unexpected damage.展开更多
文摘Objective: To explore the relationship between unexpected damage and clinical character, biological activities and molecular biology. Methods: We treated 76 cases of children wilms tumor from 1995 to 1998. Among them, 9 cases (11.8%) underwent unexpected damages. We studied and analyzed the clinical characters, clinical pathology, morphology and molecular biology in the 9 cases. Results: Wilms tumor in late stage, blastoma cell type and bad differentiation was likely to be damaged unexpectedly, and the outcome was poor. Conclusions: Mutation of gene is related to the biological activities. It may be a potential and important factor to cause unexpected damage.
