百日咳是由百日咳杆菌感染引起的一种具有高度传染性的呼吸道疾病,以持续性痉挛性咳嗽为典型表现。近年来出现了“百日咳再现”,部分地区出现百日咳爆发情况。百日咳对儿童普遍易感,尤其是未完成疫苗接种的婴幼儿,部分患儿可能进展为重...百日咳是由百日咳杆菌感染引起的一种具有高度传染性的呼吸道疾病,以持续性痉挛性咳嗽为典型表现。近年来出现了“百日咳再现”,部分地区出现百日咳爆发情况。百日咳对儿童普遍易感,尤其是未完成疫苗接种的婴幼儿,部分患儿可能进展为重症百日咳,出现严重并发症甚至导致死亡。本文将根据近年来儿童重症百日咳相关研究,对儿童重症百日咳的临床特征、治疗措施等进行综述,以提高对重症百日咳的认识。Pertussis is a highly contagious respiratory disease caused by infection with Bordetella pertussis, characterized by a persistent spastic cough. In recent years, there has been a resurgence of pertussis, with outbreaks occurring in some regions. Children are generally susceptible to pertussis, particularly infants and young children who have not completed their vaccination series. Some affected children may progress to severe pertussis, developing serious complications or even succumbing to the disease. This article will review the clinical features and treatment measures of severe pertussis in children based on recent research, aiming to enhance the understanding of severe pertussis.展开更多
文摘百日咳是由百日咳杆菌感染引起的一种具有高度传染性的呼吸道疾病,以持续性痉挛性咳嗽为典型表现。近年来出现了“百日咳再现”,部分地区出现百日咳爆发情况。百日咳对儿童普遍易感,尤其是未完成疫苗接种的婴幼儿,部分患儿可能进展为重症百日咳,出现严重并发症甚至导致死亡。本文将根据近年来儿童重症百日咳相关研究,对儿童重症百日咳的临床特征、治疗措施等进行综述,以提高对重症百日咳的认识。Pertussis is a highly contagious respiratory disease caused by infection with Bordetella pertussis, characterized by a persistent spastic cough. In recent years, there has been a resurgence of pertussis, with outbreaks occurring in some regions. Children are generally susceptible to pertussis, particularly infants and young children who have not completed their vaccination series. Some affected children may progress to severe pertussis, developing serious complications or even succumbing to the disease. This article will review the clinical features and treatment measures of severe pertussis in children based on recent research, aiming to enhance the understanding of severe pertussis.