目的 探讨经尿道钬激光前列腺剜除术(Holmium Laser Enucleation of the Prostate,HoLEP)治疗良性前列腺增生(benign prostatic hyperplasi,BPH)患者的临床疗效、安全性以及性功能的影响。方法 选取2023年1月至2024年6月于浙江中医药大...目的 探讨经尿道钬激光前列腺剜除术(Holmium Laser Enucleation of the Prostate,HoLEP)治疗良性前列腺增生(benign prostatic hyperplasi,BPH)患者的临床疗效、安全性以及性功能的影响。方法 选取2023年1月至2024年6月于浙江中医药大学附属温州市中医院就诊的106例良性前列腺增生患者,随机分为对照组和观察组,对照组接受经尿道前列腺电切术(transurethral resection of the prostate,TURP),观察组实施HoLEP治疗,比较分析两组术后疗效指标(排尿功能)、性功能及并发症变化。结果 组内术后1个月、3个月患者的国际前列腺症状评分(international prostate symptom score,IPSS)、残余尿量较术前相比均显著降低,组间比较观察组低于对照组(P<0.05);组内术后1个月、3个月患者的最大尿流率显著高于术前,且组间比较观察组高于对照组(P<0.05)。术后1个月、3个月比较观察组的国际勃起功能指数评分(简化版)(international index of erectile function-5,IIEF-5)和射精功能评分量表(Chinese index of sexual function for premature ejaculation,CIPE)评分高于对照组(P<0.05)。观察组的包膜穿孔、尿道狭窄、尿失禁和肉眼血尿的发生率低于对照组,观察组的并发症总发生率低于对照组(P<0.05)。结论 Ho LEP治疗良性前列腺增生较TURP临床疗效更显著,患者排尿功能改善更优,性功能影响更小,且安全性更佳。展开更多
目的分析光纤铥激光前列腺剜除术(thulium fiber laser enucleation of the prostate,ThuFLEP)在不同体积良性前列腺增生(benign prostatic hyperplasia,BPH)患者中的应用效果。方法回顾性分析2022年1月至2025年1月在武义县第一人民医...目的分析光纤铥激光前列腺剜除术(thulium fiber laser enucleation of the prostate,ThuFLEP)在不同体积良性前列腺增生(benign prostatic hyperplasia,BPH)患者中的应用效果。方法回顾性分析2022年1月至2025年1月在武义县第一人民医院接受ThuFLEP治疗的BPH患者96例,按术前前列腺体积大小分为小体积组(<40 mL,n=26)、中体积组(40~80 mL,n=40)、大体积组(>80 mL,n=30),对比3组围术期指标、国际前列腺症状评分量表(international prostate symptom score,IPSS)、国际勃起功能指数评分表-5(five-item international index of erectile function,IIEF-5)、生活质量评分(quality of life,QoL)、排尿功能[最大尿流率(Qmax)、残余尿量(PVR)、膀胱顺应性(BC)]、并发症。结果3组粉碎时间、术后尿管留置时间、术后并发症发生率相比,差异无统计学意义(P>0.05);大体积组手术时间、剜除时间、术后住院时间均长于中体积组、小体积组,手术出血量、血红蛋白下降值、剜除前列腺质量均高于中体积组、小体积组(P<0.05),中体积组上述指标分别长于或高于小体积组(P<0.05);3组术前、术后6个月的IPSS、IIEF-5、QoL评分及Qmax相比,差异无统计学意义(P>0.05);3组术后6个月的IPSS、QoL评分及PVR均显著降低,IIEF-5评分及Qmax、BC均显著升高(P<0.05);大体积组术前、术后6个月的PVR均高于中体积组、小体积组,BC均低于中体积组、小体积组(P<0.05),中体积组前、术后6个月的PVR高于小体积组,BC低于小体积组(P<0.05)。结论ThuFLEP在不同体积BPH中均有利于改善患者排尿功能、减轻临床症状、提升性生活质量及生活质量,大体积虽会延长手术时间、增加出血量,但未显著增加并发症发生率。展开更多
Background:Penile augmentation through injectable substances is becoming increasingly common.A growing number of aesthetic clinics are developing penile enlargement procedures using various injectable materials.Althou...Background:Penile augmentation through injectable substances is becoming increasingly common.A growing number of aesthetic clinics are developing penile enlargement procedures using various injectable materials.Although these procedures are now performed in more controlled and medically supervised environments,their long-term outcomes remain poorly understood.The promotion of such medical treatments contributes to an increasing interest among adult males in self-injection as a method to alleviate psychological distress associated with penile size concerns.At the same time,access to injectable substances through unofficial or unregulated sources has become increasingly easy.Tor our knowledge,we report the first documented case of self-injection with Garamycin®(gentamicin)cream,contributing to the literature on the often multidisciplinary management of penile enlargement injections,a field still lacking well-established guidelines.Case Description:This case report describes a young patient who self-injected Garamycin®into the penis for the purpose of enlargement.He presented to our urology department with worsening symptoms,including severe and poorly tolerated pain.His primary request was prompt relief of pain while preserving,as much as possible,the aesthetic appearance and functional integrity of his penis.This case required a multi-stage surgical approach to salvage the penis and preserve both its structural integrity and functional outcome.Conclusions:To our knowledge,this case report documents the first reported instance of Garamycin®injection performed for the purpose of penile enlargement.It provides insight into the clinical course of such penile cream injections,demonstrates that a two-stage scrotal flap can achieve both functional and aesthetic outcomes,and highlights the importance of comprehensive management particularly addressing the traumatic impact of penile deformity secondary to inflammation and/or infection,as well as the body dysmorphic concerns often associated with these cases.展开更多
文摘目的 探讨经尿道钬激光前列腺剜除术(Holmium Laser Enucleation of the Prostate,HoLEP)治疗良性前列腺增生(benign prostatic hyperplasi,BPH)患者的临床疗效、安全性以及性功能的影响。方法 选取2023年1月至2024年6月于浙江中医药大学附属温州市中医院就诊的106例良性前列腺增生患者,随机分为对照组和观察组,对照组接受经尿道前列腺电切术(transurethral resection of the prostate,TURP),观察组实施HoLEP治疗,比较分析两组术后疗效指标(排尿功能)、性功能及并发症变化。结果 组内术后1个月、3个月患者的国际前列腺症状评分(international prostate symptom score,IPSS)、残余尿量较术前相比均显著降低,组间比较观察组低于对照组(P<0.05);组内术后1个月、3个月患者的最大尿流率显著高于术前,且组间比较观察组高于对照组(P<0.05)。术后1个月、3个月比较观察组的国际勃起功能指数评分(简化版)(international index of erectile function-5,IIEF-5)和射精功能评分量表(Chinese index of sexual function for premature ejaculation,CIPE)评分高于对照组(P<0.05)。观察组的包膜穿孔、尿道狭窄、尿失禁和肉眼血尿的发生率低于对照组,观察组的并发症总发生率低于对照组(P<0.05)。结论 Ho LEP治疗良性前列腺增生较TURP临床疗效更显著,患者排尿功能改善更优,性功能影响更小,且安全性更佳。
文摘目的分析光纤铥激光前列腺剜除术(thulium fiber laser enucleation of the prostate,ThuFLEP)在不同体积良性前列腺增生(benign prostatic hyperplasia,BPH)患者中的应用效果。方法回顾性分析2022年1月至2025年1月在武义县第一人民医院接受ThuFLEP治疗的BPH患者96例,按术前前列腺体积大小分为小体积组(<40 mL,n=26)、中体积组(40~80 mL,n=40)、大体积组(>80 mL,n=30),对比3组围术期指标、国际前列腺症状评分量表(international prostate symptom score,IPSS)、国际勃起功能指数评分表-5(five-item international index of erectile function,IIEF-5)、生活质量评分(quality of life,QoL)、排尿功能[最大尿流率(Qmax)、残余尿量(PVR)、膀胱顺应性(BC)]、并发症。结果3组粉碎时间、术后尿管留置时间、术后并发症发生率相比,差异无统计学意义(P>0.05);大体积组手术时间、剜除时间、术后住院时间均长于中体积组、小体积组,手术出血量、血红蛋白下降值、剜除前列腺质量均高于中体积组、小体积组(P<0.05),中体积组上述指标分别长于或高于小体积组(P<0.05);3组术前、术后6个月的IPSS、IIEF-5、QoL评分及Qmax相比,差异无统计学意义(P>0.05);3组术后6个月的IPSS、QoL评分及PVR均显著降低,IIEF-5评分及Qmax、BC均显著升高(P<0.05);大体积组术前、术后6个月的PVR均高于中体积组、小体积组,BC均低于中体积组、小体积组(P<0.05),中体积组前、术后6个月的PVR高于小体积组,BC低于小体积组(P<0.05)。结论ThuFLEP在不同体积BPH中均有利于改善患者排尿功能、减轻临床症状、提升性生活质量及生活质量,大体积虽会延长手术时间、增加出血量,但未显著增加并发症发生率。
文摘Background:Penile augmentation through injectable substances is becoming increasingly common.A growing number of aesthetic clinics are developing penile enlargement procedures using various injectable materials.Although these procedures are now performed in more controlled and medically supervised environments,their long-term outcomes remain poorly understood.The promotion of such medical treatments contributes to an increasing interest among adult males in self-injection as a method to alleviate psychological distress associated with penile size concerns.At the same time,access to injectable substances through unofficial or unregulated sources has become increasingly easy.Tor our knowledge,we report the first documented case of self-injection with Garamycin®(gentamicin)cream,contributing to the literature on the often multidisciplinary management of penile enlargement injections,a field still lacking well-established guidelines.Case Description:This case report describes a young patient who self-injected Garamycin®into the penis for the purpose of enlargement.He presented to our urology department with worsening symptoms,including severe and poorly tolerated pain.His primary request was prompt relief of pain while preserving,as much as possible,the aesthetic appearance and functional integrity of his penis.This case required a multi-stage surgical approach to salvage the penis and preserve both its structural integrity and functional outcome.Conclusions:To our knowledge,this case report documents the first reported instance of Garamycin®injection performed for the purpose of penile enlargement.It provides insight into the clinical course of such penile cream injections,demonstrates that a two-stage scrotal flap can achieve both functional and aesthetic outcomes,and highlights the importance of comprehensive management particularly addressing the traumatic impact of penile deformity secondary to inflammation and/or infection,as well as the body dysmorphic concerns often associated with these cases.
