上海市胸科医院胸外科食管功能检测已有30多年历史,是我国胸外科唯一拥有食管功能检测的科室。历经3代食管功能检测机器的更新换代,食管腔内24 h pH/阻抗监测可以协助诊断、治疗与之相关的食管良、恶性疾病。得益于食管功能检测,除了常...上海市胸科医院胸外科食管功能检测已有30多年历史,是我国胸外科唯一拥有食管功能检测的科室。历经3代食管功能检测机器的更新换代,食管腔内24 h pH/阻抗监测可以协助诊断、治疗与之相关的食管良、恶性疾病。得益于食管功能检测,除了常规的各类内镜下抗反流手术,上海市胸科医院近年来在国内率先开展系列针对食管良性疾病的工作及研究,如磁力环、双镜联合和抗反流内镜下新技术等,对疑因胃食管反流引起的间质性肺炎、肺纤维化患者行高分辨率食管测压及24 h pH/阻抗监测,评估患者胃食管反流与间质性肺炎、肺纤维化之间的相关性,为临床提供不同治疗依据甚至外科手术干预。美国使用Bravo胶囊较多,其对于传统测酸测压有明显优势。我们大力呼吁在这一领域开展产学研结合工作,开发具有自主知识产权的“本土制造”。展开更多
Gastroesophageal reflux disease(GERD)poses a substantial global health challenge,with prevalence rates exhibiting geographical variation.Despite its widespread recognition,the exact prevalence and associated risk fact...Gastroesophageal reflux disease(GERD)poses a substantial global health challenge,with prevalence rates exhibiting geographical variation.Despite its widespread recognition,the exact prevalence and associated risk factors remain elusive.This article comprehensively analyzed the global burden of GERD,shedding light on its risk factors,underlying pathophysiological mechanisms,current diagnostic modalities,evolving management strategies tailored to diverse patient profiles,and complex determinants contributing to treatment failures.A deeper comprehension of GERD is achieved by dissecting these intricate facets,paving the way for enhanced clinical management and improved patient outcomes.展开更多
文摘上海市胸科医院胸外科食管功能检测已有30多年历史,是我国胸外科唯一拥有食管功能检测的科室。历经3代食管功能检测机器的更新换代,食管腔内24 h pH/阻抗监测可以协助诊断、治疗与之相关的食管良、恶性疾病。得益于食管功能检测,除了常规的各类内镜下抗反流手术,上海市胸科医院近年来在国内率先开展系列针对食管良性疾病的工作及研究,如磁力环、双镜联合和抗反流内镜下新技术等,对疑因胃食管反流引起的间质性肺炎、肺纤维化患者行高分辨率食管测压及24 h pH/阻抗监测,评估患者胃食管反流与间质性肺炎、肺纤维化之间的相关性,为临床提供不同治疗依据甚至外科手术干预。美国使用Bravo胶囊较多,其对于传统测酸测压有明显优势。我们大力呼吁在这一领域开展产学研结合工作,开发具有自主知识产权的“本土制造”。
文摘Gastroesophageal reflux disease(GERD)poses a substantial global health challenge,with prevalence rates exhibiting geographical variation.Despite its widespread recognition,the exact prevalence and associated risk factors remain elusive.This article comprehensively analyzed the global burden of GERD,shedding light on its risk factors,underlying pathophysiological mechanisms,current diagnostic modalities,evolving management strategies tailored to diverse patient profiles,and complex determinants contributing to treatment failures.A deeper comprehension of GERD is achieved by dissecting these intricate facets,paving the way for enhanced clinical management and improved patient outcomes.