BACKGROUND Coronavirus disease 2019(COVID-19)pneumonia with severe septic shock and acute respiratory distress syndrome(ARDS)are critical illnesses for patients following transplant.Intravenous immunoglobulin(IVIG)pla...BACKGROUND Coronavirus disease 2019(COVID-19)pneumonia with severe septic shock and acute respiratory distress syndrome(ARDS)are critical illnesses for patients following transplant.Intravenous immunoglobulin(IVIG)plays a role in both immune support and inflammation control,especially in immunocompromised patients.This case report describes the first successful experience using IVIG and pulse steroids to manage this critical condition following lung transplantation.CASE SUMMARY A 65-year-old male patient reported a history of chronic obstructive pulmonary disease and poor lung function and received bilateral sequential lung transplantations.Postoperatively,he developed COVID-19 pneumonia,severe septic shock,and ARDS.He recovered from this critical condition after empirical antibiotics administration and veno-venous extracorporeal membrane oxygenation,in addition to IVIG and pulse steroids.CONCLUSION IVIG is a valuable adjunct in managing severe sepsis in lung transplant recipients after COVID-19 infection.We aim,for the first time,to report the success of such a management approach for COVID-19 ARDS and sepsis in the post-lung transplant setting.With further investigations,this is a starting point for wider analysis of such an approach in this setting and consequently helps guide clinical practice for such a challenging patient population moving forward.展开更多
目的:探讨岩下窦采样在cush ing综合征鉴别诊断中的作用。方法:对32例确诊为cush ing综合征的患者行M R I和IPSS检查,分别计算他们的阳性率,并比较他们的检查价值。结果:M R I检查阳性率为61.54%,IPSS检查阳性率为93.75%,两者比较诊断...目的:探讨岩下窦采样在cush ing综合征鉴别诊断中的作用。方法:对32例确诊为cush ing综合征的患者行M R I和IPSS检查,分别计算他们的阳性率,并比较他们的检查价值。结果:M R I检查阳性率为61.54%,IPSS检查阳性率为93.75%,两者比较诊断准确率差异性明显。结论:IPSS在cush ing综合征鉴别诊断中是一种可行的、准确率高的检查方法。展开更多
文摘BACKGROUND Coronavirus disease 2019(COVID-19)pneumonia with severe septic shock and acute respiratory distress syndrome(ARDS)are critical illnesses for patients following transplant.Intravenous immunoglobulin(IVIG)plays a role in both immune support and inflammation control,especially in immunocompromised patients.This case report describes the first successful experience using IVIG and pulse steroids to manage this critical condition following lung transplantation.CASE SUMMARY A 65-year-old male patient reported a history of chronic obstructive pulmonary disease and poor lung function and received bilateral sequential lung transplantations.Postoperatively,he developed COVID-19 pneumonia,severe septic shock,and ARDS.He recovered from this critical condition after empirical antibiotics administration and veno-venous extracorporeal membrane oxygenation,in addition to IVIG and pulse steroids.CONCLUSION IVIG is a valuable adjunct in managing severe sepsis in lung transplant recipients after COVID-19 infection.We aim,for the first time,to report the success of such a management approach for COVID-19 ARDS and sepsis in the post-lung transplant setting.With further investigations,this is a starting point for wider analysis of such an approach in this setting and consequently helps guide clinical practice for such a challenging patient population moving forward.
文摘目的:探讨岩下窦采样在cush ing综合征鉴别诊断中的作用。方法:对32例确诊为cush ing综合征的患者行M R I和IPSS检查,分别计算他们的阳性率,并比较他们的检查价值。结果:M R I检查阳性率为61.54%,IPSS检查阳性率为93.75%,两者比较诊断准确率差异性明显。结论:IPSS在cush ing综合征鉴别诊断中是一种可行的、准确率高的检查方法。
