目的:研究青少年近视患者就医决策延迟与家庭动力学关系。方法:本研究为前瞻性研究,选取2023年9月至2024年8月沈阳何氏眼科医院就诊的416例青少年近视患者的主要照顾者。采用问卷调查量表收集青少年近视患者及其主要照顾者临床资料,采...目的:研究青少年近视患者就医决策延迟与家庭动力学关系。方法:本研究为前瞻性研究,选取2023年9月至2024年8月沈阳何氏眼科医院就诊的416例青少年近视患者的主要照顾者。采用问卷调查量表收集青少年近视患者及其主要照顾者临床资料,采用就医决策障碍感知量表中文版(patient barriers to healthcare seeking decision in Chinese patients,PBHSD-C)评估青少年近视患者主要照顾者的就医决策延迟情况,根据是否就医决策延迟分为就医决策延迟组和就医决策未延迟组。采用家庭动力学量表第2版(family dynamics measure Ⅱ,FDM Ⅱ)评估青少年近视患者的家庭动力学情况。采用Pearson相关性分析青少年近视患者就医决策延迟与家庭动力学的相关性。采用单因素和多因素Logistic回归分析青少年近视患者就医决策延迟的影响因素。结果:416例青少年近视患者的主要照顾者PBHSD-C评分为(32.59±8.41)分,根据是否就医决策延迟分为就医决策延迟组(PBHSD-C>30分,n=257)和就医决策未延迟组(PBHSD-C≤30分,n=159)。就医决策延迟组的独立性对缠结、相互依存对孤立、灵活对僵化、稳定对瓦解、沟通清楚对沟通模糊、角色互补对角色冲突评分低于就医决策未延迟组(P<0.05)。Pearson相关性分析结果显示,PBHSD-C评分与独立性对缠结、相互依存对孤立、灵活对僵化、稳定对瓦解、沟通清楚对沟通模糊、角色互补对角色冲突评分呈负相关(P<0.05)。单因素分析结果显示,就医决策与文化程度、工作情况、家庭月收入情况、支付方式、居住地、家庭关系、近视相关知识了解程度、是否隐瞒近视症状有关(P<0.05)。多因素Logistc分析结果显示,文化程度小学及其以下、家庭月收入情况<3000元/月、居住地农村、不了解近视相关知识、隐瞒近视症状是青少年近视患者就医决策延迟的影响因素(P<0.05)。结论:青少年近视患者就医决策延迟与家庭动力学相关,同时文化程度、家庭月收入情况、居住地、近视相关知识了解程度、是否隐瞒近视症状是青少年近视患者就医决策延迟的影响因素。展开更多
The visual cortex is an essential part of the brain for processing visual information.It exhibits structural and functional plasticity,which is crucial for adapting to complex visual environments.The quintessential ma...The visual cortex is an essential part of the brain for processing visual information.It exhibits structural and functional plasticity,which is crucial for adapting to complex visual environments.The quintessential manifestation of visual cortical plasticity is ocular dominance plasticity during the critical period,which involves numerous cellular and molecular events.While previous studies have emphasized the role of visual cortical neurons and their associated functional molecules in visual plasticity,recent findings have revealed that structural factors such as the extracellular matrix and glia are also involved.Investigating how these molecules interact to form a complex network that facilitates plasticity in the visual cortex is crucial to our understanding of the development of the visual system and the advancement of therapeutic strategies for visual disorders like amblyopia.展开更多
文摘目的:研究青少年近视患者就医决策延迟与家庭动力学关系。方法:本研究为前瞻性研究,选取2023年9月至2024年8月沈阳何氏眼科医院就诊的416例青少年近视患者的主要照顾者。采用问卷调查量表收集青少年近视患者及其主要照顾者临床资料,采用就医决策障碍感知量表中文版(patient barriers to healthcare seeking decision in Chinese patients,PBHSD-C)评估青少年近视患者主要照顾者的就医决策延迟情况,根据是否就医决策延迟分为就医决策延迟组和就医决策未延迟组。采用家庭动力学量表第2版(family dynamics measure Ⅱ,FDM Ⅱ)评估青少年近视患者的家庭动力学情况。采用Pearson相关性分析青少年近视患者就医决策延迟与家庭动力学的相关性。采用单因素和多因素Logistic回归分析青少年近视患者就医决策延迟的影响因素。结果:416例青少年近视患者的主要照顾者PBHSD-C评分为(32.59±8.41)分,根据是否就医决策延迟分为就医决策延迟组(PBHSD-C>30分,n=257)和就医决策未延迟组(PBHSD-C≤30分,n=159)。就医决策延迟组的独立性对缠结、相互依存对孤立、灵活对僵化、稳定对瓦解、沟通清楚对沟通模糊、角色互补对角色冲突评分低于就医决策未延迟组(P<0.05)。Pearson相关性分析结果显示,PBHSD-C评分与独立性对缠结、相互依存对孤立、灵活对僵化、稳定对瓦解、沟通清楚对沟通模糊、角色互补对角色冲突评分呈负相关(P<0.05)。单因素分析结果显示,就医决策与文化程度、工作情况、家庭月收入情况、支付方式、居住地、家庭关系、近视相关知识了解程度、是否隐瞒近视症状有关(P<0.05)。多因素Logistc分析结果显示,文化程度小学及其以下、家庭月收入情况<3000元/月、居住地农村、不了解近视相关知识、隐瞒近视症状是青少年近视患者就医决策延迟的影响因素(P<0.05)。结论:青少年近视患者就医决策延迟与家庭动力学相关,同时文化程度、家庭月收入情况、居住地、近视相关知识了解程度、是否隐瞒近视症状是青少年近视患者就医决策延迟的影响因素。
基金supported by the National Natural Science Foundation of China(81770956,81371049,32471055 and 82171090)Project of Tianjin 131 Innovative Talent Team(201936)+4 种基金the Science and Technology Planning Project of Tianjin(21JCYBJC00780)the Science and Technology Fund for Health of Tianjin(TJWJ2023ZD008)Shanghai Municipal Science and Technology Major Project(2018SHZDZX01)ZJLab,Shanghai Center for Brain Science and Brain-Inspired Technology,the Lingang Laboratory(LG-QS-202203-12)Tianjin Key Medical Discipline(Specialty)Construction Project(TJYXZDXK‑016A).
文摘The visual cortex is an essential part of the brain for processing visual information.It exhibits structural and functional plasticity,which is crucial for adapting to complex visual environments.The quintessential manifestation of visual cortical plasticity is ocular dominance plasticity during the critical period,which involves numerous cellular and molecular events.While previous studies have emphasized the role of visual cortical neurons and their associated functional molecules in visual plasticity,recent findings have revealed that structural factors such as the extracellular matrix and glia are also involved.Investigating how these molecules interact to form a complex network that facilitates plasticity in the visual cortex is crucial to our understanding of the development of the visual system and the advancement of therapeutic strategies for visual disorders like amblyopia.
