Objective： To observe the clinical effect of point application using Chinese herbal medicine for chronic cough in children. Methods： A total of 200 children with chronic cough were randomly allocated into an observ...Objective： To observe the clinical effect of point application using Chinese herbal medicine for chronic cough in children. Methods： A total of 200 children with chronic cough were randomly allocated into an observation group and a control group, 100 cases in each group. Conventional Western medication was used for cases in the control group, whereas conventional Western medication plus point application using Chinese herbal medicine were used for cases in the observation group. Changes of indexes including eosinophils （EOS）, peak expiratory flow （PEF） and forced expiratory volume in one second （FEV1） were observed before and after treatment. In addition, the clinical effects were compared between the two groups. Results： After treatment, coughs in children were alleviated in both groups; however, it took a shorter period of time for cough alleviation in the observation group than that in the control group （P^0.01）. On the 28th day of treatment, the EOS, PEF and FEVl were improved in both groups （P〈0.01）, and the improvements were more significant in the observation group （P〈0.05）. Additionally, the frequencies of cough variant asthma attacks were decreased in both groups, but a better effect in the observation group than the control group. Conclusion： Complementary point application using Chinese herbal medicine could substantially improve the clinical effect, alleviate coughs and benefit lung functions.展开更多
基金supported by Xu’s Pediatric Clinical Experience Inheritance Base (No. ZYSNXD-CC-HPGCJD-005)Emerging Frontier Technology Joint Research Program of Shanghai Municipal Hospitals (No. SHDC12012410)+3 种基金Domestic Visiting Scholar Program for Young Teachers at Shanghai Colleges and UniversitiesTang Wei-yong Work Room of Shanghai Three-year Action Plan of Traditional Chinese Medicine (No. ZYSNXD-CC-MZY001)Cheng Jia-zheng Work Room of Three-year Action Plan of Traditional Chinese Medicine (No. ZYSNXD-CC-MZY002)the Third Group Construction Project of Clinical Advantages Specialized Subject of Traditional Chinese Medicine in Shanghai (No. ZYSNXD-YL-YSZK006)
文摘Objective： To observe the clinical effect of point application using Chinese herbal medicine for chronic cough in children. Methods： A total of 200 children with chronic cough were randomly allocated into an observation group and a control group, 100 cases in each group. Conventional Western medication was used for cases in the control group, whereas conventional Western medication plus point application using Chinese herbal medicine were used for cases in the observation group. Changes of indexes including eosinophils （EOS）, peak expiratory flow （PEF） and forced expiratory volume in one second （FEV1） were observed before and after treatment. In addition, the clinical effects were compared between the two groups. Results： After treatment, coughs in children were alleviated in both groups; however, it took a shorter period of time for cough alleviation in the observation group than that in the control group （P^0.01）. On the 28th day of treatment, the EOS, PEF and FEVl were improved in both groups （P〈0.01）, and the improvements were more significant in the observation group （P〈0.05）. Additionally, the frequencies of cough variant asthma attacks were decreased in both groups, but a better effect in the observation group than the control group. Conclusion： Complementary point application using Chinese herbal medicine could substantially improve the clinical effect, alleviate coughs and benefit lung functions.
