目的观察腰椎间盘突出症(lumbar disc herniation,LDH)患者接受电火针联合身痛逐瘀汤治疗的临床疗效。方法选取2023年7—12月在大连康复疗养中心就诊的48例LDH患者为研究对象,随机分为2组,观察组(24例)予电火针联合身痛逐瘀汤治疗,对照...目的观察腰椎间盘突出症(lumbar disc herniation,LDH)患者接受电火针联合身痛逐瘀汤治疗的临床疗效。方法选取2023年7—12月在大连康复疗养中心就诊的48例LDH患者为研究对象,随机分为2组,观察组(24例)予电火针联合身痛逐瘀汤治疗,对照组(24例)予身痛逐瘀汤治疗。比较2组患者症状消失时间、生存质量评分(36 Item Short Form Survey Instrument,SF-36)、视觉模拟评分(Visual Analogue Scale,VAS)和腰椎功能功能评分(Japanese Orthopaedic Association Scores,JOA)。结果治疗5周后,观察组腰部、腿部区域疼痛、酸楚等症状消失时间均较对照组短(t=7.530、7.988、11.735、12.890,P均<0.001);SF-36评分各维度较对照组高(t=12.493、12.357、12.531、12.034,P均<0.001);治疗1、3、5周等时段,观察组VAS评分均较对照组低(P=0.001、<0.001、=0.001);JOA评分均较对照组高(P=0.015、<0.001、<0.001)。结论电火针联合身痛逐瘀汤治疗腰椎间盘突出症,相较于单独应用身痛逐瘀汤治疗优势更明显,可有效提高LDH患者生存质量,恢复患者腰椎功能,减轻腰部疼痛等不适症状,具备临床推广价值。展开更多
Chronic pain, especially the chronic neuropathic pain syndrome characterized by long duration, slow recovery and difficulty to control in clinic practice makes it more serious physically and psychologically. Nowadays,...Chronic pain, especially the chronic neuropathic pain syndrome characterized by long duration, slow recovery and difficulty to control in clinic practice makes it more serious physically and psychologically. Nowadays, the field of chro nic neuropathic pain has been grasping more and more attention. The present stud y aims at investigating the optimal interval parameter of the electroacupunctur e (EA) treatment. L 5/L 6 nerve ligation model was used to assess the effect o f EA on neuropathic pain. Mechanical allodynia was assessed by 50% paw withdrawal t hreshold and cold induced ongoing pain was detected by the number of paw lifts within 5 minutes when free rat was put on to 5±1 ℃ cold plate. Han’s Acupoint Nerve Stimulator (HANS) was connected to needles inserted into acupo ints "Jiaji"(EX B 2/L 5) and "Weizhong" (BL 40) on both sides. Other parame ters were: intensity of 0.5～ 1 mA, 1～2 mA , ten minutes each; frequency of 2 H z; and 0.6 ms in pulse width. Different interval parameter was Q 1 day (one tr eatment/day), Q 2 day, Q 3 day and Q 4 day. Results: Optimal interval pla ys a critical r ole for the analgesic effect of electroacupuncture. The interval of Q 1 day ha s a declining analgesic effect or even not any effect. The other 3 groups have accumulative effect and long lasting analgesic effect (24 hours for mechanical allodynia and 1 week for cold induced ongoing pain). Compared with the control, there is a significant difference (P<0.01 or 0.001). Among these 4 in tervals, Q 3 day group is the best. Longer lasting analgesic effect following this interval choice (48 hours for mechanical allodynia and 10 days for cold i nduced ongoing pain). Amongst the 4 interval parameters, Q 3 day group has don e better effect than the others(P<0.01 or 0.001). The results indicate that one EA treatment every 3 days is the optimal interval. And it may have som ething to do with the clinical practice.展开更多
文摘目的观察腰椎间盘突出症(lumbar disc herniation,LDH)患者接受电火针联合身痛逐瘀汤治疗的临床疗效。方法选取2023年7—12月在大连康复疗养中心就诊的48例LDH患者为研究对象,随机分为2组,观察组(24例)予电火针联合身痛逐瘀汤治疗,对照组(24例)予身痛逐瘀汤治疗。比较2组患者症状消失时间、生存质量评分(36 Item Short Form Survey Instrument,SF-36)、视觉模拟评分(Visual Analogue Scale,VAS)和腰椎功能功能评分(Japanese Orthopaedic Association Scores,JOA)。结果治疗5周后,观察组腰部、腿部区域疼痛、酸楚等症状消失时间均较对照组短(t=7.530、7.988、11.735、12.890,P均<0.001);SF-36评分各维度较对照组高(t=12.493、12.357、12.531、12.034,P均<0.001);治疗1、3、5周等时段,观察组VAS评分均较对照组低(P=0.001、<0.001、=0.001);JOA评分均较对照组高(P=0.015、<0.001、<0.001)。结论电火针联合身痛逐瘀汤治疗腰椎间盘突出症,相较于单独应用身痛逐瘀汤治疗优势更明显,可有效提高LDH患者生存质量,恢复患者腰椎功能,减轻腰部疼痛等不适症状,具备临床推广价值。
文摘Chronic pain, especially the chronic neuropathic pain syndrome characterized by long duration, slow recovery and difficulty to control in clinic practice makes it more serious physically and psychologically. Nowadays, the field of chro nic neuropathic pain has been grasping more and more attention. The present stud y aims at investigating the optimal interval parameter of the electroacupunctur e (EA) treatment. L 5/L 6 nerve ligation model was used to assess the effect o f EA on neuropathic pain. Mechanical allodynia was assessed by 50% paw withdrawal t hreshold and cold induced ongoing pain was detected by the number of paw lifts within 5 minutes when free rat was put on to 5±1 ℃ cold plate. Han’s Acupoint Nerve Stimulator (HANS) was connected to needles inserted into acupo ints "Jiaji"(EX B 2/L 5) and "Weizhong" (BL 40) on both sides. Other parame ters were: intensity of 0.5～ 1 mA, 1～2 mA , ten minutes each; frequency of 2 H z; and 0.6 ms in pulse width. Different interval parameter was Q 1 day (one tr eatment/day), Q 2 day, Q 3 day and Q 4 day. Results: Optimal interval pla ys a critical r ole for the analgesic effect of electroacupuncture. The interval of Q 1 day ha s a declining analgesic effect or even not any effect. The other 3 groups have accumulative effect and long lasting analgesic effect (24 hours for mechanical allodynia and 1 week for cold induced ongoing pain). Compared with the control, there is a significant difference (P<0.01 or 0.001). Among these 4 in tervals, Q 3 day group is the best. Longer lasting analgesic effect following this interval choice (48 hours for mechanical allodynia and 10 days for cold i nduced ongoing pain). Amongst the 4 interval parameters, Q 3 day group has don e better effect than the others(P<0.01 or 0.001). The results indicate that one EA treatment every 3 days is the optimal interval. And it may have som ething to do with the clinical practice.
