In recent years,new technologies have enabled a steady stream of novel theoretical approaches to understanding the mechanisms of disease occurrence and development.The emergence of these new technologies has provided ...In recent years,new technologies have enabled a steady stream of novel theoretical approaches to understanding the mechanisms of disease occurrence and development.The emergence of these new technologies has provided the pharmaceutical industry with a huge amount of data that can be utilized,such as brain-computer inter-faces,artificial intelligence(AI)doctors,wearable medical testing de-vices,etc.展开更多
In order to understand the fundamental questions of the biology of life and to duplicate the pathogenesis of human diseases, animal models using different experimental animals, such as rodents, Drosophila, Caenorhabdi...In order to understand the fundamental questions of the biology of life and to duplicate the pathogenesis of human diseases, animal models using different experimental animals, such as rodents, Drosophila, Caenorhabditis elegans, and zebrafish, have been established and used widely for many decades. The controllability of environmental conditions, the high reproducibility, the ease of scale and the comparability of results, as well as the ability to use different standards for ethical protocols, all make an animal model the ideal tool for carrying out studies on human diseases and the development of novel pharmaceuticals and new therapies （Xue et al., 2014）. An ideal animal model should reflect the complete spectra of a specific human disease, with similar features on the following key issues： （1） genetic basis; （2） anatomy and physiology; （3） pathological response（s） and underlying mechanism（s）; （4） phenotypic endpoints as clinical studies; （5） responsiveness to known drugs with clinical efficacy; and （6） prediction of clinical efficacy （McGonigle and Ruggeri, 2014）.展开更多
WPA-China was established in 1991 as a chapter of World Pheasants Association (WPA)-International with Prof. Guangmei ZHENG now as its president. WPA-China has about 100 members from all over the country, mostly resea...WPA-China was established in 1991 as a chapter of World Pheasants Association (WPA)-International with Prof. Guangmei ZHENG now as its president. WPA-China has about 100 members from all over the country, mostly researchers from universities,展开更多
文摘In recent years,new technologies have enabled a steady stream of novel theoretical approaches to understanding the mechanisms of disease occurrence and development.The emergence of these new technologies has provided the pharmaceutical industry with a huge amount of data that can be utilized,such as brain-computer inter-faces,artificial intelligence(AI)doctors,wearable medical testing de-vices,etc.
文摘In order to understand the fundamental questions of the biology of life and to duplicate the pathogenesis of human diseases, animal models using different experimental animals, such as rodents, Drosophila, Caenorhabditis elegans, and zebrafish, have been established and used widely for many decades. The controllability of environmental conditions, the high reproducibility, the ease of scale and the comparability of results, as well as the ability to use different standards for ethical protocols, all make an animal model the ideal tool for carrying out studies on human diseases and the development of novel pharmaceuticals and new therapies （Xue et al., 2014）. An ideal animal model should reflect the complete spectra of a specific human disease, with similar features on the following key issues： （1） genetic basis; （2） anatomy and physiology; （3） pathological response（s） and underlying mechanism（s）; （4） phenotypic endpoints as clinical studies; （5） responsiveness to known drugs with clinical efficacy; and （6） prediction of clinical efficacy （McGonigle and Ruggeri, 2014）.
文摘WPA-China was established in 1991 as a chapter of World Pheasants Association (WPA)-International with Prof. Guangmei ZHENG now as its president. WPA-China has about 100 members from all over the country, mostly researchers from universities,
