A new ruthenium（Ⅱ） complex,[Ru（bpy）2bdpq](ClO4)2,where bpy=2,2′-bipyridine,（bdpq=2-（benzoxazol-2-yl）-dipyrido） [2,3-f: 2′,3′-h]quinoxaline,was synthesized and characterized by IR,（）1H NMR,MALDI-TOF MS,an...A new ruthenium（Ⅱ） complex,[Ru（bpy）2bdpq](ClO4)2,where bpy=2,2′-bipyridine,（bdpq=2-（benzoxazol-2-yl）-dipyrido） [2,3-f: 2′,3′-h]quinoxaline,was synthesized and characterized by IR,（）1H NMR,MALDI-TOF MS,and elemental analysis.The electronic absorption and emission spectral titrations with calf thymus DNA,steady-state emission quenching by [Fe（CN）6]4-,and viscosity measurements were carried out to study the binding of [Ru（bpy）2bdpq](ClO4)2 with the DNA.The results indicate that the（Ru（Ⅱ）） complex acts as a DNA intercalator with a binding constant of（1.9±0.1）×106 L/mol at 50 mmol/L NaCl,and can serve as a good "DNA molecular light switches" with a luminescence enhancement factor of 180.展开更多
The alanine platinum complex are synthesized by potassium terachloroplatinate(K2PtCl4) with alanine in aqueous solution.The features of alanine platinum complex are marked with TLC,DSC,IR spectrum,elemental analysis a...The alanine platinum complex are synthesized by potassium terachloroplatinate(K2PtCl4) with alanine in aqueous solution.The features of alanine platinum complex are marked with TLC,DSC,IR spectrum,elemental analysis and anticancer activity external body test.The results indicat that the platinum complex have some anticancer activity.展开更多
文摘A new ruthenium（Ⅱ） complex,[Ru（bpy）2bdpq](ClO4)2,where bpy=2,2′-bipyridine,（bdpq=2-（benzoxazol-2-yl）-dipyrido） [2,3-f: 2′,3′-h]quinoxaline,was synthesized and characterized by IR,（）1H NMR,MALDI-TOF MS,and elemental analysis.The electronic absorption and emission spectral titrations with calf thymus DNA,steady-state emission quenching by [Fe（CN）6]4-,and viscosity measurements were carried out to study the binding of [Ru（bpy）2bdpq](ClO4)2 with the DNA.The results indicate that the（Ru（Ⅱ）） complex acts as a DNA intercalator with a binding constant of（1.9±0.1）×106 L/mol at 50 mmol/L NaCl,and can serve as a good "DNA molecular light switches" with a luminescence enhancement factor of 180.
文摘The alanine platinum complex are synthesized by potassium terachloroplatinate(K2PtCl4) with alanine in aqueous solution.The features of alanine platinum complex are marked with TLC,DSC,IR spectrum,elemental analysis and anticancer activity external body test.The results indicat that the platinum complex have some anticancer activity.
