The 5-fluorouracil-1-acetic acid (5FuAA) and its Cu! complex (5FuAACu) were synthesized and the date for the crystal complex was obtained. The interaction of 5-fluorouracil-1-acetic acid (5FuAA) and its Cu! complex (5...The 5-fluorouracil-1-acetic acid (5FuAA) and its Cu! complex (5FuAACu) were synthesized and the date for the crystal complex was obtained. The interaction of 5-fluorouracil-1-acetic acid (5FuAA) and its Cu! complex (5FuAACu) with DNA was also investigated by using spectral, viscometric, electrochemical and agarose gel electrophoresis methods. The results of interaction with DNA suggest that both 5FuAA and 5FuAACu can bind to DNA in a static electricity attraction mode. But the attraction of 5FuAACu is greater than that of 5FuAA.展开更多
A novel coordination polymer, [Cu(m-BDOA)(bipy)·H2O]n (m-BDOA2-=benzene-1,3-dioxyacetate), was synthesized and characterized by elemental analysis, IR spectra, X-ray single crystal structure analysis. Crystallogr...A novel coordination polymer, [Cu(m-BDOA)(bipy)·H2O]n (m-BDOA2-=benzene-1,3-dioxyacetate), was synthesized and characterized by elemental analysis, IR spectra, X-ray single crystal structure analysis. Crystallographic data are as follows: orthorhombic, space group Pna21, a=1.606 9(3) nm, b=1.685 9(3) nm, c=0.699 7(1) nm, V=1.8955(7) nm3, Z=4, Dc=1.619 g·cm-3, -ligand, two nitrogen atoms of 2,2′-bipy ligand and one coordinated water, there is a distorted square pyramidal environment. Two copper atoms are bridged by m-BDOA2-ligand, forming a one-dimensional chain along a axis. The adjacent distance of Cu...Cu atoms is 0.877 3 nm. The crystal network was formed by the intermolecular hydrogen bond and π-packing interactions.展开更多
文摘The 5-fluorouracil-1-acetic acid (5FuAA) and its Cu! complex (5FuAACu) were synthesized and the date for the crystal complex was obtained. The interaction of 5-fluorouracil-1-acetic acid (5FuAA) and its Cu! complex (5FuAACu) with DNA was also investigated by using spectral, viscometric, electrochemical and agarose gel electrophoresis methods. The results of interaction with DNA suggest that both 5FuAA and 5FuAACu can bind to DNA in a static electricity attraction mode. But the attraction of 5FuAACu is greater than that of 5FuAA.
文摘A novel coordination polymer, [Cu(m-BDOA)(bipy)·H2O]n (m-BDOA2-=benzene-1,3-dioxyacetate), was synthesized and characterized by elemental analysis, IR spectra, X-ray single crystal structure analysis. Crystallographic data are as follows: orthorhombic, space group Pna21, a=1.606 9(3) nm, b=1.685 9(3) nm, c=0.699 7(1) nm, V=1.8955(7) nm3, Z=4, Dc=1.619 g·cm-3, -ligand, two nitrogen atoms of 2,2′-bipy ligand and one coordinated water, there is a distorted square pyramidal environment. Two copper atoms are bridged by m-BDOA2-ligand, forming a one-dimensional chain along a axis. The adjacent distance of Cu...Cu atoms is 0.877 3 nm. The crystal network was formed by the intermolecular hydrogen bond and π-packing interactions.
