以甲酸和氢氧化钾为原料,不外加任何溶剂一步合成二甲酸钾。通过单因素实验,考察了原料配比、反应温度和反应时间对产品质量与收率的影响。采用正交实验进一步优化了合成工艺,确定了最佳工艺条件:n(HCOOH)/n(KOH)=2.2、反应温度70℃、...以甲酸和氢氧化钾为原料,不外加任何溶剂一步合成二甲酸钾。通过单因素实验,考察了原料配比、反应温度和反应时间对产品质量与收率的影响。采用正交实验进一步优化了合成工艺,确定了最佳工艺条件:n(HCOOH)/n(KOH)=2.2、反应温度70℃、反应时间30 m in,在该条件下,二甲酸钾产品收率达98%以上。所得产品经红外光谱分析及熔点测定,其结果与文献报道一致。反应过程绿色化,有很好的原子经济性。展开更多
The crystal of [Cu(L-His) (Phen)]·2ClO4·H2O was synthesized and characterized by element analysis, molar conductivity, UV, IR and X-ray single crystal structure. The crystal belongs to monoclinic system, spa...The crystal of [Cu(L-His) (Phen)]·2ClO4·H2O was synthesized and characterized by element analysis, molar conductivity, UV, IR and X-ray single crystal structure. The crystal belongs to monoclinic system, space group P21, with a=1. 222 7(2) nm, b=0. 714 5(14) nm, c=1. 452 0(3) nm, β=109. 82 (3)° V=1. 193 3(4) nm3, Z=2, F(000)=624, Dc=1.711 g/cm3, μ(Mo Ka) =12. 08 cm-1, R=0.050 9, wR=0. 139 2.展开更多
The 5-fluorouracil-1-acetic acid (5FuAA) and its Cu! complex (5FuAACu) were synthesized and the date for the crystal complex was obtained. The interaction of 5-fluorouracil-1-acetic acid (5FuAA) and its Cu! complex (5...The 5-fluorouracil-1-acetic acid (5FuAA) and its Cu! complex (5FuAACu) were synthesized and the date for the crystal complex was obtained. The interaction of 5-fluorouracil-1-acetic acid (5FuAA) and its Cu! complex (5FuAACu) with DNA was also investigated by using spectral, viscometric, electrochemical and agarose gel electrophoresis methods. The results of interaction with DNA suggest that both 5FuAA and 5FuAACu can bind to DNA in a static electricity attraction mode. But the attraction of 5FuAACu is greater than that of 5FuAA.展开更多
文摘以甲酸和氢氧化钾为原料,不外加任何溶剂一步合成二甲酸钾。通过单因素实验,考察了原料配比、反应温度和反应时间对产品质量与收率的影响。采用正交实验进一步优化了合成工艺,确定了最佳工艺条件:n(HCOOH)/n(KOH)=2.2、反应温度70℃、反应时间30 m in,在该条件下,二甲酸钾产品收率达98%以上。所得产品经红外光谱分析及熔点测定,其结果与文献报道一致。反应过程绿色化,有很好的原子经济性。
文摘The crystal of [Cu(L-His) (Phen)]·2ClO4·H2O was synthesized and characterized by element analysis, molar conductivity, UV, IR and X-ray single crystal structure. The crystal belongs to monoclinic system, space group P21, with a=1. 222 7(2) nm, b=0. 714 5(14) nm, c=1. 452 0(3) nm, β=109. 82 (3)° V=1. 193 3(4) nm3, Z=2, F(000)=624, Dc=1.711 g/cm3, μ(Mo Ka) =12. 08 cm-1, R=0.050 9, wR=0. 139 2.
文摘The 5-fluorouracil-1-acetic acid (5FuAA) and its Cu! complex (5FuAACu) were synthesized and the date for the crystal complex was obtained. The interaction of 5-fluorouracil-1-acetic acid (5FuAA) and its Cu! complex (5FuAACu) with DNA was also investigated by using spectral, viscometric, electrochemical and agarose gel electrophoresis methods. The results of interaction with DNA suggest that both 5FuAA and 5FuAACu can bind to DNA in a static electricity attraction mode. But the attraction of 5FuAACu is greater than that of 5FuAA.
