A novel approach for the efficient synthesis of 2-phosphinoylindoles has been devised through P-centered anion nucleophilic addition to 2-isocyanobenzaldehydes,followed by cascade cyclization.This method uniquely empl...A novel approach for the efficient synthesis of 2-phosphinoylindoles has been devised through P-centered anion nucleophilic addition to 2-isocyanobenzaldehydes,followed by cascade cyclization.This method uniquely employs base-promoted activation without requiring metals,light,or electrical energy,thereby offering a metal-free strategy for constructing phosphine-functionalized indoles.展开更多
A palladium-catalyzed three-component annulation of anilines,alkyne esters,and alkynes has been developed for the synthesis of polysubstituted pyrroles.The protocol demonstrates broad substrate scope and good function...A palladium-catalyzed three-component annulation of anilines,alkyne esters,and alkynes has been developed for the synthesis of polysubstituted pyrroles.The protocol demonstrates broad substrate scope and good functional group compatibility.The application experiments including gram-scale synthesis and derivatization of the product are performed to illustrate the synthetic potential.This method offers mild conditions and efficient access to polysubstituted pyrroles.展开更多
The method of Adler was improved to prepare a series of 5,10,15,20-tetrakis(4-alkoxyphenyl)porphyrins and their complexes containing Fe3+, Mn3+, Pb2+, Co2+, Cu2+, Zn2+. Among them there were seven new compounds. All t...The method of Adler was improved to prepare a series of 5,10,15,20-tetrakis(4-alkoxyphenyl)porphyrins and their complexes containing Fe3+, Mn3+, Pb2+, Co2+, Cu2+, Zn2+. Among them there were seven new compounds. All these compounds were identified through 1H NMR, MS, IR, UV and Element analysis. The correlation between the structure of compounds and their 1H NMR, MS, IR, UV spectra was discussed and their specific spectra were explained. We found nine metalloporphyrins exhibited liquid crystal behaviour through DSC and polarized-light microscope. They had one to three mesophases and certain phase transition temperature, ?H and temperature range of L.C(?T).展开更多
Surface Enhanced Raman Scattering (SERS) of tetrasodium meso-tetrakis (4-sulfonatophenyl) porphine (H2TSPP) and silver tetraphenylporphyrin (Ag(Ⅱ)TSPP)adsorbed spontarleously on uniform Fe3O4 colloids are recorded. T...Surface Enhanced Raman Scattering (SERS) of tetrasodium meso-tetrakis (4-sulfonatophenyl) porphine (H2TSPP) and silver tetraphenylporphyrin (Ag(Ⅱ)TSPP)adsorbed spontarleously on uniform Fe3O4 colloids are recorded. The enhancement of Raman bands is approximately 30. An analysis of the SERS spectrum shows that on the Fe3O4 surface H2TSPP takes its diacid form H42+TSPP.展开更多
基金Project supported by the National Natural Science Foundation of China(Nos.22301160,21702121,21602123)the Programme of Introducing Talents of Discipline to Universities(111 Project,No.D20015)+3 种基金the Natural Science Foundation of Hubei Province(Nos.2025AFA116,2025AFD270,2023AFB026)the China Postdoctoral Science Foundation(No.2023M742043)the Hubei Three Gorges Laboratory Foundation(Nos.SC240014,SC232008,SC213008)the Foundation of Hubei Key Laboratory of Natural Products Research and Development(Nos.2024NPRD08,2022NPRD04)。
文摘A novel approach for the efficient synthesis of 2-phosphinoylindoles has been devised through P-centered anion nucleophilic addition to 2-isocyanobenzaldehydes,followed by cascade cyclization.This method uniquely employs base-promoted activation without requiring metals,light,or electrical energy,thereby offering a metal-free strategy for constructing phosphine-functionalized indoles.
文摘A palladium-catalyzed three-component annulation of anilines,alkyne esters,and alkynes has been developed for the synthesis of polysubstituted pyrroles.The protocol demonstrates broad substrate scope and good functional group compatibility.The application experiments including gram-scale synthesis and derivatization of the product are performed to illustrate the synthetic potential.This method offers mild conditions and efficient access to polysubstituted pyrroles.
文摘The method of Adler was improved to prepare a series of 5,10,15,20-tetrakis(4-alkoxyphenyl)porphyrins and their complexes containing Fe3+, Mn3+, Pb2+, Co2+, Cu2+, Zn2+. Among them there were seven new compounds. All these compounds were identified through 1H NMR, MS, IR, UV and Element analysis. The correlation between the structure of compounds and their 1H NMR, MS, IR, UV spectra was discussed and their specific spectra were explained. We found nine metalloporphyrins exhibited liquid crystal behaviour through DSC and polarized-light microscope. They had one to three mesophases and certain phase transition temperature, ?H and temperature range of L.C(?T).
文摘Surface Enhanced Raman Scattering (SERS) of tetrasodium meso-tetrakis (4-sulfonatophenyl) porphine (H2TSPP) and silver tetraphenylporphyrin (Ag(Ⅱ)TSPP)adsorbed spontarleously on uniform Fe3O4 colloids are recorded. The enhancement of Raman bands is approximately 30. An analysis of the SERS spectrum shows that on the Fe3O4 surface H2TSPP takes its diacid form H42+TSPP.
