This paper presents a theoretical method for predicting the effective diffusion coefficient of macromolecules in the microporous membrfines in view of the effects of molecular dimension and configuration. On the basi...This paper presents a theoretical method for predicting the effective diffusion coefficient of macromolecules in the microporous membrfines in view of the effects of molecular dimension and configuration. On the basis of the hindered diffusion theory of spherical neutral macromolecules in a micropore of a long cylinder, the effects of molecular dimension and configuration are studied by defining two molecular dimensions:the mean projected radius to predict the concentration partition and the ' hydrodynamically equivalent sphere' radius to evaluate the hydrodynamic reverse drag force. The quantitative comparison shows that the effective diffusion coefficients for different macromolecules predicted by the present method are more consistent with the available published experimental data.展开更多
文摘This paper presents a theoretical method for predicting the effective diffusion coefficient of macromolecules in the microporous membrfines in view of the effects of molecular dimension and configuration. On the basis of the hindered diffusion theory of spherical neutral macromolecules in a micropore of a long cylinder, the effects of molecular dimension and configuration are studied by defining two molecular dimensions:the mean projected radius to predict the concentration partition and the ' hydrodynamically equivalent sphere' radius to evaluate the hydrodynamic reverse drag force. The quantitative comparison shows that the effective diffusion coefficients for different macromolecules predicted by the present method are more consistent with the available published experimental data.
