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敦煌藏文文献中“Gling-gi-khri-rtse”的功能演变与地理位置
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作者 普哇杰 《攀登(藏文版)》 2026年第1期108-116,共9页
敦煌藏文文献中所见“Gling-gi-khri-rtse”一名,长期以来,学界对其地理位置及所属赞普问题存在争议。通过对比文献与分析历史语境可知,该名称最初指代吐蕃时期的一座王室宫殿,功能上与同期宫殿“on-cang-do”相似,经历了从王权空间向... 敦煌藏文文献中所见“Gling-gi-khri-rtse”一名,长期以来,学界对其地理位置及所属赞普问题存在争议。通过对比文献与分析历史语境可知,该名称最初指代吐蕃时期的一座王室宫殿,功能上与同期宫殿“on-cang-do”相似,经历了从王权空间向佛教藏经场所的演变过程。关于其地理位置,既有“四川德格说”,也有“青海贵德说”,结合藏文史料与地理方位考证可提出,“Gling-gi-khri-rtse”实际位于青、川、甘三省交界的在黄河首曲流域,具体指向今甘肃省玛曲县阿万仓地区。这一结论为吐蕃时期河湟流域的权力格局与佛教传播研究提供了新的地理坐标。 展开更多
关键词 黄河首曲 Gling-gi-khri-rtse 地名 玛曲县
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In Memory of Wolter J.Fabrycky:A Pioneer of Systems Engineering and US-Sino Academic Exchange
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作者 Fei-Yue Wang 《IEEE/CAA Journal of Automatica Sinica》 2025年第5期839-840,共2页
The passing of Professor Wolter“Wolt”Fabrycky,an outstanding member and great leader,is a big loss to our international systems engineering professional community.“Wolt was a legend in the systems engineering commu... The passing of Professor Wolter“Wolt”Fabrycky,an outstanding member and great leader,is a big loss to our international systems engineering professional community.“Wolt was a legend in the systems engineering community with his teaching,advising,and dissemination of knowledge through the books he authored.”,as stated by Professor Eileen Aken,a former student of Wolt and the head of the Virginia Tech’s Grado Department of Industrial and Systems Engineeirng where Wolt had served and led for 30 years and retired as John L.Lawrence Professor emeritus. 展开更多
关键词 dissemination knowledge academic exchange international community industrial systems engineeirng systems engineering knowledge dissemination LEADERSHIP
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The Unbroken Thread-Celebrating the 80th Birthday of Prof.Qing-Shi Zhu
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作者 Shui-Ming Hu Lifeng Yan 《Chinese Journal of Chemical Physics》 2026年第1期1-2,共2页
This special issue honors Professor Qing-Shi Zhu on his 80th birthday.The papers collected here,contribut-ed by his former students and colleagues across physi-cal chemistry,reflect the remarkable breadth and last-ing... This special issue honors Professor Qing-Shi Zhu on his 80th birthday.The papers collected here,contribut-ed by his former students and colleagues across physi-cal chemistry,reflect the remarkable breadth and last-ing influence of his scientific and educational legacy.Across five decades,his career has been defined by foun-dational contributions to molecular spectroscopy. 展开更多
关键词 scientific legacy educational influence molecular spectroscopy physical chemistry
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甘肃宁县石家墓地MK5发掘简报 被引量:1
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作者 张俊民 王永安 +2 位作者 李悦 景小庆(执笔/绘图) 孙锋(绘图) 《考古与文物》 北大核心 2025年第6期3-4,I0001,I0002,5-17,共17页
石家墓地位于甘肃省庆阳市宁县早胜镇西头村。2016年,甘肃省文物考古研究所首次对石家墓地进行了发掘,共清理春秋时期墓葬12座、车马坑2座和祭祀坑1座。在车马坑MK5内发现东西向纵列的殉车5辆,其中1辆车无马,4辆车为一驾两马。车马下发... 石家墓地位于甘肃省庆阳市宁县早胜镇西头村。2016年,甘肃省文物考古研究所首次对石家墓地进行了发掘,共清理春秋时期墓葬12座、车马坑2座和祭祀坑1座。在车马坑MK5内发现东西向纵列的殉车5辆,其中1辆车无马,4辆车为一驾两马。车马下发现有殉人、殉狗。此车马坑具有典型春秋中期秦文化的特点。 展开更多
关键词 甘肃宁县 石家墓地 车马坑 春秋中期 秦文化
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4.5—4.0kaB.P.气候变化、人口增长、条件限制与黄河中下游地区龙山酋邦社会产生 被引量:18
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作者 吴文祥 葛全胜 《第四纪研究》 CAS CSCD 北大核心 2014年第1期253-265,共13页
黄河中下游地区龙山时代中晚期(4.5~4.0kaB.P.)酋邦社会的产生是我国史前社会演进过程中一个重要事件,关于其形成机制,学者提出了各种假说或理论,然而到目前为止,还没有一种理论能够给出令人满意的解释。本文首先根据考古和... 黄河中下游地区龙山时代中晚期(4.5~4.0kaB.P.)酋邦社会的产生是我国史前社会演进过程中一个重要事件,关于其形成机制,学者提出了各种假说或理论,然而到目前为止,还没有一种理论能够给出令人满意的解释。本文首先根据考古和历史文献证据,揭示出龙山时代中晚期战争盛行的社会现象,从而支持了国际学术界关于战争是史前社会演化主要驱动力理论;然后利用多种自然气候记录恢复了龙山时代气候变化历史,发现龙山时代中晚期,即大约4.5~4.0kaB.P.发生了显著气候变化,其发生时间与黄河中下游地区龙山酋邦社会产生的时间比较吻合,暗示二者之间存在某种联系。另外结合人口学和社会演进理论,尝试提出另一种可供检验的假说,即认为在主要由于人口增长形成的限制条件下,气候变化作用于一定人口规模之上,引起人口一资源失衡,并进而触发的冲突和战争是黄河中下游地区酋邦社会产生的主要动因。 展开更多
关键词 4 5~4 0kaB P 气候变化 黄河中下游地区 龙山时代 酋邦社会动因
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基于K-means聚类方法的早期聚落规模等级研究 被引量:6
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作者 闫丽洁 张嫣文 +3 位作者 鲁鹏 陈盼盼 张莉 王霞 《地域研究与开发》 CSSCI CSCD 北大核心 2020年第2期176-180,共5页
选择聚落面积、文化层厚度、重要遗物、重要遗迹四大影响聚落规模等级的因子作为参评因子,通过数据预处理、数据归一化操作,利用K-means聚类方法对华夏文明核心区——环嵩山地区在裴李岗、仰韶、龙山、夏商4个时期的聚落规模等级进行划... 选择聚落面积、文化层厚度、重要遗物、重要遗迹四大影响聚落规模等级的因子作为参评因子,通过数据预处理、数据归一化操作,利用K-means聚类方法对华夏文明核心区——环嵩山地区在裴李岗、仰韶、龙山、夏商4个时期的聚落规模等级进行划分。结果表明:(1)不同时期一级聚落的面积越来越大,在每个文化时期聚落中所占的比例却是越来越小。(2)各个文化时期的聚落数量有明显的等级分布特点,呈金字塔型层级结构,等级越高数量越少,等级越低数量越多。(3)裴李岗时期聚落等级规模之间的差异不明显。仰韶时期,聚落规模等级开始出现,龙山时期聚落规模等级进一步分化,夏商时期聚落规模等级最终形成。K-means聚类方法是早期聚落规模等级划分的科学有效的定量方法,可为区域文明化进程及聚落分布形态、聚落功能等问题研究提供重要依据。 展开更多
关键词 早期聚落 规模等级 K-means聚类方法 环嵩山地区
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423例结直肠癌KRAS/NRAS/BRAF/PIK3CA基因突变与临床病理的关系分析 被引量:12
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作者 朱凤伟 吕亚莉 +4 位作者 钟梅 董周寰 王琼 谭心睿 石怀银 《解放军医学院学报》 CAS 2019年第10期976-980,共5页
目的分析结直肠癌(colorectal cancer,CRC)肿瘤组织中KRAS/NRAS/BRAF/PIK3CA基因突变与临床病理的关系。方法选取2014年7月-2019年5月于解放军总医院第一医学中心行手术切除的423例原发性CRC患者肿瘤组织标本进行回顾性分析,采用扩增阻... 目的分析结直肠癌(colorectal cancer,CRC)肿瘤组织中KRAS/NRAS/BRAF/PIK3CA基因突变与临床病理的关系。方法选取2014年7月-2019年5月于解放军总医院第一医学中心行手术切除的423例原发性CRC患者肿瘤组织标本进行回顾性分析,采用扩增阻滞突变系统与Taqman探针相结合的方法检测KRAS/NRAS/BRAF/PIK3CA基因的体细胞突变热点,分析其与临床病理特征的关系。结果423例CRC中,4种基因(KRAS/NRAS/BRAF/PIK3CA)总突变率为58.87%(249/423),其中KRAS突变率为44.68%(189/423),NRAS突变率为4.73%(20/423),BRAF突变率为3.78%(16/423),PIK3CA突变率为5.67%(24/423)。此外还发现KRAS和PIK3CA共同突变率为3.07%(13/423);BRAF和PIK3CA共同突变率为0.95%(4/423)。KRAS基因在脉管内癌栓[OR:0.351,P=0.003]和淋巴结转移[OR:0.583,P=0.006]病例中突变率明显降低;NRAS基因在肿瘤高分化组(OR:5.984,P=0.026)中突变率明显升高。BRAF基因在右半结肠肿瘤中突变频率明显升高[OR:4.286,P=0.005]。KRAS、NRAS、BRAF和PIK3CA基因突变与性别、年龄、肿瘤大小、大体分型、神经侵犯、肝转移和临床分期等因素无关(P均>0.05)。结论本组结直肠癌患者中KRAS、NRAS、BRAF和PIK3CA这4个基因突变与大部分临床病理指标无关,但是KRAS突变较少出现在脉管内癌栓和淋巴结转移患者中,BRAF突变更多地出现在右半结肠。 展开更多
关键词 结直肠癌 KRAS基因 NRAS基因 BRAF基因 PIK3CA基因 基因突变 病理学
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结直肠癌中FAK、FAK pY397、Akt、NF-κB表达及相关性研究 被引量:13
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作者 陈玉英 陈克力 +5 位作者 潘凤 杨黎 李建军 向浏欣 何建明 梁后杰 《临床肿瘤学杂志》 CAS 2009年第3期199-202,共4页
目的:检测黏着斑激酶(FAK)、磷酸化FAK(FAK pY397)、Akt和细胞核因子(NF-κB)在结直肠癌组织中的表达,并探讨其相关性。方法:采用免疫组织化学SP法,检测74例结直肠癌组织与10例正常结肠组织中FAK、FAK pY397、Akt和NF-κB的表达。结果:... 目的:检测黏着斑激酶(FAK)、磷酸化FAK(FAK pY397)、Akt和细胞核因子(NF-κB)在结直肠癌组织中的表达,并探讨其相关性。方法:采用免疫组织化学SP法,检测74例结直肠癌组织与10例正常结肠组织中FAK、FAK pY397、Akt和NF-κB的表达。结果:结直肠癌组织标本中FAK、FAK pY397、Akt和NF-κB的阳性率分别为82.43%、45.95%、52.70%和59.46%,除FAK pY397外,FAK、Akt、NF-κB均与正常结肠壁组织表达的差异显著(P<0.05)。FAK表达与分化程度、淋巴结转移有关(P<0.05),但不受患者性别、年龄、肿瘤的大小及位置、Dukes分期的影响。Akt阳性表达与分化程度显著相关(P<0.05),NF-κB表达与淋巴结转移显著有关(P<0.05),并且Akt、NF-κB表达与FAK表达呈显著正相关(P<0.05)。结论:FAK、Akt、NF-κB在结直肠癌组织中均高表达,且Akt、NF-κB表达与FAK有显著正相关性,提示生存信号传导通路FAK/Akt/NF-κB在结直肠癌的发生、演进中起重要作用。 展开更多
关键词 黏着斑激酶 AKT 核因子一KB 结直肠癌
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Krüppel样转录因子8(KLF8)的结构及功能 被引量:7
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作者 万伟峰 朱继 +2 位作者 方升 籍新潮 吕国伟 《中国生物化学与分子生物学报》 CAS CSCD 北大核心 2011年第4期305-309,共5页
Krüppel样转录因子8(Krüppel-like factor 8,KLF8)是KLFs家族中的一员.KLF8在羧基端含有3个保守的C2H2锌指结构域,用于与DNA结合.KLF8的转录受粘着斑激酶(focal adhesionkinase,FAK)、KLF1(erythroid krüppel-like facto... Krüppel样转录因子8(Krüppel-like factor 8,KLF8)是KLFs家族中的一员.KLF8在羧基端含有3个保守的C2H2锌指结构域,用于与DNA结合.KLF8的转录受粘着斑激酶(focal adhesionkinase,FAK)、KLF1(erythroid krüppel-like factor1)、KLF3(basic Krüppel-like factor)的调控.类泛素化是KLF8翻译后主要的修饰方式.KLF8在氨基端含有特定的PVALS/T基序,与辅助抑制因子C末端结合蛋白(C-terminal binding protein,CtBP)相互作用,抑制调节区含CACCC元件的基因表达.此外,还可以通过招募辅助激活因子p300和p300/CBP相关因子(P/CAF)辅助激活靶基因的表达.同时,KLF8在细胞周期循环、细胞侵袭和上皮-间质转化(epithelial to mesenchymal transition,EMT)、细胞致癌性转化及肿瘤发生发展中发挥作用. 展开更多
关键词 Krüppel样转录因子8(KLF8) 上皮-间质转化(EMT) 粘着斑激酶(FAK) 细胞周期素D1
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A Tribute to Prof.Fanao Kong
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《Chinese Journal of Chemical Physics》 2025年第5期521-522,共2页
Professor Fanao Kong(孔繁敖)was born on June 9th,1936,in Wuhan,Hubei Province.He later relocated with his family to Shanghai,where he completed his senior high school education at Shanghai High School.He then was educ... Professor Fanao Kong(孔繁敖)was born on June 9th,1936,in Wuhan,Hubei Province.He later relocated with his family to Shanghai,where he completed his senior high school education at Shanghai High School.He then was educated in the Department of Chemistry at Peking University.After graduation in 1958,he joined the faculty of the University of Science and Technology of China(USTC)which was newly founded in that year.In addition to his dedicated teaching and scientific research at the USTC,he participated in the establishment of the Laser Chemistry Laboratory in the Department of Chemical Physics. 展开更多
关键词 PROFESSOR University Science Technology China Chemistry scientific research Peking University Chemical Physics Fanao Kong Laser Chemistry Laboratory
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A New Chapter of Mutual Learning among Civilisations along the Silk Road Was Written in Dunhuang
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《International Understanding》 2025年第2期8-11,共4页
In the thousand-year-old mural of Mogao Grottoes in Dunhuang,a special symbol tells the story of exchanges among civilisations.Three Rabbits Sharing Three Ears depicts three rabbits chasing each other,with each two sh... In the thousand-year-old mural of Mogao Grottoes in Dunhuang,a special symbol tells the story of exchanges among civilisations.Three Rabbits Sharing Three Ears depicts three rabbits chasing each other,with each two sharing one ear.It is said that its earliest version appeared in Dunhuang in the 6th century,and it had travelled across the desert along the ancient Silk Road,over mountains and rivers,leaping onto British ceramic tiles,integrating into Egyptian pottery and jumping cross the clock faces of German churches. 展开更多
关键词 dunhuang mogao grottoes mutual learning MURAL civilisations jumping cross clock faces rabbits sharing three ears silk road
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Global Dialogue on Civilisational Inheritance and the Digital Silk Road
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《International Understanding》 2025年第2期16-17,共2页
On the afternoon of May 30,the parallel forum"Global Dialogue on Civilisational Inheritance and the Digital Silk Road,"as part of the 4th Dialogue on Exchanges and Mutual Learning among Civilisations,was hel... On the afternoon of May 30,the parallel forum"Global Dialogue on Civilisational Inheritance and the Digital Silk Road,"as part of the 4th Dialogue on Exchanges and Mutual Learning among Civilisations,was held in Dunhuang.The forum focused on key areas of Silk Road civilisation studies in the new era under the theme"Carrying Forward the Silk Road Spirit and Pooling Strength for the Implementation of the Global Civilisation Initiative."Discussions centred on topics such as humanistic research on the Digital Silk Road,translation studies of cultural heritage,and archaeological studies of Silk Road sites,providing a platform for experts and scholars to exchange ideas and share achievements,and working to build a strong synergy for exchanges and mutual learning among civilisations. 展开更多
关键词 Digital Silk Road silk road global dialogue civilisational inheritance exchanges mutual learning humanistic research parallel forumglobal Dunhuang
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Two species of microcracks 被引量:8
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作者 Stuart Crampin 高原 《Applied Geophysics》 SCIE CSCD 2014年第1期1-8,115,共9页
We identify two interrelated but independent species of microcracks with different origins and different distributions. One species is the classic high-stress microcracks identified in laboratory stress-cells associat... We identify two interrelated but independent species of microcracks with different origins and different distributions. One species is the classic high-stress microcracks identified in laboratory stress-cells associated with acoustic emissions as microcracks open with increasing stress. The other species is the low-stress distributions of closely-spaced stress-aligned fluid-saturated microcracks that observations of shear-wave splitting(SWS) demonstrate pervade almost all in situ rocks in the upper crust, the lower crust, and the uppermost 400 km of the mantle. On some occasions these two sets of microcracks may be interrelated and similar(hence ‘species') but they typically have fundamentally-different properties, different distributions, and different implications. The importance for hydrocarbon exploration and recovery is that SWS in hydrocarbon reservoirs monitors crack alignments and preferred directions of fluid-flow. The importance for earthquake seismology is that SWS above small earthquakes monitors the effects of increasing stress on the pervasive low-stress microcrack distributions so that stress-accumulation before, possibly distant, earthquakes can be recognised and impending earthquakes stress-forecast. 展开更多
关键词 crack-induced anisotropy fluid-saturate microcracks shearwave splitting stressforecasting earthquakes two species of microcracks
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Lost Silk Road cities in Central Asian mountains
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作者 郭歌 《疯狂英语(新悦读)》 2025年第3期13-15,75,共4页
1 Researchers have discovered the remains of ancient cities located above the ancient Silk Road in the rocky mountains of southeastern Uzbekistan.The groundbreaking discovery,made possible by new drone‑based lidar(激... 1 Researchers have discovered the remains of ancient cities located above the ancient Silk Road in the rocky mountains of southeastern Uzbekistan.The groundbreaking discovery,made possible by new drone‑based lidar(激光雷达)technology,challenges long‑held assumptions that urban life was rarely seen in the remote mountains of Central Asia. 展开更多
关键词 urban life Silk Road silk road ancient cities MOUNTAINS central Asia drone based lidar
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海曼·巴斯:代数K-理论的奠基人
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作者 王勇兵 王淑红 《自然辩证法通讯》 北大核心 2025年第10期111-121,共11页
海曼·巴斯是20世纪美国著名数学家和数学教育家,2006年美国国家科学奖获得者。巴斯在代数K-理论、数论、群论、代数几何学领域作出了重要贡献,建立了代数K-理论这一数学分支。巴斯担任了美国数学会主席和国际数学教育委员会主席,... 海曼·巴斯是20世纪美国著名数学家和数学教育家,2006年美国国家科学奖获得者。巴斯在代数K-理论、数论、群论、代数几何学领域作出了重要贡献,建立了代数K-理论这一数学分支。巴斯担任了美国数学会主席和国际数学教育委员会主席,对数学与数学教育的发展产生了深远影响。此外,巴斯及弟子与中国学者也有密切的学术联系,间接推动了中国现代数学的发展。 展开更多
关键词 海曼·巴斯 代数K-理论 数学教育 美国数学会
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Medical and Folklore Images during Pandemics:A Study of Edo Period Epidemic Visual Culture
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作者 ZENG Yi XIAO Yongzhi 《Chinese Medicine and Culture》 2025年第2期124-138,共15页
Edo-period historical records and documents preserved a substantial number of images,many of which are related to epidemic outbreaks.Through systematic collation and categorical analysis,this study uses the chronologi... Edo-period historical records and documents preserved a substantial number of images,many of which are related to epidemic outbreaks.Through systematic collation and categorical analysis,this study uses the chronological and thematic characteristics of these images as a framework to examine the response mechanisms of the Japanese government and public during infectious disease pandemics in the Edo period,as well as the multidimensional impacts of epidemics on social economy,culture,and customs.Illustrations of smallpox in medical texts reveal the developmental trajectory of Japan’s traditional medical knowledge system,while drawings in essays and diaries reflect public fear and non-medical cognitive patterns during cholera outbreaks.Epidemic-themed paintings not only document cholera treatment protocols by the government and medical professionals,as well as grassroots prevention and treatment practices for measles,but also vividly depict social dynamics during crises.Images related to epidemics in advertising reflect the prosperity of the pharmaceutical industry in the Edo period,while depictions in folding screens,ukiyozoushi and the occupational illustrations demonstrate societal customs for epidemic response.Collectively,the Edo-period epidemic crises profoundly shaped Japan’s medical system,economic structure,cultural forms,folk traditions,and public psychology,prompting the government,medical professionals,and civilians to develop distinct era-specific social coping mechanisms. 展开更多
关键词 Edo period EPIDEMIC Folklore images Kampo medicine
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WALKING THROUGH THE LAND OF SNOW
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作者 Yu Minhong(Text/Photos) CTIS(Translated) 《China's Tibet》 2025年第1期60-65,共6页
several months had passed since my trip to Xizang.The 21-day trip to Xizang may not seem long,but I had been looking forward to it for many years.I often told myself that my life should be different after I turned 60-... several months had passed since my trip to Xizang.The 21-day trip to Xizang may not seem long,but I had been looking forward to it for many years.I often told myself that my life should be different after I turned 60-freer and less constrained.So,I let go of everything,packed up,and hit the road to Xizang for 21 days. 展开更多
关键词 packed LOOKING CONSTRAINED
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