Objective： The present study, for the first time, was designed to examine the antifibrosis effects of Shenge Yangfei Capsules（SGYF） on bleomycin-induced pulmonary injury and fibrosis in rats.Methods： Animals were ...Objective： The present study, for the first time, was designed to examine the antifibrosis effects of Shenge Yangfei Capsules（SGYF） on bleomycin-induced pulmonary injury and fibrosis in rats.Methods： Animals were divided into six groups randomly： saline control group, model group（bleomycin5 mg/kg）, and positive control group（Dexamethasone 5 mg/kg）, and SGYF（70, 420, and 850 mg/kg/d, ig）group. Effects of SGYF on body weight and lung index were evaluated. For histological evaluation of lungs injury and fibrosis, lung specimens were stained with hematoxylin and eosin（HE） and Masson trichrome.Body weight and lung index from various groups were measured, and the concentrations of monoamine（MAO） and transforming growth factor-β1（TGF-β1） were also detected in lung homogenates.Results： SGYF attenuated the bleomycin-induced weight loss and the lung index. Histologica levidence showed the ability of SGYF to decrease bleomycin-induced lung fibrosis and consolidation. SGYF reduced MAO and TGF-β1 activity in lung tissues.Conclusions： These findings suggest that SGYF may be a promising candidate to prevent bleomycininduced lung damage or other interstitial lesions.展开更多
Facial attractiveness can be automatically perceived in implicit tasks when the faces are visible.Nonetheless,to date,it is poorly understood to what extent facial attractiveness can be processed when faces are invisi...Facial attractiveness can be automatically perceived in implicit tasks when the faces are visible.Nonetheless,to date,it is poorly understood to what extent facial attractiveness can be processed when faces are invisible.It is also worth exploring the differences between visible and invisible processing of facial attractiveness.To address these issues,the event-related potentials(ERPs)were recorded when participants were presented with attractive and unattractive faces under invisible condition(continuous flash suppression paradigm;CFS)and visible condition(gender judgment task).The results indicated that attractive faces elicited a larger P1 amplitude(110–150ms)compared to unattractive faces,regardless of whether the faces were visible.Attractive faces also elicited a larger N170 amplitude(150–190ms)compared to unattractive faces under the visible condition.Furthermore,visible faces elicited larger P1 and N250/early posterior negativity(EPN)amplitudes as compared to invisible faces.But only under the attractive condition,the visible faces elicited a larger N170 than the invisible faces.The present study suggested that facial attractiveness can be automatically perceived in the early stage regardless of visibility,although attractiveness processing was somewhat reduced in the absence of visual awareness.展开更多
This study examined how culture shapes third-party punishment and compensation in the harm domain using realistic judicial scenarios.Chinese participants showed greater engagement in both forms than American participa...This study examined how culture shapes third-party punishment and compensation in the harm domain using realistic judicial scenarios.Chinese participants showed greater engagement in both forms than American participants,with individualism-collectivism values mediating these societal differences.展开更多
基金financially supported by Guanghua Fund(No.413FZ08)
文摘Objective： The present study, for the first time, was designed to examine the antifibrosis effects of Shenge Yangfei Capsules（SGYF） on bleomycin-induced pulmonary injury and fibrosis in rats.Methods： Animals were divided into six groups randomly： saline control group, model group（bleomycin5 mg/kg）, and positive control group（Dexamethasone 5 mg/kg）, and SGYF（70, 420, and 850 mg/kg/d, ig）group. Effects of SGYF on body weight and lung index were evaluated. For histological evaluation of lungs injury and fibrosis, lung specimens were stained with hematoxylin and eosin（HE） and Masson trichrome.Body weight and lung index from various groups were measured, and the concentrations of monoamine（MAO） and transforming growth factor-β1（TGF-β1） were also detected in lung homogenates.Results： SGYF attenuated the bleomycin-induced weight loss and the lung index. Histologica levidence showed the ability of SGYF to decrease bleomycin-induced lung fibrosis and consolidation. SGYF reduced MAO and TGF-β1 activity in lung tissues.Conclusions： These findings suggest that SGYF may be a promising candidate to prevent bleomycininduced lung damage or other interstitial lesions.
基金supported by Humanities and Social Sciences Research Project of the Ministry of Education,23YJAZH119the National Natural Science Foundation of China(31400869)+2 种基金the Education Science Planning Project of Jiangsu Province(B-b/2024/01/38)the Social Science Application Research Boutique Engineering Project of Jiangsu Province(23SYB-112)the Start-up Research Fund of Southeast University(RF1028623132).
文摘Facial attractiveness can be automatically perceived in implicit tasks when the faces are visible.Nonetheless,to date,it is poorly understood to what extent facial attractiveness can be processed when faces are invisible.It is also worth exploring the differences between visible and invisible processing of facial attractiveness.To address these issues,the event-related potentials(ERPs)were recorded when participants were presented with attractive and unattractive faces under invisible condition(continuous flash suppression paradigm;CFS)and visible condition(gender judgment task).The results indicated that attractive faces elicited a larger P1 amplitude(110–150ms)compared to unattractive faces,regardless of whether the faces were visible.Attractive faces also elicited a larger N170 amplitude(150–190ms)compared to unattractive faces under the visible condition.Furthermore,visible faces elicited larger P1 and N250/early posterior negativity(EPN)amplitudes as compared to invisible faces.But only under the attractive condition,the visible faces elicited a larger N170 than the invisible faces.The present study suggested that facial attractiveness can be automatically perceived in the early stage regardless of visibility,although attractiveness processing was somewhat reduced in the absence of visual awareness.
基金supported by the National Social Science Fund of China(24BSH102).
文摘This study examined how culture shapes third-party punishment and compensation in the harm domain using realistic judicial scenarios.Chinese participants showed greater engagement in both forms than American participants,with individualism-collectivism values mediating these societal differences.
