Infrared(IR) optics have garnered significant attention due to growing demands in advanced optical imaging,communication, detection, and sensing. Among various IR devices, microlenses and microlens arrays offer distin...Infrared(IR) optics have garnered significant attention due to growing demands in advanced optical imaging,communication, detection, and sensing. Among various IR devices, microlenses and microlens arrays offer distinct advantages in integration capability, imaging precision, multifunctionality, and cost-effective manufacturing. We present a novel design of high-resolution achromatic microlens in the mid-IR region. Different from traditional high-refractive-index convex microlenses embedded within a low-index background medium, the current design is a low-index air concave microlens embedded within a high-index silicon medium. The designed air microlens exhibits capabilities in high-resolution imaging(~λ/6) and achromatic performance across the 3–5 μm mid-IR spectrum. The air microlens could be assembled in large-area microlens arrays or as part of multi-lens system.When combined with the HgCdTe detector system placed on the focal plane, the air microlens can find promising applications in high-resolution optical imaging and high-sensitivity photoelectric detection.展开更多
When a pump laser beam strikes the surface of a nonlinear crystal with modulated second-order nonlinearity,various nonlinear diffraction phenomena occur,with nonlinear Raman–Nath diffraction(NRND)being a prominent ex...When a pump laser beam strikes the surface of a nonlinear crystal with modulated second-order nonlinearity,various nonlinear diffraction phenomena occur,with nonlinear Raman–Nath diffraction(NRND)being a prominent example.In this study,we use an 800-nm Ti:sapphire femtosecond laser beam to pump the surface of a periodically poled lithium niobate(PPLN)crystal thin-plate nonlinear grating.By rotating the crystal,we change the incidence angle and observe and measure the exit angle,polarization,and power of NRND spots on the other side of the crystal.The experiment shows that NRND characteristics are highly sensitive to the incidence angle of the pump laser beam,which are consistent with the theoretical prediction.We expect that this research will advance the understanding of nonlinear diffraction and provide valuable insights for nonlinear optical interaction in complicated geometric and physical configurations.展开更多
When a laser beam is incident on a nonlinear grating with a laterally modulated second-order nonlinear coefficient,nonlinear diffraction of the noncollinear second-harmonic generation(SHG)signal occurs,with Raman–Nat...When a laser beam is incident on a nonlinear grating with a laterally modulated second-order nonlinear coefficient,nonlinear diffraction of the noncollinear second-harmonic generation(SHG)signal occurs,with Raman–Nath nonlinear diffraction(NRND)being a prominent example.As these SHG NRND processes involve coupling between the fundamental-wave pump laser vectorial field and the SHG laser vectorial field through the second-order nonlinearity secondrank tensor of the nonlinear crystal,the nonlinear interaction between light and the nonlinear grating can be manipulated by adjusting the polarization state of the pump laser.In this paper,we derive the relationship between the polarization state of the incident light and the generated nonlinear diffraction signal based on the nonlinear coupled wave equation and experimentally validate the predicted diffraction characteristics.The results show that the optical properties of each order of NRND are highly sensitive to the polarization angle of the incident pump laser beam.展开更多
Rayleigh-Taylor instability(RTI)of finite-thickness shell significantly impacts shell deformation and material mixing processes,with crucial implications for inertial confinement fusion(ICF).This study focuses on the ...Rayleigh-Taylor instability(RTI)of finite-thickness shell significantly impacts shell deformation and material mixing processes,with crucial implications for inertial confinement fusion(ICF).This study focuses on the RTI growth at the dual interfaces of a thin shell.A second-order weakly nonlinear(WN)analytical theory is developed to investigate the nonlinear deformation of the shell induced by different perturbation wavelengths initially imposed at the upper and lower interfaces.The validity of the theoretical results within the WN regime has been confirmed via two-dimensional Eulerian numerical simulations.Due to the interface coupling effect,the initially imposed single-mode perturbations at the upper and lower interfaces progressively evolve,exhibiting characteristics typical of multi-mode perturbations.When the initial perturbation wavelengths differ significantly,the primary structure of RTI retains its integrity,a behavior attributed to the dominance of long-wavelength perturbations.For comparable initial wavelengths,mode-coupling significantly distorts the bubble-spike structure in RTI,with the thin shell becoming prone to rupture due to enhanced nonlinear interactions.展开更多
Recent clinical and experimental studies have confirmed the effects of Xinfuli Granule (XG), a compound Chinese medicine in the prevention and treatment of heart failure (HF). This study aimed to investigate the effec...Recent clinical and experimental studies have confirmed the effects of Xinfuli Granule (XG), a compound Chinese medicine in the prevention and treatment of heart failure (HF). This study aimed to investigate the effects and the mechanisms of XG on ventricular reconstruction in rats with acute myocardial infarction (AMI).MethodsSprague-Dawley rats were subjected to left anterior descending branch ligation. The rats that survived 24 h were randomly assigned to five groups: medium-dose of XG group (MI+XGM), high-dose of XG group (MI+XGH), carvedilol group (MI+C), medium-dose of XG + carvedilol group (MI+C+XGM). Fourteen rats underwent identical surgical procedures without artery ligation, serving as sham controls. At 28 days, left ventricular weight to body weight (LVW/BW) and heart weight to body weight (HW/BW) were calculated; left ventricular ejection fraction (LVEF), left ventricular shortening fraction (LVFS), left ventricular internal diameter at systole (LVIDS) were measured by ultrasound; HE staining, Masson staining, and Sirius red staining were used to assess the myocardial pathological and physiological changes as well as myocardial fibrosis area and non-infarct zone I/III collagen ratio. Expression of Smad3 were detected and analyzed by Western blot, immunohistochemistry and immunofluorescence. P-Smad3, Smad2 and Smad7 in the TGF-β/Smads signaling pathway were also analyzed by Western blot.ResultsThe LVIDS (P < 0.01), HW/BW (P < 0.05), type I/III collagen ratio (P < 0.01) and myocardial collagen (P < 0.01) decreased significantly while the LVW/BW, LVFS (P < 0.05) increased significantly in MI+XGM group as compared with those in other groups. The expression of key signal molecules of the TGF-β/Smads signaling pathway, including Smad3, P-Smad3 and Smad2 protein were decreased, while the expression of Smad7 increased in both XG and carvedilol treatment groups as compared to those of the MI group (all P < 0.01). Immunohistochemistry and immunofluorescence further confirmed the down-regulated Smad3 expression.ConclusionXG can improve ventricular reconstruction and inhibit myocardial fibrosis in rats with AMI by regulating TGF-β/Smads signaling pathway.展开更多
The current COVID-19 pandemic urges the extremely sensitive and prompt detection of SARS-CoV-2 virus.Here,we present a Human Angiotensin-converting-enzyme 2(ACE2)-functionalized gold“virus traps”nanostructure as an ...The current COVID-19 pandemic urges the extremely sensitive and prompt detection of SARS-CoV-2 virus.Here,we present a Human Angiotensin-converting-enzyme 2(ACE2)-functionalized gold“virus traps”nanostructure as an extremely sensitive SERS biosensor,to selectively capture and rapidly detect S-protein expressed coronavirus,such as the current SARS-CoV-2 in the contaminated water,down to the single-virus level.Such a SERS sensor features extraordinary 106-fold virus enrichment originating from high-affinity of ACE2 with S protein as well as“virus-traps”composed of oblique gold nanoneedles,and 109-fold enhancement of Raman signals originating from multi-component SERS effects.Furthermore,the identification standard of virus signals is established by machine-learning and identification techniques,resulting in an especially low detection limit of 80 copies mL^(−1) for the simulated contaminated water by SARS-CoV-2 virus with complex circumstance as short as 5 min,which is of great significance for achieving real-time monitoring and early warning of coronavirus.Moreover,here-developed method can be used to establish the identification standard for future unknown coronavirus,and immediately enable extremely sensitive and rapid detection of novel virus.展开更多
Topological photonic states(TPSs)as a new type of waveguide state with one-way transport property can resist backscattering and are impervious to defects,disorders and metallic obstacles.Gyromagnetic photonic crystal(...Topological photonic states(TPSs)as a new type of waveguide state with one-way transport property can resist backscattering and are impervious to defects,disorders and metallic obstacles.Gyromagnetic photonic crystal(GPC)is the first artificial microstructure to implement TPSs,and it is also one of the most important platforms for generating truly one-way TPSs and exploring their novel physical properties,transport phenomena,and advanced applications.Herein,we present a brief review of the fundamental physics,novel properties,and practical applications of TPSs based on GPCs.We first examine chiral one-way edge states existing in uniformly magnetized GPCs of ordered and disordered lattices,antichiral one-way edge states in cross magnetized GPCs,and robust one-way bulk states in heterogeneously magnetized GPCs.Then,we discuss the strongly coupling effect between two co-propagating(or counter-propagating)TPSs and the resulting physical phenomena and device applications.Finally,we analyze the key issues and prospect the future development trends for TPSs in GPCs.The purpose of this brief review is to provide an overview of the main features of TPSs in GPC systems and offer a useful guidance and motivation for interested scientists and engineers working in related scientific and technological areas.展开更多
By the end of 2020,83 silver deposits(or ore occurrences),including four super-large-scale deposits,nine large-scale deposits,33 medium-scale deposits and 37 small-scale deposits or ore occurrences,have been proved.Th...By the end of 2020,83 silver deposits(or ore occurrences),including four super-large-scale deposits,nine large-scale deposits,33 medium-scale deposits and 37 small-scale deposits or ore occurrences,have been proved.The amount of silver metal exceeds 86000 t with average grade of 100 g/t,which makes Daxing’anling region one of the the most important silver ore belt in China.However,the metallogenic characteristics and metallogenesis need to be clarified.The silver deposits in the study area are classified into three main types,which are magmatic hydrothermal vein type,continental volcano-subvolcanic type and skarn type,respectively.The supergiant deposits include the Shuangjianzishan deposit(silver metal amount of 15214 t with average grade of 138 g/t),the Baiyinchagandongshan deposit(silver metal amount of 9446 t with average grade of 187 g/t),the Huaobaote deposit(silver metal amount of 6852 t with average grade of 170 g/t),and the Fuxingtun deposit(silver metal amount of 5240 t with average grade of 196 g/t).The silver deposits are mainly distributed in the central and south of the Daxing’anling area,and mainly formed in the Yanshanian period.The silver polymetallic deposits in the Daxinganling area are significantly controlled by regional faults and the junction zone of volcanic rock basins and their margins.The north-east trending deep faults are the most important ore-controlling structures in this area.The distribution of silver polymetallic deposits along the main faults is obvious,and the intersection area of multiple groups of faults often form important mine catchments.The Permian is the most important ore-bearing formation in this area,but some important silver polymetallic deposits occur in Mesozoic volcanic basins or pre-Mesozoic strata.The magmatic rocks related to mineralization are mainly intermediate acidic or acidic intrusions,intermediate acidic lavas,pyroclastic rocks,and small intrusions of ultra-shallow or shallow facies of the Yanshanian Period.The mineralization element combination is mainly determined by the elemental geochemical background of surrounding rocks or source layers.In addition,the type of deposit,the distance from the mineralization center,and the degree of differentiation of ore-forming rock mass are also important influence factors.The article analyzes the prospecting prospects of each silver deposit type in the study area,discusses the relationship between mineralization center and deep prospecting,and proposes that porphyry silver deposits should be paid attention to.In the prospecting and exploration of silver deposits,comprehensive evaluation and multi-target prospecting need to be strengthened because silver can coexist or be associated with a variety of metals.展开更多
Taking the long-wavelength Rayleigh-Taylor instability(RTI) on the thin shell of inertial confinement fusion as the research object,a linear analytical model is presented to study the phase effects that are caused by ...Taking the long-wavelength Rayleigh-Taylor instability(RTI) on the thin shell of inertial confinement fusion as the research object,a linear analytical model is presented to study the phase effects that are caused by the phase difference of single-mode perturbations on the two interfaces.Its accuracy is tested by numerical simulations.By analyzing the characteristic of this model,it is found that the phase difference does not change the basic RTI structure(only one spike and one bubble in a period).However,the symmetry of the spike and bubble is destroyed,which has non-expected influences on the convergent motion of ICF targets.Meanwhile,the phenomenon that the distance between spikes and bubbles along the vertical direction of acceleration differs by π is demonstrated.It is also shown that when the phase difference is large,the temporal evolution of the RTI is more serious and the thin target is easier to tend to break.展开更多
Antichiral gyromagnetic photonic crystal(GPC)in a honeycomb lattice with the two interpenetrating triangular sublattices A and B magnetically biased in opposite directions can realize antichiral one-way edge states pr...Antichiral gyromagnetic photonic crystal(GPC)in a honeycomb lattice with the two interpenetrating triangular sublattices A and B magnetically biased in opposite directions can realize antichiral one-way edge states propagating along the same direction at its two parallel edges.Here,we report the construction and observation of topological beam splitting with the easily adjustable right-to-left ratio in an antichiral GPC.The splitter is compact and configurable,has high trans-mission efficiency,and allows for multi-channel utilization,crosstalk-proof,and robust against defects and obstacles.This magnificent performance is attributed to the peculiar property that antichiral one-way edge states exist only at zigzag edge but not at armchair edge of antichiral GPC.When we combine two rectangular antichiral GPCs holding left-and right-propagating antichiral one-way edge states respectively,bidirectionally radiating one-way edge states at two paral-lel zigzag edges can be achieved.Our observations can enrich the understanding of fundamental physics and expand to-pological photonic applications.展开更多
The strongly coupled system composed of atoms,molecules,molecule aggregates,and semiconductor quantum dots embedded within an optical microcavity/nanocavity with high quality factor and/or low modal volume has become ...The strongly coupled system composed of atoms,molecules,molecule aggregates,and semiconductor quantum dots embedded within an optical microcavity/nanocavity with high quality factor and/or low modal volume has become an excellent platform to study cavity quantum electrodynamics(CQED),where a prominent quantum effect called Rabi splitting can occur due to strong interaction of cavity-mode single-photon with the two-level atomic states.In this paper,we build a new quantum model that can describe the optical response of the strongly-coupled system under the action of an external probing light and the spectral lineshape.We take the Hamiltonian for the strongly-coupled photon-atom system as the unperturbed Hamiltonian H_(0)and the interaction Hamiltonian of the probe light upon the coupled-system quantum states as the perturbed Hamiltonian V.The theory yields a double Lorentzian lineshape for the permittivity function,which agrees well with experimental observation of Rabi splitting in terms of spectral splitting.This quantum theory will pave the way to construct a complete understanding for the microscopic strongly-coupled system that will become an important element for quantum information processing,nano-optical integrated circuits,and polariton chemistry.展开更多
Birefringence production of light by natural birefringent crystal has long been studied and well understood.Here,we develop a simple and comprehensive rigorous electromagnetic theory that allows one to build up the co...Birefringence production of light by natural birefringent crystal has long been studied and well understood.Here,we develop a simple and comprehensive rigorous electromagnetic theory that allows one to build up the complete picture about the optics of crystals in a friendly way.This theory not only yields the well-known refraction angle and index of ellipse for birefringence crystal,but also discloses many relevant physical and optical quantities that are rarely studied and less understood.We obtain the reflection and transmission coefficient for amplitude and intensity of light at the crystal surface under a given incident angle and show the electromagnetic field distribution within the crystal.We derive the wavefront and energy flux refraction angle of light and the corresponding phase and ray refractive index.We find big difference between them,where the phase refractive index satisfies the classical index of ellipse and Snell’s law,while the ray refractive index does not.Moreover,we disclose the explicit expressions for the zero-reflection Brewster angle and the critical angle for total internal reflection.For better concept demonstration,we take a weak birefringent crystal of lithium niobate and a strong birefringent crystal tellurium as examples and perform simple theoretical calculations.In addition,we perform experimental measurement upon z-cut lithium niobate plate and find excellent agreement between theory and experiment in regard to the Brewster angle.Our theoretical and experimental results can help to construct a clear and complete picture about light transport characteristics in birefringent crystals,and may greatly facilitate people to find rigorous solution to many light-matter interaction processes happening within birefringent crystals,e.g.,nonlinear optical interactions,with electromagnetic theory.展开更多
The Rayleigh-Taylor instability at the weakly nonlinear(WN)stage in spherical geometry is studied by numerical simulation.The mode coupling processes are revealed.The results are consistent with the WN model based on ...The Rayleigh-Taylor instability at the weakly nonlinear(WN)stage in spherical geometry is studied by numerical simulation.The mode coupling processes are revealed.The results are consistent with the WN model based on parameter expansion,while higher order effects are found to be non-negligible.For Legendre mode perturbation Pn(cos B),the nonlinear saturation amplitude(NSA)of the fundamental mode decreases with the mode number n.When n is large,the spherical NSA is lower than the corresponding planar one.However,for large n,the planar NSA can be recovered by applying Fourier transformation to the bubble/spike near the equator and calculating the NSA of the converted trigonometric harmonic.展开更多
Interface width effect on the spherical Rayleigh–Taylor instability in the weakly nonlinear regime is studied by numerical simulations.For Legendre perturbation mode Pn with wave number Kn and interface half-width L,...Interface width effect on the spherical Rayleigh–Taylor instability in the weakly nonlinear regime is studied by numerical simulations.For Legendre perturbation mode Pn with wave number Kn and interface half-width L,the commonly adopted empirical linear growth rate formulaγnem(L)=γn/√1+KnL is found to be sufficient in spherical geometry.At the weakly nonlinear stage,the interface width affects the mode coupling processes.The development of the mode P2n is substantially influenced by the interface width.Moreover,the nonlinear saturation amplitude increases with the interface width.展开更多
A supercontinuum white laser with ultrabroad bandwidth,intense pulse energy,and high spectral flatness can be accomplished via synergic action of third-order nonlinearity(3rd-NL)and second-order nonlinearity.In this w...A supercontinuum white laser with ultrabroad bandwidth,intense pulse energy,and high spectral flatness can be accomplished via synergic action of third-order nonlinearity(3rd-NL)and second-order nonlinearity.In this work,we employ an intense Ti:sapphire femtosecond laser with a pulse duration of 50 fs and pulse energy up to 4 mJ to ignite the supercontinuum white laser.Remarkably,we use water instead of the usual solid materials as the 3rd-NL medium exhibiting both strong self-phase modulation and stimulated Raman scattering effect to create a supercontinuum laser with significantly broadened bandwidth and avoid laser damage and destruction.Then the supercontinuum laser is injected into a water-embedded chirped periodically poled lithium niobate crystal that enables broadband and high-efficiency second-harmonic generation.The output white laser has a 10 dB bandwidth encompassing 413 to 907 nm,more than one octave,and a pulse energy of 0.6 mJ.This methodology would open up an efficient route to creating a long-lived,high-stability,and inexpensive white laser with intense pulse energy,high spectral flatness,and ultrabroad bandwidth for application to various areas of basic science and high technology.展开更多
Raman spectroscopy offers a great power to detect,analyze and identify molecules,and monitor their temporal dynamics and evolution when combined with single-molecule surface-enhanced Raman scattering(SM-SERS)substrate...Raman spectroscopy offers a great power to detect,analyze and identify molecules,and monitor their temporal dynamics and evolution when combined with single-molecule surface-enhanced Raman scattering(SM-SERS)substrates.Here we present a SM-SERS scheme that involves simultaneously giant chemical enhancement from WS22D materials,giant electromagnetic enhancement from plasmonic nanogap hot spot,and inhibition of molecular fluorescence influence under near-infrared laser illumination.Remarkably we find Coulomb attraction between analyte and gold nanoparticle can trigger spontaneous formation of molecule-hotspot pairing with high precision,stability and robustness.The scheme has enabled realization of universal,robust,fast,and large-scale uniform SM-SERS detection for three Raman molecules of rhodamine B,rhodamine 6G,and crystal violet with a very low detection limit of 10−16 M and at a very fast spectrum acquisition time of 50 ms.展开更多
Spin-momentum locking is widely regarded as an inherent property of evanescent waves,where the transverse spin angular momentum is intrinsically tied to the wave's polarization.This principle is well established i...Spin-momentum locking is widely regarded as an inherent property of evanescent waves,where the transverse spin angular momentum is intrinsically tied to the wave's polarization.This principle is well established in systems such as surface plasmon polaritons,surface elastic waves,and other evanescent modes.Here,we theoretically unveil an anomalous breakdown of spin-momentum locking in evanescent electromagnetic waves at a metalgyromagnetic interface.We show that the hybrid polarization of the field induces two successive reversals of transverse spin near the interface—directly violating the conventional locking between spin and momentum.As a result,identical chiral sources placed at different heights above the interface excite evanescent waves propagating in opposite directions,defying standard expectations.This discovery challenges the presumed universality of spin-momentum locking and opens new degrees of freedom for controlling wave propagation in photonic and plasmonic systems.展开更多
The main active components extracted from Panax notoginseng are total saponins. They have been shown to inhibit platelet aggregation, increase cerebral blood flow, improve neurological behavior, decrease infarct volum...The main active components extracted from Panax notoginseng are total saponins. They have been shown to inhibit platelet aggregation, increase cerebral blood flow, improve neurological behavior, decrease infarct volume and promote proliferation and differentiation of neural stem cells in the hippocampus and lateral ventricles. However, there is a lack of studies on whether total saponins of Panax notoginsertg have potential benefits on immature neuroblasts in the olfactory bulb following ischemia and reperfusion. This study established a rat model of global cerebral ischemia and reperfusion using four-vessel occlusion. Rats were administered total sa- ponins of Panax notoginseng at 75 mg/kg intraperitoneally 30 minutes after ischemia then once a day, for either 7 or 14 days. Total saponins of Panax notoginseng enhanced the number of dou- blecortin （DCX）＋ neural progenitor ceils and increased co-localization of DCX with neuronal nuclei and phosphorylated cAMP response element-binding/DCX＋ neural progenitor cells in the olfactory bulb at 7 and 14 days post ischemia. These findings indicate that following global brain ischemia/reperfusion, total saponins of Panax notoginseng promote differentiation of DCX＋ cells expressing immature neuroblasts in the olfactory bulb and the underlying mechanism is related to the activation of the signaling pathway of cyclic adenosine monophosphate response element binding protein.展开更多
基金supported by the Science and Technology Project of Guangdong Province, China (Grant No. 2020B010190001)the National Natural Science Foundation of China (Grant No. 12434016)the National Key Research and Development Program of China (Grant No. 2018YFA0306200)。
文摘Infrared(IR) optics have garnered significant attention due to growing demands in advanced optical imaging,communication, detection, and sensing. Among various IR devices, microlenses and microlens arrays offer distinct advantages in integration capability, imaging precision, multifunctionality, and cost-effective manufacturing. We present a novel design of high-resolution achromatic microlens in the mid-IR region. Different from traditional high-refractive-index convex microlenses embedded within a low-index background medium, the current design is a low-index air concave microlens embedded within a high-index silicon medium. The designed air microlens exhibits capabilities in high-resolution imaging(~λ/6) and achromatic performance across the 3–5 μm mid-IR spectrum. The air microlens could be assembled in large-area microlens arrays or as part of multi-lens system.When combined with the HgCdTe detector system placed on the focal plane, the air microlens can find promising applications in high-resolution optical imaging and high-sensitivity photoelectric detection.
基金supported by the Science and Technology Project of Guangdong Province,China(Grant No.2020B010190001)the National Natural Science Foundation of China(Grant No.12434016)the National Funded Postdoctoral Researcher Program(Grant No.GZB20240785).
文摘When a pump laser beam strikes the surface of a nonlinear crystal with modulated second-order nonlinearity,various nonlinear diffraction phenomena occur,with nonlinear Raman–Nath diffraction(NRND)being a prominent example.In this study,we use an 800-nm Ti:sapphire femtosecond laser beam to pump the surface of a periodically poled lithium niobate(PPLN)crystal thin-plate nonlinear grating.By rotating the crystal,we change the incidence angle and observe and measure the exit angle,polarization,and power of NRND spots on the other side of the crystal.The experiment shows that NRND characteristics are highly sensitive to the incidence angle of the pump laser beam,which are consistent with the theoretical prediction.We expect that this research will advance the understanding of nonlinear diffraction and provide valuable insights for nonlinear optical interaction in complicated geometric and physical configurations.
基金Project supported by Science and Technology Project of Guangdong(Grant No.2020B010190001)the National Natural Science Foundation of China(Grant No.12434016)National Funded Postdoctoral Researcher Program(Grant No.GZB20240785)。
文摘When a laser beam is incident on a nonlinear grating with a laterally modulated second-order nonlinear coefficient,nonlinear diffraction of the noncollinear second-harmonic generation(SHG)signal occurs,with Raman–Nath nonlinear diffraction(NRND)being a prominent example.As these SHG NRND processes involve coupling between the fundamental-wave pump laser vectorial field and the SHG laser vectorial field through the second-order nonlinearity secondrank tensor of the nonlinear crystal,the nonlinear interaction between light and the nonlinear grating can be manipulated by adjusting the polarization state of the pump laser.In this paper,we derive the relationship between the polarization state of the incident light and the generated nonlinear diffraction signal based on the nonlinear coupled wave equation and experimentally validate the predicted diffraction characteristics.The results show that the optical properties of each order of NRND are highly sensitive to the polarization angle of the incident pump laser beam.
基金supported by the Fundamental Research Funds for the Central Universities(Grant No.2022YQLX01)the Fund from the State Key Laboratory of Computational Physics(Grant No.6142A05QN23009)the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDA 25051000).
文摘Rayleigh-Taylor instability(RTI)of finite-thickness shell significantly impacts shell deformation and material mixing processes,with crucial implications for inertial confinement fusion(ICF).This study focuses on the RTI growth at the dual interfaces of a thin shell.A second-order weakly nonlinear(WN)analytical theory is developed to investigate the nonlinear deformation of the shell induced by different perturbation wavelengths initially imposed at the upper and lower interfaces.The validity of the theoretical results within the WN regime has been confirmed via two-dimensional Eulerian numerical simulations.Due to the interface coupling effect,the initially imposed single-mode perturbations at the upper and lower interfaces progressively evolve,exhibiting characteristics typical of multi-mode perturbations.When the initial perturbation wavelengths differ significantly,the primary structure of RTI retains its integrity,a behavior attributed to the dominance of long-wavelength perturbations.For comparable initial wavelengths,mode-coupling significantly distorts the bubble-spike structure in RTI,with the thin shell becoming prone to rupture due to enhanced nonlinear interactions.
文摘Recent clinical and experimental studies have confirmed the effects of Xinfuli Granule (XG), a compound Chinese medicine in the prevention and treatment of heart failure (HF). This study aimed to investigate the effects and the mechanisms of XG on ventricular reconstruction in rats with acute myocardial infarction (AMI).MethodsSprague-Dawley rats were subjected to left anterior descending branch ligation. The rats that survived 24 h were randomly assigned to five groups: medium-dose of XG group (MI+XGM), high-dose of XG group (MI+XGH), carvedilol group (MI+C), medium-dose of XG + carvedilol group (MI+C+XGM). Fourteen rats underwent identical surgical procedures without artery ligation, serving as sham controls. At 28 days, left ventricular weight to body weight (LVW/BW) and heart weight to body weight (HW/BW) were calculated; left ventricular ejection fraction (LVEF), left ventricular shortening fraction (LVFS), left ventricular internal diameter at systole (LVIDS) were measured by ultrasound; HE staining, Masson staining, and Sirius red staining were used to assess the myocardial pathological and physiological changes as well as myocardial fibrosis area and non-infarct zone I/III collagen ratio. Expression of Smad3 were detected and analyzed by Western blot, immunohistochemistry and immunofluorescence. P-Smad3, Smad2 and Smad7 in the TGF-β/Smads signaling pathway were also analyzed by Western blot.ResultsThe LVIDS (P < 0.01), HW/BW (P < 0.05), type I/III collagen ratio (P < 0.01) and myocardial collagen (P < 0.01) decreased significantly while the LVW/BW, LVFS (P < 0.05) increased significantly in MI+XGM group as compared with those in other groups. The expression of key signal molecules of the TGF-β/Smads signaling pathway, including Smad3, P-Smad3 and Smad2 protein were decreased, while the expression of Smad7 increased in both XG and carvedilol treatment groups as compared to those of the MI group (all P < 0.01). Immunohistochemistry and immunofluorescence further confirmed the down-regulated Smad3 expression.ConclusionXG can improve ventricular reconstruction and inhibit myocardial fibrosis in rats with AMI by regulating TGF-β/Smads signaling pathway.
基金the National Natural Science Foundation of China(No.51471182)this work is also supported by Shanghai international science and Technology Cooperation Fund(No.17520711700)the National Key Research and Development Project(No.2017YFB0310600).
文摘The current COVID-19 pandemic urges the extremely sensitive and prompt detection of SARS-CoV-2 virus.Here,we present a Human Angiotensin-converting-enzyme 2(ACE2)-functionalized gold“virus traps”nanostructure as an extremely sensitive SERS biosensor,to selectively capture and rapidly detect S-protein expressed coronavirus,such as the current SARS-CoV-2 in the contaminated water,down to the single-virus level.Such a SERS sensor features extraordinary 106-fold virus enrichment originating from high-affinity of ACE2 with S protein as well as“virus-traps”composed of oblique gold nanoneedles,and 109-fold enhancement of Raman signals originating from multi-component SERS effects.Furthermore,the identification standard of virus signals is established by machine-learning and identification techniques,resulting in an especially low detection limit of 80 copies mL^(−1) for the simulated contaminated water by SARS-CoV-2 virus with complex circumstance as short as 5 min,which is of great significance for achieving real-time monitoring and early warning of coronavirus.Moreover,here-developed method can be used to establish the identification standard for future unknown coronavirus,and immediately enable extremely sensitive and rapid detection of novel virus.
基金Project supported by Guangdong Provincial Innovative and Entrepreneurial Research Team Program(Grant No.2016ZT06C594)the Science and Technology Project of Guangdong Province,China(Grant No.2020B010190001)the National Key Research and Development Programof China(Grant No.2018YFA 0306200).
文摘Topological photonic states(TPSs)as a new type of waveguide state with one-way transport property can resist backscattering and are impervious to defects,disorders and metallic obstacles.Gyromagnetic photonic crystal(GPC)is the first artificial microstructure to implement TPSs,and it is also one of the most important platforms for generating truly one-way TPSs and exploring their novel physical properties,transport phenomena,and advanced applications.Herein,we present a brief review of the fundamental physics,novel properties,and practical applications of TPSs based on GPCs.We first examine chiral one-way edge states existing in uniformly magnetized GPCs of ordered and disordered lattices,antichiral one-way edge states in cross magnetized GPCs,and robust one-way bulk states in heterogeneously magnetized GPCs.Then,we discuss the strongly coupling effect between two co-propagating(or counter-propagating)TPSs and the resulting physical phenomena and device applications.Finally,we analyze the key issues and prospect the future development trends for TPSs in GPCs.The purpose of this brief review is to provide an overview of the main features of TPSs in GPC systems and offer a useful guidance and motivation for interested scientists and engineers working in related scientific and technological areas.
基金financially supported by the projects of China Geological Survey(DD20221695,DD20160346 and DD20190379)the Fundamental Research Funds of the Central Public Welfare Scientific Research Institutes(JYYWF20183701 and JYYWF20183704)the Inner Mongolia Geological Exploration Fund Project(2020-YS03).
文摘By the end of 2020,83 silver deposits(or ore occurrences),including four super-large-scale deposits,nine large-scale deposits,33 medium-scale deposits and 37 small-scale deposits or ore occurrences,have been proved.The amount of silver metal exceeds 86000 t with average grade of 100 g/t,which makes Daxing’anling region one of the the most important silver ore belt in China.However,the metallogenic characteristics and metallogenesis need to be clarified.The silver deposits in the study area are classified into three main types,which are magmatic hydrothermal vein type,continental volcano-subvolcanic type and skarn type,respectively.The supergiant deposits include the Shuangjianzishan deposit(silver metal amount of 15214 t with average grade of 138 g/t),the Baiyinchagandongshan deposit(silver metal amount of 9446 t with average grade of 187 g/t),the Huaobaote deposit(silver metal amount of 6852 t with average grade of 170 g/t),and the Fuxingtun deposit(silver metal amount of 5240 t with average grade of 196 g/t).The silver deposits are mainly distributed in the central and south of the Daxing’anling area,and mainly formed in the Yanshanian period.The silver polymetallic deposits in the Daxinganling area are significantly controlled by regional faults and the junction zone of volcanic rock basins and their margins.The north-east trending deep faults are the most important ore-controlling structures in this area.The distribution of silver polymetallic deposits along the main faults is obvious,and the intersection area of multiple groups of faults often form important mine catchments.The Permian is the most important ore-bearing formation in this area,but some important silver polymetallic deposits occur in Mesozoic volcanic basins or pre-Mesozoic strata.The magmatic rocks related to mineralization are mainly intermediate acidic or acidic intrusions,intermediate acidic lavas,pyroclastic rocks,and small intrusions of ultra-shallow or shallow facies of the Yanshanian Period.The mineralization element combination is mainly determined by the elemental geochemical background of surrounding rocks or source layers.In addition,the type of deposit,the distance from the mineralization center,and the degree of differentiation of ore-forming rock mass are also important influence factors.The article analyzes the prospecting prospects of each silver deposit type in the study area,discusses the relationship between mineralization center and deep prospecting,and proposes that porphyry silver deposits should be paid attention to.In the prospecting and exploration of silver deposits,comprehensive evaluation and multi-target prospecting need to be strengthened because silver can coexist or be associated with a variety of metals.
基金the National Natural Science Foundation of China under Grant Nos.11575033,11675026 and 11975053the CAEP Foundation under Grant No.CX2019033.
文摘Taking the long-wavelength Rayleigh-Taylor instability(RTI) on the thin shell of inertial confinement fusion as the research object,a linear analytical model is presented to study the phase effects that are caused by the phase difference of single-mode perturbations on the two interfaces.Its accuracy is tested by numerical simulations.By analyzing the characteristic of this model,it is found that the phase difference does not change the basic RTI structure(only one spike and one bubble in a period).However,the symmetry of the spike and bubble is destroyed,which has non-expected influences on the convergent motion of ICF targets.Meanwhile,the phenomenon that the distance between spikes and bubbles along the vertical direction of acceleration differs by π is demonstrated.It is also shown that when the phase difference is large,the temporal evolution of the RTI is more serious and the thin target is easier to tend to break.
基金the National Natural Science Foundation of China(11974119)Science and Technology Project of Guangdong(2020B010190001)+1 种基金Guangdong Innovative and Entrepreneurial Research Team Program(2016ZT06C594)National Key R&D Program of China(2018YFA 0306200).
文摘Antichiral gyromagnetic photonic crystal(GPC)in a honeycomb lattice with the two interpenetrating triangular sublattices A and B magnetically biased in opposite directions can realize antichiral one-way edge states propagating along the same direction at its two parallel edges.Here,we report the construction and observation of topological beam splitting with the easily adjustable right-to-left ratio in an antichiral GPC.The splitter is compact and configurable,has high trans-mission efficiency,and allows for multi-channel utilization,crosstalk-proof,and robust against defects and obstacles.This magnificent performance is attributed to the peculiar property that antichiral one-way edge states exist only at zigzag edge but not at armchair edge of antichiral GPC.When we combine two rectangular antichiral GPCs holding left-and right-propagating antichiral one-way edge states respectively,bidirectionally radiating one-way edge states at two paral-lel zigzag edges can be achieved.Our observations can enrich the understanding of fundamental physics and expand to-pological photonic applications.
基金Project supported by the National Key Research and Development Program of China(Grant No.2018YFA0306200)the National Natural Science Foundation of China(Grant No.11974119)Guangdong Provincial Innovative and Entrepreneurial Research Team Program,China。
文摘The strongly coupled system composed of atoms,molecules,molecule aggregates,and semiconductor quantum dots embedded within an optical microcavity/nanocavity with high quality factor and/or low modal volume has become an excellent platform to study cavity quantum electrodynamics(CQED),where a prominent quantum effect called Rabi splitting can occur due to strong interaction of cavity-mode single-photon with the two-level atomic states.In this paper,we build a new quantum model that can describe the optical response of the strongly-coupled system under the action of an external probing light and the spectral lineshape.We take the Hamiltonian for the strongly-coupled photon-atom system as the unperturbed Hamiltonian H_(0)and the interaction Hamiltonian of the probe light upon the coupled-system quantum states as the perturbed Hamiltonian V.The theory yields a double Lorentzian lineshape for the permittivity function,which agrees well with experimental observation of Rabi splitting in terms of spectral splitting.This quantum theory will pave the way to construct a complete understanding for the microscopic strongly-coupled system that will become an important element for quantum information processing,nano-optical integrated circuits,and polariton chemistry.
基金Project supported by the National Key Research and Development Program of China(Grant No.2018YFA 0306200)the National Natural Science Foundation of China(Grant No.11974119)+1 种基金the Science and Technology Project of Guangdong Province,China(Grant No.2020B010190001)the Guangdong Innovative and Entrepreneurial Research Team Program(Grant No.2016ZT06C594)。
文摘Birefringence production of light by natural birefringent crystal has long been studied and well understood.Here,we develop a simple and comprehensive rigorous electromagnetic theory that allows one to build up the complete picture about the optics of crystals in a friendly way.This theory not only yields the well-known refraction angle and index of ellipse for birefringence crystal,but also discloses many relevant physical and optical quantities that are rarely studied and less understood.We obtain the reflection and transmission coefficient for amplitude and intensity of light at the crystal surface under a given incident angle and show the electromagnetic field distribution within the crystal.We derive the wavefront and energy flux refraction angle of light and the corresponding phase and ray refractive index.We find big difference between them,where the phase refractive index satisfies the classical index of ellipse and Snell’s law,while the ray refractive index does not.Moreover,we disclose the explicit expressions for the zero-reflection Brewster angle and the critical angle for total internal reflection.For better concept demonstration,we take a weak birefringent crystal of lithium niobate and a strong birefringent crystal tellurium as examples and perform simple theoretical calculations.In addition,we perform experimental measurement upon z-cut lithium niobate plate and find excellent agreement between theory and experiment in regard to the Brewster angle.Our theoretical and experimental results can help to construct a clear and complete picture about light transport characteristics in birefringent crystals,and may greatly facilitate people to find rigorous solution to many light-matter interaction processes happening within birefringent crystals,e.g.,nonlinear optical interactions,with electromagnetic theory.
基金National Natural Science Foundation of China under Grant Nos.11575033,11675026,and 11975053.
文摘The Rayleigh-Taylor instability at the weakly nonlinear(WN)stage in spherical geometry is studied by numerical simulation.The mode coupling processes are revealed.The results are consistent with the WN model based on parameter expansion,while higher order effects are found to be non-negligible.For Legendre mode perturbation Pn(cos B),the nonlinear saturation amplitude(NSA)of the fundamental mode decreases with the mode number n.When n is large,the spherical NSA is lower than the corresponding planar one.However,for large n,the planar NSA can be recovered by applying Fourier transformation to the bubble/spike near the equator and calculating the NSA of the converted trigonometric harmonic.
基金Supported by the National Natural Science Foundation of China(Grant Nos.11575033,11675026,and 11975053)。
文摘Interface width effect on the spherical Rayleigh–Taylor instability in the weakly nonlinear regime is studied by numerical simulations.For Legendre perturbation mode Pn with wave number Kn and interface half-width L,the commonly adopted empirical linear growth rate formulaγnem(L)=γn/√1+KnL is found to be sufficient in spherical geometry.At the weakly nonlinear stage,the interface width affects the mode coupling processes.The development of the mode P2n is substantially influenced by the interface width.Moreover,the nonlinear saturation amplitude increases with the interface width.
基金supported by the Science and Technology Project of Guangdong (Grant No.2020B010190001)the National Natural Science Foundation of China (Grant No.11974119)+1 种基金the Guangdong Innovative and Entrepreneurial Research Team Program (Grant No.2016ZT06C594)the National Key R&D Program of China (Grant No.2018YFA 0306200).
文摘A supercontinuum white laser with ultrabroad bandwidth,intense pulse energy,and high spectral flatness can be accomplished via synergic action of third-order nonlinearity(3rd-NL)and second-order nonlinearity.In this work,we employ an intense Ti:sapphire femtosecond laser with a pulse duration of 50 fs and pulse energy up to 4 mJ to ignite the supercontinuum white laser.Remarkably,we use water instead of the usual solid materials as the 3rd-NL medium exhibiting both strong self-phase modulation and stimulated Raman scattering effect to create a supercontinuum laser with significantly broadened bandwidth and avoid laser damage and destruction.Then the supercontinuum laser is injected into a water-embedded chirped periodically poled lithium niobate crystal that enables broadband and high-efficiency second-harmonic generation.The output white laser has a 10 dB bandwidth encompassing 413 to 907 nm,more than one octave,and a pulse energy of 0.6 mJ.This methodology would open up an efficient route to creating a long-lived,high-stability,and inexpensive white laser with intense pulse energy,high spectral flatness,and ultrabroad bandwidth for application to various areas of basic science and high technology.
基金financial support from Science and Technology Project of Guangdong(2020B010190001)National Natural Science Foundation(12434016).
文摘Raman spectroscopy offers a great power to detect,analyze and identify molecules,and monitor their temporal dynamics and evolution when combined with single-molecule surface-enhanced Raman scattering(SM-SERS)substrates.Here we present a SM-SERS scheme that involves simultaneously giant chemical enhancement from WS22D materials,giant electromagnetic enhancement from plasmonic nanogap hot spot,and inhibition of molecular fluorescence influence under near-infrared laser illumination.Remarkably we find Coulomb attraction between analyte and gold nanoparticle can trigger spontaneous formation of molecule-hotspot pairing with high precision,stability and robustness.The scheme has enabled realization of universal,robust,fast,and large-scale uniform SM-SERS detection for three Raman molecules of rhodamine B,rhodamine 6G,and crystal violet with a very low detection limit of 10−16 M and at a very fast spectrum acquisition time of 50 ms.
基金supported by the National Natural Science Foundation of China(Grant Nos.12434016 and 12474380)Science and Technology Project of Guangdong Province(Grant No.2020B0101-90001)+1 种基金the National Key Research and Development Program of China(Grant No.2023YFA1406900)the Natural Science Foundation of Guangdong Province(Grant No.2025A1515010714)。
文摘Spin-momentum locking is widely regarded as an inherent property of evanescent waves,where the transverse spin angular momentum is intrinsically tied to the wave's polarization.This principle is well established in systems such as surface plasmon polaritons,surface elastic waves,and other evanescent modes.Here,we theoretically unveil an anomalous breakdown of spin-momentum locking in evanescent electromagnetic waves at a metalgyromagnetic interface.We show that the hybrid polarization of the field induces two successive reversals of transverse spin near the interface—directly violating the conventional locking between spin and momentum.As a result,identical chiral sources placed at different heights above the interface excite evanescent waves propagating in opposite directions,defying standard expectations.This discovery challenges the presumed universality of spin-momentum locking and opens new degrees of freedom for controlling wave propagation in photonic and plasmonic systems.
基金supported by the Hunan Provincial Innovation Foundation for Postgraduate in China,No.CX2014B099(to XH)the Science Foundation of Hunan Provincial Education Department of China,No.11C1264(to FJD),13C958(to XH)
文摘The main active components extracted from Panax notoginseng are total saponins. They have been shown to inhibit platelet aggregation, increase cerebral blood flow, improve neurological behavior, decrease infarct volume and promote proliferation and differentiation of neural stem cells in the hippocampus and lateral ventricles. However, there is a lack of studies on whether total saponins of Panax notoginsertg have potential benefits on immature neuroblasts in the olfactory bulb following ischemia and reperfusion. This study established a rat model of global cerebral ischemia and reperfusion using four-vessel occlusion. Rats were administered total sa- ponins of Panax notoginseng at 75 mg/kg intraperitoneally 30 minutes after ischemia then once a day, for either 7 or 14 days. Total saponins of Panax notoginseng enhanced the number of dou- blecortin （DCX）＋ neural progenitor ceils and increased co-localization of DCX with neuronal nuclei and phosphorylated cAMP response element-binding/DCX＋ neural progenitor cells in the olfactory bulb at 7 and 14 days post ischemia. These findings indicate that following global brain ischemia/reperfusion, total saponins of Panax notoginseng promote differentiation of DCX＋ cells expressing immature neuroblasts in the olfactory bulb and the underlying mechanism is related to the activation of the signaling pathway of cyclic adenosine monophosphate response element binding protein.
