Background Promoting the synchronization of glucose and amino acid release in the digestive tract of pigs could effectively improve dietary nitrogen utilization.The rational allocation of dietary starch sources and th...Background Promoting the synchronization of glucose and amino acid release in the digestive tract of pigs could effectively improve dietary nitrogen utilization.The rational allocation of dietary starch sources and the exploration of appropriate dietary glucose release kinetics may promote the dynamic balance of dietary glucose and amino acid supplies.However,research on the effects of diets with different glucose release kinetic profiles on amino acid absorption and portal amino acid appearance in piglets is limited.This study aimed to investigate the effects of the kinetic pattern of dietary glucose release on nitrogen utilization,the portal amino acid profile,and nutrient transporter expression in intestinal enterocytes in piglets.Methods Sixty-four barrows(15.00±1.12 kg)were randomly allotted to 4 groups and fed diets formulated with starch from corn,corn/barley,corn/sorghum,or corn/cassava combinations(diets were coded A,B,C,or D respectively).Protein retention,the concentrations of portal amino acid and glucose,and the relative expression of amino acid and glucose transporter m RNAs were investigated.In vitro digestion was used to compare the dietary glucose release profiles.Results Four piglet diets with different glucose release kinetics were constructed by adjusting starch sources.The in vivo appearance dynamics of portal glucose were consistent with those of in vitro dietary glucose release kinetics.Total nitrogen excretion was reduced in the piglets in group B,while apparent nitrogen digestibility and nitrogen retention increased(P<0.05).Regardless of the time(2 h or 4 h after morning feeding),the portal total free amino acids content and contents of some individual amino acids(Thr,Glu,Gly,Ala,and Ile)of the piglets in group B were significantly higher than those in groups A,C,and D(P<0.05).Cluster analysis showed that different glucose release kinetic patterns resulted in different portal amino acid patterns in piglets,which decreased gradually with the extension of feeding time.The portal His/Phe,Pro/Glu,Leu/Val,Lys/Met,Tyr/Ile and Ala/Gly appeared higher similarity among the diet treatments.In the anterior jejunum,the glucose transporter SGLT1 was significantly positively correlated with the amino acid transporters B0AT1,EAAC1,and CAT1.Conclusions Rational allocation of starch resources could regulate dietary glucose release kinetics.In the present study,group B(corn/barley)diet exhibited a better glucose release kinetic pattern than the other groups,which could affect the portal amino acid contents and patterns by regulating the expression of amino acid transporters in the small intestine,thereby promoting nitrogen deposition in the body,and improving the utilization efficiency of dietary nitrogen.展开更多
Recent advancements in robotics have transformed industries such as manufacturing,logistics,surgery,and planetary exploration.A key challenge is developing efficient motion planning algorithms that allow robots to nav...Recent advancements in robotics have transformed industries such as manufacturing,logistics,surgery,and planetary exploration.A key challenge is developing efficient motion planning algorithms that allow robots to navigate complex environments while avoiding collisions and optimizing metrics like path length,sweep area,execution time,and energy consumption.Among the available algorithms,sampling-based methods have gained the most traction in both research and industry due to their ability to handle complex environments,explore free space,and offer probabilistic completeness along with other formal guarantees.Despite their widespread application,significant challenges still remain.To advance future planning algorithms,it is essential to review the current state-of-the-art solutions and their limitations.In this context,this work aims to shed light on these challenges and assess the development and applicability of sampling-based methods.Furthermore,we aim to provide an in-depth analysis of the design and evaluation of ten of the most popular planners across various scenarios.Our findings highlight the strides made in sampling-based methods while underscoring persistent challenges.This work offers an overview of the important ongoing research in robotic motion planning.展开更多
With the ever-increasing number of natural disasters warning documents in document databases, the document database is becoming an economic and efficient way for enterprise staffs to learn and understand the contents ...With the ever-increasing number of natural disasters warning documents in document databases, the document database is becoming an economic and efficient way for enterprise staffs to learn and understand the contents of the natural disasters warning through searching for necessary text documents. Generally, the document database can recommend a mass of documents to the enterprise staffs through analyzing the enterprise staff's precisely typed keywords. In fact, these recommended documents place a heavy burden on the enterprise staffs to learn and select as the enterprise staffs have little background knowledge about the contents of the natural disasters warning. Thus, the enterprise staffs fail to retrieve and select appropriate documents to achieve their desired goals.Considering the above drawbacks, in this paper, we propose a fuzzy keywords-driven Natural Disasters Warning Documents retrieval approach(named NDWDkeyword). Through the text description mining of documents and the fuzzy keywords searching technology, the retrieval approach can precisely capture the enterprise staffs' target requirements and then return necessary documents to the enterprise staffs. Finally, a case study is run to explain our retrieval approach step by step and demonstrate the effectiveness and feasibility of our proposal.展开更多
基金partially supported by the National Key Research and Development Program of China(2021YFD1300201)Jilin Province Key Research and Development Program of China(20220202044NC)。
文摘Background Promoting the synchronization of glucose and amino acid release in the digestive tract of pigs could effectively improve dietary nitrogen utilization.The rational allocation of dietary starch sources and the exploration of appropriate dietary glucose release kinetics may promote the dynamic balance of dietary glucose and amino acid supplies.However,research on the effects of diets with different glucose release kinetic profiles on amino acid absorption and portal amino acid appearance in piglets is limited.This study aimed to investigate the effects of the kinetic pattern of dietary glucose release on nitrogen utilization,the portal amino acid profile,and nutrient transporter expression in intestinal enterocytes in piglets.Methods Sixty-four barrows(15.00±1.12 kg)were randomly allotted to 4 groups and fed diets formulated with starch from corn,corn/barley,corn/sorghum,or corn/cassava combinations(diets were coded A,B,C,or D respectively).Protein retention,the concentrations of portal amino acid and glucose,and the relative expression of amino acid and glucose transporter m RNAs were investigated.In vitro digestion was used to compare the dietary glucose release profiles.Results Four piglet diets with different glucose release kinetics were constructed by adjusting starch sources.The in vivo appearance dynamics of portal glucose were consistent with those of in vitro dietary glucose release kinetics.Total nitrogen excretion was reduced in the piglets in group B,while apparent nitrogen digestibility and nitrogen retention increased(P<0.05).Regardless of the time(2 h or 4 h after morning feeding),the portal total free amino acids content and contents of some individual amino acids(Thr,Glu,Gly,Ala,and Ile)of the piglets in group B were significantly higher than those in groups A,C,and D(P<0.05).Cluster analysis showed that different glucose release kinetic patterns resulted in different portal amino acid patterns in piglets,which decreased gradually with the extension of feeding time.The portal His/Phe,Pro/Glu,Leu/Val,Lys/Met,Tyr/Ile and Ala/Gly appeared higher similarity among the diet treatments.In the anterior jejunum,the glucose transporter SGLT1 was significantly positively correlated with the amino acid transporters B0AT1,EAAC1,and CAT1.Conclusions Rational allocation of starch resources could regulate dietary glucose release kinetics.In the present study,group B(corn/barley)diet exhibited a better glucose release kinetic pattern than the other groups,which could affect the portal amino acid contents and patterns by regulating the expression of amino acid transporters in the small intestine,thereby promoting nitrogen deposition in the body,and improving the utilization efficiency of dietary nitrogen.
基金support by the Bavarian State Ministry for Economic Affairs,Regional Development and Energy(StMWi)for the Lighthouse Initiative KI.FABRIK(Phase 1:Infrastructure and the research and development program under grant no.DIK0249).
文摘Recent advancements in robotics have transformed industries such as manufacturing,logistics,surgery,and planetary exploration.A key challenge is developing efficient motion planning algorithms that allow robots to navigate complex environments while avoiding collisions and optimizing metrics like path length,sweep area,execution time,and energy consumption.Among the available algorithms,sampling-based methods have gained the most traction in both research and industry due to their ability to handle complex environments,explore free space,and offer probabilistic completeness along with other formal guarantees.Despite their widespread application,significant challenges still remain.To advance future planning algorithms,it is essential to review the current state-of-the-art solutions and their limitations.In this context,this work aims to shed light on these challenges and assess the development and applicability of sampling-based methods.Furthermore,we aim to provide an in-depth analysis of the design and evaluation of ten of the most popular planners across various scenarios.Our findings highlight the strides made in sampling-based methods while underscoring persistent challenges.This work offers an overview of the important ongoing research in robotic motion planning.
文摘With the ever-increasing number of natural disasters warning documents in document databases, the document database is becoming an economic and efficient way for enterprise staffs to learn and understand the contents of the natural disasters warning through searching for necessary text documents. Generally, the document database can recommend a mass of documents to the enterprise staffs through analyzing the enterprise staff's precisely typed keywords. In fact, these recommended documents place a heavy burden on the enterprise staffs to learn and select as the enterprise staffs have little background knowledge about the contents of the natural disasters warning. Thus, the enterprise staffs fail to retrieve and select appropriate documents to achieve their desired goals.Considering the above drawbacks, in this paper, we propose a fuzzy keywords-driven Natural Disasters Warning Documents retrieval approach(named NDWDkeyword). Through the text description mining of documents and the fuzzy keywords searching technology, the retrieval approach can precisely capture the enterprise staffs' target requirements and then return necessary documents to the enterprise staffs. Finally, a case study is run to explain our retrieval approach step by step and demonstrate the effectiveness and feasibility of our proposal.
