Human enterovirus A71(EV-A71)is a major causative agent of hand,foot and mouth disease(HFMD),which poses a significant public health threat,particularly among young children.Mitochondrial antiviral signaling protein(M...Human enterovirus A71(EV-A71)is a major causative agent of hand,foot and mouth disease(HFMD),which poses a significant public health threat,particularly among young children.Mitochondrial antiviral signaling protein(MAVS)and interferon regulatory factor 3(IRF3)are vital proteins for the induction of type I interferons(IFN-I)and downstream interferon-stimulated genes(ISGs)during EVA71 infection.While posttranslational modifications are known to critically influence viral infection processes,the mechanisms by which EV-A71 exploits host deubiquitinases(DUBs)for immune evasion remain poorly understood.In this study,we demonstrated that EV-A71 infection upregulated ubiquitinspecific protease 5(USP5)expression.Knockdown of USP5 not only inhibited EV-A71 replication but also observably increased the production of IFN-I and ISGs.Furthermore,USP5 also regulated the replication of EV-D68 and CVA16 and the production of IFN-I and ISGs.Mechanistically,USP5 physically interacted with MAVS and IRF3 and reduced the K63-linked polyubiquitination of MAVS and IRF3.Conversely,USP5 knockdown increased the K63-linked polyubiquitination of MAVS and IRF3,thereby accelerating the phosphorylation of IRF3 and increasing IFN-I production during EV-A71 infection.Furthermore,pharmacological inhibition of USP5 with the small-molecule inhibitor PR-619 significantly potentiated the antiviral effects of IFN against EV-A71.Collectively,our findings reveal a previously unrecognized role of USP5 in facilitating EV-A71 immune evasion by dampening MAVSand IRF3-mediated antiviral signaling.These insights provide a novel therapeutic avenue for combating EV-A71 infection through targeted modulation of the USP5-IRF3 axis.展开更多
Ocean mining activities have been ongoing for nearly 70 years,making great contributions to industrialization.Given the increasing demand for energy,along with the restructuring of the energy supply catalyzed by effor...Ocean mining activities have been ongoing for nearly 70 years,making great contributions to industrialization.Given the increasing demand for energy,along with the restructuring of the energy supply catalyzed by efforts to achieve a low-carbon economy,deep seabed mining will play an important role in addressing energy-and resource-related problems in the future.However,deep seabed mining remains in the exploratory stage,with many challenges presented by the high-pressure,low-temperature,and complex geologic and hydrodynamic environments in deep-sea mining areas,which are inaccessible to human activities.Thus,considerable efforts are required to ensure sustainable,economic,reliable,and safe deep seabed mining.This study reviews the latest advances in marine engineering geology and the environment related to deep-sea min-ing activities,presents a bibliometric analysis of the development of ocean mineral resources since the 1950s,summarizes the development,theory,and issues related to techniques for the three stages of ocean mining(i.e.,exploration,extraction,and closure),and discusses the engineering geology environment,geological disasters,in-situ monitoring techniques,envi-ronmental protection requirements,and environmental effects in detail.Finally,this paper gives some key conclusions and future perspectives to provide insights for subsequent studies and commercial mining operations.展开更多
Because of their high capacity and low potential,lithium metal anodes are considered to be promising candidates for next generation electrode materials.However,the safety concerns and limited cycling life associated w...Because of their high capacity and low potential,lithium metal anodes are considered to be promising candidates for next generation electrode materials.However,the safety concerns and limited cycling life associated with uncontrollable dendrite growth hamper practical applications.In this work,the acidified cellulose ester,which is a mixed fiber microporous membrane film,was used as a novel electrolyte additive that effectively improves the cycle stability of the lithium metal anode and inhibits dendrite growth.The focus of this paper is on inhibiting the formation and growth of lithium dendrites.The coulombic efficiency of a Li|Cu battery with this acidified cellulose ester additive remains stable at 99%after 500 cycles under a current density of 1 mA/cm^2.Symmetric batteries also remain stable after 500 cycles(1000 h)under a current density of 1 mA/cm^2.These superior properties can be ascribed to the induced nucleation and the uniform distribution of lithium ion flux.This study uncovers an approach for effectively enabling stable cycling of dendrite-free lithium metal anodes.展开更多
Highly accurate closed-form eigensolutions for flutter of three-dimensional(3D)panel with arbitrary combinations of simply supported(S),glide(G),clamped(C)and free(F)boundary conditions(BCs),such as cantilever panels,...Highly accurate closed-form eigensolutions for flutter of three-dimensional(3D)panel with arbitrary combinations of simply supported(S),glide(G),clamped(C)and free(F)boundary conditions(BCs),such as cantilever panels,are achieved according to the linear thin plate theory and the first-order piston theory as well as the complex modal analysis,and all solutions are in a simple and explicit form.The iterative Separation-of-Variable(iSOV)method proposed by the pre-sent authors is employed to obtain the highly accurate eigensolutions.The flutter mechanism is studied with the benefit of eigenvalue properties from mathematical senses.The effects of boundary conditions,chord-thickness ratios,aerodynamic damping,aspect ratios and in-plane loads on flut-ter properties are examined.The results are compared with those of Kantorovich method and Galerkin method,and also coincide well with analytical solutions in literature,verifying the accu-racy of the present closed-form results.It is revealed that,(A)the flutter characteristics are domi-nated by the cross section properties of panels in the direction of stream flow;(B)two types of flutter,called coupled-mode flutter and zero-frequency flutter which includes zero-frequency single-mode flutter and buckling,are observed;(C)boundary conditions and in-plane loads can affect both flutter boundary and flutter type;(D)the flutter behavior of 3D panel is similar to that of the two-dimensional(2D)panel if the aspect ratio is up to a certain value;(E)four to six modes should be used in the Galerkin method for accurate eigensolutions,and the results converge to that of Kantorovich method which uses the same mode functions in the direction perpendicular to the stream flow.The present analysis method can be used as a reference for other stability issues characterized by complex eigenvalues,and the highly closed-form solutions are useful in parameter designs and can also be taken as benchmarks for the validation of numerical methods.展开更多
Due to the uncertainty of renewable energy power generation and the non-linearity of load demand,it becomes complicated to determine the capacity of each device in hybrid renewable energy power generation systems.This...Due to the uncertainty of renewable energy power generation and the non-linearity of load demand,it becomes complicated to determine the capacity of each device in hybrid renewable energy power generation systems.This work aims to optimize the capacity of two types of the off-grid hybrid wind-hydrogen energy system.We considered the maximum profit of the system and the minimum loss of power supply probability as optimization goals.Firstly,we established steady-state models of the wind turbine,alkaline electrolyzer,lead-acid battery,and proton exchange membrane fuel cell in matrix laboratory software to optimize the capacity.Secondly,we analyzed the operating mode of the system and determined two system structures(system contains batteries whether or not).Finally,according to the wind speed and load in the sample area,we compared the economics of the two systems and selected the optimal configuration for the area.In the same calculation example data,the non-dominated sorting genetic algorithm-II(NSGA-II)is used to optimize the capacity of each device in the two systems.The results showed that the profit of the without battery-equipped system is 32.38%higher than another system.But the power supply reliability is the opposite.To avoid the contingency of the calculation results,we used the traditional genetic algorithm(GA)and ant colony optimization(ACO)to calculate the same example.The results showed that NSGA-II is significantly better than GA and ACO in terms of iteration steps and calculation results.The required architecture for the System-I composes of 3 numbers of 10 kW wind turbines,61 sets of 12 V·240 Ah leadacid batteries,8 kW electrolytic cell,and 6 kW PEMFC.The net profit and LPSP are ¥44,315 and 0.01254 respectively.The required architecture for the System-II composes of 2 numbers of 10 kW wind turbines,24 kW electrolytic cells,and 18 kW PEMFC.Net profit and LPSP are ¥58,663 and 0.03244,respectively.This paper provided two schemes for the optimal configuration of the hybrid wind-hydrogen energy system in islanding mode,which provided a theoretical basis for practical engineering applications.展开更多
The spontaneous growth and evolution mechanism of metal whiskers have long been scientific problems.With the development of the integration of electronic and electrical productions,short circuits and system failures a...The spontaneous growth and evolution mechanism of metal whiskers have long been scientific problems.With the development of the integration of electronic and electrical productions,short circuits and system failures are raised by metal whiskers continuously.In the meantime,the related theories and mechanisms of whiskering problem are still vague,leading to a deficiency in the studies of environmental factors influencing the whisker phenomenon.Besides,the extreme environments such as aerospace,have been proven the accelerators to the formation of metal whiskers,resulting in a severe threaten to equipment and devices working in such environments including satellite and military equipment.To establish a comprehensive understanding to the whiskering process associated with their applicable control strategies,this study analyzes the growth phenomenon,influencing factors,formation process and evolution mechanism of metal whiskers in extreme service environments,puts forward the corresponding controlling strategies,offers a reference for the establishment of Chinese extreme aerospace strategic environment,and improves the reliability of aerospace systems.展开更多
With the help of the redox mediator, decoupled water-splitting allows O_(2)and H_(2)to be produced at different times, at different rates, and even in different cells, which promotes both the operation safety and the ...With the help of the redox mediator, decoupled water-splitting allows O_(2)and H_(2)to be produced at different times, at different rates, and even in different cells, which promotes both the operation safety and the utilization of renewable power sources. However, the current densities and stabilities of these redox mediators are commonly low, which require further improvements for practical applications. Here, we propose to use supercapacitors as solid state redox mediators for decoupled water splitting. For demonstration, Na_(0.5)MnO_(2)(pseudocapacitor) and active carbon(double layer capacitor), are both used as the redox mediator. These supercapacitors show superior current density(1 A/cm^(2)) and ultralong cycle-life(8000 cycles) compared with commonly investigated battery-based mediators(NiOOH/Ni(OH)_(2)). Our research proves supercapacitors can be used as redox relay with high current density and stability, which may bring new insights in the design of decoupled water splitting systems.展开更多
Lithium metal batteries(LMBs)are considered the ideal choice for high volumetric energy density lithium-ion batteries,but uncontrolled lithium deposition poses a significant challenge to the stability of such devices....Lithium metal batteries(LMBs)are considered the ideal choice for high volumetric energy density lithium-ion batteries,but uncontrolled lithium deposition poses a significant challenge to the stability of such devices.In this paper,we introduce a 2.5μm-thick asymmetric and ultrastrong separator,which can induce tissue-like lithium deposits.The asymmetric separator,denoted by utPE@Cu_(2)O,was prepared by selective synthesis of Cu_(2)O nanoparticles on one of the outer surfaces of a nanofibrous(diameter~10 nm)ultrastrong ultrahigh molecular weight polyethylene(UHMWPE)membrane.Microscopic analysis shows that the lithium deposits have tissue-like morphology,resulting in the symmetric lithium cells assembled using utPE@Cu_(2)O with symmetric Cu_(2)O coating exhibiting stable performance for over 2000 h of cycling.This work demonstrates the feasibility of a facile approach ultrathin separators for the deployment of lithium metal batteries,providing a pathway towards enhanced battery performance and safety.展开更多
Designing high-performance and low-cost electrocatalysts for oxygen evolu-tion reaction(OER)is critical for the conversion and storage of sustainable energy technologies.Inspired by the biomineralization process,we ut...Designing high-performance and low-cost electrocatalysts for oxygen evolu-tion reaction(OER)is critical for the conversion and storage of sustainable energy technologies.Inspired by the biomineralization process,we utilized the phosphorylation sites of collagen molecules to combine with cobalt-based mononuclear precursors at the molecular level and built a three-dimensional(3D)porous hierarchical material through a bottom-up biomimetic self-assembly strategy to obtain single-atom catalysts confined on carbonized biomimetic self-assembled carriers(Co SACs/cBSC)after subsequent high-temperature annealing.In this strategy,the biomolecule improved the anchoring efficiency of the metal precursor through precise functional groups;meanwhile,the binding-then-assembling strategy also effectively suppressed the nonspecific adsorption of metal ions,ultimately preventing atomic agglomeration and achieving strong electronic metal-support interactions(EMSIs).Experimental characterizations confirm that binding forms between cobalt metal and carbonized self-assembled substrate(Co–O_(4)–P).Theoretical calculations disclose that the local environment changes significantly tailored the Co d-band center,and optimized the binding energy of oxygenated intermediates and the energy barrier of oxygen release.As a result,the obtained Co SACs/cBSC catalyst can achieve remarkable OER activity and 24 h durability in 1 M KOH(η_(10) at 288 mV;Tafel slope of 44 mV dec^(-1)),better than other transition metal-based catalysts and commercial IrO_(2).Overall,we presented a self-assembly strategy to prepare transition metal SACs with strong EMSIs,providing a new avenue for the preparation of efficient catalysts with fine atomic structures.展开更多
Taking an industrial sludge and its preparation of sludge wrap shell aggregates(WSAs)instead of sand to prepare baking-free brick as the research object,the development law of mechanical properties and the influence m...Taking an industrial sludge and its preparation of sludge wrap shell aggregates(WSAs)instead of sand to prepare baking-free brick as the research object,the development law of mechanical properties and the influence mechanism of macro and micro characteristic parameters of the bricks under different sludge and WSAs replacement rates were studied through the macroscopic mechanical properties test,with the help of nuclear magnetic resonance(NMR),transmission electron microscopy-energy spectrum and other testing technology and pores and cracks analysis system(PCAS)software.The results showed that the compressive strength of each sample decreased with the increase of sludge content.When the sludge content was less than 30%,it was mainly affected by the water-binder ratio.When the sludge content was more than 30%,it was mainly affected by the sludge content.At the age of 7 days,with the increase in replacement rate of WSAs,the compressive strength of the S10 and S30 groups was higher than that of the control group.The compressive strength of the S50 experimental group was 30.38 MPa,and the loss of compressive strength was slight compared with the control group.The water absorption rate of the 28 days S100 experimental group increased by 10.71%compared with the control group.When the content of WSAs was less than 50%,the holes above 0.1μm in the brick can be reduced and transformed into smaller holes,with a decreasing trend of the plane porosity of the brick.The microscopic results of the baking-free brick showed that the three-phase system of WSAs-interface transition area-mortar was poorly bonded and delaminated compared with the gravel aggregate-interface transition area-mortar system,and damage was more likely to occur in the WSAs and interface transition area.The above results show that it is feasible to use sludge and WSAs instead of sand for the preparation of baking-free bricks.This technology not only solves the problem of sludge disposal,but also protects the over-exploitation of mineral resources,and the technology has a broad application prospect and market value.展开更多
China has abundant wind energy resources and huge development potential among developing countries.Japan is a developed country that planned to increase the use of renewable energy,especially wind energy.This research...China has abundant wind energy resources and huge development potential among developing countries.Japan is a developed country that planned to increase the use of renewable energy,especially wind energy.This research is aimed at reviewing the development of wind power and relevant policies between China and Japan.Firstly,we introduced the current status of global wind power development,such as the global installed capacity of wind power.The annual development of wind power generation in China and Japan is compared,and the distribution characteristics of wind resources are compared.Furthermore,the market share in China and Japan is introduced.Finally,according to the comparison of the government policies between China and Japan,we pointed out the existing problems in the wind power industry.In addition,we gave some suggestions on the development of wind power for China and Japan.These suggestions should be taken into account when designing national climate policies and have an important reference value for the future development of China’s wind energy industry.展开更多
With the continuous utilization of offshore wind resources,the installation depth and capacity of offshore wind turbines are increasing.In order to meet construction requirements of renewable energy,offshore wind farm...With the continuous utilization of offshore wind resources,the installation depth and capacity of offshore wind turbines are increasing.In order to meet construction requirements of renewable energy,offshore wind farms are bound to develop further and deeper into the sea.As a result,a novel kind of power generation equipment,Floating Offshore Wind Turbines(FOWT),emerges as the times require.Consequently,this paper provides an objective comment on some key scientific difficulties.Firstly,The statistics and forecast of the market demand and installed capacity of offshore wind energy show a steady growth.After that,the advantages of constructing FOWT and most floating projects in various countries are summarized.And then,the reconstruction design of blades is reviewed under“Reynolds number”and“Froude number”similarity criterion,which is a prerequisite for achieving specific aerodynamic performance.So far,this paper focuses on aerodynamic researches,including aerodynamic forces and flow fields.On this basis,pitch angle control strategies are proposed to reduce aerodynamic forces on the premise of ensuring power generations.Finally,some other joint science problems to be solved are listed.Whether theoretical analysis,numerical simulations,ocean engineering basin tests,wind tunnel experiments or prototype sea measurements,FOWT is expected to break through various obstacles and finally achieve efficient and stable commercial operations.展开更多
In recent years,the construction of offshore wind farms is developing rapidly.As the wake effect of the upstream wind turbines seriously affect the performance of the downstream wind turbines,the wake effect of offsho...In recent years,the construction of offshore wind farms is developing rapidly.As the wake effect of the upstream wind turbines seriously affect the performance of the downstream wind turbines,the wake effect of offshore wind turbines has become one of the research hotspots.First,this article reviews the research methods of wake effects,including CFD numerical simulation method,wind turbine wake model based on roughness and engineering wake models.However,there is no general model that can be used directly.Then it puts forward some factors that affect the wake of offshore wind turbines.The turbulence intensity in offshore wind fields is lower than that in onshore wind fields.This makes the wake recovery length of offshore wind turbines longer than that of onshore wind turbines.Floating offshore wind turbines are simultaneously disturbed by wind loads and wave loads.Unsteady movement of the platform caused by wave loads.It affects the development and changes of the wake of wind turbines.In this regard,the focus of research on the wake effects of offshore wind farms will be the proposal of accurate prediction models for the wake effects of sea wind farms.展开更多
The practical application of rotating triboelectric nanogenerators is often limited by the wear of high-friction surface materials and low surface charge density.In addition to the charge pump replenishment strategy,s...The practical application of rotating triboelectric nanogenerators is often limited by the wear of high-friction surface materials and low surface charge density.In addition to the charge pump replenishment strategy,suppressing charge decay is also crucial for increasing surface charge density.Here,we present a high performance rotary triboelectric nanogenerator(HPR-TENG)based on a coplanar charge pumping strategy and polyvinyl chloride(PVC)film.It has been demonstrated that applying PVC film to the surface of the storage electrode of the main TENG(M-TENG)significantly enhances the M-TENG’s output performance.Furthermore,the HPR-TENG with three layers of PVC film pasted achieved the best output performance,with a peak-topeak output voltage of 2828 V,a peak-to-peak output current of 327μA and a charge transfer of 0.81μC at 500 rpm.In addition,the output improvement effects of different materials are ranked.the TENG with 3 layers of PVC film pasted on it has a maximum output power of 748 mW at a load resistance of 4×10^(6)Ω.HPR-TENG’s output performance remains consistent after 100,000 cycles,which shows excellent stability.The excellent electrical performance of the HPR-TENG can be used as the energy supply for the tip high-voltage breakdown sensor system,which can achieve 14 breakdowns in 10 s.Due to its extraordinary electrical performance,HPRTENG can not only serve as an energy supply for cutting-edge high-voltage breakdown sensor systems,but also has the potential to serve as an energy supply for high-pressure sterilization,high-pressure vacuum and water electrolysis.展开更多
Land use and land cover(LULC)has undergone drastic changes with the rapid growth of the global population,economic development,and the expansion of agricultural activities.However,the uncertainty of classification alg...Land use and land cover(LULC)has undergone drastic changes with the rapid growth of the global population,economic development,and the expansion of agricultural activities.However,the uncertainty of classification algorithms and image resolution based on satellite data for land cover mapping,particularly cropland cover mapping,needs to be investigated sufficiently.In this study,the influence of different spatial-resolution images on classification results was explored by comparing the differences between four machine learning algorithms for LULC mapping.The classification results of this model were also compared with existing global land cover datasets to determine whether the model was capable of producing reliable results.According to the results of this study,the random forest(RF)classifier outperformed the support vector machine(SVM),decision tree(DT),and artificial neural network(ANN)with an overall accuracy(OA)and kappa coefficient of 81.99%and 0.78,respectively.However,SVM and ANN showed greater accuracy on the water class and unused land class,respectively.With increasing spatial resolution,RF’s accuracy increased initially and then decreased when classifying images with five different spatial resolutions(30 m,16 m,10 m,8 m,and 2 m).In particular,with an OA of 82.54%and a kappa coefficient of 0.78,RF performed the best on images with 8 m resolution.Additionally,the RF-based image with 8 m resolution produced a higher OA of 0.88 for cropland.Topography is the main factor that determines the classification performance of different-resolution images.The classification accuracies of RF10 m and RF30 m(10 m and 30 m resolution images,respectively,using RF)were higher(OAs of 93.59%and 94.59%,respectively)than those of the global land cover dataset(LC10 m and LC30 m,land cover images with 10 m and 30 m resolution,respectively),whose high-resolution images showed more details of the land cover.The results of this study highlight that classification algorithms and image resolution are the sources of uncertainty for land mapping.Obtaining reliable land cover mapping requires the use of appropriate classification algorithms and spatial resolution.With these results,it will be possible to develop a national land monitoring system and basic ecological climate models using LULC.展开更多
Rotary triboelectric nanogenerators have been widely used in the field of self-powering of the Internet of Things(IoT)as an effective way to capture the mechanical energy of the environment.However,the wear problem ca...Rotary triboelectric nanogenerators have been widely used in the field of self-powering of the Internet of Things(IoT)as an effective way to capture the mechanical energy of the environment.However,the wear problem caused by long-term contact of friction materials seriously affects its durability in practical applications,which makes the output performance of the system decrease.In this paper,a multi-roller rotary triboelectric nanogenerator(MR-rTENG)based on charge pump strategy is proposed.By using rolling friction,the ambient mechanical energy can be converted into electrical energy with reduced friction resistance and material wear,while the non-contact design of the main TENG can effectively enhance the durability of the system.In addition,a charge pump supplemental charging strategy is introduced to greatly improve the output performance of the MR-rTENG.At 600 rpm,the voltage,current,and charge transfer reached 1785 V,49μA,and 187 nC,respectively,with a peak power of 36.38 mW and an effective contact area of only 8 cm^(2).After 40,000 cycles,the output performance of MR-rTENG remains stable.It is able to charge a 10μF capacitor to 10 V in 15 s and light up 174 light-emitting diodes(LEDs).MR-rTENG has been demonstrated as a power source for hydrogen production from electrolyzed water,driving the production of high-purity hydrogen gas from electrolyzed water.Electrolyzing water to produce hydrogen is a green and environmentally friendly technology,but its high cost limits its large-scale application.The realization of the application of research on hydrogen production from electrolytic water driven by renewable energy has further reduced the cost and promoted the application and promotion of this green technology.展开更多
Triboelectric nanogenerator(TENG)is an innovative energy technology that converts mechanical energy into electrical energy by utilizing the triboelectric effect and the principle of static electric induction.Rotary tr...Triboelectric nanogenerator(TENG)is an innovative energy technology that converts mechanical energy into electrical energy by utilizing the triboelectric effect and the principle of static electric induction.Rotary triboelectric nanogenerator(R-TENG)can collect mechanical energy from the surrounding environment,but its shortcomings such as too large collection device and insufficient wear resistance hinder its further development.In this study,we propose a high-performance press-driven rotation triboelectric nanogenerator(HPR-TENG),which uses a gear acceleration structure to achieve efficient energy conversion by pressing,and significantly improves the output performance and durability of the device through a charge supplement strategy.At the same time,the device size is reduced to the portable range,which is more suitable for the power needs of mobile or miniaturized sensor networks.The experimental results show that the output performance can be improved by decreasing the polar distance and increasing the rotational speed.At 600 rpm,the peak-to-peak output voltage,peak-to-peak output current and charge transfer of HPR-TENG are 3128 V,221μA and 492 nC,respectively.The output remains stable after 800,000 cycles,proving its excellent stability.The output power reaches a maximum of 344 mW at a load of 3×10^(7)ΩHPR-TENG can collect kinetic and mechanical energy generated by a person to provide a stable power supply for cutting-edge high-voltage breakdown sensor systems,enabling simple and efficient inert gas or ultraviolet sensors.The proposed self-powered ultraviolet(UV)sensor,with its simple,low-cost design,has broad industrial and Internet of Things(IoT)applications,such as powering wearable health monitors,industrial condition sensors,and smart agriculture systems.展开更多
Triple-negative breast cancer(TNBC)is defined by the lack of estrogen receptor(ER),progesterone receptor,and amplified human epidermal growth factor receptor expression.TNBC accounts for~15%of all breast cancer cases ...Triple-negative breast cancer(TNBC)is defined by the lack of estrogen receptor(ER),progesterone receptor,and amplified human epidermal growth factor receptor expression.TNBC accounts for~15%of all breast cancer cases but represents>50%of breast cancer(BC)-related mortalities.展开更多
Sparse Knowledge Graph(KG)scenarios pose a challenge for previous Knowledge Graph Completion(KGC)methods,that is,the completion performance decreases rapidly with the increase of graph sparsity.This problem is also ex...Sparse Knowledge Graph(KG)scenarios pose a challenge for previous Knowledge Graph Completion(KGC)methods,that is,the completion performance decreases rapidly with the increase of graph sparsity.This problem is also exacerbated because of the widespread existence of sparse KGs in practical applications.To alleviate this challenge,we present a novel framework,LR-GCN,that is able to automatically capture valuable long-range dependency among entities to supplement insufficient structure features and distill logical reasoning knowledge for sparse KGC.The proposed approach comprises two main components:a GNN-based predictor and a reasoning path distiller.The reasoning path distiller explores high-order graph structures such as reasoning paths and encodes them as rich-semantic edges,explicitly compositing long-range dependencies into the predictor.This step also plays an essential role in densifying KGs,effectively alleviating the sparse issue.Furthermore,the path distiller further distills logical reasoning knowledge from these mined reasoning paths into the predictor.These two components are jointly optimized using a well-designed variational EM algorithm.Extensive experiments and analyses on four sparse benchmarks demonstrate the effectiveness of our proposed method.展开更多
基金supported by the National Natural Science Foundation of China(32300133 to SZ.and 32100106 to YR)the China Postdoctoral Science Foundation(2023M730965 to SZ.)+3 种基金the Science and Technology Department of Henan Province(232102311103 to SZ.)the Chinese Academy of Sciences(CAS)Youth Innovation Promotion Association(2023351 to YR)the Hubei Province Natural Science Funds(2023AFA008 and 2023AFB582 to YR)the Open project of the State Key Laboratory of Antiviral Drugs,Henan University(FX3020A030002).
文摘Human enterovirus A71(EV-A71)is a major causative agent of hand,foot and mouth disease(HFMD),which poses a significant public health threat,particularly among young children.Mitochondrial antiviral signaling protein(MAVS)and interferon regulatory factor 3(IRF3)are vital proteins for the induction of type I interferons(IFN-I)and downstream interferon-stimulated genes(ISGs)during EVA71 infection.While posttranslational modifications are known to critically influence viral infection processes,the mechanisms by which EV-A71 exploits host deubiquitinases(DUBs)for immune evasion remain poorly understood.In this study,we demonstrated that EV-A71 infection upregulated ubiquitinspecific protease 5(USP5)expression.Knockdown of USP5 not only inhibited EV-A71 replication but also observably increased the production of IFN-I and ISGs.Furthermore,USP5 also regulated the replication of EV-D68 and CVA16 and the production of IFN-I and ISGs.Mechanistically,USP5 physically interacted with MAVS and IRF3 and reduced the K63-linked polyubiquitination of MAVS and IRF3.Conversely,USP5 knockdown increased the K63-linked polyubiquitination of MAVS and IRF3,thereby accelerating the phosphorylation of IRF3 and increasing IFN-I production during EV-A71 infection.Furthermore,pharmacological inhibition of USP5 with the small-molecule inhibitor PR-619 significantly potentiated the antiviral effects of IFN against EV-A71.Collectively,our findings reveal a previously unrecognized role of USP5 in facilitating EV-A71 immune evasion by dampening MAVSand IRF3-mediated antiviral signaling.These insights provide a novel therapeutic avenue for combating EV-A71 infection through targeted modulation of the USP5-IRF3 axis.
基金Funding for this research was provided by the National Natural Science Foundation of China (42022052,42277138,and 52108337)the National Key R&D Program of China (2022YFC2803800)+1 种基金the Shandong Provincial Natural Science Foundation (ZR2020YQ29)UCL's Department of Civil,Environmental and Geomatic Engineering,and Ocean University of China.
文摘Ocean mining activities have been ongoing for nearly 70 years,making great contributions to industrialization.Given the increasing demand for energy,along with the restructuring of the energy supply catalyzed by efforts to achieve a low-carbon economy,deep seabed mining will play an important role in addressing energy-and resource-related problems in the future.However,deep seabed mining remains in the exploratory stage,with many challenges presented by the high-pressure,low-temperature,and complex geologic and hydrodynamic environments in deep-sea mining areas,which are inaccessible to human activities.Thus,considerable efforts are required to ensure sustainable,economic,reliable,and safe deep seabed mining.This study reviews the latest advances in marine engineering geology and the environment related to deep-sea min-ing activities,presents a bibliometric analysis of the development of ocean mineral resources since the 1950s,summarizes the development,theory,and issues related to techniques for the three stages of ocean mining(i.e.,exploration,extraction,and closure),and discusses the engineering geology environment,geological disasters,in-situ monitoring techniques,envi-ronmental protection requirements,and environmental effects in detail.Finally,this paper gives some key conclusions and future perspectives to provide insights for subsequent studies and commercial mining operations.
基金supported by“the Fundamental Research Funds for the Central Universities”(No.51772278)。
文摘Because of their high capacity and low potential,lithium metal anodes are considered to be promising candidates for next generation electrode materials.However,the safety concerns and limited cycling life associated with uncontrollable dendrite growth hamper practical applications.In this work,the acidified cellulose ester,which is a mixed fiber microporous membrane film,was used as a novel electrolyte additive that effectively improves the cycle stability of the lithium metal anode and inhibits dendrite growth.The focus of this paper is on inhibiting the formation and growth of lithium dendrites.The coulombic efficiency of a Li|Cu battery with this acidified cellulose ester additive remains stable at 99%after 500 cycles under a current density of 1 mA/cm^2.Symmetric batteries also remain stable after 500 cycles(1000 h)under a current density of 1 mA/cm^2.These superior properties can be ascribed to the induced nucleation and the uniform distribution of lithium ion flux.This study uncovers an approach for effectively enabling stable cycling of dendrite-free lithium metal anodes.
基金supported by the National Natural Science Foundation of China(Nos.11872090,11672019,11472035)。
文摘Highly accurate closed-form eigensolutions for flutter of three-dimensional(3D)panel with arbitrary combinations of simply supported(S),glide(G),clamped(C)and free(F)boundary conditions(BCs),such as cantilever panels,are achieved according to the linear thin plate theory and the first-order piston theory as well as the complex modal analysis,and all solutions are in a simple and explicit form.The iterative Separation-of-Variable(iSOV)method proposed by the pre-sent authors is employed to obtain the highly accurate eigensolutions.The flutter mechanism is studied with the benefit of eigenvalue properties from mathematical senses.The effects of boundary conditions,chord-thickness ratios,aerodynamic damping,aspect ratios and in-plane loads on flut-ter properties are examined.The results are compared with those of Kantorovich method and Galerkin method,and also coincide well with analytical solutions in literature,verifying the accu-racy of the present closed-form results.It is revealed that,(A)the flutter characteristics are domi-nated by the cross section properties of panels in the direction of stream flow;(B)two types of flutter,called coupled-mode flutter and zero-frequency flutter which includes zero-frequency single-mode flutter and buckling,are observed;(C)boundary conditions and in-plane loads can affect both flutter boundary and flutter type;(D)the flutter behavior of 3D panel is similar to that of the two-dimensional(2D)panel if the aspect ratio is up to a certain value;(E)four to six modes should be used in the Galerkin method for accurate eigensolutions,and the results converge to that of Kantorovich method which uses the same mode functions in the direction perpendicular to the stream flow.The present analysis method can be used as a reference for other stability issues characterized by complex eigenvalues,and the highly closed-form solutions are useful in parameter designs and can also be taken as benchmarks for the validation of numerical methods.
基金supported by the Inner Mongolia Science and Technology Program under Grant 2021GG0336by the Open Fund of Key Laboratory of Wind Energy and Solar Energy Technology(Inner Mongolia University of Technology),Ministry of Education(No.2020ZD01)in China.
文摘Due to the uncertainty of renewable energy power generation and the non-linearity of load demand,it becomes complicated to determine the capacity of each device in hybrid renewable energy power generation systems.This work aims to optimize the capacity of two types of the off-grid hybrid wind-hydrogen energy system.We considered the maximum profit of the system and the minimum loss of power supply probability as optimization goals.Firstly,we established steady-state models of the wind turbine,alkaline electrolyzer,lead-acid battery,and proton exchange membrane fuel cell in matrix laboratory software to optimize the capacity.Secondly,we analyzed the operating mode of the system and determined two system structures(system contains batteries whether or not).Finally,according to the wind speed and load in the sample area,we compared the economics of the two systems and selected the optimal configuration for the area.In the same calculation example data,the non-dominated sorting genetic algorithm-II(NSGA-II)is used to optimize the capacity of each device in the two systems.The results showed that the profit of the without battery-equipped system is 32.38%higher than another system.But the power supply reliability is the opposite.To avoid the contingency of the calculation results,we used the traditional genetic algorithm(GA)and ant colony optimization(ACO)to calculate the same example.The results showed that NSGA-II is significantly better than GA and ACO in terms of iteration steps and calculation results.The required architecture for the System-I composes of 3 numbers of 10 kW wind turbines,61 sets of 12 V·240 Ah leadacid batteries,8 kW electrolytic cell,and 6 kW PEMFC.The net profit and LPSP are ¥44,315 and 0.01254 respectively.The required architecture for the System-II composes of 2 numbers of 10 kW wind turbines,24 kW electrolytic cells,and 18 kW PEMFC.Net profit and LPSP are ¥58,663 and 0.03244,respectively.This paper provided two schemes for the optimal configuration of the hybrid wind-hydrogen energy system in islanding mode,which provided a theoretical basis for practical engineering applications.
基金supported by the National Natural Science Foundation of China(No.41976194).
文摘The spontaneous growth and evolution mechanism of metal whiskers have long been scientific problems.With the development of the integration of electronic and electrical productions,short circuits and system failures are raised by metal whiskers continuously.In the meantime,the related theories and mechanisms of whiskering problem are still vague,leading to a deficiency in the studies of environmental factors influencing the whisker phenomenon.Besides,the extreme environments such as aerospace,have been proven the accelerators to the formation of metal whiskers,resulting in a severe threaten to equipment and devices working in such environments including satellite and military equipment.To establish a comprehensive understanding to the whiskering process associated with their applicable control strategies,this study analyzes the growth phenomenon,influencing factors,formation process and evolution mechanism of metal whiskers in extreme service environments,puts forward the corresponding controlling strategies,offers a reference for the establishment of Chinese extreme aerospace strategic environment,and improves the reliability of aerospace systems.
基金supported by the Shandong Provincial Natural Science Foundation, China (Nos. 2019GSF109029, ZR2021QB190)funded by the National Natural Science Foundation of China (Nos. 21771118, 21701098, 21875128 and 22109077)+1 种基金the Taishan Scholars Climbing Program of Shandong Province (No. tspd20150201)by the Yantai Double-hundred Talents Project。
文摘With the help of the redox mediator, decoupled water-splitting allows O_(2)and H_(2)to be produced at different times, at different rates, and even in different cells, which promotes both the operation safety and the utilization of renewable power sources. However, the current densities and stabilities of these redox mediators are commonly low, which require further improvements for practical applications. Here, we propose to use supercapacitors as solid state redox mediators for decoupled water splitting. For demonstration, Na_(0.5)MnO_(2)(pseudocapacitor) and active carbon(double layer capacitor), are both used as the redox mediator. These supercapacitors show superior current density(1 A/cm^(2)) and ultralong cycle-life(8000 cycles) compared with commonly investigated battery-based mediators(NiOOH/Ni(OH)_(2)). Our research proves supercapacitors can be used as redox relay with high current density and stability, which may bring new insights in the design of decoupled water splitting systems.
基金financial support from the Guangzhou Municipal Government.
文摘Lithium metal batteries(LMBs)are considered the ideal choice for high volumetric energy density lithium-ion batteries,but uncontrolled lithium deposition poses a significant challenge to the stability of such devices.In this paper,we introduce a 2.5μm-thick asymmetric and ultrastrong separator,which can induce tissue-like lithium deposits.The asymmetric separator,denoted by utPE@Cu_(2)O,was prepared by selective synthesis of Cu_(2)O nanoparticles on one of the outer surfaces of a nanofibrous(diameter~10 nm)ultrastrong ultrahigh molecular weight polyethylene(UHMWPE)membrane.Microscopic analysis shows that the lithium deposits have tissue-like morphology,resulting in the symmetric lithium cells assembled using utPE@Cu_(2)O with symmetric Cu_(2)O coating exhibiting stable performance for over 2000 h of cycling.This work demonstrates the feasibility of a facile approach ultrathin separators for the deployment of lithium metal batteries,providing a pathway towards enhanced battery performance and safety.
基金The work was supported by the National Natural Science Foundation of China(52372174)Carbon Neutrality Research Institute Fund(CNIF20230204)Special Project of Strategic Cooperation between China National Petroleum Corporation and China University of Petroleum(Beijing)(ZLZX-2020-04).
文摘Designing high-performance and low-cost electrocatalysts for oxygen evolu-tion reaction(OER)is critical for the conversion and storage of sustainable energy technologies.Inspired by the biomineralization process,we utilized the phosphorylation sites of collagen molecules to combine with cobalt-based mononuclear precursors at the molecular level and built a three-dimensional(3D)porous hierarchical material through a bottom-up biomimetic self-assembly strategy to obtain single-atom catalysts confined on carbonized biomimetic self-assembled carriers(Co SACs/cBSC)after subsequent high-temperature annealing.In this strategy,the biomolecule improved the anchoring efficiency of the metal precursor through precise functional groups;meanwhile,the binding-then-assembling strategy also effectively suppressed the nonspecific adsorption of metal ions,ultimately preventing atomic agglomeration and achieving strong electronic metal-support interactions(EMSIs).Experimental characterizations confirm that binding forms between cobalt metal and carbonized self-assembled substrate(Co–O_(4)–P).Theoretical calculations disclose that the local environment changes significantly tailored the Co d-band center,and optimized the binding energy of oxygenated intermediates and the energy barrier of oxygen release.As a result,the obtained Co SACs/cBSC catalyst can achieve remarkable OER activity and 24 h durability in 1 M KOH(η_(10) at 288 mV;Tafel slope of 44 mV dec^(-1)),better than other transition metal-based catalysts and commercial IrO_(2).Overall,we presented a self-assembly strategy to prepare transition metal SACs with strong EMSIs,providing a new avenue for the preparation of efficient catalysts with fine atomic structures.
基金the Natural Science Foundation of Henan Province(202300410270)Graduate Education Innovation Program fund of North China University of Water Resources and Electric Power(YK-2021-49).
文摘Taking an industrial sludge and its preparation of sludge wrap shell aggregates(WSAs)instead of sand to prepare baking-free brick as the research object,the development law of mechanical properties and the influence mechanism of macro and micro characteristic parameters of the bricks under different sludge and WSAs replacement rates were studied through the macroscopic mechanical properties test,with the help of nuclear magnetic resonance(NMR),transmission electron microscopy-energy spectrum and other testing technology and pores and cracks analysis system(PCAS)software.The results showed that the compressive strength of each sample decreased with the increase of sludge content.When the sludge content was less than 30%,it was mainly affected by the water-binder ratio.When the sludge content was more than 30%,it was mainly affected by the sludge content.At the age of 7 days,with the increase in replacement rate of WSAs,the compressive strength of the S10 and S30 groups was higher than that of the control group.The compressive strength of the S50 experimental group was 30.38 MPa,and the loss of compressive strength was slight compared with the control group.The water absorption rate of the 28 days S100 experimental group increased by 10.71%compared with the control group.When the content of WSAs was less than 50%,the holes above 0.1μm in the brick can be reduced and transformed into smaller holes,with a decreasing trend of the plane porosity of the brick.The microscopic results of the baking-free brick showed that the three-phase system of WSAs-interface transition area-mortar was poorly bonded and delaminated compared with the gravel aggregate-interface transition area-mortar system,and damage was more likely to occur in the WSAs and interface transition area.The above results show that it is feasible to use sludge and WSAs instead of sand for the preparation of baking-free bricks.This technology not only solves the problem of sludge disposal,but also protects the over-exploitation of mineral resources,and the technology has a broad application prospect and market value.
文摘China has abundant wind energy resources and huge development potential among developing countries.Japan is a developed country that planned to increase the use of renewable energy,especially wind energy.This research is aimed at reviewing the development of wind power and relevant policies between China and Japan.Firstly,we introduced the current status of global wind power development,such as the global installed capacity of wind power.The annual development of wind power generation in China and Japan is compared,and the distribution characteristics of wind resources are compared.Furthermore,the market share in China and Japan is introduced.Finally,according to the comparison of the government policies between China and Japan,we pointed out the existing problems in the wind power industry.In addition,we gave some suggestions on the development of wind power for China and Japan.These suggestions should be taken into account when designing national climate policies and have an important reference value for the future development of China’s wind energy industry.
文摘With the continuous utilization of offshore wind resources,the installation depth and capacity of offshore wind turbines are increasing.In order to meet construction requirements of renewable energy,offshore wind farms are bound to develop further and deeper into the sea.As a result,a novel kind of power generation equipment,Floating Offshore Wind Turbines(FOWT),emerges as the times require.Consequently,this paper provides an objective comment on some key scientific difficulties.Firstly,The statistics and forecast of the market demand and installed capacity of offshore wind energy show a steady growth.After that,the advantages of constructing FOWT and most floating projects in various countries are summarized.And then,the reconstruction design of blades is reviewed under“Reynolds number”and“Froude number”similarity criterion,which is a prerequisite for achieving specific aerodynamic performance.So far,this paper focuses on aerodynamic researches,including aerodynamic forces and flow fields.On this basis,pitch angle control strategies are proposed to reduce aerodynamic forces on the premise of ensuring power generations.Finally,some other joint science problems to be solved are listed.Whether theoretical analysis,numerical simulations,ocean engineering basin tests,wind tunnel experiments or prototype sea measurements,FOWT is expected to break through various obstacles and finally achieve efficient and stable commercial operations.
基金The work was sponsored by the Open Fund of Key Laboratory of Wind Energy and Solar Energy Technology(Inner Mongolia University of Technology),Ministry of Education(No.2020ZD01)in Chinathe Fund of Southern Marine Science and Engineering Guangdong Laboratory(Zhanjiang)(ZJW-2019-02).
文摘In recent years,the construction of offshore wind farms is developing rapidly.As the wake effect of the upstream wind turbines seriously affect the performance of the downstream wind turbines,the wake effect of offshore wind turbines has become one of the research hotspots.First,this article reviews the research methods of wake effects,including CFD numerical simulation method,wind turbine wake model based on roughness and engineering wake models.However,there is no general model that can be used directly.Then it puts forward some factors that affect the wake of offshore wind turbines.The turbulence intensity in offshore wind fields is lower than that in onshore wind fields.This makes the wake recovery length of offshore wind turbines longer than that of onshore wind turbines.Floating offshore wind turbines are simultaneously disturbed by wind loads and wave loads.Unsteady movement of the platform caused by wave loads.It affects the development and changes of the wake of wind turbines.In this regard,the focus of research on the wake effects of offshore wind farms will be the proposal of accurate prediction models for the wake effects of sea wind farms.
基金support from the Natural Science Foundation for Young Scientists of Shanxi Province(No.202203021212127)the Innovative Research Group Project of National Natural Science Foundation of China(No.51821003).
文摘The practical application of rotating triboelectric nanogenerators is often limited by the wear of high-friction surface materials and low surface charge density.In addition to the charge pump replenishment strategy,suppressing charge decay is also crucial for increasing surface charge density.Here,we present a high performance rotary triboelectric nanogenerator(HPR-TENG)based on a coplanar charge pumping strategy and polyvinyl chloride(PVC)film.It has been demonstrated that applying PVC film to the surface of the storage electrode of the main TENG(M-TENG)significantly enhances the M-TENG’s output performance.Furthermore,the HPR-TENG with three layers of PVC film pasted achieved the best output performance,with a peak-topeak output voltage of 2828 V,a peak-to-peak output current of 327μA and a charge transfer of 0.81μC at 500 rpm.In addition,the output improvement effects of different materials are ranked.the TENG with 3 layers of PVC film pasted on it has a maximum output power of 748 mW at a load resistance of 4×10^(6)Ω.HPR-TENG’s output performance remains consistent after 100,000 cycles,which shows excellent stability.The excellent electrical performance of the HPR-TENG can be used as the energy supply for the tip high-voltage breakdown sensor system,which can achieve 14 breakdowns in 10 s.Due to its extraordinary electrical performance,HPRTENG can not only serve as an energy supply for cutting-edge high-voltage breakdown sensor systems,but also has the potential to serve as an energy supply for high-pressure sterilization,high-pressure vacuum and water electrolysis.
基金supported by the Natural Science Research General Program of Shanxi Province Basic Research Project(Grant No.202203021221231).
文摘Land use and land cover(LULC)has undergone drastic changes with the rapid growth of the global population,economic development,and the expansion of agricultural activities.However,the uncertainty of classification algorithms and image resolution based on satellite data for land cover mapping,particularly cropland cover mapping,needs to be investigated sufficiently.In this study,the influence of different spatial-resolution images on classification results was explored by comparing the differences between four machine learning algorithms for LULC mapping.The classification results of this model were also compared with existing global land cover datasets to determine whether the model was capable of producing reliable results.According to the results of this study,the random forest(RF)classifier outperformed the support vector machine(SVM),decision tree(DT),and artificial neural network(ANN)with an overall accuracy(OA)and kappa coefficient of 81.99%and 0.78,respectively.However,SVM and ANN showed greater accuracy on the water class and unused land class,respectively.With increasing spatial resolution,RF’s accuracy increased initially and then decreased when classifying images with five different spatial resolutions(30 m,16 m,10 m,8 m,and 2 m).In particular,with an OA of 82.54%and a kappa coefficient of 0.78,RF performed the best on images with 8 m resolution.Additionally,the RF-based image with 8 m resolution produced a higher OA of 0.88 for cropland.Topography is the main factor that determines the classification performance of different-resolution images.The classification accuracies of RF10 m and RF30 m(10 m and 30 m resolution images,respectively,using RF)were higher(OAs of 93.59%and 94.59%,respectively)than those of the global land cover dataset(LC10 m and LC30 m,land cover images with 10 m and 30 m resolution,respectively),whose high-resolution images showed more details of the land cover.The results of this study highlight that classification algorithms and image resolution are the sources of uncertainty for land mapping.Obtaining reliable land cover mapping requires the use of appropriate classification algorithms and spatial resolution.With these results,it will be possible to develop a national land monitoring system and basic ecological climate models using LULC.
基金support from the National Natural Science Foundation of China(No.62401519)the Natural Science Foundation for Young Scientists of Shanxi Province(No.202203021212127)Key Research and Development Program of Shanxi Province(No.202102100401014).
文摘Rotary triboelectric nanogenerators have been widely used in the field of self-powering of the Internet of Things(IoT)as an effective way to capture the mechanical energy of the environment.However,the wear problem caused by long-term contact of friction materials seriously affects its durability in practical applications,which makes the output performance of the system decrease.In this paper,a multi-roller rotary triboelectric nanogenerator(MR-rTENG)based on charge pump strategy is proposed.By using rolling friction,the ambient mechanical energy can be converted into electrical energy with reduced friction resistance and material wear,while the non-contact design of the main TENG can effectively enhance the durability of the system.In addition,a charge pump supplemental charging strategy is introduced to greatly improve the output performance of the MR-rTENG.At 600 rpm,the voltage,current,and charge transfer reached 1785 V,49μA,and 187 nC,respectively,with a peak power of 36.38 mW and an effective contact area of only 8 cm^(2).After 40,000 cycles,the output performance of MR-rTENG remains stable.It is able to charge a 10μF capacitor to 10 V in 15 s and light up 174 light-emitting diodes(LEDs).MR-rTENG has been demonstrated as a power source for hydrogen production from electrolyzed water,driving the production of high-purity hydrogen gas from electrolyzed water.Electrolyzing water to produce hydrogen is a green and environmentally friendly technology,but its high cost limits its large-scale application.The realization of the application of research on hydrogen production from electrolytic water driven by renewable energy has further reduced the cost and promoted the application and promotion of this green technology.
基金the National Natural Science Foundation of China(No.62405294).
文摘Triboelectric nanogenerator(TENG)is an innovative energy technology that converts mechanical energy into electrical energy by utilizing the triboelectric effect and the principle of static electric induction.Rotary triboelectric nanogenerator(R-TENG)can collect mechanical energy from the surrounding environment,but its shortcomings such as too large collection device and insufficient wear resistance hinder its further development.In this study,we propose a high-performance press-driven rotation triboelectric nanogenerator(HPR-TENG),which uses a gear acceleration structure to achieve efficient energy conversion by pressing,and significantly improves the output performance and durability of the device through a charge supplement strategy.At the same time,the device size is reduced to the portable range,which is more suitable for the power needs of mobile or miniaturized sensor networks.The experimental results show that the output performance can be improved by decreasing the polar distance and increasing the rotational speed.At 600 rpm,the peak-to-peak output voltage,peak-to-peak output current and charge transfer of HPR-TENG are 3128 V,221μA and 492 nC,respectively.The output remains stable after 800,000 cycles,proving its excellent stability.The output power reaches a maximum of 344 mW at a load of 3×10^(7)ΩHPR-TENG can collect kinetic and mechanical energy generated by a person to provide a stable power supply for cutting-edge high-voltage breakdown sensor systems,enabling simple and efficient inert gas or ultraviolet sensors.The proposed self-powered ultraviolet(UV)sensor,with its simple,low-cost design,has broad industrial and Internet of Things(IoT)applications,such as powering wearable health monitors,industrial condition sensors,and smart agriculture systems.
基金supported by grants from the National Key R&D Program of China (No.2022YFC2703701 to Qiji Liu)the National Natural Science Foundation of China (No.82271901,32070586)+2 种基金the Shandong Provincial Natural Science Foundation,China (No.ZR2020MH086)Taishan Scholar Program of Shandong Province (tsqn202211318)NHC Key Laboratory of Birth Defects Prevention,China (No.ZD202101).
文摘Triple-negative breast cancer(TNBC)is defined by the lack of estrogen receptor(ER),progesterone receptor,and amplified human epidermal growth factor receptor expression.TNBC accounts for~15%of all breast cancer cases but represents>50%of breast cancer(BC)-related mortalities.
基金supported by the National Key R&D Program of China(2022YFF0903301)the National Natural Science Foundation of China(Grant Nos.U22B2059,61976073,62276083)+1 种基金the Shenzhen Foundational Research Funding(JCYJ20200109113441941)the Major Key Project of PCL(PCL2021A06).
文摘Sparse Knowledge Graph(KG)scenarios pose a challenge for previous Knowledge Graph Completion(KGC)methods,that is,the completion performance decreases rapidly with the increase of graph sparsity.This problem is also exacerbated because of the widespread existence of sparse KGs in practical applications.To alleviate this challenge,we present a novel framework,LR-GCN,that is able to automatically capture valuable long-range dependency among entities to supplement insufficient structure features and distill logical reasoning knowledge for sparse KGC.The proposed approach comprises two main components:a GNN-based predictor and a reasoning path distiller.The reasoning path distiller explores high-order graph structures such as reasoning paths and encodes them as rich-semantic edges,explicitly compositing long-range dependencies into the predictor.This step also plays an essential role in densifying KGs,effectively alleviating the sparse issue.Furthermore,the path distiller further distills logical reasoning knowledge from these mined reasoning paths into the predictor.These two components are jointly optimized using a well-designed variational EM algorithm.Extensive experiments and analyses on four sparse benchmarks demonstrate the effectiveness of our proposed method.
