The antioxidant ability of capsules containing oats avenanthramides on human body was evaluated in present study.Healthy people were randomized to supplementation with oats-derived avenanthramides capsules or placebo ...The antioxidant ability of capsules containing oats avenanthramides on human body was evaluated in present study.Healthy people were randomized to supplementation with oats-derived avenanthramides capsules or placebo for 1 mon.Plasma lipid peroxides and antioxidant status were measured.For 8 capsules （containing 3.12 mg avenanthramides） groups,the levels of serum superoxide dismutase （SOD） and reduced glutathione hormone （GSH） were significantly increased by 8.4 and 17.9%,respectively （P0.05）,and malondialdehyde （MDA） level significantly decreased by 28.1%.The total cholesterol （TC）,triglyceride （TG）,and low density lipoprotein cholesterol （LDL-C） levels were lowered by 11.1,28.1,and 15.1%,respectively （P0.05）.The high density blood lipoprotein cholesterol （HDL-C） levels in the same treat was increased by 13.2%.Based on our research,it can be concluded that oats extract containing avenanthramides possessed a high antioxidative activity on humans.It indicated that oat avenanthramides could be used to prevent hyperlipemic and angiocardiopathy.展开更多
Ginsenosides Rg 1,Rb 1,R 1,Rd,and Re are major constituents of Panax notoginseng,a famous traditional Chinese medicinal herb,which has both stimulative and inhibitory effects on the central nervous system (CNS).The mo...Ginsenosides Rg 1,Rb 1,R 1,Rd,and Re are major constituents of Panax notoginseng,a famous traditional Chinese medicinal herb,which has both stimulative and inhibitory effects on the central nervous system (CNS).The monoamine hypothesis proposes that depression is a result of the depletion of 5-hydroxytryptamine (5-HT),norepinephrine (NE) and dopamine (DA) in addition to the activation of monoamine oxidase in the CNS.The purpose of this study was to determine whether P.notoginseng Saponin (PNS) has an antidepressant activity.We investigated the antidepressant-like activities of Rg 1,Rb 1,R 1,Rd,and Re in mice,using two animal models of depression.In addition,we analyzed the neurochemicals by the chronic unpredictable mild stress test.Our results showed that Rb 1,Rd,and Re treatment at 10 mg kg-1 significantly reduced the duration of immobility in both the tail suspension and forced swimming tests.Rb 1,Rd,and Re increases in 5HT and NE levels at 10 mg kg-1 in both the frontal cortex and hippocampus.Dopamine levels increased in the hippocampus and the striatum.Moreover,5-hydroxyindoleacetic acid (5-HIAA) levels were found increased in the hippocampus.These findings suggest that the antidepressant effects of Rb 1,Rd,and Re may be related to the increase in 5-HT and NE in the CNS,and through the alterations in the synthesis or metabolism of dopamine.展开更多
We study the energy level statistics of the SO(5) limit of super-symmetry U(6/4) in odd-A nucleus using the interacting boson-fermion model. The nearest neighbor spacing distribution (NSD) and the spectral rigidity (...We study the energy level statistics of the SO(5) limit of super-symmetry U(6/4) in odd-A nucleus using the interacting boson-fermion model. The nearest neighbor spacing distribution (NSD) and the spectral rigidity (△3)are investigated, and the factors that affect the properties of level statistics are also discussed. The results show that the boson number N is a dominant factor. If N is small, both the interaction strengths of subgroups SOB(5) and SOBF(5)and the spin play important roles in the energy level statistics, however, along with the increase of N, the statistics distribution would tend to be in Poisson form.展开更多
The ground bands and β-bands of four nuclei 230,232Th and 232,234U in the actinide region are investigated by introducing a collective Do pair into the projected shell model.We discuss the collectivity of the Do pair...The ground bands and β-bands of four nuclei 230,232Th and 232,234U in the actinide region are investigated by introducing a collective Do pair into the projected shell model.We discuss the collectivity of the Do pair.The calculated energy schemes agree well with experimental data,and so do the E2 transition rates.展开更多
The rare-earth nuclei^(174)Hf and^(174)are studied in the framework of the projected shell model.The calculations are carried out with an improved version of code which contains all types of four-quasiparticle basis i...The rare-earth nuclei^(174)Hf and^(174)are studied in the framework of the projected shell model.The calculations are carried out with an improved version of code which contains all types of four-quasiparticle basis in the configuration space.Both the yrast band and the multi-quasiparticle excited bands can be well reproduced.Compared with the experimental data,our calculations improve the previous resulst,especially for high spin states.This improvement suggests that the newly added configurations are important.In^(174)Yb,a new possible configuration is suggested for the observed K^(л)=14^(+)band,and the decay of the K^(л)=6^(+)isomeric state to the yrast band is discussed.展开更多
Background Human papillomavirus （HPV） is believed to be the most common sexually transmitted infection. However,little is known about the prevalence and distribution of HPV types in China. We aimed to assess the pre...Background Human papillomavirus （HPV） is believed to be the most common sexually transmitted infection. However,little is known about the prevalence and distribution of HPV types in China. We aimed to assess the prevalence and the distribution of HPV types as well as risks for abnormal cervical cytology in women who reside in the Tibetan Autonomous Region of China.Methods A cross-sectional study was performed involving a sample of 3036 women. An epidemiological questionnaire was applied and cervical specimens were obtained for liquid-based cytology and HPV DNA detection. Statistical analysis included chi-square and Logistic regression model.Results In this population, 3.66% （111/3036） had atypical squamous cells of undetermined significance （ASCUS）,1.45% （44/3036） low-grade squamous intraepithelial lesions （LSIL） and 1.09% （33/3036） had high-grade squamous intraepithelial lesions （HSIL）. Tibetan women （5.74%, 137/2387） exhibited lower abnormal cytology rates than non-Tibetan women （8.01%, 52/649, P=0.03）. The overall prevalence of HPV infection was 9.19% （279/3036）. We failed to identify any differences in HPV prevalence by age. In the groups with normal, ASCUS, LSIL and HSIL, the overall HPV prevalences were 7.41% （211/2847）, 24.32% （27/111）, 56.82% （25/44） and 45.45% （15/33）, respectively. HPV 16 （1.52%,46/3036） was the most common type, and was also the most prevalent in women with ASCUS （8.11%, 9/111） and HSIL （15.15%, 5/33）. The most common HPV type for Tibetan women was HPV 16 （1.42%, 34/2387）, whereas for non-Tibetan individuals it was HPV 33 （2.31%, 15/649）. Of the 279 HPV-infected women, 40 individuals （14.34%） presented with multiple HPV positivity. Women who had two pregnancies were more likely to have abnormal cytology smear （OR=1.67;95% CI： 1.07-2.61）.Conclusions A low prevalence of HPV positivity was observed in women who reside in the Tibetan Autonomous Region of China. The prevalence of abnormal cervical cytology and HPV type distributions were different between Tibetan and non-Tibetan women.展开更多
Cervical cancer is the second most common cancer in women worldwide. There is a strong and consistentassociation of genital HPV infection with cervical cancer and its precancerous lesions.1 This study was undertaken t...Cervical cancer is the second most common cancer in women worldwide. There is a strong and consistentassociation of genital HPV infection with cervical cancer and its precancerous lesions.1 This study was undertaken to describe the prevalence of cytological abnormality in relation to HPV infection in general female population of Qujing city, Yunnan province, southwest China.展开更多
基金supported by the Talent Fund of Chinese Academy of Agricultural Sciences,Chinathe Technology Transformation Fund,the Ministry of Sciences and Technology,China
文摘The antioxidant ability of capsules containing oats avenanthramides on human body was evaluated in present study.Healthy people were randomized to supplementation with oats-derived avenanthramides capsules or placebo for 1 mon.Plasma lipid peroxides and antioxidant status were measured.For 8 capsules （containing 3.12 mg avenanthramides） groups,the levels of serum superoxide dismutase （SOD） and reduced glutathione hormone （GSH） were significantly increased by 8.4 and 17.9%,respectively （P0.05）,and malondialdehyde （MDA） level significantly decreased by 28.1%.The total cholesterol （TC）,triglyceride （TG）,and low density lipoprotein cholesterol （LDL-C） levels were lowered by 11.1,28.1,and 15.1%,respectively （P0.05）.The high density blood lipoprotein cholesterol （HDL-C） levels in the same treat was increased by 13.2%.Based on our research,it can be concluded that oats extract containing avenanthramides possessed a high antioxidative activity on humans.It indicated that oat avenanthramides could be used to prevent hyperlipemic and angiocardiopathy.
基金supported by the Talent Fund to Dr.Ren Guixing,Chinese Academy of Agricultural Sciences,China
文摘Ginsenosides Rg 1,Rb 1,R 1,Rd,and Re are major constituents of Panax notoginseng,a famous traditional Chinese medicinal herb,which has both stimulative and inhibitory effects on the central nervous system (CNS).The monoamine hypothesis proposes that depression is a result of the depletion of 5-hydroxytryptamine (5-HT),norepinephrine (NE) and dopamine (DA) in addition to the activation of monoamine oxidase in the CNS.The purpose of this study was to determine whether P.notoginseng Saponin (PNS) has an antidepressant activity.We investigated the antidepressant-like activities of Rg 1,Rb 1,R 1,Rd,and Re in mice,using two animal models of depression.In addition,we analyzed the neurochemicals by the chronic unpredictable mild stress test.Our results showed that Rb 1,Rd,and Re treatment at 10 mg kg-1 significantly reduced the duration of immobility in both the tail suspension and forced swimming tests.Rb 1,Rd,and Re increases in 5HT and NE levels at 10 mg kg-1 in both the frontal cortex and hippocampus.Dopamine levels increased in the hippocampus and the striatum.Moreover,5-hydroxyindoleacetic acid (5-HIAA) levels were found increased in the hippocampus.These findings suggest that the antidepressant effects of Rb 1,Rd,and Re may be related to the increase in 5-HT and NE in the CNS,and through the alterations in the synthesis or metabolism of dopamine.
文摘We study the energy level statistics of the SO(5) limit of super-symmetry U(6/4) in odd-A nucleus using the interacting boson-fermion model. The nearest neighbor spacing distribution (NSD) and the spectral rigidity (△3)are investigated, and the factors that affect the properties of level statistics are also discussed. The results show that the boson number N is a dominant factor. If N is small, both the interaction strengths of subgroups SOB(5) and SOBF(5)and the spin play important roles in the energy level statistics, however, along with the increase of N, the statistics distribution would tend to be in Poisson form.
基金Supported by National Natural Science Foundation of China(No 10975116),the Program for New Century Excellent Talents in University(No NCET-07-0730)the Fundamental Research Funds for the Central Universities under Contract No 2010121011.
文摘The ground bands and β-bands of four nuclei 230,232Th and 232,234U in the actinide region are investigated by introducing a collective Do pair into the projected shell model.We discuss the collectivity of the Do pair.The calculated energy schemes agree well with experimental data,and so do the E2 transition rates.
基金Supported by the National Natural Science Foundation of China under Grant Nos 10605018 and 10975116,the Program for New Century Excellent Talents in University(No NCET-07-0730)the Fundamental Research Funds for the Central Universities(No 2010121011).
文摘The rare-earth nuclei^(174)Hf and^(174)are studied in the framework of the projected shell model.The calculations are carried out with an improved version of code which contains all types of four-quasiparticle basis in the configuration space.Both the yrast band and the multi-quasiparticle excited bands can be well reproduced.Compared with the experimental data,our calculations improve the previous resulst,especially for high spin states.This improvement suggests that the newly added configurations are important.In^(174)Yb,a new possible configuration is suggested for the observed K^(л)=14^(+)band,and the decay of the K^(л)=6^(+)isomeric state to the yrast band is discussed.
文摘Background Human papillomavirus （HPV） is believed to be the most common sexually transmitted infection. However,little is known about the prevalence and distribution of HPV types in China. We aimed to assess the prevalence and the distribution of HPV types as well as risks for abnormal cervical cytology in women who reside in the Tibetan Autonomous Region of China.Methods A cross-sectional study was performed involving a sample of 3036 women. An epidemiological questionnaire was applied and cervical specimens were obtained for liquid-based cytology and HPV DNA detection. Statistical analysis included chi-square and Logistic regression model.Results In this population, 3.66% （111/3036） had atypical squamous cells of undetermined significance （ASCUS）,1.45% （44/3036） low-grade squamous intraepithelial lesions （LSIL） and 1.09% （33/3036） had high-grade squamous intraepithelial lesions （HSIL）. Tibetan women （5.74%, 137/2387） exhibited lower abnormal cytology rates than non-Tibetan women （8.01%, 52/649, P=0.03）. The overall prevalence of HPV infection was 9.19% （279/3036）. We failed to identify any differences in HPV prevalence by age. In the groups with normal, ASCUS, LSIL and HSIL, the overall HPV prevalences were 7.41% （211/2847）, 24.32% （27/111）, 56.82% （25/44） and 45.45% （15/33）, respectively. HPV 16 （1.52%,46/3036） was the most common type, and was also the most prevalent in women with ASCUS （8.11%, 9/111） and HSIL （15.15%, 5/33）. The most common HPV type for Tibetan women was HPV 16 （1.42%, 34/2387）, whereas for non-Tibetan individuals it was HPV 33 （2.31%, 15/649）. Of the 279 HPV-infected women, 40 individuals （14.34%） presented with multiple HPV positivity. Women who had two pregnancies were more likely to have abnormal cytology smear （OR=1.67;95% CI： 1.07-2.61）.Conclusions A low prevalence of HPV positivity was observed in women who reside in the Tibetan Autonomous Region of China. The prevalence of abnormal cervical cytology and HPV type distributions were different between Tibetan and non-Tibetan women.
文摘Cervical cancer is the second most common cancer in women worldwide. There is a strong and consistentassociation of genital HPV infection with cervical cancer and its precancerous lesions.1 This study was undertaken to describe the prevalence of cytological abnormality in relation to HPV infection in general female population of Qujing city, Yunnan province, southwest China.
