目的分析滋阴颗粒剂方治疗女童特发性性早熟的临床疗效,观察其对患儿的临床症状、体征、辅助检查及生长发育的影响。方法选取2021年1月至2022年1月就诊于绍兴市妇幼保健院小儿内分泌科的特发性性早熟女童90例,采用随机数字表法分为大补...目的分析滋阴颗粒剂方治疗女童特发性性早熟的临床疗效,观察其对患儿的临床症状、体征、辅助检查及生长发育的影响。方法选取2021年1月至2022年1月就诊于绍兴市妇幼保健院小儿内分泌科的特发性性早熟女童90例,采用随机数字表法分为大补阴丸组(阳性对照组)和滋阴颗粒组(治疗组),每组各45例。滋阴颗粒组给予滋阴颗粒剂方治疗,大补阴丸组给予大补阴丸治疗。比较两组女童治疗前(0个月)、治疗后(3个月、6个月)的临床症状、体征、卵泡刺激素(follicle stimulating hormone,FSH)、促黄体生成素(luteinizing hormone,LH)、雌二醇(estradiol,E_(2))和泌乳素(prolactin,PRL)水平、子宫卵巢容积、中医症候评分(traditional Chinese medicine symtom score,TCMSS)变化,评估滋阴颗粒剂方及大补阴丸的疗效。结果治疗前,两组女童的年龄、体质量、身高、Tanner分期、血清基础性激素值、骨龄等比较,差异均无统计学意义(P>0.05),治疗6个月后,两组的乳核指数比治疗前有所减少,差异有统计学意义(P<0.01);两组的子宫容积与治疗前比较均减小,差异均有统计学意义(P<0.05);两组的FSH、LH、E2值、卵巢容积与治疗前比较均降低,差异均有统计学意义(P<0.01)。结论滋阴颗粒剂方能有效改善女童特发性性早熟的临床症状,降低FSH、LH、E2值,缩小子宫容积、卵巢容积并且操作方便,依从性强,具有临床应用价值。展开更多
Research and development of high-temperature superconducting(HTS)apparatus are ongoing in the world with the great progress on the HTS tapes in recent years.The most attractive applications require the HTS tapes to pe...Research and development of high-temperature superconducting(HTS)apparatus are ongoing in the world with the great progress on the HTS tapes in recent years.The most attractive applications require the HTS tapes to perform well upon the application of an alternative current(AC)and/or an AC magnetic field.The electromagnetic properties of the HTS tapes including anisotropy,uniformity,alternative current(AC losses)and stability as well as mechanical characteristics are important fundamental parameters for these applications.This paper summarizes and focuses on several typical measurement principles and methods as well as apparatuses of those characteristic parameters except for their stability developed in past several years in China.展开更多
文摘目的分析滋阴颗粒剂方治疗女童特发性性早熟的临床疗效,观察其对患儿的临床症状、体征、辅助检查及生长发育的影响。方法选取2021年1月至2022年1月就诊于绍兴市妇幼保健院小儿内分泌科的特发性性早熟女童90例,采用随机数字表法分为大补阴丸组(阳性对照组)和滋阴颗粒组(治疗组),每组各45例。滋阴颗粒组给予滋阴颗粒剂方治疗,大补阴丸组给予大补阴丸治疗。比较两组女童治疗前(0个月)、治疗后(3个月、6个月)的临床症状、体征、卵泡刺激素(follicle stimulating hormone,FSH)、促黄体生成素(luteinizing hormone,LH)、雌二醇(estradiol,E_(2))和泌乳素(prolactin,PRL)水平、子宫卵巢容积、中医症候评分(traditional Chinese medicine symtom score,TCMSS)变化,评估滋阴颗粒剂方及大补阴丸的疗效。结果治疗前,两组女童的年龄、体质量、身高、Tanner分期、血清基础性激素值、骨龄等比较,差异均无统计学意义(P>0.05),治疗6个月后,两组的乳核指数比治疗前有所减少,差异有统计学意义(P<0.01);两组的子宫容积与治疗前比较均减小,差异均有统计学意义(P<0.05);两组的FSH、LH、E2值、卵巢容积与治疗前比较均降低,差异均有统计学意义(P<0.01)。结论滋阴颗粒剂方能有效改善女童特发性性早熟的临床症状,降低FSH、LH、E2值,缩小子宫容积、卵巢容积并且操作方便,依从性强,具有临床应用价值。
基金supported by Beijing Education Commissions(Grant No.GJ2013009)the National Natural Science Foundation of China(Grant No.51077051)
文摘Research and development of high-temperature superconducting(HTS)apparatus are ongoing in the world with the great progress on the HTS tapes in recent years.The most attractive applications require the HTS tapes to perform well upon the application of an alternative current(AC)and/or an AC magnetic field.The electromagnetic properties of the HTS tapes including anisotropy,uniformity,alternative current(AC losses)and stability as well as mechanical characteristics are important fundamental parameters for these applications.This paper summarizes and focuses on several typical measurement principles and methods as well as apparatuses of those characteristic parameters except for their stability developed in past several years in China.
