以中国知网(CNKI)和Web of Science(WOS)检索和遴选所得的中文和外文相关核心文献为基础数据,借助CiteSpace进行文献可视化及对比分析。研究发现近年来老年视角下建成环境可步行性相关研究热度持续提升,维度和深度有一定发展,国外研究...以中国知网(CNKI)和Web of Science(WOS)检索和遴选所得的中文和外文相关核心文献为基础数据,借助CiteSpace进行文献可视化及对比分析。研究发现近年来老年视角下建成环境可步行性相关研究热度持续提升,维度和深度有一定发展,国外研究较国内起步早,国内研究缺少学科交叉融合,创新性较弱,在地理科学及交通运输领域具有拓展价值。展开更多
Zinc oxide nanoparticles were synthesized using bovine serum albumin as stabilizers through a facile one-pot strategy in aqueous media. The morphology and crystal phase of the zinc oxide nanoparticles were determined ...Zinc oxide nanoparticles were synthesized using bovine serum albumin as stabilizers through a facile one-pot strategy in aqueous media. The morphology and crystal phase of the zinc oxide nanoparticles were determined by transmission electron microscopy, X-ray diffractograms, and Fourier transform infrared spectroscopy. The synthesized ZnO nanoparticles exhibited strong absorption and photoluminescence properties in the visible wavelength region based on the fluorescence and UV-visible spectroscopy. Based on the results, the zinc oxide nanoparticles could effectively degrade the organic dyes through the mediation of the hydroxyl radical under visible light irradiation. Furthermore, the zinc oxide nanoparticles show good recycling stability during the photocatalytic experiments. These results suggested that the as-prepared zinc oxide nanoparticles might be used as a potential photocatalyst to efficiently treat the organic pollutants.展开更多
Colloidal semiconductor nanoparticles (quantum dots, QDs) have attracted a lot of interests in numerous biological and medical applications due to their potent fluorescent properties. However, the possible toxic effec...Colloidal semiconductor nanoparticles (quantum dots, QDs) have attracted a lot of interests in numerous biological and medical applications due to their potent fluorescent properties. However, the possible toxic effects of quantum dots remain an issue of debate. In this study, we aimed to evaluate the cytocompatibility of bovine serum albumin (BSA) conjugated zinc oxide QDs for C2C12 cells. In the experiment, ZnO QDs were synthesized by using BSA as the structure directing agent, and the morphology and crystal phase of ZnO QDs were determined by transmission electron microscopy, X-ray diffractograms and Fourier transform infrared spectrograph techniques. The inverted fluorescence microscope results showed that ZnO QDs were distributed inside the cells. The toxicity of ZnO QDs was assessed by MTT methods, which revealed that ZnO QDs were highly cytocompatible in the concentration less than 200 μM. However, when the concentration of QDs was higher than 1 000 μM ZnO QDs showed significantly toxicity, which was ascribed to generation of free zinc and formation of reactive oxygen species (ROS). Furthermore, the morphological observations exhibited that cells treated with ZnO QDs showed altered morphology, depolymerized cytoskeleton and irregular-shaped nuclei. This study provides helpful guidances on the future safe use and manipulation of QDs to make them suitable tools in nanomedicine.展开更多
文摘以中国知网(CNKI)和Web of Science(WOS)检索和遴选所得的中文和外文相关核心文献为基础数据,借助CiteSpace进行文献可视化及对比分析。研究发现近年来老年视角下建成环境可步行性相关研究热度持续提升,维度和深度有一定发展,国外研究较国内起步早,国内研究缺少学科交叉融合,创新性较弱,在地理科学及交通运输领域具有拓展价值。
基金Funded by the Science&Technology Foundation of Dongguan City(No.2015108101014)Chinese Medicine Science&Technology Foundation of Guangdong Province(No.20151257)+3 种基金Medical Science and Technology Development Foundation of Guangdong Province(No.A2016355)Excellent Young Scientist Training Foundation of Guangdong Province in 2014(No.4CX16054G)Science&Technology Fundation of Guangdong Medical College(No.B2014007)Undergraduate Science&Technology Innovation Foundation of Guangdong Province(Nos.201610571041,201610571015)
文摘Zinc oxide nanoparticles were synthesized using bovine serum albumin as stabilizers through a facile one-pot strategy in aqueous media. The morphology and crystal phase of the zinc oxide nanoparticles were determined by transmission electron microscopy, X-ray diffractograms, and Fourier transform infrared spectroscopy. The synthesized ZnO nanoparticles exhibited strong absorption and photoluminescence properties in the visible wavelength region based on the fluorescence and UV-visible spectroscopy. Based on the results, the zinc oxide nanoparticles could effectively degrade the organic dyes through the mediation of the hydroxyl radical under visible light irradiation. Furthermore, the zinc oxide nanoparticles show good recycling stability during the photocatalytic experiments. These results suggested that the as-prepared zinc oxide nanoparticles might be used as a potential photocatalyst to efficiently treat the organic pollutants.
基金Funded by the Chinese Medicine Science&Technology Foundation of Guangdong Province(No.20151257)Medical Science and Technology Development Foundation of Guangdong Province(No.A2016355)+3 种基金Excellent Young Scientist Training Foundation of Guangdong Province in 2014(No.4CX16054G)Innovation Team Construction Foundationin Ordinary University of Guangdong Province(No.2015KCXTD022)Unique Innovation Foundation in Ordinary University of Guangdong Province(No.2015KTSCX049)Undergraduate Science&Technology Innovation Foundation of Guangdong Province(Nos.201610571041and 201610571015)
文摘Colloidal semiconductor nanoparticles (quantum dots, QDs) have attracted a lot of interests in numerous biological and medical applications due to their potent fluorescent properties. However, the possible toxic effects of quantum dots remain an issue of debate. In this study, we aimed to evaluate the cytocompatibility of bovine serum albumin (BSA) conjugated zinc oxide QDs for C2C12 cells. In the experiment, ZnO QDs were synthesized by using BSA as the structure directing agent, and the morphology and crystal phase of ZnO QDs were determined by transmission electron microscopy, X-ray diffractograms and Fourier transform infrared spectrograph techniques. The inverted fluorescence microscope results showed that ZnO QDs were distributed inside the cells. The toxicity of ZnO QDs was assessed by MTT methods, which revealed that ZnO QDs were highly cytocompatible in the concentration less than 200 μM. However, when the concentration of QDs was higher than 1 000 μM ZnO QDs showed significantly toxicity, which was ascribed to generation of free zinc and formation of reactive oxygen species (ROS). Furthermore, the morphological observations exhibited that cells treated with ZnO QDs showed altered morphology, depolymerized cytoskeleton and irregular-shaped nuclei. This study provides helpful guidances on the future safe use and manipulation of QDs to make them suitable tools in nanomedicine.
