0 INTRODUCTION China's external dependence on oil and gas remains high,making the independent exploration and development of oil and gas resources crucial for ensuring national energy security and the sustainable ...0 INTRODUCTION China's external dependence on oil and gas remains high,making the independent exploration and development of oil and gas resources crucial for ensuring national energy security and the sustainable development of the economy and society.In 2023,China continued to step up its efforts in offshore oil and gas exploration and development,with offshore crude oil production surpassing 62 million tons,accounting for about 70%of the national increase in crude oil production.Deepening offshore oil and gas exploration and development is of great significance for guaranteeing national energy security.展开更多
Acute myeloid leukaemia(AML)is characterized mainly by an increase in the number of myeloid cells in the bone marrow and a decrease in the number of mature cells;AML accounts for 28%of leukaemia cases,and it has a fiv...Acute myeloid leukaemia(AML)is characterized mainly by an increase in the number of myeloid cells in the bone marrow and a decrease in the number of mature cells;AML accounts for 28%of leukaemia cases,and it has a five-year survival rate of only30.5%[1].The prognosis of AML patients is mostly poor,and drug resistance eventually emerges with the long-term use of chemotherapy or targeted therapy;this drug resistance represents a daunting challenge in the management of AML[2,3].展开更多
In recent years, significant advancements have been made in deep-sea broadband seismic acquisition and its support data processing technologies. Compared with traditional constant-depth flat-cable acquisition, variabl...In recent years, significant advancements have been made in deep-sea broadband seismic acquisition and its support data processing technologies. Compared with traditional constant-depth flat-cable acquisition, variable-depth cable acquisition significantly differentiates frequency notches and enhances information complementarity between traces, effectively broadening the frequency band of acquired seismic data. Based on the international slanted cable technology, China has independently developed a plow-type cable seismic acquisition and imaging system: a combination of slanted and deep-deployed flat cables,along with a deghosting processing technique. This innovation optimizes the segmented depth variation of cables, further improving low-frequency response and broadening the high-frequency range. This paper extends the 2D technology into three dimensions, establishing an integrated technology system for deep-sea broadband, wide-azimuth seismic acquisition and imaging, consisting of three-ship and six-source acquisition equipments, 3D plow-type cable mat, blended acquisition design with rolling dual-random sources, and wavenumber-domain 3D deghosting techniques. Applications to two tectonic zones in the South China Sea demonstrate that the frequency band of seismic data is expanded from three octaves(8–85 Hz) by conventional acquisition and imaging methods to five octaves(2–130 Hz), significantly improving the data quality and imaging precision of deep structures. This advancement effectively supports the researches of fundamental geology, hydrocarbon accumulation,reservoir prediction, and fluid identification in deep-water basins. The successful deployment of these technologies has advanced China's deep-sea oil and gas exploration and has been generalized to more than ten international deep-sea oilfields.展开更多
基金supported by the National Science and Technology Major Project(No.2016ZX05024)the Project of Strategic Research and Consulting Projects of the Chinese Academy of Engineering(No.2022-XBZD-08-01)。
文摘0 INTRODUCTION China's external dependence on oil and gas remains high,making the independent exploration and development of oil and gas resources crucial for ensuring national energy security and the sustainable development of the economy and society.In 2023,China continued to step up its efforts in offshore oil and gas exploration and development,with offshore crude oil production surpassing 62 million tons,accounting for about 70%of the national increase in crude oil production.Deepening offshore oil and gas exploration and development is of great significance for guaranteeing national energy security.
基金supported by the National Natural Science Foundation of China(81673466,81821005,32322048,22225702,92153302,32471497,82404655,and 82273951)Guangdong High-level New R&D Institute(2019B090904008)+8 种基金Guangdong High-level Innovative Research Institute(2021B0909050003)Science and Technology Commission of Shanghai Municipality(18431907100 and 19430750100)the National Key Research and Development Program of China(2020YFE0202200)Program of Shanghai Academic Research Leader(2XD1420900)Shanghai Rising-Star Program(22QA1411100)the Youth Innovation Promotion Association(CAS2021276)the support of the Sanofi scholarship program,Shandong Laboratory Program(SYS202205)Taishan Scholars Program(tstp0648)Innovative Research Team of High-level Local Universities in Shanghai,and Shanghai Science and Technology Development Funds(24YF2755300)。
文摘Acute myeloid leukaemia(AML)is characterized mainly by an increase in the number of myeloid cells in the bone marrow and a decrease in the number of mature cells;AML accounts for 28%of leukaemia cases,and it has a five-year survival rate of only30.5%[1].The prognosis of AML patients is mostly poor,and drug resistance eventually emerges with the long-term use of chemotherapy or targeted therapy;this drug resistance represents a daunting challenge in the management of AML[2,3].
基金supported jointly by National Major Science and Technology Project of China (Grant No. 2016ZX05026001)Major Projects for the 14th Five-Year Plan of National Laboratory for Marine Science and Technology (Qingdao) (Grant No. 2021QNLM020001)。
文摘In recent years, significant advancements have been made in deep-sea broadband seismic acquisition and its support data processing technologies. Compared with traditional constant-depth flat-cable acquisition, variable-depth cable acquisition significantly differentiates frequency notches and enhances information complementarity between traces, effectively broadening the frequency band of acquired seismic data. Based on the international slanted cable technology, China has independently developed a plow-type cable seismic acquisition and imaging system: a combination of slanted and deep-deployed flat cables,along with a deghosting processing technique. This innovation optimizes the segmented depth variation of cables, further improving low-frequency response and broadening the high-frequency range. This paper extends the 2D technology into three dimensions, establishing an integrated technology system for deep-sea broadband, wide-azimuth seismic acquisition and imaging, consisting of three-ship and six-source acquisition equipments, 3D plow-type cable mat, blended acquisition design with rolling dual-random sources, and wavenumber-domain 3D deghosting techniques. Applications to two tectonic zones in the South China Sea demonstrate that the frequency band of seismic data is expanded from three octaves(8–85 Hz) by conventional acquisition and imaging methods to five octaves(2–130 Hz), significantly improving the data quality and imaging precision of deep structures. This advancement effectively supports the researches of fundamental geology, hydrocarbon accumulation,reservoir prediction, and fluid identification in deep-water basins. The successful deployment of these technologies has advanced China's deep-sea oil and gas exploration and has been generalized to more than ten international deep-sea oilfields.