Humanoid robots,increasingly recognized for their potential to drive economic and social development,have garnered significant attention in recent years.This paper aims to provide a comprehensive overview of the progr...Humanoid robots,increasingly recognized for their potential to drive economic and social development,have garnered significant attention in recent years.This paper aims to provide a comprehensive overview of the progress,challenges,and future directions in humanoid robotics,with a particular emphasis on essential system components and key technological innovations.Through a review of historical milestones,this paper explores critical aspects such as the design of the head and body,and examines state-of-the-art technologies in areas like locomotion control,perception,and intelligent manipulation.By presenting a thorough analysis of the field,this work aims to serve as a valuable resource for researchers and inspire future innovations that will drive the continued evolution of humanoid robots.展开更多
The treatment of refractory bone defects is a major clinical challenge,especially in steroid-associated osteonecrosis(SAON),which is characterized by insufficient osteogenesis and angiogenesis.Herin,a microenvironment...The treatment of refractory bone defects is a major clinical challenge,especially in steroid-associated osteonecrosis(SAON),which is characterized by insufficient osteogenesis and angiogenesis.Herin,a microenvironment responsiveness scaffold composed of poly-L-lactide(PLLA),and manganese dioxide(MnO_(2))nanoparticles is designed to enhance bone regeneration by scavenging endogenous reactive oxygen species(ROS)and modulating immune microenvironment in situ.A catalase-like catalytic reaction between MnO_(2)and endogenous hydrogen peroxide(H_(2)O_(2))generated at the bone defect area,which typically becomes acidic and ROS-rich,triggers on-demand release of oxygen and M^(n2+),significantly ameliorating inflammatory response by promoting M2-type polarization of macrophages,reprograming osteoimmune microenvironment conducive to angiogenesis and osteogenesis.Furthermore,the fundamental mechanisms were explored through transcriptome sequencing analysis,revealing that PLLA/MnO_(2)scaffolds(PMns)promote osteogenic differentiation by upre-gulating the TGF-β/Smad signaling pathway in human bone marrow mesenchymal stem cells(hBMSCs).Overall,the PMns exhibit superior immunomodulatory,excellent osteogenic-angiogenic properties and promising can-didates as bone graft substitutes for therapy clinical refractory bone defects.展开更多
References Show full outline Cited by(1)Figures(3)Unlabelled figure Fig.1.Population diversity of DNA methylation Fig.2.Genetic contribution to the population differentiation in DNA methylation…Extras(1)Supplementary...References Show full outline Cited by(1)Figures(3)Unlabelled figure Fig.1.Population diversity of DNA methylation Fig.2.Genetic contribution to the population differentiation in DNA methylation…Extras(1)Supplementary Data 1 Elsevier Science Bulletin Volume 70,Issue 5,15 March 2025,Pages 638-642 Science Bulletin Short Communication DNA methylation and genetic regulation in natural populations of East Asian and mixed Eurasian ancestry Author links open overlay panel Shuangshuang Cheng a,Zhilin Ning b,Yan Lu a e,Yuhan Du a,Xiaonan Yang c,Minghui Li c,Dilinuer Maimaitiyiming d,Shuhua Xu a f a State Key Laboratory of Genetic Engineering,Human Phenome Institute,Zhangjiang Fudan International Innovation Center,Center for Evolutionary Biology,School of Life Sciences,Department of Liver Surgery and Transplantation Liver Cancer Institute,Zhongshan Hospital,Fudan University,Shanghai 200032,China b Key Laboratory of Computational Biology,Shanghai Institute of Nutrition and Health,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Shanghai 200031,China c Sinotech Genomics Co.,Ltd.,Shanghai 200120,China d The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China e Ministry of Education Key Laboratory of Contemporary Anthropology,Fudan University,Shanghai 200438,China f School of Life Science and Technology,ShanghaiTech University,Shanghai 201210,China Received 27 March 2024,Revised 16 July 2024,Accepted 30 September 2024,Available online 15 October 2024,Version of Record 10 March 2025.What do these dates mean?Show less Add to Mendeley Share Cite https://doi.org/10.1016/j.scib.2024.10.006 Get rights and content Under a Creative Commons license Open access Graphical abstract Download:Download high-res image(109KB)Download:Download full-size image Previous article Next article As an important epigenetic marker,DNA methylation(DNAm)is a stably inherited epigenetic modification that plays an important role in mammalian epigenetics.DNAm is influenced by genetic and environmental factors[1],and has different functions in different genomic contexts.It has been suggested that a large proportion of DNAm differences are associated with allele frequency divergence[2].In addition,significant differences in cis-DNA methylation quantitative trait loci were found in three Southeast Asian populations[3].The epigenetic structure of DNAm in several populations in China has also been reported recently[4].Some genome-wide studies have identified ancestral origins and population relationships;for example,the Uyghurs have approximately a half-Eastern and half-Western genetic composition[5],[6].Notably,a recent study explored the genetic basis of highly differentiated gene expression with east–west origins in Uyghurs[7].However,our understanding of DNAm profiles and their genetic basis remains limited,particularly in 1:1 mixed-descent populations.In this study,we constructed a DNAm map with data from 92 Uyghurs(XJU)and 33 Han Chinese(HAN)individuals.The procedures followed the ethical standards of the Responsible Committee on Human Experimentation and were approved by the Biomedical Research Ethics Committee of Shanghai Institutes for Biological Sciences(ER-SIBS-261408)and the Helsinki Declaration of 1975(revised in 2000).Each individual was the offspring of a nonconsanguineous marriage of members of the same nationality within three generations.We identified the highly differentiated DNAm positions and regions between HAN and XJU.We then examined the correlation between the level of genetic differences and the level of DNAm differences.Finally,we studied the relationship between the genomic and epigenetic data at the global and local levels.展开更多
Organic ultrathin crystals,comprising monolayers or a few molecular layers,exhibit outstanding optoelectronic properties and have shown great promise for constructing advanced functional neuromorphic devices.However,s...Organic ultrathin crystals,comprising monolayers or a few molecular layers,exhibit outstanding optoelectronic properties and have shown great promise for constructing advanced functional neuromorphic devices.However,scalable growth of high-quality organic ultrathin crystals and their seamless concurrent integration with charge trapping layers for multi-mode neuromorphic devices,that required in future high-density neuromorphic integration,remain challenging.Here,we present a scalable one-step fabrication strategy based on solution shearing,where spontaneous vertical phase separation of a small-molecule/polymer(Ph-BTBT-10/PS)blend enables the simultaneous formation of high-quality ultrathin Ph-BTBT-10 crystals and an electret PS charge-trapping layer.The PS electret layer serves a dual function:it facilitates the formation of ultrathin,highly ordered Ph-BTBT-10 crystals;meanwhile,its gate-tunable electron-trapping capability enables dynamic switching between photo-switching and photo-synaptic modes within a single device.As a photodetector,the device exhibits exceptional performance,including a responsivity of 4.7×10^(4) A/W,specific detectivity of 2.2×10^(17) Jones,and photosensitivity of 1.5×10^(8).Under negative gate bias,light-triggered switching behavior enables logic gate demonstration,while under positive gate modulation,photonic synaptic behavior successfully emulates key biological functions,including excitatory postsynaptic current(EPSC),paired-pulse facilitation(PPF),short-term plasticity(STP)to long-term plasticity(LTP)transition,dynamic learning-forgetting processes,and image processing.Moreover,the system exhibits excellent compatibility with low-voltage flexible substrates and further demonstrates its application in low-consumption flexible neuromorphic devices.This work provides a scalable route toward high-performance,multifunctional neuromorphic optoelectronics based on organic ultrathin crystals,and advances the integration of flexible electronics and brain-inspired computing.展开更多
Mode-division multiplexing(MDM)technology enables high-bandwidth data transmission using orthogonal waveguide modes to construct parallel data streams.However,few demonstrations have been realized for generating and s...Mode-division multiplexing(MDM)technology enables high-bandwidth data transmission using orthogonal waveguide modes to construct parallel data streams.However,few demonstrations have been realized for generating and supporting high-order modes,mainly due to the intrinsic large material groupvelocity dispersion(GVD),which make it challenging to selectively couple different-order spatial modes.We show the feasibility of on-chip GVD engineering by introducing a gradient-index metamaterial structure,which enables a robust and fully scalable MDM process.We demonstrate a record-high-order MDM device that supports TE_(0)–TE_(15)modes simultaneously.40-GBaud 16-ary quadrature amplitude modulation signals encoded on 16 mode channels contribute to a 2.162 Tbit∕s net data rate,which is the highest data rate ever reported for an on-chip single-wavelength transmission.Our method can effectively expand the number of channels provided by MDM technology and promote the emerging research fields with great demand for parallelism,such as high-capacity optical interconnects,high-dimensional quantum communications,and large-scale neural networks.展开更多
Owing to the outstanding properties provided by nontrivial band topology,topological phases of matter are considered as a promising platform towards low-dissipation electronics,efficient spin-charge conversion,and top...Owing to the outstanding properties provided by nontrivial band topology,topological phases of matter are considered as a promising platform towards low-dissipation electronics,efficient spin-charge conversion,and topological quantum computation.Achieving ferroelectricity in topological materials enables the non-volatile control of the quantum states,which could greatly facilitate topological electronic research.However,ferroelectricity is generally incompatible with systems featuring metallicity due to the screening effect of free carriers.In this study,we report the observation of memristive switching based on the ferroelectric surface state of a topological semimetal(TaSe_(4))2I.We find that the surface state of(TaSe_(4))2I presents out-of-plane ferroelectric polarization due to surface reconstruction.With the combination of ferroelectric surface and charge-density-wave-gapped bulk states,an electric-switchable barrier height can be achieved in(TaSe_(4))2I-metal contact.By employing a multi-terminal-grounding design,we manage to construct a prototype ferroelectric memristor based on(TaSe_(4))2I with on/off ratio up to 103,endurance over 103 cycles,and good retention characteristics.The origin of the ferroelectric surface state is further investigated by first-principles calculations,which reveal an interplay between ferroelectricity and band topology.The emergence of ferroelectricity in(TaSe_(4))2I not only demonstrates it as a rare but essential case of ferroelectric topological materials,but also opens new routes towards the implementation of topological materials in functional electronic devices.展开更多
In the scheme of fast ignition of inertial confinement fusion,the fuel temperature mainly relies on fast electrons,which act as an energy carrier,transferring the laser energy to the fuel.Both conversion efficiency fr...In the scheme of fast ignition of inertial confinement fusion,the fuel temperature mainly relies on fast electrons,which act as an energy carrier,transferring the laser energy to the fuel.Both conversion efficiency from the laser to the fast electron and the energy spectrum of the fast electron are essentially important to achieve highly effective heating.In this study,a two-dimensional particle in cell simulation is applied to study the generation of fast electrons from solid-density plasmas with different laser waveforms.The results have shown that the slope of the rising edge has a significant effect on fast electron generation and energy absorption.For the negative skew pulse with a relatively slow rising edge,the J×B mechanism can most effectively accelerate the electrons.The overall absorption efficiency of the laser energy is optimized,and the fast electron yield in the middle-and low-energy range is also improved.展开更多
Compression-absorption cascade refrigeration cycle(CACRC)combined with vapor-compression refrigeration and absorption refrigeration cycle attracts great interest due to the less electricity consumption and utilization...Compression-absorption cascade refrigeration cycle(CACRC)combined with vapor-compression refrigeration and absorption refrigeration cycle attracts great interest due to the less electricity consumption and utilization waste heat.In this work,the performance of the CACRC system was investigated using 16 refrigerants in the vapor compression section and H_(2)O-LiBr in the absorption refrigeration section.Energy,exergy and economic analysis of the CACRC system were carried out and the results were compared.Results show that RE170/H_(2)O-LiBr presents the better coefficient of performance and exergy efficiency amongst all the studied fluids.In addition,the economic optimization,multi-objective optimization,and thermodynamic optimization of the CACRC system based on the RE170/H_(2)O-LiBr working fluid were also carried out.展开更多
文摘Humanoid robots,increasingly recognized for their potential to drive economic and social development,have garnered significant attention in recent years.This paper aims to provide a comprehensive overview of the progress,challenges,and future directions in humanoid robotics,with a particular emphasis on essential system components and key technological innovations.Through a review of historical milestones,this paper explores critical aspects such as the design of the head and body,and examines state-of-the-art technologies in areas like locomotion control,perception,and intelligent manipulation.By presenting a thorough analysis of the field,this work aims to serve as a valuable resource for researchers and inspire future innovations that will drive the continued evolution of humanoid robots.
基金financially supported by the National Natural Science Foundation of China(81871767)Shenzhen Medical Research Funds(B2302050)+4 种基金Guangdong Basic and Applied Basic Research Foundation(No.2022B1515120046,2023A1515010087,2023A1515011315)Shenzhen Key Laboratory of Digital Surgical Printing Project(ZDSYS201707311542415)Shenzhen Science and Technology Program(JCYJ20220818103417037,JCYJ20210324115814040,JCYJ 20210324102206016,JSGG20210629144538010,KJZD20230923115200002)Shenzhen Development and Reform Program(XMHT20220106001)the Shenzhen Basic Research General Project(JCYJ20220531100408019).
文摘The treatment of refractory bone defects is a major clinical challenge,especially in steroid-associated osteonecrosis(SAON),which is characterized by insufficient osteogenesis and angiogenesis.Herin,a microenvironment responsiveness scaffold composed of poly-L-lactide(PLLA),and manganese dioxide(MnO_(2))nanoparticles is designed to enhance bone regeneration by scavenging endogenous reactive oxygen species(ROS)and modulating immune microenvironment in situ.A catalase-like catalytic reaction between MnO_(2)and endogenous hydrogen peroxide(H_(2)O_(2))generated at the bone defect area,which typically becomes acidic and ROS-rich,triggers on-demand release of oxygen and M^(n2+),significantly ameliorating inflammatory response by promoting M2-type polarization of macrophages,reprograming osteoimmune microenvironment conducive to angiogenesis and osteogenesis.Furthermore,the fundamental mechanisms were explored through transcriptome sequencing analysis,revealing that PLLA/MnO_(2)scaffolds(PMns)promote osteogenic differentiation by upre-gulating the TGF-β/Smad signaling pathway in human bone marrow mesenchymal stem cells(hBMSCs).Overall,the PMns exhibit superior immunomodulatory,excellent osteogenic-angiogenic properties and promising can-didates as bone graft substitutes for therapy clinical refractory bone defects.
基金National Key Research and Development Program of China(2023YFC2605400)National Natural Science Foundation of China(32030020,32288101,and 32470649)+2 种基金Shanghai Science and Technology Commission Program(23JS1410100)Office of Global Partnerships(Key Projects Development Fund)The computational work in this study was supported by the CFFF Computing Platform of Fudan University.The funders had no role in the study design,data collection,analysis,decision to publish,or preparation of the manuscript.
文摘References Show full outline Cited by(1)Figures(3)Unlabelled figure Fig.1.Population diversity of DNA methylation Fig.2.Genetic contribution to the population differentiation in DNA methylation…Extras(1)Supplementary Data 1 Elsevier Science Bulletin Volume 70,Issue 5,15 March 2025,Pages 638-642 Science Bulletin Short Communication DNA methylation and genetic regulation in natural populations of East Asian and mixed Eurasian ancestry Author links open overlay panel Shuangshuang Cheng a,Zhilin Ning b,Yan Lu a e,Yuhan Du a,Xiaonan Yang c,Minghui Li c,Dilinuer Maimaitiyiming d,Shuhua Xu a f a State Key Laboratory of Genetic Engineering,Human Phenome Institute,Zhangjiang Fudan International Innovation Center,Center for Evolutionary Biology,School of Life Sciences,Department of Liver Surgery and Transplantation Liver Cancer Institute,Zhongshan Hospital,Fudan University,Shanghai 200032,China b Key Laboratory of Computational Biology,Shanghai Institute of Nutrition and Health,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Shanghai 200031,China c Sinotech Genomics Co.,Ltd.,Shanghai 200120,China d The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China e Ministry of Education Key Laboratory of Contemporary Anthropology,Fudan University,Shanghai 200438,China f School of Life Science and Technology,ShanghaiTech University,Shanghai 201210,China Received 27 March 2024,Revised 16 July 2024,Accepted 30 September 2024,Available online 15 October 2024,Version of Record 10 March 2025.What do these dates mean?Show less Add to Mendeley Share Cite https://doi.org/10.1016/j.scib.2024.10.006 Get rights and content Under a Creative Commons license Open access Graphical abstract Download:Download high-res image(109KB)Download:Download full-size image Previous article Next article As an important epigenetic marker,DNA methylation(DNAm)is a stably inherited epigenetic modification that plays an important role in mammalian epigenetics.DNAm is influenced by genetic and environmental factors[1],and has different functions in different genomic contexts.It has been suggested that a large proportion of DNAm differences are associated with allele frequency divergence[2].In addition,significant differences in cis-DNA methylation quantitative trait loci were found in three Southeast Asian populations[3].The epigenetic structure of DNAm in several populations in China has also been reported recently[4].Some genome-wide studies have identified ancestral origins and population relationships;for example,the Uyghurs have approximately a half-Eastern and half-Western genetic composition[5],[6].Notably,a recent study explored the genetic basis of highly differentiated gene expression with east–west origins in Uyghurs[7].However,our understanding of DNAm profiles and their genetic basis remains limited,particularly in 1:1 mixed-descent populations.In this study,we constructed a DNAm map with data from 92 Uyghurs(XJU)and 33 Han Chinese(HAN)individuals.The procedures followed the ethical standards of the Responsible Committee on Human Experimentation and were approved by the Biomedical Research Ethics Committee of Shanghai Institutes for Biological Sciences(ER-SIBS-261408)and the Helsinki Declaration of 1975(revised in 2000).Each individual was the offspring of a nonconsanguineous marriage of members of the same nationality within three generations.We identified the highly differentiated DNAm positions and regions between HAN and XJU.We then examined the correlation between the level of genetic differences and the level of DNAm differences.Finally,we studied the relationship between the genomic and epigenetic data at the global and local levels.
基金supported by the National Key Research and Development Program of China(2022YFB3607500)the National Natural Science Foundation of China(52373194,52403301,and 62274076)the Haihe Laboratory of Sustainable Chemical Transformations.
文摘Organic ultrathin crystals,comprising monolayers or a few molecular layers,exhibit outstanding optoelectronic properties and have shown great promise for constructing advanced functional neuromorphic devices.However,scalable growth of high-quality organic ultrathin crystals and their seamless concurrent integration with charge trapping layers for multi-mode neuromorphic devices,that required in future high-density neuromorphic integration,remain challenging.Here,we present a scalable one-step fabrication strategy based on solution shearing,where spontaneous vertical phase separation of a small-molecule/polymer(Ph-BTBT-10/PS)blend enables the simultaneous formation of high-quality ultrathin Ph-BTBT-10 crystals and an electret PS charge-trapping layer.The PS electret layer serves a dual function:it facilitates the formation of ultrathin,highly ordered Ph-BTBT-10 crystals;meanwhile,its gate-tunable electron-trapping capability enables dynamic switching between photo-switching and photo-synaptic modes within a single device.As a photodetector,the device exhibits exceptional performance,including a responsivity of 4.7×10^(4) A/W,specific detectivity of 2.2×10^(17) Jones,and photosensitivity of 1.5×10^(8).Under negative gate bias,light-triggered switching behavior enables logic gate demonstration,while under positive gate modulation,photonic synaptic behavior successfully emulates key biological functions,including excitatory postsynaptic current(EPSC),paired-pulse facilitation(PPF),short-term plasticity(STP)to long-term plasticity(LTP)transition,dynamic learning-forgetting processes,and image processing.Moreover,the system exhibits excellent compatibility with low-voltage flexible substrates and further demonstrates its application in low-consumption flexible neuromorphic devices.This work provides a scalable route toward high-performance,multifunctional neuromorphic optoelectronics based on organic ultrathin crystals,and advances the integration of flexible electronics and brain-inspired computing.
基金supported by the National Key R&D Program of China(Grant No.2021YFB2800103)National Natural Science Foundation of China(NSFC)(Grant Nos.62105202,61835008,61860206001,61975115,62035016,and 62105200).
文摘Mode-division multiplexing(MDM)technology enables high-bandwidth data transmission using orthogonal waveguide modes to construct parallel data streams.However,few demonstrations have been realized for generating and supporting high-order modes,mainly due to the intrinsic large material groupvelocity dispersion(GVD),which make it challenging to selectively couple different-order spatial modes.We show the feasibility of on-chip GVD engineering by introducing a gradient-index metamaterial structure,which enables a robust and fully scalable MDM process.We demonstrate a record-high-order MDM device that supports TE_(0)–TE_(15)modes simultaneously.40-GBaud 16-ary quadrature amplitude modulation signals encoded on 16 mode channels contribute to a 2.162 Tbit∕s net data rate,which is the highest data rate ever reported for an on-chip single-wavelength transmission.Our method can effectively expand the number of channels provided by MDM technology and promote the emerging research fields with great demand for parallelism,such as high-capacity optical interconnects,high-dimensional quantum communications,and large-scale neural networks.
基金supported by the National Key R&D Program of China(2022YFA1405700)the National Natural Science Foundation of China(12174069 and 92365104)+8 种基金Shuguang Program from the Shanghai Education Development Foundationsupported by the National Key R&D Program of China(2023YFA1407500)the National Natural Science Foundation of China(12174104 and 62005079)supported by the National Key R&D Program of China(2022YFA1402901)National Natural Science Foundation of China(12274082)Shanghai Science and Technology Committee(23ZR1406600)Shanghai Pilot Program for Basic Research-FuDan University 21TQ1400100(23TQ017)supported by the China Postdoctoral Science Foundation(2022M720816)supported by the National Key R&D Program of China(2022YFA1402902)。
文摘Owing to the outstanding properties provided by nontrivial band topology,topological phases of matter are considered as a promising platform towards low-dissipation electronics,efficient spin-charge conversion,and topological quantum computation.Achieving ferroelectricity in topological materials enables the non-volatile control of the quantum states,which could greatly facilitate topological electronic research.However,ferroelectricity is generally incompatible with systems featuring metallicity due to the screening effect of free carriers.In this study,we report the observation of memristive switching based on the ferroelectric surface state of a topological semimetal(TaSe_(4))2I.We find that the surface state of(TaSe_(4))2I presents out-of-plane ferroelectric polarization due to surface reconstruction.With the combination of ferroelectric surface and charge-density-wave-gapped bulk states,an electric-switchable barrier height can be achieved in(TaSe_(4))2I-metal contact.By employing a multi-terminal-grounding design,we manage to construct a prototype ferroelectric memristor based on(TaSe_(4))2I with on/off ratio up to 103,endurance over 103 cycles,and good retention characteristics.The origin of the ferroelectric surface state is further investigated by first-principles calculations,which reveal an interplay between ferroelectricity and band topology.The emergence of ferroelectricity in(TaSe_(4))2I not only demonstrates it as a rare but essential case of ferroelectric topological materials,but also opens new routes towards the implementation of topological materials in functional electronic devices.
基金supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(Nos.XDA25030100 and XDA25051000)the National Natural Science Foundation of China(Nos.U1930107 and 11827807)。
文摘In the scheme of fast ignition of inertial confinement fusion,the fuel temperature mainly relies on fast electrons,which act as an energy carrier,transferring the laser energy to the fuel.Both conversion efficiency from the laser to the fast electron and the energy spectrum of the fast electron are essentially important to achieve highly effective heating.In this study,a two-dimensional particle in cell simulation is applied to study the generation of fast electrons from solid-density plasmas with different laser waveforms.The results have shown that the slope of the rising edge has a significant effect on fast electron generation and energy absorption.For the negative skew pulse with a relatively slow rising edge,the J×B mechanism can most effectively accelerate the electrons.The overall absorption efficiency of the laser energy is optimized,and the fast electron yield in the middle-and low-energy range is also improved.
基金supported by the National Natural Science Foundation of China(Grant No.:51936009).
文摘Compression-absorption cascade refrigeration cycle(CACRC)combined with vapor-compression refrigeration and absorption refrigeration cycle attracts great interest due to the less electricity consumption and utilization waste heat.In this work,the performance of the CACRC system was investigated using 16 refrigerants in the vapor compression section and H_(2)O-LiBr in the absorption refrigeration section.Energy,exergy and economic analysis of the CACRC system were carried out and the results were compared.Results show that RE170/H_(2)O-LiBr presents the better coefficient of performance and exergy efficiency amongst all the studied fluids.In addition,the economic optimization,multi-objective optimization,and thermodynamic optimization of the CACRC system based on the RE170/H_(2)O-LiBr working fluid were also carried out.