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白花蛇舌草提取液对日光性皮炎小鼠的保护作用及机制研究
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作者 马悦文 李小静 +2 位作者 黄雪锋 陈贤 王春丽 《日用化学工业(中英文)》 北大核心 2025年第5期581-590,共10页
研究白花蛇舌草提取液对紫外线B(UVB)诱导的日光性皮炎小鼠的抗氧化和抗炎作用。使用KM小鼠进行UVB照射7天,同时外涂质量分数1%和2%的白花蛇舌草提取液进行治疗。对小鼠皮肤组织进行苏木精-伊红染色(HE)染色、苦味酸-酸性品红法(VG)染... 研究白花蛇舌草提取液对紫外线B(UVB)诱导的日光性皮炎小鼠的抗氧化和抗炎作用。使用KM小鼠进行UVB照射7天,同时外涂质量分数1%和2%的白花蛇舌草提取液进行治疗。对小鼠皮肤组织进行苏木精-伊红染色(HE)染色、苦味酸-酸性品红法(VG)染色观察小鼠皮肤状态。通过生化和免疫组化检测皮肤组织中氧化应激指标NOS、NO、T-SOD以及炎症指标TNF-α、IL-6、IL-1β水平,通过qRT-PCR和Western blotting检测皮肤组织中Nrf2、Keap1、HO-1、NQO1、GCLC、NF-κB、HMGB1、p65的mRNA或蛋白表达水平。结果表明,与UVB组对比,白花蛇舌草提取液1%组和2%组小鼠皮肤损伤程度有所改善,胶原纤维排列整齐,胶原密度升高,NOS、NO水平降低、T-SOD水平提高,TNF-α、IL-6、IL-1β表达水平降低,皮肤组织中Nrf2、Keap1、HO-1、NQO1、GCLC的mRNA表达水平升高,NF-κB、HMGB1 mRNA表达水平降低,皮肤组织中Nrf2、Keap1、HO-1、NQO1、GCLC、p65的蛋白相对表达量升高,HMGB1的蛋白表达水平降低。可见,白花蛇舌草提取液可以改善UVB介导的小鼠日光性皮炎,其抗氧化抗炎机制可能与Nrf2和NF-κB信号通路有关。 展开更多
关键词 白花蛇舌草提取液 紫外线B 日光性皮炎 抗氧化 抗炎
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TexPro:Text-guided PBR texturing with procedural material modeling
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作者 Ziqiang Dang Wenqi Dong +4 位作者 Zesong Yang Bangbang Yang Liang Li yuewen ma Zhaopeng Cui 《Computational Visual Media》 2025年第4期745-761,共17页
In this paper,we present TexPro,a novel method for high-fidelity material generation for input 3D meshes given text prompts.Unlike existing text-conditioned texture generation methods that typically generate RGB textu... In this paper,we present TexPro,a novel method for high-fidelity material generation for input 3D meshes given text prompts.Unlike existing text-conditioned texture generation methods that typically generate RGB textures with baked lighting,TexPro is able to produce diverse texture maps via procedural material modeling,which enables physically-based rendering,relighting,and additional benefits inherent to procedural materials.Specifically,we first generate multi-view reference images given the input textual prompt by employing the latest text-to-image model.We then derive texture maps through rendering-based optimization with recent differentiable procedural materials.To this end,we design several techniques to handle the misalignment between the generated multi-view images and 3D meshes,and introduce a novel material agent that enhances material classification and matching by exploring both part-level understanding and object-aware material reasoning.Experiments demonstrate the superiority of the proposed method over existing SOTAs,and its capability of relighting. 展开更多
关键词 3D asset creation text-guided texturing procedural materials multi-modal large language model(MLLM)
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AvatarWild:Fully controllable head avatars in the wild
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作者 Shaoxu Meng Tong Wu +4 位作者 Fang-Lue Zhang Shu-Yu Chen yuewen ma Wenbo Hu Lin Gao 《Visual Informatics》 EI 2024年第3期96-106,共11页
Recent advancements in the field have resulted in significant progress in achieving realistic head reconstruction and manipulation using neural radiance fields(NeRF).Despite these advances,capturing intricate facial d... Recent advancements in the field have resulted in significant progress in achieving realistic head reconstruction and manipulation using neural radiance fields(NeRF).Despite these advances,capturing intricate facial details remains a persistent challenge.Moreover,casually captured input,involving both head poses and camera movements,introduces additional difficulties to existing methods of head avatar reconstruction.To address the challenge posed by video data captured with camera motion,we propose a novel method,AvatarWild,for reconstructing head avatars from monocular videos taken by consumer devices.Notably,our approach decouples the camera pose and head pose,allowing reconstructed avatars to be visualized with different poses and expressions from novel viewpoints.To enhance the visual quality of the reconstructed facial avatar,we introduce a view-dependent detail enhancement module designed to augment local facial details without compromising viewpoint consistency.Our method demonstrates superior performance compared to existing approaches,as evidenced by reconstruction and animation results on both multi-view and single-view datasets.Remarkably,our approach stands out by exclusively relying on video data captured by portable devices,such as smartphones.This not only underscores the practicality of our method but also extends its applicability to real-world scenarios where accessibility and ease of data capture are crucial. 展开更多
关键词 Neural radiance fields Head avatar synthesis Face reconstruction Face reenactment Facial animation
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