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Laser polarization-variable autofluorescence of the network of optically anisotropic biological tissues:Diagnostics and differentiation of early stages of cancer of cervia uteri
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作者 Yu.A.Ushenko M.I.Sidor +3 位作者 N.Pashkovskaia G.D.Koval yu.f.marchuk D.Andreichuk 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2014年第3期98-107,共10页
This research presents the results of investigation of laser_polarization fluorescence ofbiological layers(histological sections,cy tological smears)in the task of diagnostics and differ-en tiation of early stages of ... This research presents the results of investigation of laser_polarization fluorescence ofbiological layers(histological sections,cy tological smears)in the task of diagnostics and differ-en tiation of early stages of cancer:Dysplasia-cervical microinvasive carcinoma of cervic uteri.The analytical conditions of polarization-optimal probing of biological layers were determinedbasing on the model of linear birefringence and dichroism of birefringent(fibrllar,porphyrin)networks.The technique of polarization-variable laser autofluorescence was developed andexperimentally tested.The objective criteria(statistical moments)of differentiation of histo-logical sections autofluorescent images of endometrium biopsy and cytological smears of itmucous coat were defined.The operational characteristics(sensitivity,speifity,accuracy)ofthis technique were determined concerning the positions of probative medicine,and clinical efficiency. 展开更多
关键词 AUTOFLUORESCENCE POLARIZATION BIREFRINGENCE statistical optics DIAGNOSTICS medical and autofluorescence imaging.
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