b The discharge performance of Mg-Al-Pb-La anode was investigated by electrochemical techniques and compared withthat of Mg-Al-Pb alloy. The results indicate that the Mg-Al-Pb-La anode provides enhanced corrosion resi...b The discharge performance of Mg-Al-Pb-La anode was investigated by electrochemical techniques and compared withthat of Mg-Al-Pb alloy. The results indicate that the Mg-Al-Pb-La anode provides enhanced corrosion resistance at open circlepotential, and exhibits better discharge activity than the Mg-Al-Pb alloy. The utilization efficiency of Mg-Al-Pb-La anode ishigher than that of commercial Mg-Al-Zn （AZ） and Mg-Al-Mn （AM） alloys. A single Mg-air battery with Mg-Al-Pb-La alloy asthe anode and air as the cathode has an average discharge potential of 1.295 V and a discharge capacity of 1370 mA·h/g duringdischarge at 10 mA/cm2, which is higher than that of batteries using Mg-Li anodes. The enhancement in discharge performance ofthe Mg-Al-Pb-La anode is caused by its modified microstructure, which reduces the self-corrosion and accelerates the spalling ofoxidation products during battery discharge. Furthermore, the dissolution mechanism of Mg-Al-Pb-La anode during the dischargeprocess was analyzed.展开更多
The phenotypes of protein and amino acid contents were measured in an F9 recombinant inbred line population derived from a cross between Zhenshan 97B and Delong 208. A total of 48 and 64 QTLs were identified in 2004 a...The phenotypes of protein and amino acid contents were measured in an F9 recombinant inbred line population derived from a cross between Zhenshan 97B and Delong 208. A total of 48 and 64 QTLs were identified in 2004 and 2005, respectively. The contribution of each QTL to the phenotypic variation ranged from 4.0% to 43.7%. Most QTLs co-localized, forming 29 QTL clusters on the chromosomes with three major ones detected in both years, which were mapped on chromosomes 1, 7 and 9, respectively. The two QTL clusters for amino acid content, qAa1 and qAa7, influenced almost all the traits with the allele from Zhenshan 97B, and the third QTL cluster for amino acid content, qAa9, increased the lysine content with the allele from Delong 208. A wide coincidence was found between the QTL detected under this study and the loci involved in amino acid metabolism pathways in nitrogen assimilation and transport, or protein biosynthesis. The results would facilitate the identification of candidate genes and could be used in marker-assisted selection for the favorable allele in rice quality improvement.展开更多
A biodegradable Mg−2Zn−0.4Sc−0.2Zr(ZK20−0.4Sc)alloy wire with a diameter of 0.5 mm was prepared by a combination of hot extrusion and cold-drawing.The average grain size of ZK20−0.4Sc alloy wire on the longitudinal se...A biodegradable Mg−2Zn−0.4Sc−0.2Zr(ZK20−0.4Sc)alloy wire with a diameter of 0.5 mm was prepared by a combination of hot extrusion and cold-drawing.The average grain size of ZK20−0.4Sc alloy wire on the longitudinal section along the drawing direction is approximately 7.3μm.The texture results show relatively strong<1020>and weak<1010>fiber texture components parallel to the drawing direction.The ZK20−0.4Sc alloy wire exhibits better mechanical properties with the tensile strength,yield strength and elongate of(329±2)MPa,(287±2)MPa and(14.2±0.5)%,respectively.The better mechanical properties are mainly attributed to the grain refinement strengthening,dislocation strengthening and precipitation strengthening.With the immersion time increasing to 14 d,the corrosion type transfers from filament corrosion and pitting corrosion to severe localized corrosion.展开更多
Dyskeratosis follicularis (Darier’s disease, DD) is rare autosomal dominant disease characterized by hyperkeratotic papules that coalesce into plaques and occur primarily in seborrheic or intertriginous areas. Associ...Dyskeratosis follicularis (Darier’s disease, DD) is rare autosomal dominant disease characterized by hyperkeratotic papules that coalesce into plaques and occur primarily in seborrheic or intertriginous areas. Associated findings include nail abnormalities. A 3-year-old boy presented with porcupine-like appearance for 2 years. The lesion from the back was taken for light microscopy and electron microscopy. He was treated with acitretin (0.31 mg/d to 0.66 mg/d) for 8 years. Light microscopy and electron microscopy showed that the typical features of DD. The patient show good respond to the treatment. During 8 years treatment, the patient had dry mouth and pruritus. The skeletal abnormalities didn’t happen in the patient. The serum lipid profile, liver function and renal function within normal lever after treatment. Our findings showed that porcupine-like appearance is a unique pattern of DD. Acitretin may be a useful therapeutic agent in children with DD and less likely to cause skeletal problems.展开更多
Objective:To study the effect of intense pulsed light autopulse combined with oral metronidazole on serum inflammatory mediators in patients with mild and moderate acne. Methods: A total of 84 patients who were diagno...Objective:To study the effect of intense pulsed light autopulse combined with oral metronidazole on serum inflammatory mediators in patients with mild and moderate acne. Methods: A total of 84 patients who were diagnosed with mild-to-moderate acne in our hospital between May 2013 and December 2015 were selected and randomly divided into laser group and metronidazole group who received intense pulsed light autopulse combined with oral metronidazole therapy and oral metronidazole monotherapy respectively. Before treatment as well as 1 week and 2 weeks after treatment, the serum was collected, fluorescent quantitative PCR kits were used to determine the expression of TLR molecules and NLRP inflammasome, and enzyme-linked immunosorbent assay kits were used to determine the levels of inflammatory cytokines.Results: 2 weeks and 4 weeks after treatment, serum IL-1β, IL-8, IL-12 and IL-18 levels as well as TLR2, TLR4, NLRP3, ASC and Caspase-1 mRNA expression of both groups of patients were significantly lower than those before treatment, and serum IL-1β, IL-8, IL-12 and IL-18 levels as well as TLR2, TLR4, NLRP3, ASC and Caspase-1 mRNA expression of laser group were significantly lower than those of metronidazole group.Conclusion: Intense pulsed light autopulse combined with oral metronidazole has significant inhibitory effect on the inflammatory response mediated by pattern recognition receptors TLR2, TLR4 and NLRP3 in patients with mild and moderate acne.展开更多
基金Project(2015JC3004)supported by the Science and Technology Plan of Hunan Province,ChinaProject(2016JJ2147)supported by the Natural Science Foundation of Hunan Province,ChinaProject(51401243)supported by the National Natural Science Foundation of China
文摘b The discharge performance of Mg-Al-Pb-La anode was investigated by electrochemical techniques and compared withthat of Mg-Al-Pb alloy. The results indicate that the Mg-Al-Pb-La anode provides enhanced corrosion resistance at open circlepotential, and exhibits better discharge activity than the Mg-Al-Pb alloy. The utilization efficiency of Mg-Al-Pb-La anode ishigher than that of commercial Mg-Al-Zn （AZ） and Mg-Al-Mn （AM） alloys. A single Mg-air battery with Mg-Al-Pb-La alloy asthe anode and air as the cathode has an average discharge potential of 1.295 V and a discharge capacity of 1370 mA·h/g duringdischarge at 10 mA/cm2, which is higher than that of batteries using Mg-Li anodes. The enhancement in discharge performance ofthe Mg-Al-Pb-La anode is caused by its modified microstructure, which reduces the self-corrosion and accelerates the spalling ofoxidation products during battery discharge. Furthermore, the dissolution mechanism of Mg-Al-Pb-La anode during the dischargeprocess was analyzed.
基金supported by grants from the National Program on the Development of Basic Research (Grant No. 2011CB100200)the National Program of High Technology Development (Grant No. 2010AA101801)+1 种基金the National Program of Plant Transgenic Breeding (Grant No. 2008ZX08009-003)the National Natural Science Foundation of China (Grant No. 30671114)
文摘The phenotypes of protein and amino acid contents were measured in an F9 recombinant inbred line population derived from a cross between Zhenshan 97B and Delong 208. A total of 48 and 64 QTLs were identified in 2004 and 2005, respectively. The contribution of each QTL to the phenotypic variation ranged from 4.0% to 43.7%. Most QTLs co-localized, forming 29 QTL clusters on the chromosomes with three major ones detected in both years, which were mapped on chromosomes 1, 7 and 9, respectively. The two QTL clusters for amino acid content, qAa1 and qAa7, influenced almost all the traits with the allele from Zhenshan 97B, and the third QTL cluster for amino acid content, qAa9, increased the lysine content with the allele from Delong 208. A wide coincidence was found between the QTL detected under this study and the loci involved in amino acid metabolism pathways in nitrogen assimilation and transport, or protein biosynthesis. The results would facilitate the identification of candidate genes and could be used in marker-assisted selection for the favorable allele in rice quality improvement.
基金financial support from the National Nature Science Foundation of China (No.52274369)the Hunan Provincial Natural Science Foundation,China (No.2024JJ6521)。
文摘A biodegradable Mg−2Zn−0.4Sc−0.2Zr(ZK20−0.4Sc)alloy wire with a diameter of 0.5 mm was prepared by a combination of hot extrusion and cold-drawing.The average grain size of ZK20−0.4Sc alloy wire on the longitudinal section along the drawing direction is approximately 7.3μm.The texture results show relatively strong<1020>and weak<1010>fiber texture components parallel to the drawing direction.The ZK20−0.4Sc alloy wire exhibits better mechanical properties with the tensile strength,yield strength and elongate of(329±2)MPa,(287±2)MPa and(14.2±0.5)%,respectively.The better mechanical properties are mainly attributed to the grain refinement strengthening,dislocation strengthening and precipitation strengthening.With the immersion time increasing to 14 d,the corrosion type transfers from filament corrosion and pitting corrosion to severe localized corrosion.
文摘Dyskeratosis follicularis (Darier’s disease, DD) is rare autosomal dominant disease characterized by hyperkeratotic papules that coalesce into plaques and occur primarily in seborrheic or intertriginous areas. Associated findings include nail abnormalities. A 3-year-old boy presented with porcupine-like appearance for 2 years. The lesion from the back was taken for light microscopy and electron microscopy. He was treated with acitretin (0.31 mg/d to 0.66 mg/d) for 8 years. Light microscopy and electron microscopy showed that the typical features of DD. The patient show good respond to the treatment. During 8 years treatment, the patient had dry mouth and pruritus. The skeletal abnormalities didn’t happen in the patient. The serum lipid profile, liver function and renal function within normal lever after treatment. Our findings showed that porcupine-like appearance is a unique pattern of DD. Acitretin may be a useful therapeutic agent in children with DD and less likely to cause skeletal problems.
文摘Objective:To study the effect of intense pulsed light autopulse combined with oral metronidazole on serum inflammatory mediators in patients with mild and moderate acne. Methods: A total of 84 patients who were diagnosed with mild-to-moderate acne in our hospital between May 2013 and December 2015 were selected and randomly divided into laser group and metronidazole group who received intense pulsed light autopulse combined with oral metronidazole therapy and oral metronidazole monotherapy respectively. Before treatment as well as 1 week and 2 weeks after treatment, the serum was collected, fluorescent quantitative PCR kits were used to determine the expression of TLR molecules and NLRP inflammasome, and enzyme-linked immunosorbent assay kits were used to determine the levels of inflammatory cytokines.Results: 2 weeks and 4 weeks after treatment, serum IL-1β, IL-8, IL-12 and IL-18 levels as well as TLR2, TLR4, NLRP3, ASC and Caspase-1 mRNA expression of both groups of patients were significantly lower than those before treatment, and serum IL-1β, IL-8, IL-12 and IL-18 levels as well as TLR2, TLR4, NLRP3, ASC and Caspase-1 mRNA expression of laser group were significantly lower than those of metronidazole group.Conclusion: Intense pulsed light autopulse combined with oral metronidazole has significant inhibitory effect on the inflammatory response mediated by pattern recognition receptors TLR2, TLR4 and NLRP3 in patients with mild and moderate acne.
