Objective:Acupuncture methods(including moxibustion)are used frequently in the treatment of herpes zoster.However,the choice is usually made only based on personal experience among different acupuncture methods.This s...Objective:Acupuncture methods(including moxibustion)are used frequently in the treatment of herpes zoster.However,the choice is usually made only based on personal experience among different acupuncture methods.This study compared the effectiveness of different acupuncture methods for herpes zoster.Methods:All randomized controlled trials(RCTs)of acupuncture methods for herpes zoster were searched in seven databases including Cochrane Library,Embase,PubMed,Web of Science,Wan-fang,CNKI,and CQVIP database.After screening process,effectiveness rate was extracted from all the included RCTs as primary outcomes.The Bayesian network meta-analysis was conducted by GeMTC 0.14.3,Stata13.0 and Review Man 5.3.Results:39 studies were included,which contained 3,042 participants among 11 interventions.Based on the results of network meta-analysis and ranking probability,fire-acupuncture plus electro-acupuncture is considered to be the most effective method,followed by body-acupuncture plus moxibustion,fire-acupuncture,surround-acupuncture plus moxibustion,moxibustion,surround-acupuncture plus western medicine,surround-acupuncture plus electro-acupuncture,body-acupuncture plus western medicine,surround-acupuncture,western medicine,body-acupuncture.Global and local inconsistency test suggested no significant difference between the results of direct and indirect comparisons.Conclusion:Acupuncture methods might be an effective alternative treatment for herpes zoster and fire-acupuncture plus electro-acupuncture might be considered the best option among the included treatments.However,the results of this study need to be interpreted with caution,because there may still be a problem of small sample size of some studies and interventions.Future research,with a standard methodology and design,requires large-scale trials to validate the effect identified in this meta-analysis.展开更多
基金This study is supported by the Natural Science Foundation of Guangdong,China(2020A1515010756)Project of Administration of Traditional Chinese Medicine of Guangdong Province of China(No.20201074 and No.20221103)the Fundamental Research Funds for the Central Universities(No.21621001).
文摘Objective:Acupuncture methods(including moxibustion)are used frequently in the treatment of herpes zoster.However,the choice is usually made only based on personal experience among different acupuncture methods.This study compared the effectiveness of different acupuncture methods for herpes zoster.Methods:All randomized controlled trials(RCTs)of acupuncture methods for herpes zoster were searched in seven databases including Cochrane Library,Embase,PubMed,Web of Science,Wan-fang,CNKI,and CQVIP database.After screening process,effectiveness rate was extracted from all the included RCTs as primary outcomes.The Bayesian network meta-analysis was conducted by GeMTC 0.14.3,Stata13.0 and Review Man 5.3.Results:39 studies were included,which contained 3,042 participants among 11 interventions.Based on the results of network meta-analysis and ranking probability,fire-acupuncture plus electro-acupuncture is considered to be the most effective method,followed by body-acupuncture plus moxibustion,fire-acupuncture,surround-acupuncture plus moxibustion,moxibustion,surround-acupuncture plus western medicine,surround-acupuncture plus electro-acupuncture,body-acupuncture plus western medicine,surround-acupuncture,western medicine,body-acupuncture.Global and local inconsistency test suggested no significant difference between the results of direct and indirect comparisons.Conclusion:Acupuncture methods might be an effective alternative treatment for herpes zoster and fire-acupuncture plus electro-acupuncture might be considered the best option among the included treatments.However,the results of this study need to be interpreted with caution,because there may still be a problem of small sample size of some studies and interventions.Future research,with a standard methodology and design,requires large-scale trials to validate the effect identified in this meta-analysis.
