目的探讨术前心率变异性(heart rate variability,HRV)对老年患者输尿管镜钬激光碎石术(uteroscopic holmium laser lithotripsy,UHLL)术后疼痛的预测价值。方法选取2021—2022年解放军总医院第六医学中心行UHLL的老年输尿管结石患者40...目的探讨术前心率变异性(heart rate variability,HRV)对老年患者输尿管镜钬激光碎石术(uteroscopic holmium laser lithotripsy,UHLL)术后疼痛的预测价值。方法选取2021—2022年解放军总医院第六医学中心行UHLL的老年输尿管结石患者40例,依据视觉模拟评分(visual analogue scale,VAS)分为有痛组(VAS>3分,17例)和无痛组(VAS≤3分,23例),采用多因素logistic回归方程分析老年患者UHLL术后疼痛的影响因素,采用ROC曲线分析影响因素对老年患者UHLL术后疼痛的预测价值。结果40例患者中,男34例、女6例,年龄65~77岁,平均(63.8±4.1)岁。多因素分析结果显示,正常心跳间距的标准差(the standard deviation of N-N,SDNN)、正常心跳间距平均值的标准差(the standard deviation of the average value of N-NS,SDANN)、相邻正常R-R间期差值的均方根值(the root mean square of successive R-R interval differences,RMSSD)和高频功率(high frequency,HF)越低,低频功率(low frequency,LF)越高的老年患者,UHLL术后发生疼痛的风险越高(P<0.05),SDNN、SDANN预测术后疼痛的ROC曲线的AUC分别为0.819(95%CI:0.669~0.930,P<0.05)、0.803(95%CI:0.669~0.936,P<0.05)。SDNN和SDANN的cut-off值分别为96.5和82.5,灵敏度分别为0.762和0.810,特异性分别为0.791和0.803。结论HRV相关参数SDNN、SDANN、RMSSD、HF,LF是老年患者UHLL术后疼痛的影响因素,其中SDNN和SDANN对术后疼痛有一定预测价值,是提高老年患者UHLL术后疼痛识别率的有效指标。展开更多
We have studied the adsorption of elemental S on the surfaces of NiW alloy substrates where elementary sulfur was used as sulfur source.Compared with those previous investigations which used H2S as the sulfur source a...We have studied the adsorption of elemental S on the surfaces of NiW alloy substrates where elementary sulfur was used as sulfur source.Compared with those previous investigations which used H2S as the sulfur source and operated in an ultra-high vacuum chamber,we used elemental sulfur as the sulfur source which does not need an ultra-high vacuum chamber but Ar-H protection atmosphere in the process of sulfuration.After sulfuration,epitaxial LZO buffer layers were deposited on these substrates directly.The samples were investigated by means of AFM,XPS,SEM and XRD in this study.The results show that after sulfuration,S forms a c(2×2)structure at a coverage of 0.5 ML,in agreement with previous results,representing the effectiveness of elemental sulfur during the sulfuration process.The c(2×2)-S superstructure on the surface of the NiW substrates has optimized the La2Zr2O7(LZO)buffer layer texture.展开更多
文摘目的探讨术前心率变异性(heart rate variability,HRV)对老年患者输尿管镜钬激光碎石术(uteroscopic holmium laser lithotripsy,UHLL)术后疼痛的预测价值。方法选取2021—2022年解放军总医院第六医学中心行UHLL的老年输尿管结石患者40例,依据视觉模拟评分(visual analogue scale,VAS)分为有痛组(VAS>3分,17例)和无痛组(VAS≤3分,23例),采用多因素logistic回归方程分析老年患者UHLL术后疼痛的影响因素,采用ROC曲线分析影响因素对老年患者UHLL术后疼痛的预测价值。结果40例患者中,男34例、女6例,年龄65~77岁,平均(63.8±4.1)岁。多因素分析结果显示,正常心跳间距的标准差(the standard deviation of N-N,SDNN)、正常心跳间距平均值的标准差(the standard deviation of the average value of N-NS,SDANN)、相邻正常R-R间期差值的均方根值(the root mean square of successive R-R interval differences,RMSSD)和高频功率(high frequency,HF)越低,低频功率(low frequency,LF)越高的老年患者,UHLL术后发生疼痛的风险越高(P<0.05),SDNN、SDANN预测术后疼痛的ROC曲线的AUC分别为0.819(95%CI:0.669~0.930,P<0.05)、0.803(95%CI:0.669~0.936,P<0.05)。SDNN和SDANN的cut-off值分别为96.5和82.5,灵敏度分别为0.762和0.810,特异性分别为0.791和0.803。结论HRV相关参数SDNN、SDANN、RMSSD、HF,LF是老年患者UHLL术后疼痛的影响因素,其中SDNN和SDANN对术后疼痛有一定预测价值,是提高老年患者UHLL术后疼痛识别率的有效指标。
基金Supported by the Fundamental Research Funds for the Central Universities(N090602008)The National High Technology Research and Development Program of China(2009AA032401)Shaanxi Provincial Natural Science Foundation(2009JM6002)
文摘We have studied the adsorption of elemental S on the surfaces of NiW alloy substrates where elementary sulfur was used as sulfur source.Compared with those previous investigations which used H2S as the sulfur source and operated in an ultra-high vacuum chamber,we used elemental sulfur as the sulfur source which does not need an ultra-high vacuum chamber but Ar-H protection atmosphere in the process of sulfuration.After sulfuration,epitaxial LZO buffer layers were deposited on these substrates directly.The samples were investigated by means of AFM,XPS,SEM and XRD in this study.The results show that after sulfuration,S forms a c(2×2)structure at a coverage of 0.5 ML,in agreement with previous results,representing the effectiveness of elemental sulfur during the sulfuration process.The c(2×2)-S superstructure on the surface of the NiW substrates has optimized the La2Zr2O7(LZO)buffer layer texture.
