Background:This study aimed to illustrate the prevalence of CHD by screening children in extremely high-altitudeareas(over 4000 m to even 5000 m above sea level)and explore an aid model for early diagnosis and treatme...Background:This study aimed to illustrate the prevalence of CHD by screening children in extremely high-altitudeareas(over 4000 m to even 5000 m above sea level)and explore an aid model for early diagnosis and treatmentfor the Tibetan population.Methods:A total of 2242 students from different schools in Ngamring County,Xigaze City,Tibet from September 2019 to September 2020 were selected for screening.The students were examinedthrough the inquiry of their current medical history and family history,cardiac auscultation and a physicalexamination,in order to screen out the suspected cases of CHD,and then the suspected cases were confirmed bycardiac color ultrasound examinations.After that,positive patients were be transferred to Shandong Province forfree treatment.Results:The prevalence of CHD among children in Ngamring County was 3.70%(83 cases),which is the highest incidence rate ever reported.The most common type of CHD was patent ductus arteriosus(PDA),accounting for 55.42%of the total number of cases screened,followed by atrial septal defect(ASD)andventricular septal defect(VSD),accounting for 28.92%and 12.05%,respectively.The prevalence of CHD in childrenat high altitude was significantly higher than that in children at low altitude.The children with CHD weretransferred to Shandong Province for surgery,the operations were successful and their recoveries went well.Conclusions:The results show that high altitude is closely related to the prevalence of CHD,and the incidencein Ngamring County is much higher than that in previous reports.展开更多
Recently,multiple helicenes have attracted enormous attention due to their exceptionally distorted conjugated architectures,appealing optical properties and unique spatial stacking patterns.The electronic and optical ...Recently,multiple helicenes have attracted enormous attention due to their exceptionally distorted conjugated architectures,appealing optical properties and unique spatial stacking patterns.The electronic and optical properties of multiple helicenes could be modulated by heteroatom doping.Herein,the first triple aza[6]helicene was reported by an intramolecular oxidation reaction,which exhibited highly distorted propeller-like geometry revealed by single crystal X-ray diffraction analysis.In comparison to the reported triple oxa[6]helicene,the triple aza[6]helicene demonstrated increased quantum yield(5.5%),and chiroptical properties with a|gabs|value of 0.012 and a|glum|value of 3.0×10^(-3).Furthermore,the stability and chiroptical properties of the triple aza[6]helicene could be enhanced by N-alkylation.展开更多
文摘Background:This study aimed to illustrate the prevalence of CHD by screening children in extremely high-altitudeareas(over 4000 m to even 5000 m above sea level)and explore an aid model for early diagnosis and treatmentfor the Tibetan population.Methods:A total of 2242 students from different schools in Ngamring County,Xigaze City,Tibet from September 2019 to September 2020 were selected for screening.The students were examinedthrough the inquiry of their current medical history and family history,cardiac auscultation and a physicalexamination,in order to screen out the suspected cases of CHD,and then the suspected cases were confirmed bycardiac color ultrasound examinations.After that,positive patients were be transferred to Shandong Province forfree treatment.Results:The prevalence of CHD among children in Ngamring County was 3.70%(83 cases),which is the highest incidence rate ever reported.The most common type of CHD was patent ductus arteriosus(PDA),accounting for 55.42%of the total number of cases screened,followed by atrial septal defect(ASD)andventricular septal defect(VSD),accounting for 28.92%and 12.05%,respectively.The prevalence of CHD in childrenat high altitude was significantly higher than that in children at low altitude.The children with CHD weretransferred to Shandong Province for surgery,the operations were successful and their recoveries went well.Conclusions:The results show that high altitude is closely related to the prevalence of CHD,and the incidencein Ngamring County is much higher than that in previous reports.
文摘Recently,multiple helicenes have attracted enormous attention due to their exceptionally distorted conjugated architectures,appealing optical properties and unique spatial stacking patterns.The electronic and optical properties of multiple helicenes could be modulated by heteroatom doping.Herein,the first triple aza[6]helicene was reported by an intramolecular oxidation reaction,which exhibited highly distorted propeller-like geometry revealed by single crystal X-ray diffraction analysis.In comparison to the reported triple oxa[6]helicene,the triple aza[6]helicene demonstrated increased quantum yield(5.5%),and chiroptical properties with a|gabs|value of 0.012 and a|glum|value of 3.0×10^(-3).Furthermore,the stability and chiroptical properties of the triple aza[6]helicene could be enhanced by N-alkylation.
