BACKGROUND Diabetic foot ulcers(DFUs)present a significant healthcare challenge attributable to their high rates of disability and the limitations of applied traditional nursing approaches.Effective management is crit...BACKGROUND Diabetic foot ulcers(DFUs)present a significant healthcare challenge attributable to their high rates of disability and the limitations of applied traditional nursing approaches.Effective management is critical for uneventful health outcomes.AIM To investigate the effects of multidisciplinary team(MDT)nursing interventions and blood glucose control on the negative emotions and satisfaction of DFUhealing patients.METHODS This retrospective cohort study included 115 patients with DFUs,divided into MDT and blood glucose control intervention group(n=60)and standard care control group(n=55).The comparison factors were wound area,new granulation tissue coverage area,wound healing rate,2-hour postprandial blood glucose level,fasting plasma glucose level,Hamilton Anxiety Scale score,Hamilton Depression Scale score,and nursing satisfaction.RESULTS After 4 weeks,the average wound area reduced from 22.04±6.48 cm^(2)to 11.96±3.63 cm^(2)(P<0.05).New granulation tissue coverage area reached 52.85±18.39 cm^(2) for the intervention group and 28.39±9.94 cm^(2)(P<0.05)in the control group,respectively.The healing rate was significantly higher in the intervention group than in the control group(91.7%vs 76.4%,P<0.05).Fasting plasma glucose decreased more sharply in the intervention group(from 8.36±0.98 mmol/L to 6.91±1.23 mmol/L)than in the control group(8.41±1.05 mmol/L to 7.81±1.27 mmol/L),with the intervention group maintaining significantly lower levels(P<0.05).The intervention group demonstrated a significantly greater reduction in 2-hour postprandial blood glucose levels(11.35±2.67 mmol/L to 7.52±1.38 mmol/L)compared to the control group(11.61±3.01 mmol/L to 8.72±1.63 mmol/L;P<0.05).Hamilton Anxiety Scale and Hamilton Depression Scale scores were significantly lower in the intervention group(P<0.05).Patient satisfaction with nursing was 93.33%and 74.55%in the intervention and control groups,respectively(P<0.05).CONCLUSION MDT combined with blood glucose control enhanced healing rates and positively influenced emotional well-being and satisfaction among patients.This strategy holds potential for application in clinical practice.展开更多
Surface tension-induced shrinkage of heterogeneously bonded interfaces is a key factor in limiting the performance of nanostructures.Herein,we demonstrate a laser-induced thermo-compression bonding technology to suppr...Surface tension-induced shrinkage of heterogeneously bonded interfaces is a key factor in limiting the performance of nanostructures.Herein,we demonstrate a laser-induced thermo-compression bonding technology to suppress surface tension-induced shrinkage of Cu-Au bonded interface.A focused laser beam is used to apply localized heating and scattering force to the exposed Cu nanowire.The laser-induced scattering force and the heating can be adjusted by regulating the exposure intensity.When the ratio of scattering forces to the gravity of the exposed nanowire reaches 3.6×10^(3),the molten Cu nanowire is compressed into flattened shape rather than shrinking into nanosphere by the surface tension.As a result,the Cu-Au bonding interface is broadened fourfold by the scattering force,leading to a reduction in contact resistance of approximately 56%.This noncontact thermo-compression bonding technology provides significant possibilities for the interconnect packaging and integration of nanodevices.展开更多
In northern China,light and temperature are major limiting factors for plant growth,particularly during seed production and seedling establishment.While previous studies suggested a possible role for the MYB97 gene in...In northern China,light and temperature are major limiting factors for plant growth,particularly during seed production and seedling establishment.While previous studies suggested a possible role for the MYB97 gene in cold-stress,confirmation through documented evidence was lacking.In this study,we transformed the MYB97 gene from Iris laevigata into tobacco,and discovered that the gene boosted photosynthesis,photoprotection and resilience to cold.The transgenic tobacco seeds exhibited enhanced germination and accelerated seedling growth.Moreover,these plants had decreased levels of MDA(Malondialdehyde)and relative conductance,coupled with elevated concentrations of proline and soluble sugars.This response was accompanied by heightened activity of antioxidant enzymes during periods of cold stress(4 and−2℃).Exposure to low temperatures(0–15℃)also reduced heights but accentuated primary root growth in transgenic tobacco plants.Additionally,tobacco leaves showed an increased growth along with higher chlorophyll levels,net photosynthetic rates,stomatal conductance,transpiration rates and non-photochemical quenching coefficient.This study shows that IlMYB97(The MYB97 genes in I.laevigata)improves cold-resistance,and enhances photosynthesis and photoprotective ability,and thus overall growth and development.These findings would offer the genetic resources to further study cold resistance and photosynthesis.展开更多
基金Supported by the Zhejiang Provincial Science and Technology Plan for Traditional Chinese Medicine,No.2025ZL594Municipal-Level Science and Technology Plan Project of Zhejiang Province,No.2023ZD039.
文摘BACKGROUND Diabetic foot ulcers(DFUs)present a significant healthcare challenge attributable to their high rates of disability and the limitations of applied traditional nursing approaches.Effective management is critical for uneventful health outcomes.AIM To investigate the effects of multidisciplinary team(MDT)nursing interventions and blood glucose control on the negative emotions and satisfaction of DFUhealing patients.METHODS This retrospective cohort study included 115 patients with DFUs,divided into MDT and blood glucose control intervention group(n=60)and standard care control group(n=55).The comparison factors were wound area,new granulation tissue coverage area,wound healing rate,2-hour postprandial blood glucose level,fasting plasma glucose level,Hamilton Anxiety Scale score,Hamilton Depression Scale score,and nursing satisfaction.RESULTS After 4 weeks,the average wound area reduced from 22.04±6.48 cm^(2)to 11.96±3.63 cm^(2)(P<0.05).New granulation tissue coverage area reached 52.85±18.39 cm^(2) for the intervention group and 28.39±9.94 cm^(2)(P<0.05)in the control group,respectively.The healing rate was significantly higher in the intervention group than in the control group(91.7%vs 76.4%,P<0.05).Fasting plasma glucose decreased more sharply in the intervention group(from 8.36±0.98 mmol/L to 6.91±1.23 mmol/L)than in the control group(8.41±1.05 mmol/L to 7.81±1.27 mmol/L),with the intervention group maintaining significantly lower levels(P<0.05).The intervention group demonstrated a significantly greater reduction in 2-hour postprandial blood glucose levels(11.35±2.67 mmol/L to 7.52±1.38 mmol/L)compared to the control group(11.61±3.01 mmol/L to 8.72±1.63 mmol/L;P<0.05).Hamilton Anxiety Scale and Hamilton Depression Scale scores were significantly lower in the intervention group(P<0.05).Patient satisfaction with nursing was 93.33%and 74.55%in the intervention and control groups,respectively(P<0.05).CONCLUSION MDT combined with blood glucose control enhanced healing rates and positively influenced emotional well-being and satisfaction among patients.This strategy holds potential for application in clinical practice.
基金supported by the National Natural Science Foundation of China(Nos.52305612 and U20A6004)Open Fund of Hubei Key Laboratory of Electronic Manufacturing and Packaging Integration(Wuhan University)(NO.EMPI2023015).
文摘Surface tension-induced shrinkage of heterogeneously bonded interfaces is a key factor in limiting the performance of nanostructures.Herein,we demonstrate a laser-induced thermo-compression bonding technology to suppress surface tension-induced shrinkage of Cu-Au bonded interface.A focused laser beam is used to apply localized heating and scattering force to the exposed Cu nanowire.The laser-induced scattering force and the heating can be adjusted by regulating the exposure intensity.When the ratio of scattering forces to the gravity of the exposed nanowire reaches 3.6×10^(3),the molten Cu nanowire is compressed into flattened shape rather than shrinking into nanosphere by the surface tension.As a result,the Cu-Au bonding interface is broadened fourfold by the scattering force,leading to a reduction in contact resistance of approximately 56%.This noncontact thermo-compression bonding technology provides significant possibilities for the interconnect packaging and integration of nanodevices.
基金supported by the Science and Technology Basic Resources Investigation Program of China(2019FY100500)the Fun-damental Research Funds for the Central Universities(2572023CT18)the Natural Fund Project of Heilongjiang Province(LH 2020C 044).
文摘In northern China,light and temperature are major limiting factors for plant growth,particularly during seed production and seedling establishment.While previous studies suggested a possible role for the MYB97 gene in cold-stress,confirmation through documented evidence was lacking.In this study,we transformed the MYB97 gene from Iris laevigata into tobacco,and discovered that the gene boosted photosynthesis,photoprotection and resilience to cold.The transgenic tobacco seeds exhibited enhanced germination and accelerated seedling growth.Moreover,these plants had decreased levels of MDA(Malondialdehyde)and relative conductance,coupled with elevated concentrations of proline and soluble sugars.This response was accompanied by heightened activity of antioxidant enzymes during periods of cold stress(4 and−2℃).Exposure to low temperatures(0–15℃)also reduced heights but accentuated primary root growth in transgenic tobacco plants.Additionally,tobacco leaves showed an increased growth along with higher chlorophyll levels,net photosynthetic rates,stomatal conductance,transpiration rates and non-photochemical quenching coefficient.This study shows that IlMYB97(The MYB97 genes in I.laevigata)improves cold-resistance,and enhances photosynthesis and photoprotective ability,and thus overall growth and development.These findings would offer the genetic resources to further study cold resistance and photosynthesis.
