目的探讨心脏磁共振(cardiac magnetic resonance,CMR)评价心肌梗死后室壁瘤对左心室功能的影响,并探究其对患者长期预后的指导作用。方法选取自2018年1月~2019年9月南京大学医学院附属鼓楼医院心肌梗死合并室壁瘤形成的行CMR的68例患...目的探讨心脏磁共振(cardiac magnetic resonance,CMR)评价心肌梗死后室壁瘤对左心室功能的影响,并探究其对患者长期预后的指导作用。方法选取自2018年1月~2019年9月南京大学医学院附属鼓楼医院心肌梗死合并室壁瘤形成的行CMR的68例患者为观察对象,根据美国纽约心脏病学会分级(NYHA)将35例NYHAⅠ~Ⅱ级患者分为A组,33例NYHAⅢ~Ⅳ级患者为B组。对两组患者进行CMR检查,比较心功能参数及室壁瘤参数,分析室壁瘤对患者左心室心功能的影响。结果两组患者左心室收缩和舒张功能均不同程度减低,差异有统计学意义。CMR较心脏超声比较,敏感性和特异性更高,CMR较心脏彩超检测的左心室射血分数在两组间差异更加明显。在CMR检测数据中,与A组比较,B组患者的左心室舒张末容积、左心室收缩末容积、室壁瘤瘤体基底部横径、容积均显著升高,左心室射血分数、心输出量、峰值射血率均明显降低(P<0.05),室壁瘤瘤体高度有增高趋势,但差异无统计学意义。左心室射血分数与室壁瘤瘤体基底部横径及室壁瘤瘤体容积均呈负相关。左心室舒张末容积、左心室收缩末容积和室壁瘤容积呈正相关。结论心肌梗死室壁瘤形成后左心室收缩和舒张功能均与室壁瘤范围相关,CMR可精准测量心功能参数及室壁瘤范围,能准确评估心功能,对患者预后和临床治疗具有重要指导价值。展开更多
Numerical simulation of groundwater in karst areas has long been restricted by the difficulty of generalizing the hydrogeological conditions of reservoirs and of determining the relevant parameters due to the anisotro...Numerical simulation of groundwater in karst areas has long been restricted by the difficulty of generalizing the hydrogeological conditions of reservoirs and of determining the relevant parameters due to the anisotropy and discontinuity of the karst water-bearing media in these areas. In this study, we used the Guang'an Longtan Coal mine in Sichuan as an example, and generalized the complex hydrogeological conditions in the reservoir area. A finite element numerical flow model was used to simulate current and future scenarios of roadway gushing at the bottom of the coal mine at pile number 1 + 700 m. The results show that the roadway section corresponding to valleys has a gushing quantity of 4323.8–4551.25 m^3/d before impoundment. Modeled water inflow after impoundment increased to 1.6 times the water inflow before impoundment, which threatens the impoundment as well as the roadway's normal operation. Therefore, roadway processing measures are needed to guarantee the safety of the impoundment and of the mining operation.展开更多
文摘目的探讨心脏磁共振(cardiac magnetic resonance,CMR)评价心肌梗死后室壁瘤对左心室功能的影响,并探究其对患者长期预后的指导作用。方法选取自2018年1月~2019年9月南京大学医学院附属鼓楼医院心肌梗死合并室壁瘤形成的行CMR的68例患者为观察对象,根据美国纽约心脏病学会分级(NYHA)将35例NYHAⅠ~Ⅱ级患者分为A组,33例NYHAⅢ~Ⅳ级患者为B组。对两组患者进行CMR检查,比较心功能参数及室壁瘤参数,分析室壁瘤对患者左心室心功能的影响。结果两组患者左心室收缩和舒张功能均不同程度减低,差异有统计学意义。CMR较心脏超声比较,敏感性和特异性更高,CMR较心脏彩超检测的左心室射血分数在两组间差异更加明显。在CMR检测数据中,与A组比较,B组患者的左心室舒张末容积、左心室收缩末容积、室壁瘤瘤体基底部横径、容积均显著升高,左心室射血分数、心输出量、峰值射血率均明显降低(P<0.05),室壁瘤瘤体高度有增高趋势,但差异无统计学意义。左心室射血分数与室壁瘤瘤体基底部横径及室壁瘤瘤体容积均呈负相关。左心室舒张末容积、左心室收缩末容积和室壁瘤容积呈正相关。结论心肌梗死室壁瘤形成后左心室收缩和舒张功能均与室壁瘤范围相关,CMR可精准测量心功能参数及室壁瘤范围,能准确评估心功能,对患者预后和临床治疗具有重要指导价值。
基金supported by the National Natural Science Foundation of China (41272377)
文摘Numerical simulation of groundwater in karst areas has long been restricted by the difficulty of generalizing the hydrogeological conditions of reservoirs and of determining the relevant parameters due to the anisotropy and discontinuity of the karst water-bearing media in these areas. In this study, we used the Guang'an Longtan Coal mine in Sichuan as an example, and generalized the complex hydrogeological conditions in the reservoir area. A finite element numerical flow model was used to simulate current and future scenarios of roadway gushing at the bottom of the coal mine at pile number 1 + 700 m. The results show that the roadway section corresponding to valleys has a gushing quantity of 4323.8–4551.25 m^3/d before impoundment. Modeled water inflow after impoundment increased to 1.6 times the water inflow before impoundment, which threatens the impoundment as well as the roadway's normal operation. Therefore, roadway processing measures are needed to guarantee the safety of the impoundment and of the mining operation.
