Dear Editor,Breath analysis is a promising diagnostic approach for various conditions[1,2].It is based on the identification of volatile organic compounds(VOCs)emitted in the breath,which creates a unique volatolomic ...Dear Editor,Breath analysis is a promising diagnostic approach for various conditions[1,2].It is based on the identification of volatile organic compounds(VOCs)emitted in the breath,which creates a unique volatolomic signature[3].Owing to their characteristics,VOCs can be measured non-intrusively from the breath or other body sources[3,4].Several studies have shown the diagnostic potential for a variety of conditions based on VOC analysis[5-9].Malignant diseases,where early detection is crucial,are the main focus of VOC analysis,with lung cancer(LC)and gastric cancer(GC)being the most studied.LC and GC together were responsible for approximately 2.5 million deaths globally in 2018[10].The aim of VOC analysis of the breath using sensors is to identify a“VOC-print”comprising the total abundances and ratios of the compounds in the breath,giving an overall unique chemical pattern[11].展开更多
基金This study received partial funding from the Horizon 2020 Information Communication Technology(ICT)Program under the breath Volatile Organic compound analysis for GAstric cancer Screening(VOGAS)project(grant agreement no.824986)In addition,the project was partially funded by Jiangsu Sunshine Haick Co.,which provided the breath sampling kits and systems.
文摘Dear Editor,Breath analysis is a promising diagnostic approach for various conditions[1,2].It is based on the identification of volatile organic compounds(VOCs)emitted in the breath,which creates a unique volatolomic signature[3].Owing to their characteristics,VOCs can be measured non-intrusively from the breath or other body sources[3,4].Several studies have shown the diagnostic potential for a variety of conditions based on VOC analysis[5-9].Malignant diseases,where early detection is crucial,are the main focus of VOC analysis,with lung cancer(LC)and gastric cancer(GC)being the most studied.LC and GC together were responsible for approximately 2.5 million deaths globally in 2018[10].The aim of VOC analysis of the breath using sensors is to identify a“VOC-print”comprising the total abundances and ratios of the compounds in the breath,giving an overall unique chemical pattern[11].
