[目的]基于文献计量学探究植物固土领域的研究热点和趋势,为该领域研究现状和发展提供参考和指导。[方法]以中国知网(CNKI)和Web of Science(WoS)数据库为数据来源,利用VOSviewer和CiteSpace相结合方式对1993-2023年植物固土领域发文量...[目的]基于文献计量学探究植物固土领域的研究热点和趋势,为该领域研究现状和发展提供参考和指导。[方法]以中国知网(CNKI)和Web of Science(WoS)数据库为数据来源,利用VOSviewer和CiteSpace相结合方式对1993-2023年植物固土领域发文量、国家、机构、研究人员、关键词进行可视化分析。[结果](1)发文量呈现出缓慢增长后持续性快速增长,发文量CNKI近年趋于稳定而WoS爆发增长。(2)中国是研究植物固土产出最多的国家,但研究质量仍有提升空间,北京林业大学、云南农业大学、内蒙古农业大学这3家机构是植物固土领域的主要机构,合作发文呈现团队机构内合作紧密,但机构外合作较为缺乏。(3)植物固土领域围绕着边坡稳定性、根系力学、根土抗剪方面开展研究,突现词分析可知,WoS以水土流失预测、黄土高原、机械性能,CNKI以根系形态、消落带、力学特性、自修复以及生态修复为近3 a研究热点。[结论]中国是该领域研究产出最多的国家,但其研究质量和团队机构间的合作交流仍有提升空间,研究植物类型多为草本植物且研究周期较短,未来应加深对其他植物类型和周期的研究,同时研究的生态脆弱地区目前仍旧单一,今后仍需扩大研究区的范围。展开更多
Based on quantum mechanical representation and operator theory,this paper restates the two new convolutions of fractional Fourier transform(FrFT)by making full use of the conversion relationship between two mutual con...Based on quantum mechanical representation and operator theory,this paper restates the two new convolutions of fractional Fourier transform(FrFT)by making full use of the conversion relationship between two mutual conjugates:coordinate representation and momentum representation.This paper gives full play to the efficiency of Dirac notation and proves the convolutions of fractional Fourier transform from the perspective of quantum optics,a field that has been developing rapidly.These two new convolution methods have potential value in signal processing.展开更多
Rapeseed(Brassica napus L.)is one of the main oil crops in the world,and increasing its yield is of great significance for ensuring the safety of edible oil.Presently,improving rapeseed plant architecture is an effect...Rapeseed(Brassica napus L.)is one of the main oil crops in the world,and increasing its yield is of great significance for ensuring the safety of edible oil.Presently,improving rapeseed plant architecture is an effective way to increase rapeseed yield with higher planting density.However,the regulatory mechanism of rapeseed plant architecture is poorly understood.In this study,a dwarf rapeseed mutant dwarf08(df08)is obtained by ethyl methane sulfonate(EMS)-mutagenesis.The decrease in plant height of df08 is mainly caused by the reduction in main inflorescence length and first effective branch height and controlled by a single semi-dominant gene.The hybrid plants(F1)show a semi-dwarf phenotype.Through map-based cloning and transgenic assay,we confirm that the nonsynonymous single nucleotide variant(SNV)(C to T)in BnaC03.BIN2,which is homologous with Arabidopsis(Arabidopsis thaliana)BIN2,is responsible for the dwarfism of df08.BnaC03.BIN2 interacts with BnaBZR1/BES1 and involves in brassinosteroids(BRs)signal transduction.Proline to Leucine substitution in 284(P284L)enhances the protein stability of BnaC03.bin2-D,disrupts BRs signal transduction and affects the expression of genes regulating cell division,leading to dwarfism of df08.This study provides a new insight for the mechanism of rapeseed plant height regulation and creates an elite germplasm that can be used for genetic improvement of rapeseed architecture.展开更多
We study radiative transfer in participating binary stochastic mixtures in two dimensions(2D)by developing an accurate and efficient simulation tool.For two different sets of physical parameters,2D benchmark results a...We study radiative transfer in participating binary stochastic mixtures in two dimensions(2D)by developing an accurate and efficient simulation tool.For two different sets of physical parameters,2D benchmark results are presented,and it is found that the influence of the stochastic mixture on radiative transfer is clearly parameter-dependent.Our results confirm that previous multidimensional results obtained in different studies are basically consistent,which is interpreted in terms of the relationship between the photon mean free path l_(p)and the system size L.Nonlinear effects,including those due to scattering and radiation-material coupling,are also discussed.To further understand the particle size effect,we employ a dimensionless parameter l_(p)/L,from which a critical particle size can be derived.On the basis of further 2D simulations,we find that an inhomogeneous mix is obtained for l_(p)/L>0.1.Furthermore,2D material temperature distributions reveal that self-shielding and particle-particle shielding of radiation occur,and are enhanced when l_(p)/L is increased.Our work is expected to provide benchmark results to verify proposed homogenized models and/or other codes for stochastic radiative transfer in realistic physical scenarios.展开更多
This article was originally published online on 30 August 2024.Due to a production error,as originally published the author list was not in its intended order.All online versions of this article were corrected on 9 Se...This article was originally published online on 30 August 2024.Due to a production error,as originally published the author list was not in its intended order.All online versions of this article were corrected on 9 September 2024 and it appears correctly in print.AIP Publishing apologizes for this error.展开更多
Ta-based materials have gained significant interest for bioimplantable scaffolds because of their appropriate mechanical characteristics and biocompatibility.To overcome the serious limitation of bioinertness,there ha...Ta-based materials have gained significant interest for bioimplantable scaffolds because of their appropriate mechanical characteristics and biocompatibility.To overcome the serious limitation of bioinertness,there have been many efforts to enhance the bioactivity and osseointegration of Ta-based scaffolds through morphostructural and surface modifications.As scaffolds are implantable devices,sufficient bioactivity is needed to trigger the cellular functions required for tissue engineering.Consequently,a combination of materials and bioscience is needed to develop efficient Ta-based scaffolds,although reviews of this interdisciplinary field remain limited.This review aims to provide an overview of the main strategies to enhance the bioactivity of Ta-based scaffolds,describing the basic mechanisms and research methods of osseointegration,and the approaches to enhance bioactivity and osseointegration.These approaches are divided into three main sections:(i)alteration of the micromorphology,(ii)customization of the scaffold structure,and(iii)functionalization modifications(through alloying or the addition of surface coatings).Also provided are recent advances regarding biocompatibility assessment in vitro,osseointegration properties in vivo,and clinical trial results.展开更多
Background:Exercise is a promising nonpharmacological therapy for cognitive dysfunction,but it is unclear which type of exercise is most effective.The objective of this study was to compare and rank the effectiveness ...Background:Exercise is a promising nonpharmacological therapy for cognitive dysfunction,but it is unclear which type of exercise is most effective.The objective of this study was to compare and rank the effectiveness of various exercise interventions on cognitive function in patients with mild cognitive impairment(MCI)or dementia and to examine the effects of exercise on the symptoms relevant to cognitive impairment.Methods:We searched PubMed,Web of Science,Embase,Cochrane Central Register of Controlled Trials,SPORTDiscus,and PsycInfo through September 2019 and included randomized controlled trials that examined the effectiveness of exercise interventions in patients with MCI or dementia.Primary outcomes included global cognition,executive cognition,and memory cognition.Secondary outcomes included activities of daily living,neuropsychiatric symptoms,and quality of life.Pairwise analyses and network meta-analyses were performed using a random effects model.Results:A total of 73 articles from 71 trials with 5606 participants were included.All types of exercise were effective in increasing or maintaining global cognition,and resistance exercise had the highest probability of being the most effective intervention in slowing the decrease in global cognition(standard mean difference(SMD)=1.05,95%confidence interval(95%CI):0.56-1.54),executive function(SMD=0.85,95%CI:0.21-1.49),and memory function(SMD=0.32,95%CI:0.01-0.63)in patients with cognitive dysfunction.Subgroup analyses for patients with MCI revealed different effects,and multicomponent exercise was most likely to be the optimal exercise therapy for preventing the decline of global cognition(SMD=0.99,95%CI:0.44-1.54)and executive function(SMD=0.72,95%CI:0.06-1.38).However,only resistance exercise showed significant effects on memory function for patients with MCI(SMD=0.35,95%CI:0.01-0.69).Exercise interventions also showed various effects on the secondary outcomes.Conclusion:Resistance exercise has the highest probability of being the optimal exercise type for slowing cognitive declin e in patients withcognitive dysfunction,especially in patients with dementia.Multicomponent exercise tends to be most effective in protecting global cognition and executive function in patients with MCI.展开更多
Cold-inducible RNA-binding protein（CIRP）, a key regulatory protein, could be facilitated by mild hypothermia in the brain, heart and liver. This study observed the effects of mild hypothermia at 31 ± 0.5℃ on t...Cold-inducible RNA-binding protein（CIRP）, a key regulatory protein, could be facilitated by mild hypothermia in the brain, heart and liver. This study observed the effects of mild hypothermia at 31 ± 0.5℃ on traumatic brain injury in rats. Results demonstrated that mild hypothermia suppressed apoptosis in the cortex, hippocampus and hypothalamus, facilitated CIRP m RNA and protein expression in these regions, especially in the hypothalamus. The anti-apoptotic effect of mild hypothermia disappeared after CIRP silencing. There was no correlation between mitogen-activated extracellular signal-regulated kinase activation and CIRP silencing. CIRP silencing inhibited extracellular signal-regulated kinase-1/2 activation. These indicate that CIRP inhibits apoptosis by affecting extracellular signal-regulated kinase-1/2 activation, and exerts a neuroprotective effect during mild hypothermia for traumatic brain injury.展开更多
In this study,complete tetracycline(TTC)and above 50%of total organic carbon(TOC)were removed by Fe S/PS after 30 min under optimized conditions.Although free radicals and high-valent iron ions were identified to gene...In this study,complete tetracycline(TTC)and above 50%of total organic carbon(TOC)were removed by Fe S/PS after 30 min under optimized conditions.Although free radicals and high-valent iron ions were identified to generate in the process,the apparent similarity between intermediate products of Fe S/PS,Fe/PS,and UV/PS systems demonstrated that the degradation of TTC was due to sulfate radicals(SO_(4)·^(-))and hydroxyl radicals(·OH).Based on the reaction between free radicals and organic matter,we speculated that TTC in the Fe S/PS system was decomposed and mineralized by dehydration,dehydrogenation,hydroxyl addition,demethylation,substitution,E-transfer,and ring-opening.Furthermore,a new understanding of Fe S-mediated PS activation based on stoichiometry and kinetic analysis showed that there were both homogeneous and heterogeneous reactions that occurred in the entire progress.However,due to the effect of p H on the dissolution of iron ions,the homogeneous reaction became the principal process with iron ions concentration exceeding 1.35 mg/L.This work provides a theoretical basis for the study of the degradation of TTC-containing wastewater by the iron-based advanced oxidation process.展开更多
To ameliorate the electrochemical hydrogen storage properties of RE-Mg-Ni-Mn-based AB2-type electrode alloys,La element was partially substituted by Ce,and La1-xCexMgNi3.5Mn0.5(x=0,0.1,0.2,0.3,0.4)alloys were fabricat...To ameliorate the electrochemical hydrogen storage properties of RE-Mg-Ni-Mn-based AB2-type electrode alloys,La element was partially substituted by Ce,and La1-xCexMgNi3.5Mn0.5(x=0,0.1,0.2,0.3,0.4)alloys were fabricated by casting and melt spinning.The effects of Ce content on structures and electrochemical hydrogen storage properties of prepared alloys were studied in detail.Results show that the experimental alloys consist of LaMgNi4 and LaNi5 phases.The variation of Ce content,instead of changing phase composition,results in an obvious phase abundance change in the alloys,namely the amount of LaMgNi4 and LaNi5 phases,respectively,increases and decreases with Ce content growing.Moreover,the partial substitution of Ce for La leads to that the lattice keeps constant,cell volumes clearly decreases and the alloy grains are markedly refined.The electrochemical measurements reveal that the as-cast and as-spun alloys obtain the maximum discharge capacities at the first cycling without any activation needed.With Ce content increasing,the discharge capacity of as-cast alloys visibly decreases.By contrast,the as-spun alloys have the maximum discharge capacity value.The substitution of Ce for La dramatically promotes the cycle stability.Moreover,the electrochemical kinetic performances of as-cast and asspun alloys first increase and then decrease with Ce content increasing.展开更多
The RE-Mg-Ni-Mn-based AB2-type La（1-x）CexMgNi（3.5）Mn（0.5）（ x = 0- 0. 4） alloys were prepared by spinning treatment. For obtaining the optimum performance,the effects of Ce content and spinning rate on the hydr...The RE-Mg-Ni-Mn-based AB2-type La（1-x）CexMgNi（3.5）Mn（0.5）（ x = 0- 0. 4） alloys were prepared by spinning treatment. For obtaining the optimum performance,the effects of Ce content and spinning rate on the hydrogen storage performance of the alloys were studied systematically. The results show that the variations of the spinning rate and Ce content result in noteworthy changes of the phase content without altering phase composition of the alloys. Specifically,the LaMgNi4 phase increases and LaNi5 phase decreases when increasing the spinning rate and Ce content. Furthermore,the crystalline grains of Cecontaining alloys prepared by spinning treatment are remarkably refined. The alloys own superior electrochemical performance. All alloys reach the optimal discharge capacity at the initial cycle. Increasing Ce content and spinning rate lead the discharge capacity and electrochemical kinetics rise to an optimal value and then start to reduce. Meanwhile,the electrochemical cycle stability is also improved,which is ascribed to the great enhancement of anti-pulverization and anti-corrosion abilities resulting from the spinning treatment and the substitution of Ce for La.展开更多
Health monitoring data or the data about infectious diseases such as COVID-19 may need to be constantly updated and dynamically released,but they may contain user's sensitive information.Thus,how to preserve the u...Health monitoring data or the data about infectious diseases such as COVID-19 may need to be constantly updated and dynamically released,but they may contain user's sensitive information.Thus,how to preserve the user's privacy before their release is critically important yet challenging.Differential Privacy(DP)is well-known to provide effective privacy protection,and thus the dynamic DP preserving data release was designed to publish a histogram to meet DP guarantee.Unfortunately,this scheme may result in high cumulative errors and lower the data availability.To address this problem,in this paper,we apply Jensen-Shannon(JS)divergence to design the OPTICS(Ordering Points To Identify The Clustering Structure)scheme.It uses JS divergence to measure the difference between the updated data set at the current release time and private data set at the previous release time.By comparing the difference with a threshold,only when the difference is greater than the threshold,can we apply OPTICS to publish DP protected data sets.Our experimental results show that the absolute errors and average relative errors are significantly lower than those existing works.展开更多
A new chromatographic purification of single-walled carbon nanotubes using high-speed countercurrent chromatography is reported. The purification was accomplished on the basis of experiment that dispersed the single-w...A new chromatographic purification of single-walled carbon nanotubes using high-speed countercurrent chromatography is reported. The purification was accomplished on the basis of experiment that dispersed the single-walled carbon nanotubes with sodium dodecyl sulfate, and the result mixture was separated using the two phase system composed of n-butanol/water = 1/1 （v/v）. The sizes of SWNTs separated were observed by scanning electron microscopy. The results demonstrated that the high-speed countercurrent chromatography possessed a good efficency for purification of single-walled carbon nanotubes.展开更多
comitant esotropia(AACE).METHODS:A retrospective cohort study was conducted by analyzing 83 patients(case group)with AACE who underwent strabismus correction surgery from January 1,2021 to June 30,2022.Totally 73 outp...comitant esotropia(AACE).METHODS:A retrospective cohort study was conducted by analyzing 83 patients(case group)with AACE who underwent strabismus correction surgery from January 1,2021 to June 30,2022.Totally 73 outpatient volunteers were recruited during the same period as the normal control group.The case group’s binocular vision time,near and distance esotropia angle,and near stereo vision function were recorded,and the age,gender,refractive status,and best-corrected visual acuity(BCVA)of both groups were analyzed.Additionally,multiple logistic regression analysis was conducted using an eye usage condition questionnaire to determine the independent risk factors for AACE.RESULTS:In the case group,61 patients(73.49%)had myopia,with a mean equivalent spherical power(SE)of-3.35±3.31 D(range:+2.75 to-10.62 D)of the right eye and-2.87±3.35 D(range:+2.75 to-11.12 D)of the left eye.The average duration of diplopia in the case group was 29.83±35.72mo,of which 80 patients(96.39%)were primarily with distance diplopia.The near and distance esotropia angle after wearing glasses were 52.36±20.95 prism degree(PD)and 56.71±19.54 PD,respectively,and there was no statistically significant difference between the two(t=1.38,P=0.169).The incidence of improper glasses wearing and unhealthy eye habits in the case group was significantly higher than those in the control group(P<0.05).Close-up work without glasses[β=2.30,odds ratio(OR)=10,95%confidence interval(CI)2.35-42.51,P=0.002]and near work in supine position(β=1.80,OR=6.02,95%CI 3.29-11.02,P<0.001)were independent risk factors for AACE.CONCLUSION:Patients with AACE mainly present with distance diplopia,and there is a high degree of variation in myopia.Near work without wearing glasses and in supine position are independent risk factors for AACE.展开更多
文摘[目的]基于文献计量学探究植物固土领域的研究热点和趋势,为该领域研究现状和发展提供参考和指导。[方法]以中国知网(CNKI)和Web of Science(WoS)数据库为数据来源,利用VOSviewer和CiteSpace相结合方式对1993-2023年植物固土领域发文量、国家、机构、研究人员、关键词进行可视化分析。[结果](1)发文量呈现出缓慢增长后持续性快速增长,发文量CNKI近年趋于稳定而WoS爆发增长。(2)中国是研究植物固土产出最多的国家,但研究质量仍有提升空间,北京林业大学、云南农业大学、内蒙古农业大学这3家机构是植物固土领域的主要机构,合作发文呈现团队机构内合作紧密,但机构外合作较为缺乏。(3)植物固土领域围绕着边坡稳定性、根系力学、根土抗剪方面开展研究,突现词分析可知,WoS以水土流失预测、黄土高原、机械性能,CNKI以根系形态、消落带、力学特性、自修复以及生态修复为近3 a研究热点。[结论]中国是该领域研究产出最多的国家,但其研究质量和团队机构间的合作交流仍有提升空间,研究植物类型多为草本植物且研究周期较短,未来应加深对其他植物类型和周期的研究,同时研究的生态脆弱地区目前仍旧单一,今后仍需扩大研究区的范围。
基金National Natural Science Foundation of China(Grant Number:11304126)College Students' Innovation Training Program(Grant Number:202110299696X)。
文摘Based on quantum mechanical representation and operator theory,this paper restates the two new convolutions of fractional Fourier transform(FrFT)by making full use of the conversion relationship between two mutual conjugates:coordinate representation and momentum representation.This paper gives full play to the efficiency of Dirac notation and proves the convolutions of fractional Fourier transform from the perspective of quantum optics,a field that has been developing rapidly.These two new convolution methods have potential value in signal processing.
基金supported by the National Key Research and Development Program of China(2022YFD1200401)the National Natural Science Foundation of China(U22A20477,32172095)the Central Public-interest Scientific Institution Basal Research Fund(Y2022QC21).
文摘Rapeseed(Brassica napus L.)is one of the main oil crops in the world,and increasing its yield is of great significance for ensuring the safety of edible oil.Presently,improving rapeseed plant architecture is an effective way to increase rapeseed yield with higher planting density.However,the regulatory mechanism of rapeseed plant architecture is poorly understood.In this study,a dwarf rapeseed mutant dwarf08(df08)is obtained by ethyl methane sulfonate(EMS)-mutagenesis.The decrease in plant height of df08 is mainly caused by the reduction in main inflorescence length and first effective branch height and controlled by a single semi-dominant gene.The hybrid plants(F1)show a semi-dwarf phenotype.Through map-based cloning and transgenic assay,we confirm that the nonsynonymous single nucleotide variant(SNV)(C to T)in BnaC03.BIN2,which is homologous with Arabidopsis(Arabidopsis thaliana)BIN2,is responsible for the dwarfism of df08.BnaC03.BIN2 interacts with BnaBZR1/BES1 and involves in brassinosteroids(BRs)signal transduction.Proline to Leucine substitution in 284(P284L)enhances the protein stability of BnaC03.bin2-D,disrupts BRs signal transduction and affects the expression of genes regulating cell division,leading to dwarfism of df08.This study provides a new insight for the mechanism of rapeseed plant height regulation and creates an elite germplasm that can be used for genetic improvement of rapeseed architecture.
基金financial support by the National Natural Science Foundation of China(Grant No.12374259)funded by the National Natural Science Foundation of China under Grant No.12375235。
文摘We study radiative transfer in participating binary stochastic mixtures in two dimensions(2D)by developing an accurate and efficient simulation tool.For two different sets of physical parameters,2D benchmark results are presented,and it is found that the influence of the stochastic mixture on radiative transfer is clearly parameter-dependent.Our results confirm that previous multidimensional results obtained in different studies are basically consistent,which is interpreted in terms of the relationship between the photon mean free path l_(p)and the system size L.Nonlinear effects,including those due to scattering and radiation-material coupling,are also discussed.To further understand the particle size effect,we employ a dimensionless parameter l_(p)/L,from which a critical particle size can be derived.On the basis of further 2D simulations,we find that an inhomogeneous mix is obtained for l_(p)/L>0.1.Furthermore,2D material temperature distributions reveal that self-shielding and particle-particle shielding of radiation occur,and are enhanced when l_(p)/L is increased.Our work is expected to provide benchmark results to verify proposed homogenized models and/or other codes for stochastic radiative transfer in realistic physical scenarios.
文摘This article was originally published online on 30 August 2024.Due to a production error,as originally published the author list was not in its intended order.All online versions of this article were corrected on 9 September 2024 and it appears correctly in print.AIP Publishing apologizes for this error.
基金Financially Natural Science Foundation of Shandong Province(No.ZR2023ME181)。
文摘Ta-based materials have gained significant interest for bioimplantable scaffolds because of their appropriate mechanical characteristics and biocompatibility.To overcome the serious limitation of bioinertness,there have been many efforts to enhance the bioactivity and osseointegration of Ta-based scaffolds through morphostructural and surface modifications.As scaffolds are implantable devices,sufficient bioactivity is needed to trigger the cellular functions required for tissue engineering.Consequently,a combination of materials and bioscience is needed to develop efficient Ta-based scaffolds,although reviews of this interdisciplinary field remain limited.This review aims to provide an overview of the main strategies to enhance the bioactivity of Ta-based scaffolds,describing the basic mechanisms and research methods of osseointegration,and the approaches to enhance bioactivity and osseointegration.These approaches are divided into three main sections:(i)alteration of the micromorphology,(ii)customization of the scaffold structure,and(iii)functionalization modifications(through alloying or the addition of surface coatings).Also provided are recent advances regarding biocompatibility assessment in vitro,osseointegration properties in vivo,and clinical trial results.
文摘目的:腹膜假黏液瘤(pseudomyxoma peritonei,PMP)是一种罕见的临床综合征,细胞减灭术(cytoreductive surgery,CRS)联合腹腔热灌注化疗(hyperthermic intraperitoneal chemotherapy,HIPEC)因其良好的治疗效果已经成为各中心公认的标准治疗方案,航天中心医院从2008年开始致力于PMP患者诊治工作,2016年开始将全腹膜切除应用于临床,本研究通过对既往资料进行收集整理,对PMP治疗经验进行总结。方法:回顾分析2008年1月到2019年1月航天中心医院腹膜假黏液瘤中心收治并接受手术治疗的PMP患者临床资料及随访结果。对所有患者的手术方式、根治程度及并发症发生情况等临床资料进行搜集整理,并通过随访结果对相关因素进行生存分析,了解CRS+HIPEC在PMP治疗中的临床价值,同时对腹膜切除技术治疗效果进行评价。结果:共纳入854例患者,平均年龄50岁,中位改良腹膜肿瘤指数(peritoneal cancer index,PCI)为29,其中25.5%的患者接受了根治性手术切除,细胞减灭程度(completeness of cytoreduction,CC)达到0或1。总体并发症发生率为21.7%,围术期死亡率为1.1%。自2016年引进腹膜切除技术后,本中心达CC-0/1的比例由14.3%升至36.5%,且并发症发生率显著下降(16.8%vs.28.8%,P<0.001)。总体而言,CC-0/1的患者5年和10年生存率分别为77%、64.3%,显著优于CC-2/3患者的45.8%、39.4%。在未达根治的患者中,CC-2和CC-3患者10年生存率也存在明显差异(45.5%vs.34.5%,P=0.006)。对总体生存进行分析,改良腹膜肿瘤指数、手术方式、术中是否行热灌注治疗、病理级别、CA125水平均为影响术后生存的独立危险因素。结论:细胞减灭术+腹腔热灌注化疗治疗腹膜假黏液瘤安全有效,腹膜切除技术可显著提高根治程度并降低并发症风险;对于无法达到根治切除的患者,最大限度的减瘤亦可延长远期生存。
基金financial support from the National Natural Science Foundation of Chinafunded by the National Natural Science Foundation of China(81871854)。
文摘Background:Exercise is a promising nonpharmacological therapy for cognitive dysfunction,but it is unclear which type of exercise is most effective.The objective of this study was to compare and rank the effectiveness of various exercise interventions on cognitive function in patients with mild cognitive impairment(MCI)or dementia and to examine the effects of exercise on the symptoms relevant to cognitive impairment.Methods:We searched PubMed,Web of Science,Embase,Cochrane Central Register of Controlled Trials,SPORTDiscus,and PsycInfo through September 2019 and included randomized controlled trials that examined the effectiveness of exercise interventions in patients with MCI or dementia.Primary outcomes included global cognition,executive cognition,and memory cognition.Secondary outcomes included activities of daily living,neuropsychiatric symptoms,and quality of life.Pairwise analyses and network meta-analyses were performed using a random effects model.Results:A total of 73 articles from 71 trials with 5606 participants were included.All types of exercise were effective in increasing or maintaining global cognition,and resistance exercise had the highest probability of being the most effective intervention in slowing the decrease in global cognition(standard mean difference(SMD)=1.05,95%confidence interval(95%CI):0.56-1.54),executive function(SMD=0.85,95%CI:0.21-1.49),and memory function(SMD=0.32,95%CI:0.01-0.63)in patients with cognitive dysfunction.Subgroup analyses for patients with MCI revealed different effects,and multicomponent exercise was most likely to be the optimal exercise therapy for preventing the decline of global cognition(SMD=0.99,95%CI:0.44-1.54)and executive function(SMD=0.72,95%CI:0.06-1.38).However,only resistance exercise showed significant effects on memory function for patients with MCI(SMD=0.35,95%CI:0.01-0.69).Exercise interventions also showed various effects on the secondary outcomes.Conclusion:Resistance exercise has the highest probability of being the optimal exercise type for slowing cognitive declin e in patients withcognitive dysfunction,especially in patients with dementia.Multicomponent exercise tends to be most effective in protecting global cognition and executive function in patients with MCI.
基金supported by the National Natural Science Foundation of China,No.81303091
文摘Cold-inducible RNA-binding protein（CIRP）, a key regulatory protein, could be facilitated by mild hypothermia in the brain, heart and liver. This study observed the effects of mild hypothermia at 31 ± 0.5℃ on traumatic brain injury in rats. Results demonstrated that mild hypothermia suppressed apoptosis in the cortex, hippocampus and hypothalamus, facilitated CIRP m RNA and protein expression in these regions, especially in the hypothalamus. The anti-apoptotic effect of mild hypothermia disappeared after CIRP silencing. There was no correlation between mitogen-activated extracellular signal-regulated kinase activation and CIRP silencing. CIRP silencing inhibited extracellular signal-regulated kinase-1/2 activation. These indicate that CIRP inhibits apoptosis by affecting extracellular signal-regulated kinase-1/2 activation, and exerts a neuroprotective effect during mild hypothermia for traumatic brain injury.
基金supported by the National Natural Science Foundation of China(No.21876130)Natural Science Foundation of Shanghai(No.18ZR1440800)。
文摘In this study,complete tetracycline(TTC)and above 50%of total organic carbon(TOC)were removed by Fe S/PS after 30 min under optimized conditions.Although free radicals and high-valent iron ions were identified to generate in the process,the apparent similarity between intermediate products of Fe S/PS,Fe/PS,and UV/PS systems demonstrated that the degradation of TTC was due to sulfate radicals(SO_(4)·^(-))and hydroxyl radicals(·OH).Based on the reaction between free radicals and organic matter,we speculated that TTC in the Fe S/PS system was decomposed and mineralized by dehydration,dehydrogenation,hydroxyl addition,demethylation,substitution,E-transfer,and ring-opening.Furthermore,a new understanding of Fe S-mediated PS activation based on stoichiometry and kinetic analysis showed that there were both homogeneous and heterogeneous reactions that occurred in the entire progress.However,due to the effect of p H on the dissolution of iron ions,the homogeneous reaction became the principal process with iron ions concentration exceeding 1.35 mg/L.This work provides a theoretical basis for the study of the degradation of TTC-containing wastewater by the iron-based advanced oxidation process.
基金financially supported by the National Natural Science Foundation of China(Nos.51161015,51371094 and 51471054)the Natural Science Foundation of Inner Mongolia,China(No.2015MS0558)
文摘To ameliorate the electrochemical hydrogen storage properties of RE-Mg-Ni-Mn-based AB2-type electrode alloys,La element was partially substituted by Ce,and La1-xCexMgNi3.5Mn0.5(x=0,0.1,0.2,0.3,0.4)alloys were fabricated by casting and melt spinning.The effects of Ce content on structures and electrochemical hydrogen storage properties of prepared alloys were studied in detail.Results show that the experimental alloys consist of LaMgNi4 and LaNi5 phases.The variation of Ce content,instead of changing phase composition,results in an obvious phase abundance change in the alloys,namely the amount of LaMgNi4 and LaNi5 phases,respectively,increases and decreases with Ce content growing.Moreover,the partial substitution of Ce for La leads to that the lattice keeps constant,cell volumes clearly decreases and the alloy grains are markedly refined.The electrochemical measurements reveal that the as-cast and as-spun alloys obtain the maximum discharge capacities at the first cycling without any activation needed.With Ce content increasing,the discharge capacity of as-cast alloys visibly decreases.By contrast,the as-spun alloys have the maximum discharge capacity value.The substitution of Ce for La dramatically promotes the cycle stability.Moreover,the electrochemical kinetic performances of as-cast and asspun alloys first increase and then decrease with Ce content increasing.
基金financially sponsored by National Natural Science Foundation of China(51371094 and 51471054)
文摘The RE-Mg-Ni-Mn-based AB2-type La（1-x）CexMgNi（3.5）Mn（0.5）（ x = 0- 0. 4） alloys were prepared by spinning treatment. For obtaining the optimum performance,the effects of Ce content and spinning rate on the hydrogen storage performance of the alloys were studied systematically. The results show that the variations of the spinning rate and Ce content result in noteworthy changes of the phase content without altering phase composition of the alloys. Specifically,the LaMgNi4 phase increases and LaNi5 phase decreases when increasing the spinning rate and Ce content. Furthermore,the crystalline grains of Cecontaining alloys prepared by spinning treatment are remarkably refined. The alloys own superior electrochemical performance. All alloys reach the optimal discharge capacity at the initial cycle. Increasing Ce content and spinning rate lead the discharge capacity and electrochemical kinetics rise to an optimal value and then start to reduce. Meanwhile,the electrochemical cycle stability is also improved,which is ascribed to the great enhancement of anti-pulverization and anti-corrosion abilities resulting from the spinning treatment and the substitution of Ce for La.
基金supported in part by National Natural Science Foundation of China(No.61672106)in part by Natural Science Foundation of Beijing,China(L192023)in part by the project of promoting the Classified Development of Beijing Information Science and Technology University(No.5112211038,5112211039)。
文摘Health monitoring data or the data about infectious diseases such as COVID-19 may need to be constantly updated and dynamically released,but they may contain user's sensitive information.Thus,how to preserve the user's privacy before their release is critically important yet challenging.Differential Privacy(DP)is well-known to provide effective privacy protection,and thus the dynamic DP preserving data release was designed to publish a histogram to meet DP guarantee.Unfortunately,this scheme may result in high cumulative errors and lower the data availability.To address this problem,in this paper,we apply Jensen-Shannon(JS)divergence to design the OPTICS(Ordering Points To Identify The Clustering Structure)scheme.It uses JS divergence to measure the difference between the updated data set at the current release time and private data set at the previous release time.By comparing the difference with a threshold,only when the difference is greater than the threshold,can we apply OPTICS to publish DP protected data sets.Our experimental results show that the absolute errors and average relative errors are significantly lower than those existing works.
基金supported by National Natural Science Foundation (No.20775066)Yunnan Province's Natural Science Foundations of China (Nos.2005E0006Z and 2007B203M).
文摘A new chromatographic purification of single-walled carbon nanotubes using high-speed countercurrent chromatography is reported. The purification was accomplished on the basis of experiment that dispersed the single-walled carbon nanotubes with sodium dodecyl sulfate, and the result mixture was separated using the two phase system composed of n-butanol/water = 1/1 （v/v）. The sizes of SWNTs separated were observed by scanning electron microscopy. The results demonstrated that the high-speed countercurrent chromatography possessed a good efficency for purification of single-walled carbon nanotubes.
基金Supported by the Guangxi Health Appropriate Technology Development and Application Project(No.S2021093)the Education and Teaching Reform Project of Guangxi Medical University(No.2021XJGA18)。
文摘comitant esotropia(AACE).METHODS:A retrospective cohort study was conducted by analyzing 83 patients(case group)with AACE who underwent strabismus correction surgery from January 1,2021 to June 30,2022.Totally 73 outpatient volunteers were recruited during the same period as the normal control group.The case group’s binocular vision time,near and distance esotropia angle,and near stereo vision function were recorded,and the age,gender,refractive status,and best-corrected visual acuity(BCVA)of both groups were analyzed.Additionally,multiple logistic regression analysis was conducted using an eye usage condition questionnaire to determine the independent risk factors for AACE.RESULTS:In the case group,61 patients(73.49%)had myopia,with a mean equivalent spherical power(SE)of-3.35±3.31 D(range:+2.75 to-10.62 D)of the right eye and-2.87±3.35 D(range:+2.75 to-11.12 D)of the left eye.The average duration of diplopia in the case group was 29.83±35.72mo,of which 80 patients(96.39%)were primarily with distance diplopia.The near and distance esotropia angle after wearing glasses were 52.36±20.95 prism degree(PD)and 56.71±19.54 PD,respectively,and there was no statistically significant difference between the two(t=1.38,P=0.169).The incidence of improper glasses wearing and unhealthy eye habits in the case group was significantly higher than those in the control group(P<0.05).Close-up work without glasses[β=2.30,odds ratio(OR)=10,95%confidence interval(CI)2.35-42.51,P=0.002]and near work in supine position(β=1.80,OR=6.02,95%CI 3.29-11.02,P<0.001)were independent risk factors for AACE.CONCLUSION:Patients with AACE mainly present with distance diplopia,and there is a high degree of variation in myopia.Near work without wearing glasses and in supine position are independent risk factors for AACE.
