We put forward a new design of a compact beam transport system for intense laser-driven proton therapy,where instead of using conventional pulsed solenoids,our design relies on a helical coil irradiated by a nanosecon...We put forward a new design of a compact beam transport system for intense laser-driven proton therapy,where instead of using conventional pulsed solenoids,our design relies on a helical coil irradiated by a nanosecond laser pulse to generate strong magnetic fields for focusing protons.A pair of dipole magnets and apertures are employed to further filter protons with large divergences and low energies.Our numerical studies combine particle-in-cell simulations for laser-plasma interaction to generate high-energy monoenergetic proton beams,finite element analysis for evaluating the magnetic field distribution inside the coil,and MonteCarlo simulations for beam transport and energy deposition.Our results show that with this design,a spread-out Bragg peak in a range of several centimeters to a deep-seated tumor with a dose of approximately 16.5 cGy and fluctuation around 2% can be achieved.The instantaneous dose rate reaches up to 10^(9)Gy/s,holding the potential for future FLASH radiotherapy research.展开更多
Neutron production driven by intense lasers utilizing inverse kinematic reactions is explored self-consistently by a combination of particle-in-cell simulations for laser-driven ion acceleration and Monte Carlo nuclea...Neutron production driven by intense lasers utilizing inverse kinematic reactions is explored self-consistently by a combination of particle-in-cell simulations for laser-driven ion acceleration and Monte Carlo nuclear reaction simulations for neutron production.It is proposed that laser-driven light-sail acceleration from ultrathin lithium foils can provide an energetic lithium-ion beam as the projectile bombarding a light hydrocarbon target with sufficiently high flux for the inverse p(^(7)Li,n)reaction to be efficiently achieved.Three-dimensional self-consistent simulations show that a forward-directed pulsed neutron source with ultrashort pulse duration 3 ns,small divergence angle 260,and extremely high peak flux 3×10^(14)n/(cm^(2)·s)can be produced by petawatt lasers at intensities of 10^(21)W/cm^(2).These results indicate that a laser-driven neutron source based on inverse kinematics has promise as a novel compact pulsed neutron generator for practical applications,since the it can operate in a safe and repetitive way with almost no undesirable radiation.展开更多
基金supported by the National Key R&D Program of China(Nos.2022YFA1603200 and 2022YFA1603201)National Natural Science Foundation of China(Nos.12135001,11921006,12475243 and 11825502)+1 种基金Strategic Priority Research Program of CAS(No.XDA25050900)support from the National Natural Science Funds for Distinguished Young Scholar(No.11825502)。
文摘We put forward a new design of a compact beam transport system for intense laser-driven proton therapy,where instead of using conventional pulsed solenoids,our design relies on a helical coil irradiated by a nanosecond laser pulse to generate strong magnetic fields for focusing protons.A pair of dipole magnets and apertures are employed to further filter protons with large divergences and low energies.Our numerical studies combine particle-in-cell simulations for laser-plasma interaction to generate high-energy monoenergetic proton beams,finite element analysis for evaluating the magnetic field distribution inside the coil,and MonteCarlo simulations for beam transport and energy deposition.Our results show that with this design,a spread-out Bragg peak in a range of several centimeters to a deep-seated tumor with a dose of approximately 16.5 cGy and fluctuation around 2% can be achieved.The instantaneous dose rate reaches up to 10^(9)Gy/s,holding the potential for future FLASH radiotherapy research.
基金supported by the National Key R&D Program of China(Grant Nos.2022YFA1603200 and 2022YFA1603201)the National Natural Science Foundation of China(Grant Nos.12135001,11825502,and 11921006)+1 种基金the Strategic Priority Research Program of CAS(Grant No.XDA25050900)the National Natural Science Funds for Distinguished Young Scholars(Grant No.11825502)。
文摘Neutron production driven by intense lasers utilizing inverse kinematic reactions is explored self-consistently by a combination of particle-in-cell simulations for laser-driven ion acceleration and Monte Carlo nuclear reaction simulations for neutron production.It is proposed that laser-driven light-sail acceleration from ultrathin lithium foils can provide an energetic lithium-ion beam as the projectile bombarding a light hydrocarbon target with sufficiently high flux for the inverse p(^(7)Li,n)reaction to be efficiently achieved.Three-dimensional self-consistent simulations show that a forward-directed pulsed neutron source with ultrashort pulse duration 3 ns,small divergence angle 260,and extremely high peak flux 3×10^(14)n/(cm^(2)·s)can be produced by petawatt lasers at intensities of 10^(21)W/cm^(2).These results indicate that a laser-driven neutron source based on inverse kinematics has promise as a novel compact pulsed neutron generator for practical applications,since the it can operate in a safe and repetitive way with almost no undesirable radiation.
基金supported by the National Natural Science Foundation of China(41901061,32100356)the High-level Talents Funds of Qingdao Agricultural University,China(663-1119008,663-1118015).
基金financially supported by the Funds for Creative Research Groups of China(51921001)the 111 Project(BP0719004)+1 种基金the Program for Changjiang Scholars,Innovative Research Team in University of China(IRT_14R05)the National Natural Science Foundation of China(11790293 and 51871016)。
