In this study, the influences of accumulated mileage （deterioration） and technological changes （emission standards） on emission factors （EFs） of regulated pollutants （CO, HC, and NOx） from gasoline passenger v...In this study, the influences of accumulated mileage （deterioration） and technological changes （emission standards） on emission factors （EFs） of regulated pollutants （CO, HC, and NOx） from gasoline passenger vehicles were investigated based on Inspection and Maintenance （I/M） data using the chassis dynamometer method. The accumulated mileage of passenger vehicles was significantly linearly correlated with vehicle age. For most cases, the average EFs of CO, HC and NOx were significantly linearly correlated with accumulated mileage, indicating that emission deterioration had a significant impact on pollutant EFs. Implemented emission standards markedly influenced the EFs of regulated pollutants, and EFs markedly decreased with progressing emission standards. The present study also compared EFs of regulated pollutants between this study and the International vehicle emission （IVE） model, and marked differences in EFs were seen with variations in emission standards, vehicle types and accumulated mileage; NOx EFs in this study were higher than in the IVE model. The results provide new insight into estimating regulated pollutant emissions using the IVE model.展开更多
目的探讨糖尿病肾病(DN)患者血清铁蛋白(SF)、C反应蛋白(CRP)与营养状况的相关性。方法选取2019年1月至2022年4月天津市泰达医院收治的158例DN患者作为试验组,依据临床分期分为早期组(临床分期3期,55例)、中期组(临床分期4期,57例)、晚...目的探讨糖尿病肾病(DN)患者血清铁蛋白(SF)、C反应蛋白(CRP)与营养状况的相关性。方法选取2019年1月至2022年4月天津市泰达医院收治的158例DN患者作为试验组,依据临床分期分为早期组(临床分期3期,55例)、中期组(临床分期4期,57例)、晚期组(临床分期5期,46例),另选取同期天津市泰达医院收治的40例未合并肾病的糖尿病患者作为对照组,检测所有研究对象的实验室检查指标[24 h尿蛋白定量(24 h UTP)、血尿素氮(BUN)、血清肌酐(SCr)、甘油三酯(TG)、总胆固醇(TC)、白蛋白(Alb)、血红蛋白(Hb)、SF、CRP]水平并比较;采用Pearson相关性分析SF、CRP与营养状况的相关性。结果试验组24 h UTP、BUN、SCr、TG、TC、SF、CRP水平均高于对照组,Alb、Hb水平均低于对照组,差异有统计学意义(P<0.05)。中、晚期组24 h UTP、BUN、SCr、TG、TC、SF、CRP水平均高于早期组,且晚期组高于中期组,差异有统计学意义(P<0.05)。中、晚期组Alb、Hb水平均低于早期组,且晚期组低于中期组,差异有统计学意义(P<0.05)。Pearson相关性分析显示,SF、CRP与Alb、Hb呈负相关(P<0.05),与TC呈正相关(P<0.05),与TG无关,且SF与CRP呈正相关(P<0.05)。结论DN患者SF、CRP与营养状况具有相关性,临床可通过检测SF、CRP评估DN患者的营养状况,并据此为治疗、预后提供参考。展开更多
OBJECTIVE:To determine the effects of Bushenhuoxue formula(BHF) on interleukin-1 beta(IL-1β),transforming growth factor beta 1(TGF-β1),discoidin domain receptor 2(DDR2) and matrix metalloproteinase-1(MMP-1) levels i...OBJECTIVE:To determine the effects of Bushenhuoxue formula(BHF) on interleukin-1 beta(IL-1β),transforming growth factor beta 1(TGF-β1),discoidin domain receptor 2(DDR2) and matrix metalloproteinase-1(MMP-1) levels in a rat model of osteoarthritis(OA).METHODS:Sprague-Dawley rats were used to establish an OA model and subjected to various treatments over 6 weeks.Rats were treated with BHF,glucosamine sulfate(G5),or starch as a control.Serum levels of IL-1β and MMP-1 and joint fluid levels of IL-1 β were determined by means of ELISAs.We used immunohistochemistry to determine DDR2 levels in knee cartilage.Gene expression levels of MMP-1 in joint synovial tissue were assessed using reverse transcription polymerase chain reaction assays.RESULTS:Serum IL-1β levels were unchanged throughout the study.Levels of IL-1β in joint fluid and MMP-1 in sera from the BHF- and GS-treated groups were significantly reduced.DDR2 levels in knee cartilage were also significantly reduced in the BHF group.Expression of the MMP-1 gene was significantly reduced by BHF treatment.CONCLUSION:BHF might be beneficial in the inhibition and alleviation of local inflammatory responses and cartilage degeneration in OA.展开更多
Heart rate is an important vital characteristic which indicates physical and mental health status.Typically heart rate measurement instruments require direct contact with the skin which is time-consuming and costly.Th...Heart rate is an important vital characteristic which indicates physical and mental health status.Typically heart rate measurement instruments require direct contact with the skin which is time-consuming and costly.Therefore,the study of non-contact heart rate measurement methods is of great importance.Based on the principles of photoelectric volumetric tracing,we use a computer device and camera to capture facial images,accurately detect face regions,and to detect multiple facial images using a multi-target tracking algorithm.Then after the regional segmentation of the facial image,the signal acquisition of the region of interest is further resolved.Finally,frequency detection of the collected Photo-plethysmography(PPG)and Electrocardiography(ECG)signals is completed with peak detection,Fourier analysis,and a Waveletfilter.The experimental results show that the subject’s heart rate can be detected quickly and accurately even when monitoring multiple facial targets simultaneously.展开更多
Phytosterols are a group of steroids alcohols which had been regarded as a functional factor. An unknown compound in phytosterol samples and phytosterol standard samples was detected by HPLC using symmetry C18 column....Phytosterols are a group of steroids alcohols which had been regarded as a functional factor. An unknown compound in phytosterol samples and phytosterol standard samples was detected by HPLC using symmetry C18 column. The quan- tity of the compound was increased with the enrichment of β-sitosterol. After being collected and analyzed by GC-MS and compared with standard diagram from Wiley and Nist standard chart library, it proved to be γ-sitosterol, a 24β epimer of β-sitosterol.展开更多
基金supported by the National Natural Science Foundation of China (No. 21577125)the Social Development Special Fund from Science and Technology Bureau of Hangzhou, China (No. 20110533B09)
文摘In this study, the influences of accumulated mileage （deterioration） and technological changes （emission standards） on emission factors （EFs） of regulated pollutants （CO, HC, and NOx） from gasoline passenger vehicles were investigated based on Inspection and Maintenance （I/M） data using the chassis dynamometer method. The accumulated mileage of passenger vehicles was significantly linearly correlated with vehicle age. For most cases, the average EFs of CO, HC and NOx were significantly linearly correlated with accumulated mileage, indicating that emission deterioration had a significant impact on pollutant EFs. Implemented emission standards markedly influenced the EFs of regulated pollutants, and EFs markedly decreased with progressing emission standards. The present study also compared EFs of regulated pollutants between this study and the International vehicle emission （IVE） model, and marked differences in EFs were seen with variations in emission standards, vehicle types and accumulated mileage; NOx EFs in this study were higher than in the IVE model. The results provide new insight into estimating regulated pollutant emissions using the IVE model.
文摘目的探讨糖尿病肾病(DN)患者血清铁蛋白(SF)、C反应蛋白(CRP)与营养状况的相关性。方法选取2019年1月至2022年4月天津市泰达医院收治的158例DN患者作为试验组,依据临床分期分为早期组(临床分期3期,55例)、中期组(临床分期4期,57例)、晚期组(临床分期5期,46例),另选取同期天津市泰达医院收治的40例未合并肾病的糖尿病患者作为对照组,检测所有研究对象的实验室检查指标[24 h尿蛋白定量(24 h UTP)、血尿素氮(BUN)、血清肌酐(SCr)、甘油三酯(TG)、总胆固醇(TC)、白蛋白(Alb)、血红蛋白(Hb)、SF、CRP]水平并比较;采用Pearson相关性分析SF、CRP与营养状况的相关性。结果试验组24 h UTP、BUN、SCr、TG、TC、SF、CRP水平均高于对照组,Alb、Hb水平均低于对照组,差异有统计学意义(P<0.05)。中、晚期组24 h UTP、BUN、SCr、TG、TC、SF、CRP水平均高于早期组,且晚期组高于中期组,差异有统计学意义(P<0.05)。中、晚期组Alb、Hb水平均低于早期组,且晚期组低于中期组,差异有统计学意义(P<0.05)。Pearson相关性分析显示,SF、CRP与Alb、Hb呈负相关(P<0.05),与TC呈正相关(P<0.05),与TG无关,且SF与CRP呈正相关(P<0.05)。结论DN患者SF、CRP与营养状况具有相关性,临床可通过检测SF、CRP评估DN患者的营养状况,并据此为治疗、预后提供参考。
基金Supported by the Shandong Provincial Department of Education(Mechanism of Bushenhuoxue Formula Protecting Chondrocytes of Osteoarthritis,No.J07YD08)the Shandong Provincial Administration of Traditional Chinese Medicine(Relationship between Bushenhuoxue Formula and the Osteoarthritis Signaling Molecule DDR2,No.2007-027)
文摘OBJECTIVE:To determine the effects of Bushenhuoxue formula(BHF) on interleukin-1 beta(IL-1β),transforming growth factor beta 1(TGF-β1),discoidin domain receptor 2(DDR2) and matrix metalloproteinase-1(MMP-1) levels in a rat model of osteoarthritis(OA).METHODS:Sprague-Dawley rats were used to establish an OA model and subjected to various treatments over 6 weeks.Rats were treated with BHF,glucosamine sulfate(G5),or starch as a control.Serum levels of IL-1β and MMP-1 and joint fluid levels of IL-1 β were determined by means of ELISAs.We used immunohistochemistry to determine DDR2 levels in knee cartilage.Gene expression levels of MMP-1 in joint synovial tissue were assessed using reverse transcription polymerase chain reaction assays.RESULTS:Serum IL-1β levels were unchanged throughout the study.Levels of IL-1β in joint fluid and MMP-1 in sera from the BHF- and GS-treated groups were significantly reduced.DDR2 levels in knee cartilage were also significantly reduced in the BHF group.Expression of the MMP-1 gene was significantly reduced by BHF treatment.CONCLUSION:BHF might be beneficial in the inhibition and alleviation of local inflammatory responses and cartilage degeneration in OA.
基金supported by the National Nature Science Foundation of China(Grant Number:61962010).
文摘Heart rate is an important vital characteristic which indicates physical and mental health status.Typically heart rate measurement instruments require direct contact with the skin which is time-consuming and costly.Therefore,the study of non-contact heart rate measurement methods is of great importance.Based on the principles of photoelectric volumetric tracing,we use a computer device and camera to capture facial images,accurately detect face regions,and to detect multiple facial images using a multi-target tracking algorithm.Then after the regional segmentation of the facial image,the signal acquisition of the region of interest is further resolved.Finally,frequency detection of the collected Photo-plethysmography(PPG)and Electrocardiography(ECG)signals is completed with peak detection,Fourier analysis,and a Waveletfilter.The experimental results show that the subject’s heart rate can be detected quickly and accurately even when monitoring multiple facial targets simultaneously.
文摘Phytosterols are a group of steroids alcohols which had been regarded as a functional factor. An unknown compound in phytosterol samples and phytosterol standard samples was detected by HPLC using symmetry C18 column. The quan- tity of the compound was increased with the enrichment of β-sitosterol. After being collected and analyzed by GC-MS and compared with standard diagram from Wiley and Nist standard chart library, it proved to be γ-sitosterol, a 24β epimer of β-sitosterol.
