“Ruyong(breast abscess)”has a high incidence rate.Traditional Chinese medicine(TCM)diagnosis and treatment of this condition demonstrate significant advantages,including diverse therapeuticmethods,outstanding effica...“Ruyong(breast abscess)”has a high incidence rate.Traditional Chinese medicine(TCM)diagnosis and treatment of this condition demonstrate significant advantages,including diverse therapeuticmethods,outstanding efficacy,and high safety.Based on TCM theory and combining relevant ancient texts and modern research,this paper systematically summarizes the different understandings of“Ruyong(breast abscess)”by physicians throughout history in terms of disease names,etiology,pathogenesis,and treatment.The ancient names for Ruyong(breast abscess)were varied,also referred to as“Duru(stagnation in breast)”or“Naichuang(breast sore)”.Its symptoms are diverse,with the main clinical manifestations being localized redness,swelling,heat,pain,and poor milk discharge in the affected breast.The etiology is primarily attributed to“milk stasis”“liver qi stagnation and stomach heat”and“exposure to external pathogens”.Additionally,this paper summarizes the treatment experiences from ancient and modern medical texts and highlights the complementary effects of internal and external therapies.This study provides a reference for modern clinical understanding and treatment of“Ruyong(breast abscess)”in the hope of further improvement of clinical efficacy.展开更多
Objective A typical brown tumor caused by hyperparathyroidism(HPT) is rare. In this report, we describe our pathological findings along with a review of the literature to enhance understanding of the disease and preve...Objective A typical brown tumor caused by hyperparathyroidism(HPT) is rare. In this report, we describe our pathological findings along with a review of the literature to enhance understanding of the disease and prevent misdiagnosis, as well as to provide evidence for treatment and prognosis.Methods We present a case of brown tumor of the left proximal femur and pelvis in a 57-year-old woman who was admitted to our hospital(Dalian Municipal Central Hospital, Dalian, China). Pelvic computed tomography(CT) showed cystic expansile lesions in the left proximal femur and pelvis. Lung and abdominal CT also revealed multiple lytic lesions in the ribs and lumbar spine. X-ray of the left ulna and radius showed that the middle of the left ulna had a fracture caused by a brown tumor. A bone biopsy from the left proximal femur showed focal distribution of giant cells, with hemorrhage and fibrin hyperplasia. Results The patient underwent internal fixation of the left intertrochanteric fracture, and postoperative bone biopsy showed focal distribution of giant cells with hemorrhage and fibrin hyperplasia. The patient had a parathyroidectomy 5 months after discharge. Two weeks later, the patient developed a fracture in the right femoral neck and pain in the left forearm. X-ray of the left ulna and radius showed that the middle of the left ulna was affected by a pathological fracture caused by a brown tumor. The patient was debilitated and declined surgical treatment. The patient and her family chose discharge.Conclusion Brown tumor of bone, also called osteitis fibrosa cystica, is a rare non-neoplastic lesion that reflects abnormal bone metabolism in patients with HPT. However, with fine needle aspiration cytology in combination with biochemical tests, a correct diagnosis can be reached. The increase in osteoclast activity leads to decalcification and dissolution of bone, and formation of a cystic bone defect with hyperplastic fibrous tissue. This eventually becomes a brown tumor, with deformed and bleeding fibrous tissue. The patient had a typical brown tumor, as well as osteoporosis, anemia, and pathological fractures.展开更多
This work studies the stability and metastability of stationary patterns in a diffusionchemotaxis model without cell proliferation.We first establish the interval of unstable wave modes of the homogeneous steady state...This work studies the stability and metastability of stationary patterns in a diffusionchemotaxis model without cell proliferation.We first establish the interval of unstable wave modes of the homogeneous steady state,and show that the chemotactic flux is the key mechanism for pattern formation.Then,we treat the chemotaxis coefficient as a bifurcation parameter to obtain the asymptotic expressions of steady states.Based on this,we derive the sufficient conditions for the stability of one-step pattern,and prove the metastability of two or more step patterns.All the analytical results are demonstrated by numerical simulations.展开更多
For conformal Hardy-Littlewood-Sobolev(HLS)inequalities[22]and reversed conformal HLS inequalities[8]on S^(n),a new proof is given for the attainability of their sharp constants.Classical methods used in[22]and[8]depe...For conformal Hardy-Littlewood-Sobolev(HLS)inequalities[22]and reversed conformal HLS inequalities[8]on S^(n),a new proof is given for the attainability of their sharp constants.Classical methods used in[22]and[8]depends on rearrangement inequalities.Here,we use the subcritical approach to construct the extremal sequence and circumvent the blow-up phenomenon by renormalization method.The merit of the method is that it does not rely on rearrangement inequalities.展开更多
基金supported by 2024 Henan Provincial Special Research Project on Traditional Chinese Medicine(2024ZY2158)Henan Provincial Key Discipline Construction Project of Traditional Chinese Medicine{Yuwei Traditional Chinese Medicine Science and Education[2024]No.1}+1 种基金Key Disciplines of History and Literature of Chinese Medicine in Henan University of Chinese Medicine for the Year 2025{Henan Traditional Chinese Medicine Office[2025]No.13}National Chinese Medicine Advantage Specialty Construction Project{Chinese Traditional Chinese Medicine Political Letter(2024)No.90}.
文摘“Ruyong(breast abscess)”has a high incidence rate.Traditional Chinese medicine(TCM)diagnosis and treatment of this condition demonstrate significant advantages,including diverse therapeuticmethods,outstanding efficacy,and high safety.Based on TCM theory and combining relevant ancient texts and modern research,this paper systematically summarizes the different understandings of“Ruyong(breast abscess)”by physicians throughout history in terms of disease names,etiology,pathogenesis,and treatment.The ancient names for Ruyong(breast abscess)were varied,also referred to as“Duru(stagnation in breast)”or“Naichuang(breast sore)”.Its symptoms are diverse,with the main clinical manifestations being localized redness,swelling,heat,pain,and poor milk discharge in the affected breast.The etiology is primarily attributed to“milk stasis”“liver qi stagnation and stomach heat”and“exposure to external pathogens”.Additionally,this paper summarizes the treatment experiences from ancient and modern medical texts and highlights the complementary effects of internal and external therapies.This study provides a reference for modern clinical understanding and treatment of“Ruyong(breast abscess)”in the hope of further improvement of clinical efficacy.
文摘Objective A typical brown tumor caused by hyperparathyroidism(HPT) is rare. In this report, we describe our pathological findings along with a review of the literature to enhance understanding of the disease and prevent misdiagnosis, as well as to provide evidence for treatment and prognosis.Methods We present a case of brown tumor of the left proximal femur and pelvis in a 57-year-old woman who was admitted to our hospital(Dalian Municipal Central Hospital, Dalian, China). Pelvic computed tomography(CT) showed cystic expansile lesions in the left proximal femur and pelvis. Lung and abdominal CT also revealed multiple lytic lesions in the ribs and lumbar spine. X-ray of the left ulna and radius showed that the middle of the left ulna had a fracture caused by a brown tumor. A bone biopsy from the left proximal femur showed focal distribution of giant cells, with hemorrhage and fibrin hyperplasia. Results The patient underwent internal fixation of the left intertrochanteric fracture, and postoperative bone biopsy showed focal distribution of giant cells with hemorrhage and fibrin hyperplasia. The patient had a parathyroidectomy 5 months after discharge. Two weeks later, the patient developed a fracture in the right femoral neck and pain in the left forearm. X-ray of the left ulna and radius showed that the middle of the left ulna was affected by a pathological fracture caused by a brown tumor. The patient was debilitated and declined surgical treatment. The patient and her family chose discharge.Conclusion Brown tumor of bone, also called osteitis fibrosa cystica, is a rare non-neoplastic lesion that reflects abnormal bone metabolism in patients with HPT. However, with fine needle aspiration cytology in combination with biochemical tests, a correct diagnosis can be reached. The increase in osteoclast activity leads to decalcification and dissolution of bone, and formation of a cystic bone defect with hyperplastic fibrous tissue. This eventually becomes a brown tumor, with deformed and bleeding fibrous tissue. The patient had a typical brown tumor, as well as osteoporosis, anemia, and pathological fractures.
基金Manjun Ma was supported by the National Natural Science Foundation of China(Nos.12071434 and 11671359).
文摘This work studies the stability and metastability of stationary patterns in a diffusionchemotaxis model without cell proliferation.We first establish the interval of unstable wave modes of the homogeneous steady state,and show that the chemotactic flux is the key mechanism for pattern formation.Then,we treat the chemotaxis coefficient as a bifurcation parameter to obtain the asymptotic expressions of steady states.Based on this,we derive the sufficient conditions for the stability of one-step pattern,and prove the metastability of two or more step patterns.All the analytical results are demonstrated by numerical simulations.
基金supported by the National Natural Science Foundation of China(Grant No.12071269)Natural Science Foundation of Zhejiang Province(Grant No.LY18A010013).
文摘For conformal Hardy-Littlewood-Sobolev(HLS)inequalities[22]and reversed conformal HLS inequalities[8]on S^(n),a new proof is given for the attainability of their sharp constants.Classical methods used in[22]and[8]depends on rearrangement inequalities.Here,we use the subcritical approach to construct the extremal sequence and circumvent the blow-up phenomenon by renormalization method.The merit of the method is that it does not rely on rearrangement inequalities.
