Dietary parboiled rice(PR)has a low risk of disease,but little is known about the contribution of PR to the prevention of hyperlipidemia.The potential role and underlying mechanisms of PR in hyperlipidemia were evalua...Dietary parboiled rice(PR)has a low risk of disease,but little is known about the contribution of PR to the prevention of hyperlipidemia.The potential role and underlying mechanisms of PR in hyperlipidemia were evaluated in this study.Male C57BL/6J mice were fed with a normal diet,high-fat diet(HFD)containing refined rice(HFDRR)or PR(HFDPR).It was found that PR intervention improved lipid accumulation in mice.Transcriptomic data analysis revealed that 27 genes were up-regulated(mostly involved in lipid breakdown)and 86 genes were down-regulated(mostly involved in inflammatory responses)in the HFDPR group compared to the HFDRR group.And 15 differentially expressed genes(DEGs)were validated by quantitative real-time PCR(RT-qPCR),while protein interaction network showed that protein tyrosine phosphatase receptor type C(PTPRC)has a central role.The gut microbiota of mice was also altered after different dietary treatments,with higher ratio of Firmicutes and Bacteroidetes,increased abundances of Ruminococcaceae,Lachnospiraceae,Christensenellaceae,Porphyromonadaceae,Rikenellaceae and Prevotellaceae,and decreased abundances of Lactobacillaceae,Peptostreptococcaceae,Erysipelotrichaceae and Actinobacteria in the HFDRR group.In addition,it was observed that PPAR signaling pathway may act as a bridge between DEGs and differential gut microbiota.These results suggested that PR can prevent hyperlipidemia by modulating liver genes and gut microbiota.展开更多
Childhood maltreatment,as a typical early adverse environment,is known to have a negative impact on one’s life satisfaction.Mindfulness,on the other hand,may serve as a protective factor.This study explored the media...Childhood maltreatment,as a typical early adverse environment,is known to have a negative impact on one’s life satisfaction.Mindfulness,on the other hand,may serve as a protective factor.This study explored the mediating role of mindfulness and its related variables–positive thoughts,psychological resilience and self-esteem.In order to testify the mechanism,we administered Childhood Trauma Questionnaire(CTQ),Satisfaction with Life Scale(SWLS),Mindful Attention Awareness Scale(MAAS),Connor–Davidson Resilience Scale(CD-RISC)and Rosenberg Self-Esteem Scale(RSES)to a non-clinical sample of Chinese university students(N=1021).The results indicated that positive thoughts did not mediate the relationship between childhood maltreatment and life satisfaction,but self-esteem(β=−0.194,95%CI=[−0.090,−0.040])and psychological resilience(β=−0.063,95%CI=[−0.059,−0.020])mediated the relationship,as well as the“mindfulness-selfesteem”(β=−0.061,95%CI=[−0.287,−0.126])and“mindfulness-psychological resilience”(β=−0.035,95%CI=[−0.115,−0.034]).The results of this study were helpful to understand the relationship between childhood maltreatment and life satisfaction and provided a theoretical basis for the development of mindfulness intervention programs from the perspective of positive psychology.展开更多
Fathers play an important role in adolescents’development,which is significant for their development and influences their mental health,including feeling of loneliness.However,the effects and mechanisms of father-lov...Fathers play an important role in adolescents’development,which is significant for their development and influences their mental health,including feeling of loneliness.However,the effects and mechanisms of father-love absence on individual loneliness are not clear.Based on the social functionalist theory and the social needs theory,this study examines the influence of individual fatherlove absence on loneliness and its underlying mechanisms.A questionnaire survey was administered to 319 junior high school students and 1,476 high school students.The results showed that adolescents with father-love absence had higher levels of loneliness,and that father-love absence affected loneliness levels through mediating pathways of individual gratitude,peer relationships,and gratitude to peer relationships.This study not only confirms the negative effects of father-love absence on adolescents’loneliness,but also explains the mediate roles of individual gratitude and peer relationships.It enriches the theoretical system related to family education and has important theoretical and practical implications for further interventions on adolescents’mental health from the perspective of fatherless parenting.展开更多
A series of high surface area graphitic carbon materials （HSGCs） were prepared by ball-milling method. Effect of the graphitic degree of HSGCs on the catalytic performance of Ba-Ru-K/HSGC-x （x is the ball-milling t...A series of high surface area graphitic carbon materials （HSGCs） were prepared by ball-milling method. Effect of the graphitic degree of HSGCs on the catalytic performance of Ba-Ru-K/HSGC-x （x is the ball-milling time in hour） catalysts was studied using ammonia synthesis as a probe reaction. The graphitic degree and pore structure of HSGC-x supports could be successfully tuned via the variation of ball-milling time. Ru nanoparticles of different Ba-Ru-K/HSGC-x catalysts are homogeneously distributed on the supports with the particle sizes ranging from 1.6 to 2.0 nm. The graphitic degree of the support is closely related to its facile electron transfer capability and so plays an important role in improving the intrinsic catalytic performance of Ba-Ru-K/HSGC-x catalyst.展开更多
Molecular nitrogen is relatively inert and the activation of its triple bond is full of challenges and of significance.Hence,searching for an efficiently heterogeneous catalyst with high stability and dispersion is on...Molecular nitrogen is relatively inert and the activation of its triple bond is full of challenges and of significance.Hence,searching for an efficiently heterogeneous catalyst with high stability and dispersion is one of the important targets of chemical technology.Here,we report a Ba‐K/Ru‐MC catalyst with Ru particle size of 1.5–2.5 nm semi‐embedded in a mesoporous C matrix and with dual promoters of Ba and K that exhibits a higher activity than the supported Ba‐Ru‐K/MC catalyst,although both have similar metal particle sizes for ammonia synthesis.Further,the Ba‐K/Ru‐MC catalyst is more active than commercial fused Fe catalysts and supported Ru catalysts.Characterization techniques such as high‐resolution transmission electron microscopy,N2 physisorption,CO chemisorption,and temperature‐programmed reduction suggest that the Ru nanoparticles have strong interactions with the C matrix in Ba‐K/Ru‐MC,which may facilitate electron transport better than supported nanoparticles.展开更多
The carbonization process of a sucrose‐RuCl3/SBA‐15composite towards a Ru‐containing ordered mesoporous carbon(Ru‐OMC)catalyst was studied by in situ temperature‐programmed infrared spectroscopy to identify the s...The carbonization process of a sucrose‐RuCl3/SBA‐15composite towards a Ru‐containing ordered mesoporous carbon(Ru‐OMC)catalyst was studied by in situ temperature‐programmed infrared spectroscopy to identify the stabilization role of organic carbon precursors during the formation of highly dispersed Ru nanoparticles.The results show that the formation of metal carbonyl species results in the formation of homogeneously distributed Ru nanoparticles,and the rigid silica support and carbon matrix around the Ru(CO)x complex can significantly avoid the sintering and agglomeration of Ru metal particles during elevated temperature thermal treatment.These results ultimately demonstrate that sucrose plays important roles in the formation of homogeneously distributed Ru nanoparticles in a porous carbon matrix.?2018,Dalian Institute of Chemical Physics,Chinese Academy of Sciences.Published by Elsevier B.V.All rights reserved.展开更多
Salt bladders,specialized structures on the surface of quinoa leaves,secrete Na+to mitigate the effects of the plant from abiotic stresses,particularly salt exposure.Understanding the development of these structures i...Salt bladders,specialized structures on the surface of quinoa leaves,secrete Na+to mitigate the effects of the plant from abiotic stresses,particularly salt exposure.Understanding the development of these structures is crucial for elucidating quinoa’s salt tolerance mechanisms.In this study,we employed transmission electron microscopy to detail cellular differentiation across the developmental stages of quinoa salt bladders.To further explore the developmental trajectory and underlying molecular mechanisms,we conducted single-cell RNA sequencing on quinoa protoplasts derived from young leaves.This allowed us to construct a cellular atlas,identifying 13 distinct cell clusters.Through pseudotime analysis,we mapped the developmental pathways of salt bladders and identified regulatory factors involved in cell fate decisions.GO and KEGG enrichment analyses,as well as experimental results,revealed the impacts of salt stress and the deprivation of sulfur and nitrogen on the development of quinoa salt bladders.Analysis of the transcription factor interaction network in pre-stalk cells(pre-SC),stalk cells(SC),and epidermal bladder cells(EBCs)indicated that TCP5,YAB5,NAC078,SCL8,GT-3B,and T1P17.40 play crucial roles in EBC development.Based on our findings,we developed an informative model elucidating salt bladder formation.This study provides a vital resource for mapping quinoa leaf cells and contributes to our understanding of its salt tolerance mechanisms.展开更多
The regulation of stomatal lineage cell development has been extensively investigated.However,a comprehensive characterization of this biological process based on single-cell transcriptome analysis has not yet been re...The regulation of stomatal lineage cell development has been extensively investigated.However,a comprehensive characterization of this biological process based on single-cell transcriptome analysis has not yet been reported.In this study,we performed RNA sequencing on 12844 individual cells from the cotyledons of 5-day-old Arabidopsis seedlings.We identified 11 cell clusters corresponding mostly to cells at specific stomatal developmental stages using a series of marker genes.Comparative analysis of genes with the highest variable expression among these cell clusters revealed transcriptional networks that regulate development from meristemoid mother cells to guard mother cells.Examination of the developmental dynamics of marker genes via pseudo-time analysis revealed potential interactions between these genes.Collectively,our study opens the door for understanding how the identified novel marker genes participate in the regulation of stomatal lineage cell development.展开更多
Gastrodia elata Bl.is traditional Chinese medicine used to alleviate fatigue,but its underlying mechanism is still unclear.This study explored the anti-fatigue mechanism of gastrodin by exercise-induced fatigue model ...Gastrodia elata Bl.is traditional Chinese medicine used to alleviate fatigue,but its underlying mechanism is still unclear.This study explored the anti-fatigue mechanism of gastrodin by exercise-induced fatigue model and network pharmacology.This study found that gastrodin(200 mg/kg/day)had significant anti-fatigue effects in C57BL/6J mice based on mouse energy and endurance measurements.Gastrodin could effectively ameliorate biochemical indexes in the fatigue mice.The putative targets of“Gastrodin”and“Fatigue”were obtained by integrating multiple databases,and a virtual network containing 220 interactive targets was constructed by STRING and Cytoscape.Functional annotation analysis of these targets by g:Profiler showed that they mainly contribute to the cellular processes,protein binding,and other functions and participate in metabolic pathways,cancer pathways,PI3K-Akt signaling pathway,etc.We found that oxidation and inflammatory factors played an important role in the virtual network of gastrodin anti-fatigue,which was supported by microarray dataset analysis and a molecular docking prediction.Additionally,real time-quantitative PCR and Western blot analysis indicated that gastrodin could promote the activation of the Nrf2 signal pathway,which could activate HO-1 and NQO1;gastrodin also could down-regulate the expressions of IL-1β,TNF-α,and IL-6.In summary,gastrodin can ameliorate exercise-induced fatigue by modulating the Nrf2 pathway and inhibiting expressions of inflammatory factors,this provides a new clue for the development of gastrodin-functional foods or anti-fatigue drugs.展开更多
Octacosanol is a widely distributed natural higher aliphatic alcohol that can be isolated and purified from rice bran,sugarcane,beeswax,insect wax,etc.Octacosanol exerts various biological effects,including anti-fatig...Octacosanol is a widely distributed natural higher aliphatic alcohol that can be isolated and purified from rice bran,sugarcane,beeswax,insect wax,etc.Octacosanol exerts various biological effects,including anti-fatigue,anti-hypoxia,antioxidant,anti-inflammatory,antitumor,etc.Meanwhile,it has the effects of regulating the body's immune function and energy metabolism and has potential benefits for cardiovascular disease,cerebrovascular disorders,diabetes,Parkinson's disease,and others.Octacosanol is primarily responsible for regulating multiple signaling pathways,such as AMPK,PI3K/Akt,and MAPK/NF-κB,to achieve different physiological functions.This review systemically summarized the progress in characterization,extraction and purification,biological functions,molecular mechanisms,and bioavailability of octacosanol.This study will provide a reference for many investigators to further explore the physiological functions of higher aliphatic alcohols and apply them as supplements in functional foods.展开更多
Activated carbon with high specific surface area and considerable mesopores was prepared from bamboo scraps by phosphoric acid activation.The effect of activation conditions was studied.Under the conditions of impregn...Activated carbon with high specific surface area and considerable mesopores was prepared from bamboo scraps by phosphoric acid activation.The effect of activation conditions was studied.Under the conditions of impregnating bamboo with 80%H3PO_(4) at 80℃ for 9 days and activation at 500℃ for 4 h,the prepared activated carbon had the highest mesopore volume of 0.67 cm3/g,a specific surface area of 1567 m2/g,and the mesopore ratio reached 47.18%.The study on adsorption isotherms of CH4,CO_(2),N2 and O_(2) on the activated carbon were carried out at 298 K.The considerable difference in the adsorption capacity between CO_(2) and the other gases was observed,which would be of interest for the adsorptive separation/purification of gaseous CO_(2) from its mixtures,especially from mixtures with N2 and/or O_(2).展开更多
基金financially supported by Key Project of State Key R&D Program,China (2022YFF1100200)the Program for Science&Technology Innovation Platform of Hunan Province (2019TP102)+3 种基金Natural Science Foundation of Hunan Province (2021JJ31075,2019JJ50984)Natural Science Foundation of Changsha City (kq2014275)Scientific Innovation Fund for Postgraduates of Central South University of Forestry and Technology (CX20200699,CX202102067)Postgraduate Scientific Research Innovation Project of Hunan Province (CX20201018,CX20210899,CX20220701 and CX20220720)。
文摘Dietary parboiled rice(PR)has a low risk of disease,but little is known about the contribution of PR to the prevention of hyperlipidemia.The potential role and underlying mechanisms of PR in hyperlipidemia were evaluated in this study.Male C57BL/6J mice were fed with a normal diet,high-fat diet(HFD)containing refined rice(HFDRR)or PR(HFDPR).It was found that PR intervention improved lipid accumulation in mice.Transcriptomic data analysis revealed that 27 genes were up-regulated(mostly involved in lipid breakdown)and 86 genes were down-regulated(mostly involved in inflammatory responses)in the HFDPR group compared to the HFDRR group.And 15 differentially expressed genes(DEGs)were validated by quantitative real-time PCR(RT-qPCR),while protein interaction network showed that protein tyrosine phosphatase receptor type C(PTPRC)has a central role.The gut microbiota of mice was also altered after different dietary treatments,with higher ratio of Firmicutes and Bacteroidetes,increased abundances of Ruminococcaceae,Lachnospiraceae,Christensenellaceae,Porphyromonadaceae,Rikenellaceae and Prevotellaceae,and decreased abundances of Lactobacillaceae,Peptostreptococcaceae,Erysipelotrichaceae and Actinobacteria in the HFDRR group.In addition,it was observed that PPAR signaling pathway may act as a bridge between DEGs and differential gut microbiota.These results suggested that PR can prevent hyperlipidemia by modulating liver genes and gut microbiota.
基金the Project of National Education Scientific Planning Projects of China,DBA180316.
文摘Childhood maltreatment,as a typical early adverse environment,is known to have a negative impact on one’s life satisfaction.Mindfulness,on the other hand,may serve as a protective factor.This study explored the mediating role of mindfulness and its related variables–positive thoughts,psychological resilience and self-esteem.In order to testify the mechanism,we administered Childhood Trauma Questionnaire(CTQ),Satisfaction with Life Scale(SWLS),Mindful Attention Awareness Scale(MAAS),Connor–Davidson Resilience Scale(CD-RISC)and Rosenberg Self-Esteem Scale(RSES)to a non-clinical sample of Chinese university students(N=1021).The results indicated that positive thoughts did not mediate the relationship between childhood maltreatment and life satisfaction,but self-esteem(β=−0.194,95%CI=[−0.090,−0.040])and psychological resilience(β=−0.063,95%CI=[−0.059,−0.020])mediated the relationship,as well as the“mindfulness-selfesteem”(β=−0.061,95%CI=[−0.287,−0.126])and“mindfulness-psychological resilience”(β=−0.035,95%CI=[−0.115,−0.034]).The results of this study were helpful to understand the relationship between childhood maltreatment and life satisfaction and provided a theoretical basis for the development of mindfulness intervention programs from the perspective of positive psychology.
基金the General Program of the National Socail Science Fund of China(23BSH144).
文摘Fathers play an important role in adolescents’development,which is significant for their development and influences their mental health,including feeling of loneliness.However,the effects and mechanisms of father-love absence on individual loneliness are not clear.Based on the social functionalist theory and the social needs theory,this study examines the influence of individual fatherlove absence on loneliness and its underlying mechanisms.A questionnaire survey was administered to 319 junior high school students and 1,476 high school students.The results showed that adolescents with father-love absence had higher levels of loneliness,and that father-love absence affected loneliness levels through mediating pathways of individual gratitude,peer relationships,and gratitude to peer relationships.This study not only confirms the negative effects of father-love absence on adolescents’loneliness,but also explains the mediate roles of individual gratitude and peer relationships.It enriches the theoretical system related to family education and has important theoretical and practical implications for further interventions on adolescents’mental health from the perspective of fatherless parenting.
基金supported by the Natural Science Foundation of China(NSFC Grant No.20803064)the Natural Science Foundation of Zhejiang Provence(Y4090348 and LY12B03007)Qianjiang Talent Project in Zhejiang Province(2010R10039 and 2013R10056)
文摘A series of high surface area graphitic carbon materials （HSGCs） were prepared by ball-milling method. Effect of the graphitic degree of HSGCs on the catalytic performance of Ba-Ru-K/HSGC-x （x is the ball-milling time in hour） catalysts was studied using ammonia synthesis as a probe reaction. The graphitic degree and pore structure of HSGC-x supports could be successfully tuned via the variation of ball-milling time. Ru nanoparticles of different Ba-Ru-K/HSGC-x catalysts are homogeneously distributed on the supports with the particle sizes ranging from 1.6 to 2.0 nm. The graphitic degree of the support is closely related to its facile electron transfer capability and so plays an important role in improving the intrinsic catalytic performance of Ba-Ru-K/HSGC-x catalyst.
基金supported by the National Natural Science Foundation of China(20803064)the Natural Science Foundation of Zhejiang Provence(LY17B030010)~~
文摘Molecular nitrogen is relatively inert and the activation of its triple bond is full of challenges and of significance.Hence,searching for an efficiently heterogeneous catalyst with high stability and dispersion is one of the important targets of chemical technology.Here,we report a Ba‐K/Ru‐MC catalyst with Ru particle size of 1.5–2.5 nm semi‐embedded in a mesoporous C matrix and with dual promoters of Ba and K that exhibits a higher activity than the supported Ba‐Ru‐K/MC catalyst,although both have similar metal particle sizes for ammonia synthesis.Further,the Ba‐K/Ru‐MC catalyst is more active than commercial fused Fe catalysts and supported Ru catalysts.Characterization techniques such as high‐resolution transmission electron microscopy,N2 physisorption,CO chemisorption,and temperature‐programmed reduction suggest that the Ru nanoparticles have strong interactions with the C matrix in Ba‐K/Ru‐MC,which may facilitate electron transport better than supported nanoparticles.
基金supported by the Natural Science Foundation of Zhejiang Province(LY17B030010)~~
文摘The carbonization process of a sucrose‐RuCl3/SBA‐15composite towards a Ru‐containing ordered mesoporous carbon(Ru‐OMC)catalyst was studied by in situ temperature‐programmed infrared spectroscopy to identify the stabilization role of organic carbon precursors during the formation of highly dispersed Ru nanoparticles.The results show that the formation of metal carbonyl species results in the formation of homogeneously distributed Ru nanoparticles,and the rigid silica support and carbon matrix around the Ru(CO)x complex can significantly avoid the sintering and agglomeration of Ru metal particles during elevated temperature thermal treatment.These results ultimately demonstrate that sucrose plays important roles in the formation of homogeneously distributed Ru nanoparticles in a porous carbon matrix.?2018,Dalian Institute of Chemical Physics,Chinese Academy of Sciences.Published by Elsevier B.V.All rights reserved.
基金supported by the National Key Research and Development Program of China(No.2022YFD1200300).
文摘Salt bladders,specialized structures on the surface of quinoa leaves,secrete Na+to mitigate the effects of the plant from abiotic stresses,particularly salt exposure.Understanding the development of these structures is crucial for elucidating quinoa’s salt tolerance mechanisms.In this study,we employed transmission electron microscopy to detail cellular differentiation across the developmental stages of quinoa salt bladders.To further explore the developmental trajectory and underlying molecular mechanisms,we conducted single-cell RNA sequencing on quinoa protoplasts derived from young leaves.This allowed us to construct a cellular atlas,identifying 13 distinct cell clusters.Through pseudotime analysis,we mapped the developmental pathways of salt bladders and identified regulatory factors involved in cell fate decisions.GO and KEGG enrichment analyses,as well as experimental results,revealed the impacts of salt stress and the deprivation of sulfur and nitrogen on the development of quinoa salt bladders.Analysis of the transcription factor interaction network in pre-stalk cells(pre-SC),stalk cells(SC),and epidermal bladder cells(EBCs)indicated that TCP5,YAB5,NAC078,SCL8,GT-3B,and T1P17.40 play crucial roles in EBC development.Based on our findings,we developed an informative model elucidating salt bladder formation.This study provides a vital resource for mapping quinoa leaf cells and contributes to our understanding of its salt tolerance mechanisms.
基金This research was supported by the National Natural Science Foundation of China(31670233)the Key Scientific and Technological Projects in Henan Province,China(192102110113).
文摘The regulation of stomatal lineage cell development has been extensively investigated.However,a comprehensive characterization of this biological process based on single-cell transcriptome analysis has not yet been reported.In this study,we performed RNA sequencing on 12844 individual cells from the cotyledons of 5-day-old Arabidopsis seedlings.We identified 11 cell clusters corresponding mostly to cells at specific stomatal developmental stages using a series of marker genes.Comparative analysis of genes with the highest variable expression among these cell clusters revealed transcriptional networks that regulate development from meristemoid mother cells to guard mother cells.Examination of the developmental dynamics of marker genes via pseudo-time analysis revealed potential interactions between these genes.Collectively,our study opens the door for understanding how the identified novel marker genes participate in the regulation of stomatal lineage cell development.
基金supported by Program for Science&Technology Innovation Platform of Hunan Province(2019TP102)Graduate Innovative Research Project of Hunan province and Central South University of Forestry and Technology(CX20210862,CX202101027)Science and Technology Plan Project of Changsha City(kq2014275).
文摘Gastrodia elata Bl.is traditional Chinese medicine used to alleviate fatigue,but its underlying mechanism is still unclear.This study explored the anti-fatigue mechanism of gastrodin by exercise-induced fatigue model and network pharmacology.This study found that gastrodin(200 mg/kg/day)had significant anti-fatigue effects in C57BL/6J mice based on mouse energy and endurance measurements.Gastrodin could effectively ameliorate biochemical indexes in the fatigue mice.The putative targets of“Gastrodin”and“Fatigue”were obtained by integrating multiple databases,and a virtual network containing 220 interactive targets was constructed by STRING and Cytoscape.Functional annotation analysis of these targets by g:Profiler showed that they mainly contribute to the cellular processes,protein binding,and other functions and participate in metabolic pathways,cancer pathways,PI3K-Akt signaling pathway,etc.We found that oxidation and inflammatory factors played an important role in the virtual network of gastrodin anti-fatigue,which was supported by microarray dataset analysis and a molecular docking prediction.Additionally,real time-quantitative PCR and Western blot analysis indicated that gastrodin could promote the activation of the Nrf2 signal pathway,which could activate HO-1 and NQO1;gastrodin also could down-regulate the expressions of IL-1β,TNF-α,and IL-6.In summary,gastrodin can ameliorate exercise-induced fatigue by modulating the Nrf2 pathway and inhibiting expressions of inflammatory factors,this provides a new clue for the development of gastrodin-functional foods or anti-fatigue drugs.
基金supported by the[National Natural Science Foundation of China]under Grant[number 31571874][the Grain-oil Process and Quality Control 2011 Collaborative and Innovative Grant from Hunan Province]under Grant[2013,number 448]+1 种基金[the Key Project of the Education Department of Hunan Province]under Grant[number 16A228,13A124][the Graduate Innovative Research Project of Hunan province and Central South University of Forestry and Technology]under Grant[number CX20200699,CX20201018].
文摘Octacosanol is a widely distributed natural higher aliphatic alcohol that can be isolated and purified from rice bran,sugarcane,beeswax,insect wax,etc.Octacosanol exerts various biological effects,including anti-fatigue,anti-hypoxia,antioxidant,anti-inflammatory,antitumor,etc.Meanwhile,it has the effects of regulating the body's immune function and energy metabolism and has potential benefits for cardiovascular disease,cerebrovascular disorders,diabetes,Parkinson's disease,and others.Octacosanol is primarily responsible for regulating multiple signaling pathways,such as AMPK,PI3K/Akt,and MAPK/NF-κB,to achieve different physiological functions.This review systemically summarized the progress in characterization,extraction and purification,biological functions,molecular mechanisms,and bioavailability of octacosanol.This study will provide a reference for many investigators to further explore the physiological functions of higher aliphatic alcohols and apply them as supplements in functional foods.
文摘Activated carbon with high specific surface area and considerable mesopores was prepared from bamboo scraps by phosphoric acid activation.The effect of activation conditions was studied.Under the conditions of impregnating bamboo with 80%H3PO_(4) at 80℃ for 9 days and activation at 500℃ for 4 h,the prepared activated carbon had the highest mesopore volume of 0.67 cm3/g,a specific surface area of 1567 m2/g,and the mesopore ratio reached 47.18%.The study on adsorption isotherms of CH4,CO_(2),N2 and O_(2) on the activated carbon were carried out at 298 K.The considerable difference in the adsorption capacity between CO_(2) and the other gases was observed,which would be of interest for the adsorptive separation/purification of gaseous CO_(2) from its mixtures,especially from mixtures with N2 and/or O_(2).
