Transient simulation are more economical and adaptable means of studying lightning overvoltage for overhead distribution line system compared to experiments.A hybrid multi-transmission-line(MTL)-partial element equiva...Transient simulation are more economical and adaptable means of studying lightning overvoltage for overhead distribution line system compared to experiments.A hybrid multi-transmission-line(MTL)-partial element equivalent circuit(PEEC)method proposed for lightning-induced electromagnetic pulse(LEMP)simulation is verified using the rocket-triggered experimental results under a more complex line configuration for the first time.This method can improve computational efficiency while ensuring calculation accuracy.The agreement between experimental and simulation results further validates the adaptability and accuracy of the proposed method,which is adopted to calculate the LEMP on the extended double-circuit parallel unequal length line.The effects of various factors,such as the strike-point location,the amplitude and waveform of the lightning current,the line shape and length on the amplitude of overvoltage and pole flashover along the line are discussed.For double-circuit distribution lines,when lightning strikes the ground in front of centre of circuit I,the three-phase voltage waveforms are similar,all of which are negative or bipolar oscillation waves.The closer the lightning strike point is to the line,the greater the amplitude of the lightning current,and the voltage waveform develops towards a bipolar waveform,but the main peak remains negative.As the amplitude of lightning current increases,the maximum lightning-induced voltage amplitude along the line increases.The LEMP caused by the subsequent return-stroke current is always greater than that caused by the first returnstroke current.When the grounding resistance increases,the maximum voltage peak amplitude along the line remains unchanged.展开更多
Low iron content is a peculiar feature of marine ecosystems,where microbes have to produce iron-chelating molecules such as siderophores to survive.Very little is known about siderophore-producing bacteria in the ocea...Low iron content is a peculiar feature of marine ecosystems,where microbes have to produce iron-chelating molecules such as siderophores to survive.Very little is known about siderophore-producing bacteria in the oceans.In this study,we screened 1546 strains from marine seawater and sediments,which were deposited in the Marine Culture Collection of China(MCCC),and further analyzed the diversity of positive strains and their potential genes related to iron acquisition.Of the 1546 isolates,856 strains(55.37%)showed positive siderophore-producing activity on the Chrome Azurol Sulfonate(CAS)plates.Among these,isolates from seawater environments had a higher positive proportion(535).Some genera showed a higher proportion(>70%)of positive siderophore producers,such as Alteromonas(89/112),Marinobacter(78/109),Vibrio(21/27),Shewanella(7/8)in the Gammaproteobacteria,Sulfitobacter(17/21),Martelella(5/6)in the Alphaproteobacteria,and Joostella(6/7)in the phylum Bacteroidetes.Siderophore biosynthesis genes,including those for vanchrobactin,vibrioferrin,petrobactin,and aerobactin,as well as transport and iron storage proteins,were also identified in the positive bacterial genomes.The study revealed that a variety of bacterial strains demonstrate the production of siderophores,which could significantly contribute to the iron cycle within marine ecosystems,encompassing both seawater and marine sediments.展开更多
Solid lithium-ion-conducting material is the key component in the fabrication of next-gene ration all solid state lithium ion batteries(LIBs)which would exhibit superior safety and performance compared with the curren...Solid lithium-ion-conducting material is the key component in the fabrication of next-gene ration all solid state lithium ion batteries(LIBs)which would exhibit superior safety and performance compared with the currently widely used ones that resort to essentially inflammable and volatile organic solvents.To date,great efforts have been made in developing solid conductors with high lithium ion conductivity,such as polymers and inorganic materials.Rare earths play a very important role in this area and have attracted extensive interest since the recent decades for their unique properties in the realm of solidstate inorganic lithium-ion-conducting electrolyte materials.In this introduction,we focus on the role of rare earths in solid conductors for lithium ion,especially in a few most studied systems such as perovskites,garnets,silicates,borohydride and the recently reported halides in which rare earths act as a key framing component.Besides,the effect of rare earths as dopants is also discussed in some recently studied systems.Valence,coordination,and size are the most important factors that influence the crystal structure and property of these lithium ion conductors.The aim of this review is to highlight the great potentials of these unique elements of rare earths,and to help improve the performance of existing materials and explore new applications in the development of new LIBs with high performances.展开更多
The construction of rare earth(RE)alloy catalysts offers a route to harness the unique electronic structure of RE.Within the alloy,RE can fine-tune the electronic configuration of the active element,such as rhodium(Rh...The construction of rare earth(RE)alloy catalysts offers a route to harness the unique electronic structure of RE.Within the alloy,RE can fine-tune the electronic configuration of the active element,such as rhodium(Rh),via the ligand effect,optimizing the electrochemical reaction pathway.However,the challenging negative reduction potential of RE has impeded the progress in developing RE alloys,particularly nanoalloy catalysts.In this study,Rh_(3)Sc/C and Rh_(3)Y/C nanoalloys were synthesized using a sodium vapor reduction strategy for application as hydrogen evolution reaction(HER)catalysts.Elec-trochemical tests reveal that Rh-RE alloy catalysts exhibit significantly improved electrocatalytic activity in 1 mol/L KOH.Notably,Rh_(3)Y/C demonstrates exceptional HER performance,achieving a low over-potential of only 31 mV at 10 mA/cm^(2),surpassing the 50 mV observed for Rh/C.Furthermore,the current density of Rh_(3)Y/C at an 80 mV overpotential is 3.9 times that of Rh/C.This study sheds light on the remarkable catalytic potential of Rh-RE alloys,paving the way for the future expansion of RE nanoalloy systems.展开更多
Applying a stimulating current to acupoints through acupuncture needles–known as electroacupuncture–has the potential to produce analgesic effects in human subjects and experimental animals. When acupuncture was app...Applying a stimulating current to acupoints through acupuncture needles–known as electroacupuncture–has the potential to produce analgesic effects in human subjects and experimental animals. When acupuncture was applied in a rat model, adenosine 5-triphosphate disodium in the extracellular space was broken down into adenosine, which in turn inhibited pain transmission by means of an adenosine A1 receptor-dependent process. Direct injection of an adenosine A1 receptor agonist enhanced the analgesic effect of acupuncture. The analgesic effect of acupuncture appears to be mediated by activation of A1 receptors located on ascending nerves. In neuropathic pain, there is upregulation of P2X purinoceptor 3 （P2X3） receptor expression in dorsal root ganglion neurons. Conversely, the onset of mechanical hyperalgesia was diminished and established hyperalgesia was significantly reversed when P2X3 receptor expression was downregulated. The pathways upon which electroacupuncture appear to act are interwoven with pain pathways, and electroacupuncture stimuli converge with impulses originating from painful areas. Electroacupuncture may act via purinergic A1 and P2X3 receptors simultaneously to induce an analgesic effect on neuropathic pain.展开更多
IrOx-based catalysts are considered the most promising candidates for oxygen evolution reaction(OER)due to their high efficiency.However,improving their intrinsic catalytic activity is essential for practical applicat...IrOx-based catalysts are considered the most promising candidates for oxygen evolution reaction(OER)due to their high efficiency.However,improving their intrinsic catalytic activity is essential for practical application.In this work,CeO_(2)with three different morphologies(rod,cube,octahedron)and supported IrOx nanoparticles were fabricated,and they display morphology-dependent OER activity.The IrOx/CeO_(2)-rod shows the highest activity;the catalysts have a catalytic activity sequence of rod>cube>octahedron.A plausible mechanism was proposed:the CeO_(2)support with different morphologies modulates the electronic structure of IrOx by the synergistic interaction promoted by oxygen vacancies between the active component and the support,thereby altering the catalytic activity of the IrOx/CeO_(2)catalyst.展开更多
For wound healing,wound infection caused by bacteria is one of the important reasons that delay wound healing process.Therefore,it is very meaningful to develop a multifunctional wound dressing with antibacterial capa...For wound healing,wound infection caused by bacteria is one of the important reasons that delay wound healing process.Therefore,it is very meaningful to develop a multifunctional wound dressing with antibacterial capability to accelerate wound healing.Sodium alginate(SA)and carboxymethyl chitosan(CMCS)are the most commonly used compositions in wound dressing,but their poor stability inhibits the further applications.Introducing CMCS and using cerium ions(Ce^(3+))to crosslink CMCS and SA to form SA-CMCS hybrid spheres by electrostatic spray method,can not only improve the stability of SA hydrogels,but also endow the spheres with excelle nt antibacterial properties due to the characteristics of Ce^(3+).The gradual release of Ce^(3+)from the SA-CMCS spheres can effectively inhibit the growth of Staphylococcus aureus(S.aureus)and Escherichia coli(E.coli).Combining the wound healing promotion ability of SA and CMCS,this kind of wound dressing can not only avoid wound infection caused by bacteria effectively,but also accelerate wound healing,thus it is an easily prepared material with potential applications in skin defect repair.展开更多
Currently,single-atom combo catalysts(SACCs)for carbon dioxide reduction reaction(CO_(2)RR)to the formation of HCOOH are still very limited,especially the lanthanide-based SACCs.In this work,the novel SACCs with atomi...Currently,single-atom combo catalysts(SACCs)for carbon dioxide reduction reaction(CO_(2)RR)to the formation of HCOOH are still very limited,especially the lanthanide-based SACCs.In this work,the novel SACCs with atomically dispersed In and Ce active sites were successfully prepared on the nitrogen-doped carbon matrix(InCe/CN).Both aberration-corrected high-angle annular dark-field scanning transmission electron microscopy(AC-HAADF-STEM)images and the extended X-ray absorption fine structure(EXAFS)spectra proved the well-isolated In and Ce atoms.The as-prepared InCe/CN shows a high Faradaic efficiency(FE)(77%)and current density of HCOOH formation(j_(HCOOH))at-1.35 V vs.reversible hydrogen electrode(RHE),much higher than the single atom catalysts.Theoretical calculations have indicated that the introduced Ce single atom sites not only significantly promote electron transfer but also optimize the In-5p orbitals towards higher selectivity towards the HCOOH formation.This work innovatively extends the design of SACCs towards the main group and Ln metals for more applications.展开更多
Developments of nanostructured transition metal dichalcogenides （TMDs） materials as novel electrocatalyst candidates for oxygen reduction reaction （ORR） is a new strategy to promote the developments of non-preciou...Developments of nanostructured transition metal dichalcogenides （TMDs） materials as novel electrocatalyst candidates for oxygen reduction reaction （ORR） is a new strategy to promote the developments of non-precious metal ORR catalysts. In this work, a three-dimensional （3D） hybrid of rosebud-like MoSe2 nanostructures supported on reduced graphene oxide （rGO） nanosheets was successfully synthesized through a facile hydrothermal strategy. The prepared MoSe2@rGO hybrid nanostructure showed enhanced electrocatalytic activity for the ORR in alkaline medium compared to that of the pure MoSe2, rGO, and their simple physical mixture, which could benefit from the excellent oxygen adsorption ability of the abundantly exposed active edge sites of the ultrathin MoSe2 layers, the conductivity and aggregation-limiting effect of the rGO platform, as well as the unique 3D rosebud-like architecture of the hybrid material. The electrocatalytic activity of the MoSe2@rGO hybrid towards ORR was comparable to that of com- inertial Pt/C catalysts. And the promoted reaction was revealed to involve a nearly four-electron-dominated ORR process by analysis of the obtained Koutecky- Levich plots. The scanning electrochemical microscopy （SECM） technique, with the advantages of investigating of the local catalytic activity of samples with high spatial resolution and simultaneously evaluating activities of different catalysts in a single experiment, was further applied to investigate the local ORR electrocatalytic activity of MoSe2@rGO and compare it with those of other catalyst samples through applying different sample potentials. The excellent stability and methanol tolerance of the 3D nanostructured MoSe2@rGO hybrid against methanol further prove the 3D nanostructured MoSe2@rGO hybrid as a promising ORR electrocatalyst in alkaline solution for potential applications in fuel cells and metal-air batteries.展开更多
Rare-earth(RE)halide solid electrolytes(HSEs)have been an emerging research area due to their good electrochemical and mechanical properties for all-solid-state lithium batteries(ASSBs).However,only very limited types...Rare-earth(RE)halide solid electrolytes(HSEs)have been an emerging research area due to their good electrochemical and mechanical properties for all-solid-state lithium batteries(ASSBs).However,only very limited types of HSEs have been reported with high performance.In this work,tens of grams of RE-HSE Li_(3)TbBr_(6)(LTbB)was synthesized by a vacuum evaporationassisted method.The as-prepared LTbB displays a high ionic conductivity of 1.7 mS·cm^(-1),a wide electrochemical window,and good formability.Accordingly,the assembled solid lithium-tellurium(Li-Te)battery based on the LTbB HSE exhibits excellent cycling stability up to 600 cycles,which is superior to most previous reports.The processes and the chemicals during the discharge/charge of Li-Te batteries have been studied by various in situ and ex situ characterizations.Theoretical calculations have demonstrated the dominant conductivity contributions of the direct[octahedral]-[octahedral]([Oct]-[Oct])pathway for Li ion migrations in the electrolyte.The Tb sites guarantee efficient electron transfer while the Li 2s orbitals are not affected during migration,leading to a low activation barrier.Therefore,this successful fabrication and application of LTbB have offered a highly competitive solution for solid electrolytes in ASSBs,indicating the great potential of RE-based HSEs in energy devices.展开更多
Currently,dual atomic catalysts(DACs)with neighboring active sites for oxygen reduction reaction(ORR)still meet lots of challenges in the synthesis,especially the construction of atomic pairs of elements from differen...Currently,dual atomic catalysts(DACs)with neighboring active sites for oxygen reduction reaction(ORR)still meet lots of challenges in the synthesis,especially the construction of atomic pairs of elements from different blocks of the periodic table.Herein,a“rare earth(Ce)-metalloid(Se)”non-bonding heteronuclear diatomic electrocatalyst has been constructed for ORR by rational coordination and carbon support defect engineering.Encouraging,the optimized Ce-Se diatomic catalysts(Ce-Se DAs/NC)displayed a half-wave potential of 0.886 V vs.reversible hydrogen electrode(RHE)and excellent stability,which surpass those of separate Ce or Se single atoms and most single/dual atomic catalysts ever reported.In addition,a primary zinc-air battery constructed using Ce-Se DAs/NC delivers a higher peak power density(209.2 mW·cm^(−2))and specific capacity(786.4 mAh·gZn^(−1))than state-of-the-art noble metal catalysts Pt/C.Theoretical calculations reveal that the Ce-Se DAs/NC has improved the electroactivity of the Ce-N_(4)region due to the electron transfer towards the nearby Se specific activity(SA)sites.Meanwhile,the more electron-rich Se sites promote the adsorptions of key intermediates,which results in the optimal performances of ORR on Ce-Se DAs/NC.This work provides new perspectives on electronic structure modulations via non-bonded long-range coordination micro-environment engineering in DACs for efficient electrocatalysis.展开更多
Heterophase nanomaterials composed of multiple phases have attracted increasing attention due to their enhanced performance in electrocatalytic field.Nevertheless,constructing two-dimensional(2D)crystalline/amorphous ...Heterophase nanomaterials composed of multiple phases have attracted increasing attention due to their enhanced performance in electrocatalytic field.Nevertheless,constructing two-dimensional(2D)crystalline/amorphous heterophase nanostructures with the samechemical composition remains a great challenge.Herein,we report the preparation of a 2D crystalline/amorphous heterophase of MoS2 nanosheets with the same elemental components via a facile solvothermal method.展开更多
Metabolism,transpiration,and invasion of pathogens during the storage and transportation of fruits can lead to significant waste and even food safety issues.Therefore,real-time,rapid,and accurate non-destructive monit...Metabolism,transpiration,and invasion of pathogens during the storage and transportation of fruits can lead to significant waste and even food safety issues.Therefore,real-time,rapid,and accurate non-destructive monitoring of physiological information during the storage of fruits and vegetables to assess fruit freshness is crucial.Herein,we engineered a degradable and multifunctional humidity sensing film for monitoring fruit freshness.The film is fabricated through the co-assembly of bagasse cellulose nanocrystals(CNC),okra polysaccharides(OPs),silver nanowires(Ag NWs),and phytic acid(PA),utilizing dynamic hydrogen and phosphate bonds.This innovative design endows the CNC/OPs/PA/Ag NWs(COPA)composite film with outstanding mechanical properties,water resistance,low water vapor permeability,antibacterial,degradability,and moisture-sensing ability.Notably,the proposed COPA humidity sensor exhibits high linearity(R^(2)=0.994),ultralow hysteresis(1.24%),and 32 days of operational stability across a 35%–98%relative humidity(RH)range,enabling precise freshness monitoring during fruit storage.Significantly,the COPA film prolonged the shelf-life of packaged fruit when compared to conventional PE film packaging.This research establishes a foundational framework for next-generation smart sensors in food quality management and biomedical monitoring applications.展开更多
Nanomaterials have been applied as antibacterial agents by virtue of their unique functioning mechanism different from that of conventional antibiotics.Cerium oxide nanoparticles(CeO2 NPs)are important antibacterial a...Nanomaterials have been applied as antibacterial agents by virtue of their unique functioning mechanism different from that of conventional antibiotics.Cerium oxide nanoparticles(CeO2 NPs)are important antibacterial agents due to their relatively low toxicity to normal cells and their distinct antibacterial mechanism based on the reversible conversion between two valence states of Ce(III)/Ce(IV).Some studies have been conducted to explore their antibacterial activities;however,systematic research reviews on the related mechanisms and influencing factors are still quite rare.In this review,we discuss the plausible mechanisms of the antibacterial activity of CeO2 NPs,analyze different influencing factors,and summarize various research reports on antibacterial effects on E.coli and S.aureus.We also propose the potential applications and prospects,and hope to provide an in-depth understanding on the antibacterial mechanism and a better guidance to the design and applications of this promising antibacterial material in the future.展开更多
Controlled synthesis of transition metal dichalcogenide (TMD) monolayers with unusual crystal phases has attracted increasing attention due to their promising applications in electrocatalysis.However,the facile and la...Controlled synthesis of transition metal dichalcogenide (TMD) monolayers with unusual crystal phases has attracted increasing attention due to their promising applications in electrocatalysis.However,the facile and large-scale preparation of TMD monolayers with high-concentration unusual crystal phase still remains a challenge.Herein,we report the synthesis of MoX2 (X =Se or S) monolayers with high-concentration semimetallic 1T'phase by using the 4H/face-centered cubic (fcc)-Au nanorod as template to form the 4H/fcc-Au@MoX2 nanocomposite.The concentrations of 1T'phase in the prepared MoSe2 and MoS2 monolayers are up to 86% and 81%,respectively.As a proof-of-concept application,the obtained Au@MoS2 nanocomposite is used for the electrocatalytic hydrogen evolution reaction (HER) in acid medium,exhibiting excellent performance with a low overpotential of 178 mV at the current density of 10 mNcm^2,a small Tafel slope of 43.3 mV/dec,and excellent HER stability.This work paves a way for direct synthesis of TMD monolayers with high-concentration of unusual crystal phase for the electrocatalytic application.展开更多
Over the past decade, ultrathin lanthanide oxides （Ln2O3, Ln = La to Lu） nanomaterials have been intensively studied in the fields of rare earth materials science. This unique class of nanomaterials has shown many u...Over the past decade, ultrathin lanthanide oxides （Ln2O3, Ln = La to Lu） nanomaterials have been intensively studied in the fields of rare earth materials science. This unique class of nanomaterials has shown many unprecedented properties （big surface area, high surface effect, physical and chemical activities） and is thus being explored for numerous promising applications. In this review, a brief introduction of ultrathin Ln2O3 nanomaterials was given and their unique advantages were highlighted. Then, the typical synthetic methodologies were summarized and compared （thermal decomposition, solvothermal, soft template, co-precipition and microwave etc.）. Due to the high surface effect, some promising applications of ultmthin Ln203 nanomaterials, such as drug delivery and catalysis of CO oxidation, were reviewed. Finally, on the basis of current achievements on ultrathin Ln203 nanomaterials, personal perspectives and challenges on future research directions were proposed.展开更多
Developing a reliable system to efficiently and safely deliver peptide drugs into tumor tissues still remains a great challenge since the instability of peptide drugs and low ability to traverse the cell membrane. Her...Developing a reliable system to efficiently and safely deliver peptide drugs into tumor tissues still remains a great challenge since the instability of peptide drugs and low ability to traverse the cell membrane. Herein, we constructed a multifunctional nanoplatform based on porous europium/gadolinium (Eu/Gd)-doped NaLa(MoO4)2 nanoparticles (NLM NPs) to deliver antitumor peptide of B-cell lymphoma/leukemia-2-like protein 11 (BIM) for cancer therapy. The porous NLM NPs exhibited inherent photoluminescent, magnetic and X-ray absorbable properties, which enable them for triple-modal bioimaging, including fluorescence, magnetic resonance imaging (MRI) and computed tomography (CT). This triple-modal bioimaging can contribute to monitoring NLM NPs biodistribution and guiding therapy in vitro and in vivo. Furthermore, the NLM NPs showed negligible cytotoxicity in vitro and tissue toxicity in vivo. Importantly, NLM NPs could load the antitumor peptide of BIM and efficiently improve the resistance of peptide drugs to proteolysis. The BIM peptide was efficiently delivered into the tumor cells by NLM NPs, which can inhibit the growth and promote the apoptosis of cancer cells in vitro, significantly inhibit the tumor growth in vivo. Notably, NLM-BIM theranostic nanoplatform exhibits low systemic toxicity and fewer side effects in vivo. The NLM NPs can serve as a promising multifunctional peptide delivery nanoplatform for multi-modal bioimaging and cancer therapy.展开更多
Direct ethanol fuel cells (DEFCs) have drawn attention for their simplicity, rapid start-up, high power density and environmental friendliness. Despite these advantages, the widespread application of DEFCs faces chall...Direct ethanol fuel cells (DEFCs) have drawn attention for their simplicity, rapid start-up, high power density and environmental friendliness. Despite these advantages, the widespread application of DEFCs faces challenges, primarily due to the inadequate performance of anode and cathode catalysts. Pd-based materials have shown exceptional catalytic activity for both the ethanol oxidation reaction (EOR) and the oxygen reduction reaction (ORR). Alloying noble metals with rare earth elements has emerged as an effective strategy to further enhance the catalytic activity by modulating the electronic structure. In this study, we synthesized a series of palladium-rare earth (Pd3RE) alloys supported on carbon to serve as bifunctional catalysts that efficiently promote both ORR and EOR. Compared to Pd/C, the Pd3Tb/C catalyst exhibits 3.1-fold and 1.8-fold enhancement in activity for ORR and EOR, respectively. The charge transfer in the Pd3Tb/C results in an electron-rich Pd component, thereby weakening the binding energy with oxygen species and facilitating the two reactions.展开更多
Improving the accuracy of transformer dissolved gas analysis is always an important demand for power companies.However,the requirement for large numbers of fault samples becomes an obstacle to this demand.This article...Improving the accuracy of transformer dissolved gas analysis is always an important demand for power companies.However,the requirement for large numbers of fault samples becomes an obstacle to this demand.This article creatively uses a large number of health data,which is much easier to obtain by power companies,to improve diagnosis accuracy.Comprehensive investigations from the view of both data set and methodology to deal with this problem are presented.A data set consists of 9595 health samples and 993 fault samples is used for analysis.The characteristics of the data set and the influence of the health data on diagnostic accuracy are discussed.The performance of many state‐of‐art algorithms that handle the imbalanced prob-lem is evaluated.Meanwhile,an efficient fault diagnosis algorithm named self‐paced ensemble(SPE)is presented.In SPE,classification hardness is proposed to include the data characteristic in the classification.This method can guarantee the diversity of the data set and keep high performance.According to the experiment results,the superior of SPE is confirmed and also proves that involving more health samples can improve transformer diagnosis when fault data are limited.展开更多
基金supported by National Natural Science Foundation of China(No.52507193).
文摘Transient simulation are more economical and adaptable means of studying lightning overvoltage for overhead distribution line system compared to experiments.A hybrid multi-transmission-line(MTL)-partial element equivalent circuit(PEEC)method proposed for lightning-induced electromagnetic pulse(LEMP)simulation is verified using the rocket-triggered experimental results under a more complex line configuration for the first time.This method can improve computational efficiency while ensuring calculation accuracy.The agreement between experimental and simulation results further validates the adaptability and accuracy of the proposed method,which is adopted to calculate the LEMP on the extended double-circuit parallel unequal length line.The effects of various factors,such as the strike-point location,the amplitude and waveform of the lightning current,the line shape and length on the amplitude of overvoltage and pole flashover along the line are discussed.For double-circuit distribution lines,when lightning strikes the ground in front of centre of circuit I,the three-phase voltage waveforms are similar,all of which are negative or bipolar oscillation waves.The closer the lightning strike point is to the line,the greater the amplitude of the lightning current,and the voltage waveform develops towards a bipolar waveform,but the main peak remains negative.As the amplitude of lightning current increases,the maximum lightning-induced voltage amplitude along the line increases.The LEMP caused by the subsequent return-stroke current is always greater than that caused by the first returnstroke current.When the grounding resistance increases,the maximum voltage peak amplitude along the line remains unchanged.
基金The National Key Research and Development Program of China under contact No.2021YFF0501304the Natural Science Foundation of Xiamen,China under contact No.3502Z20227244the Scientific Research Foundation of the Third Institute of Oceanography,MNR under contact Nos 2019021 and 2022009.
文摘Low iron content is a peculiar feature of marine ecosystems,where microbes have to produce iron-chelating molecules such as siderophores to survive.Very little is known about siderophore-producing bacteria in the oceans.In this study,we screened 1546 strains from marine seawater and sediments,which were deposited in the Marine Culture Collection of China(MCCC),and further analyzed the diversity of positive strains and their potential genes related to iron acquisition.Of the 1546 isolates,856 strains(55.37%)showed positive siderophore-producing activity on the Chrome Azurol Sulfonate(CAS)plates.Among these,isolates from seawater environments had a higher positive proportion(535).Some genera showed a higher proportion(>70%)of positive siderophore producers,such as Alteromonas(89/112),Marinobacter(78/109),Vibrio(21/27),Shewanella(7/8)in the Gammaproteobacteria,Sulfitobacter(17/21),Martelella(5/6)in the Alphaproteobacteria,and Joostella(6/7)in the phylum Bacteroidetes.Siderophore biosynthesis genes,including those for vanchrobactin,vibrioferrin,petrobactin,and aerobactin,as well as transport and iron storage proteins,were also identified in the positive bacterial genomes.The study revealed that a variety of bacterial strains demonstrate the production of siderophores,which could significantly contribute to the iron cycle within marine ecosystems,encompassing both seawater and marine sediments.
基金Project supported by the National Key R&D Program of China(2017YFA0208000)the National Natural Science Foundation of China(21971117,21522106)111 Project(B18030)from China。
文摘Solid lithium-ion-conducting material is the key component in the fabrication of next-gene ration all solid state lithium ion batteries(LIBs)which would exhibit superior safety and performance compared with the currently widely used ones that resort to essentially inflammable and volatile organic solvents.To date,great efforts have been made in developing solid conductors with high lithium ion conductivity,such as polymers and inorganic materials.Rare earths play a very important role in this area and have attracted extensive interest since the recent decades for their unique properties in the realm of solidstate inorganic lithium-ion-conducting electrolyte materials.In this introduction,we focus on the role of rare earths in solid conductors for lithium ion,especially in a few most studied systems such as perovskites,garnets,silicates,borohydride and the recently reported halides in which rare earths act as a key framing component.Besides,the effect of rare earths as dopants is also discussed in some recently studied systems.Valence,coordination,and size are the most important factors that influence the crystal structure and property of these lithium ion conductors.The aim of this review is to highlight the great potentials of these unique elements of rare earths,and to help improve the performance of existing materials and explore new applications in the development of new LIBs with high performances.
基金the National Natural Science Foundation of China(22371131)the 111 Project from China(B18030)+5 种基金the Beijing-Tianjin-Hebei Collaborative Innovation Project(19YFSLQY00030)the Outstanding Youth Project of Tianjin Natural Science Foundation(20JCJQJC00130)the Key Project of Tianjin Natural Science Foundation(20JCZDJC00650)the opening fund of Key Laboratory of Rare Earths,Chinese Academy of Sciencesthe Functional Research Funds for the Central Universities,Nankai University(63186005)Tianjin Key Lab for Rare Earth Materials and Applications(ZB19500202).
文摘The construction of rare earth(RE)alloy catalysts offers a route to harness the unique electronic structure of RE.Within the alloy,RE can fine-tune the electronic configuration of the active element,such as rhodium(Rh),via the ligand effect,optimizing the electrochemical reaction pathway.However,the challenging negative reduction potential of RE has impeded the progress in developing RE alloys,particularly nanoalloy catalysts.In this study,Rh_(3)Sc/C and Rh_(3)Y/C nanoalloys were synthesized using a sodium vapor reduction strategy for application as hydrogen evolution reaction(HER)catalysts.Elec-trochemical tests reveal that Rh-RE alloy catalysts exhibit significantly improved electrocatalytic activity in 1 mol/L KOH.Notably,Rh_(3)Y/C demonstrates exceptional HER performance,achieving a low over-potential of only 31 mV at 10 mA/cm^(2),surpassing the 50 mV observed for Rh/C.Furthermore,the current density of Rh_(3)Y/C at an 80 mV overpotential is 3.9 times that of Rh/C.This study sheds light on the remarkable catalytic potential of Rh-RE alloys,paving the way for the future expansion of RE nanoalloy systems.
文摘Applying a stimulating current to acupoints through acupuncture needles–known as electroacupuncture–has the potential to produce analgesic effects in human subjects and experimental animals. When acupuncture was applied in a rat model, adenosine 5-triphosphate disodium in the extracellular space was broken down into adenosine, which in turn inhibited pain transmission by means of an adenosine A1 receptor-dependent process. Direct injection of an adenosine A1 receptor agonist enhanced the analgesic effect of acupuncture. The analgesic effect of acupuncture appears to be mediated by activation of A1 receptors located on ascending nerves. In neuropathic pain, there is upregulation of P2X purinoceptor 3 （P2X3） receptor expression in dorsal root ganglion neurons. Conversely, the onset of mechanical hyperalgesia was diminished and established hyperalgesia was significantly reversed when P2X3 receptor expression was downregulated. The pathways upon which electroacupuncture appear to act are interwoven with pain pathways, and electroacupuncture stimuli converge with impulses originating from painful areas. Electroacupuncture may act via purinergic A1 and P2X3 receptors simultaneously to induce an analgesic effect on neuropathic pain.
基金Project supported by the National Natural Science Foundation of China(21522106.21971117)111 Project(B18030)from China+2 种基金the Open Fund of the State Key Laboratory of Rare Earth Resource Utilization(RERU2019001)the Functional Research Fund for the Central Universities,Nankai University(ZB19500202)Beijing-Tianjin-Hebei Collaborative Innovation Project(63201058).
文摘IrOx-based catalysts are considered the most promising candidates for oxygen evolution reaction(OER)due to their high efficiency.However,improving their intrinsic catalytic activity is essential for practical application.In this work,CeO_(2)with three different morphologies(rod,cube,octahedron)and supported IrOx nanoparticles were fabricated,and they display morphology-dependent OER activity.The IrOx/CeO_(2)-rod shows the highest activity;the catalysts have a catalytic activity sequence of rod>cube>octahedron.A plausible mechanism was proposed:the CeO_(2)support with different morphologies modulates the electronic structure of IrOx by the synergistic interaction promoted by oxygen vacancies between the active component and the support,thereby altering the catalytic activity of the IrOx/CeO_(2)catalyst.
基金Project supported by the National Natural Science Foundation of China(52003124,21971117)China Postdoctoral Science Foundation(2020M680862)+10 种基金the Fundamental Research Funds for the Central UniversitiesNankai University(63211029,63186005,63211042)Tianjin Key Lab for Rare Earth Materials and Applications(ZB 19500202)the Open Funds(RERU2019001)of the State Key Laboratory of Rare Earth Resource Utilizationthe National Key R&D Program of China(2017YFA0208000)the 111 Project(B18030)from ChinaBeijing-Tianjin-Hebei Collaborative Innovation Project(19YFSLQY00030)the Outstanding Youth Project of Tianjin Natural Science Foundation(20JCJQJC00130)the Key Project of Tianjin Natural Science Foundation(20JCZDJC00650)the Basic Scientific Research Business Expenses of the Central UniversityOpen Project of Key Laboratory for Magnetism and Magnetic Materials of the Ministry of Education,Lanzhou University(LZUMMM2021009)。
文摘For wound healing,wound infection caused by bacteria is one of the important reasons that delay wound healing process.Therefore,it is very meaningful to develop a multifunctional wound dressing with antibacterial capability to accelerate wound healing.Sodium alginate(SA)and carboxymethyl chitosan(CMCS)are the most commonly used compositions in wound dressing,but their poor stability inhibits the further applications.Introducing CMCS and using cerium ions(Ce^(3+))to crosslink CMCS and SA to form SA-CMCS hybrid spheres by electrostatic spray method,can not only improve the stability of SA hydrogels,but also endow the spheres with excelle nt antibacterial properties due to the characteristics of Ce^(3+).The gradual release of Ce^(3+)from the SA-CMCS spheres can effectively inhibit the growth of Staphylococcus aureus(S.aureus)and Escherichia coli(E.coli).Combining the wound healing promotion ability of SA and CMCS,this kind of wound dressing can not only avoid wound infection caused by bacteria effectively,but also accelerate wound healing,thus it is an easily prepared material with potential applications in skin defect repair.
基金We gratefully acknowledge the support from the National Key R&D Program of China(No.2021YFA1501101)the National Natural Science Foundation of China(No.21971117)+11 种基金the National Natural Science Foundation of China/Research Grant Council of Hong Kong Joint Research Scheme(No.N_PolyU502/21)Functional Research Funds for the Central Universities,Nankai University(No.63186005)Tianjin Key Lab for Rare Earth Materials and Applications(No.ZB19500202)111 Project(No.B18030)from Chinathe Outstanding Youth Project of Tianjin Natural Science Foundation(No.20JCJQJC00130)the funding for Projects of Strategic Importance of The Hong Kong Polytechnic University(Project Code:1-ZE2V)Shenzhen Fundamental Research Scheme-General Program(No.JCYJ20220531090807017)the Key Project of Tianjin Natural Science Foundation(No.20JCZDJC00650)the National Postdoctoral Program for Innovative Talents(No.BX20220157)Open Foundation of State Key Laboratory of Featured Metal Materials and Life-cycle Safety for Composite Structures(No.2022GXYSOF07)Departmental General Research Fund(Project Code:ZVUL)from Department of Applied Biology and Chemical Technology of Hong Kong Polytechnic UniversityHaihe Laboratory of Sustainable Chemical Transformations.
文摘Currently,single-atom combo catalysts(SACCs)for carbon dioxide reduction reaction(CO_(2)RR)to the formation of HCOOH are still very limited,especially the lanthanide-based SACCs.In this work,the novel SACCs with atomically dispersed In and Ce active sites were successfully prepared on the nitrogen-doped carbon matrix(InCe/CN).Both aberration-corrected high-angle annular dark-field scanning transmission electron microscopy(AC-HAADF-STEM)images and the extended X-ray absorption fine structure(EXAFS)spectra proved the well-isolated In and Ce atoms.The as-prepared InCe/CN shows a high Faradaic efficiency(FE)(77%)and current density of HCOOH formation(j_(HCOOH))at-1.35 V vs.reversible hydrogen electrode(RHE),much higher than the single atom catalysts.Theoretical calculations have indicated that the introduced Ce single atom sites not only significantly promote electron transfer but also optimize the In-5p orbitals towards higher selectivity towards the HCOOH formation.This work innovatively extends the design of SACCs towards the main group and Ln metals for more applications.
基金This work was financially supported by the National Natural Science Foundation of China （Nos. 21105079 and 21405119）, the Fundamental Research Funds for the Central Universities of China （Nos. 0109-1191320016 and cxtd2015003）, the Scientific Research Foundation for the Returned Overseas Chinese Scholars by the State Education Ministry of China, and the Interna- tional Science and Technology Cooperation and Exchange Program of Shaanxi Province of China （No. 2016KW-064）. Yaping Du gratefully acknowledgesthe financial support from the start-up funding from Xi＇an Jiaotong University, the Fundamental Research Funds for the Central Universities of China （No. 2015qngz12）, and the the National Natural Science Foundation of China （Nos. 21522106 and 21371140）.
文摘Developments of nanostructured transition metal dichalcogenides （TMDs） materials as novel electrocatalyst candidates for oxygen reduction reaction （ORR） is a new strategy to promote the developments of non-precious metal ORR catalysts. In this work, a three-dimensional （3D） hybrid of rosebud-like MoSe2 nanostructures supported on reduced graphene oxide （rGO） nanosheets was successfully synthesized through a facile hydrothermal strategy. The prepared MoSe2@rGO hybrid nanostructure showed enhanced electrocatalytic activity for the ORR in alkaline medium compared to that of the pure MoSe2, rGO, and their simple physical mixture, which could benefit from the excellent oxygen adsorption ability of the abundantly exposed active edge sites of the ultrathin MoSe2 layers, the conductivity and aggregation-limiting effect of the rGO platform, as well as the unique 3D rosebud-like architecture of the hybrid material. The electrocatalytic activity of the MoSe2@rGO hybrid towards ORR was comparable to that of com- inertial Pt/C catalysts. And the promoted reaction was revealed to involve a nearly four-electron-dominated ORR process by analysis of the obtained Koutecky- Levich plots. The scanning electrochemical microscopy （SECM） technique, with the advantages of investigating of the local catalytic activity of samples with high spatial resolution and simultaneously evaluating activities of different catalysts in a single experiment, was further applied to investigate the local ORR electrocatalytic activity of MoSe2@rGO and compare it with those of other catalyst samples through applying different sample potentials. The excellent stability and methanol tolerance of the 3D nanostructured MoSe2@rGO hybrid against methanol further prove the 3D nanostructured MoSe2@rGO hybrid as a promising ORR electrocatalyst in alkaline solution for potential applications in fuel cells and metal-air batteries.
基金This work was supported by the National Key R&D Program of China(No.2021YFA1501101)the Natural Science Foundation of China(No.21971117)+11 种基金Functional Research Funds for the Central Universities,Nankai University(No.63186005)Tianjin Key Lab for Rare Earth Materials and Applications(No.ZB19500202)the National Natural Science Foundation of China/Research Grant Council Joint Research Scheme(No.N_PolyU502/21)111 Project(No.B18030)from ChinaOutstanding Youth Project of Tianjin Natural Science Foundation(No.20JCJQJC00130)Key Project of Tianjin Natural Science Foundation(No.20JCZDJC00650)the Projects of Strategic Importance of The Hong Kong Polytechnic University(No.1-ZE2V)Shenzhen Fundamental Research Scheme-General Program(No.JCYJ20220531090807017)National Postdoctoral Program for Innovative Talents(No.BX20220157)Open Foundation of State Key Laboratory of Featured Metal Materials and Life-cycle Safety for Composite Structures(No.2022GXYSOF07)Haihe Laboratory of Sustainable Chemical Transformations.B.L.H.also thanks the support from Research Centre for Carbon-Strategic Catalysis(RCCSC),Research Institute for Smart Energy(RISE)Research Institute for Intelligent Wearable Systems(RI-IWEAR)of the Hong Kong Polytechnic University.
文摘Rare-earth(RE)halide solid electrolytes(HSEs)have been an emerging research area due to their good electrochemical and mechanical properties for all-solid-state lithium batteries(ASSBs).However,only very limited types of HSEs have been reported with high performance.In this work,tens of grams of RE-HSE Li_(3)TbBr_(6)(LTbB)was synthesized by a vacuum evaporationassisted method.The as-prepared LTbB displays a high ionic conductivity of 1.7 mS·cm^(-1),a wide electrochemical window,and good formability.Accordingly,the assembled solid lithium-tellurium(Li-Te)battery based on the LTbB HSE exhibits excellent cycling stability up to 600 cycles,which is superior to most previous reports.The processes and the chemicals during the discharge/charge of Li-Te batteries have been studied by various in situ and ex situ characterizations.Theoretical calculations have demonstrated the dominant conductivity contributions of the direct[octahedral]-[octahedral]([Oct]-[Oct])pathway for Li ion migrations in the electrolyte.The Tb sites guarantee efficient electron transfer while the Li 2s orbitals are not affected during migration,leading to a low activation barrier.Therefore,this successful fabrication and application of LTbB have offered a highly competitive solution for solid electrolytes in ASSBs,indicating the great potential of RE-based HSEs in energy devices.
基金the support from the National Key R&D Program of China(No.2021YFA1501101)the National Natural Science Foundation of China(No.21971117)+12 种基金the National Natural Science Foundation of China/Research Grant Council of Hong Kong Joint Research Scheme(No.N_PolyU502/21)the National Natural Science Foundation of China/Research Grants Council(RGC)of Hong Kong Collaborative Research Scheme(No.CRS_PolyU504/22)the Functional Research Funds for the Central Nankai University(No.63186005)the Tianjin Key Lab for Rare Earth Materials and Applications(No.ZB19500202)the Open Funds(No.RERU2019001)the State Key Laboratory of Rare Earth Resource Utilization,the 111 Project(No.B18030)from Chinathe Beijing-Tianjin-Hebei Collaborative Innovation Project(No.19YFSLQY00030)the Outstanding Youth Project of Tianjin 21 Natural Science Foundation(No.20JCJQJC00130)the Key Project of Tianjin Natural Science Foundation(No.20JCZDJC00650)the funding for Projects of Strategic Importance of The Hong Kong Polytechnic University(Project Code:1-ZE2V)the Shenzhen Fundamental Research Scheme-General Program(No.JCYJ20220531090807017)the Natural Science Foundation of Guangdong Province(No.2023A1515012219)the Departmental General Research Fund(Project Code:ZVUL)from The Hong Kong Polytechnic University.
文摘Currently,dual atomic catalysts(DACs)with neighboring active sites for oxygen reduction reaction(ORR)still meet lots of challenges in the synthesis,especially the construction of atomic pairs of elements from different blocks of the periodic table.Herein,a“rare earth(Ce)-metalloid(Se)”non-bonding heteronuclear diatomic electrocatalyst has been constructed for ORR by rational coordination and carbon support defect engineering.Encouraging,the optimized Ce-Se diatomic catalysts(Ce-Se DAs/NC)displayed a half-wave potential of 0.886 V vs.reversible hydrogen electrode(RHE)and excellent stability,which surpass those of separate Ce or Se single atoms and most single/dual atomic catalysts ever reported.In addition,a primary zinc-air battery constructed using Ce-Se DAs/NC delivers a higher peak power density(209.2 mW·cm^(−2))and specific capacity(786.4 mAh·gZn^(−1))than state-of-the-art noble metal catalysts Pt/C.Theoretical calculations reveal that the Ce-Se DAs/NC has improved the electroactivity of the Ce-N_(4)region due to the electron transfer towards the nearby Se specific activity(SA)sites.Meanwhile,the more electron-rich Se sites promote the adsorptions of key intermediates,which results in the optimal performances of ORR on Ce-Se DAs/NC.This work provides new perspectives on electronic structure modulations via non-bonded long-range coordination micro-environment engineering in DACs for efficient electrocatalysis.
基金supported by the National Natural Science Foundation of China(no.21971117)Functional Research Funds for the Central Universities,Nankai University(no.63186005)+6 种基金Tianjin Key Lab for Rare Earth Materials and Applications(no.ZB19500202)the Open Funds(no.RERU2019001)of the State Key Laboratory of Rare Earth Resource Utilization,111 Project(no.B18030)from China,Beijing–Tianjin–Hebei Collaborative Innovation Project(no.19YFSLQY00030)the Outstanding Youth Project of TianjinNatural Science Foundation(no.20JCJQJC00130)the Key Project of Tianjin Natural Science Foundation(no.20JCZDJC00650)fundings from Basic Scientific Research in Central Universities(grant no.G2020KY0535)the Foundation of Shaanxi Province Natural Science Basic Research Program(grant nos.2021JQ-095 and 2020JQ-146)Postdoctoral Science Foundation of China(nos.2019TQ0265 and 2019M663809).
文摘Heterophase nanomaterials composed of multiple phases have attracted increasing attention due to their enhanced performance in electrocatalytic field.Nevertheless,constructing two-dimensional(2D)crystalline/amorphous heterophase nanostructures with the samechemical composition remains a great challenge.Herein,we report the preparation of a 2D crystalline/amorphous heterophase of MoS2 nanosheets with the same elemental components via a facile solvothermal method.
基金financial support provided by the National Natural Science Foundation of China(Nos.52363014 and 22405179)the Science and Technology Project of Guangxi(GK AB23026136)the Open Fund Funding of Key Laboratory of New Processing Technology for Nonferrous Metal&Materials,Ministry of Education/Guangxi Key Laboratory of Optical and Electronic Materials and Devics(22AA-7).
文摘Metabolism,transpiration,and invasion of pathogens during the storage and transportation of fruits can lead to significant waste and even food safety issues.Therefore,real-time,rapid,and accurate non-destructive monitoring of physiological information during the storage of fruits and vegetables to assess fruit freshness is crucial.Herein,we engineered a degradable and multifunctional humidity sensing film for monitoring fruit freshness.The film is fabricated through the co-assembly of bagasse cellulose nanocrystals(CNC),okra polysaccharides(OPs),silver nanowires(Ag NWs),and phytic acid(PA),utilizing dynamic hydrogen and phosphate bonds.This innovative design endows the CNC/OPs/PA/Ag NWs(COPA)composite film with outstanding mechanical properties,water resistance,low water vapor permeability,antibacterial,degradability,and moisture-sensing ability.Notably,the proposed COPA humidity sensor exhibits high linearity(R^(2)=0.994),ultralow hysteresis(1.24%),and 32 days of operational stability across a 35%–98%relative humidity(RH)range,enabling precise freshness monitoring during fruit storage.Significantly,the COPA film prolonged the shelf-life of packaged fruit when compared to conventional PE film packaging.This research establishes a foundational framework for next-generation smart sensors in food quality management and biomedical monitoring applications.
基金support from the National Funds for Excellent Young Scientists of China (21522106)the National Key R&D Program of China (2017YFA0208000)the 111 Project (B18030) from China
文摘Nanomaterials have been applied as antibacterial agents by virtue of their unique functioning mechanism different from that of conventional antibiotics.Cerium oxide nanoparticles(CeO2 NPs)are important antibacterial agents due to their relatively low toxicity to normal cells and their distinct antibacterial mechanism based on the reversible conversion between two valence states of Ce(III)/Ce(IV).Some studies have been conducted to explore their antibacterial activities;however,systematic research reviews on the related mechanisms and influencing factors are still quite rare.In this review,we discuss the plausible mechanisms of the antibacterial activity of CeO2 NPs,analyze different influencing factors,and summarize various research reports on antibacterial effects on E.coli and S.aureus.We also propose the potential applications and prospects,and hope to provide an in-depth understanding on the antibacterial mechanism and a better guidance to the design and applications of this promising antibacterial material in the future.
文摘Controlled synthesis of transition metal dichalcogenide (TMD) monolayers with unusual crystal phases has attracted increasing attention due to their promising applications in electrocatalysis.However,the facile and large-scale preparation of TMD monolayers with high-concentration unusual crystal phase still remains a challenge.Herein,we report the synthesis of MoX2 (X =Se or S) monolayers with high-concentration semimetallic 1T'phase by using the 4H/face-centered cubic (fcc)-Au nanorod as template to form the 4H/fcc-Au@MoX2 nanocomposite.The concentrations of 1T'phase in the prepared MoSe2 and MoS2 monolayers are up to 86% and 81%,respectively.As a proof-of-concept application,the obtained Au@MoS2 nanocomposite is used for the electrocatalytic hydrogen evolution reaction (HER) in acid medium,exhibiting excellent performance with a low overpotential of 178 mV at the current density of 10 mNcm^2,a small Tafel slope of 43.3 mV/dec,and excellent HER stability.This work paves a way for direct synthesis of TMD monolayers with high-concentration of unusual crystal phase for the electrocatalytic application.
基金supported by the Start-up Funding from Xi’an Jiaotong Universitythe Fundamental Research Funds for the Central Universities (2015qngz12)+1 种基金the National Natural Science Foundation of China (21371140)the China National Funds for Excellent Young Scientists (21522106)
文摘Over the past decade, ultrathin lanthanide oxides （Ln2O3, Ln = La to Lu） nanomaterials have been intensively studied in the fields of rare earth materials science. This unique class of nanomaterials has shown many unprecedented properties （big surface area, high surface effect, physical and chemical activities） and is thus being explored for numerous promising applications. In this review, a brief introduction of ultrathin Ln2O3 nanomaterials was given and their unique advantages were highlighted. Then, the typical synthetic methodologies were summarized and compared （thermal decomposition, solvothermal, soft template, co-precipition and microwave etc.）. Due to the high surface effect, some promising applications of ultmthin Ln203 nanomaterials, such as drug delivery and catalysis of CO oxidation, were reviewed. Finally, on the basis of current achievements on ultrathin Ln203 nanomaterials, personal perspectives and challenges on future research directions were proposed.
基金National Key R&D Program of China (No. 2017YFA0208000)the China National Funds for Excellent Young Scientists (No. 21522106)+3 种基金Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine ResearchCollege of Stomatology, Xian Jiaotong University (No. 2018LHM-KFKT004)National Natural Science Foundation of China (Nos. 51502237, 51872224, and U1501245)We also appreciate Dr. Dong Su from the Center for Functional Nanomaterials at Brookhaven National Laboratory for his kind help in Electron Microscopy (EM) work.
文摘Developing a reliable system to efficiently and safely deliver peptide drugs into tumor tissues still remains a great challenge since the instability of peptide drugs and low ability to traverse the cell membrane. Herein, we constructed a multifunctional nanoplatform based on porous europium/gadolinium (Eu/Gd)-doped NaLa(MoO4)2 nanoparticles (NLM NPs) to deliver antitumor peptide of B-cell lymphoma/leukemia-2-like protein 11 (BIM) for cancer therapy. The porous NLM NPs exhibited inherent photoluminescent, magnetic and X-ray absorbable properties, which enable them for triple-modal bioimaging, including fluorescence, magnetic resonance imaging (MRI) and computed tomography (CT). This triple-modal bioimaging can contribute to monitoring NLM NPs biodistribution and guiding therapy in vitro and in vivo. Furthermore, the NLM NPs showed negligible cytotoxicity in vitro and tissue toxicity in vivo. Importantly, NLM NPs could load the antitumor peptide of BIM and efficiently improve the resistance of peptide drugs to proteolysis. The BIM peptide was efficiently delivered into the tumor cells by NLM NPs, which can inhibit the growth and promote the apoptosis of cancer cells in vitro, significantly inhibit the tumor growth in vivo. Notably, NLM-BIM theranostic nanoplatform exhibits low systemic toxicity and fewer side effects in vivo. The NLM NPs can serve as a promising multifunctional peptide delivery nanoplatform for multi-modal bioimaging and cancer therapy.
基金supported by National Key Research and Development Program of China(No.2021YFA1601004).
文摘Direct ethanol fuel cells (DEFCs) have drawn attention for their simplicity, rapid start-up, high power density and environmental friendliness. Despite these advantages, the widespread application of DEFCs faces challenges, primarily due to the inadequate performance of anode and cathode catalysts. Pd-based materials have shown exceptional catalytic activity for both the ethanol oxidation reaction (EOR) and the oxygen reduction reaction (ORR). Alloying noble metals with rare earth elements has emerged as an effective strategy to further enhance the catalytic activity by modulating the electronic structure. In this study, we synthesized a series of palladium-rare earth (Pd3RE) alloys supported on carbon to serve as bifunctional catalysts that efficiently promote both ORR and EOR. Compared to Pd/C, the Pd3Tb/C catalyst exhibits 3.1-fold and 1.8-fold enhancement in activity for ORR and EOR, respectively. The charge transfer in the Pd3Tb/C results in an electron-rich Pd component, thereby weakening the binding energy with oxygen species and facilitating the two reactions.
基金Science and Technology Project of State Grid Corporation of China,Grant/Award Number:5500‐202019090A‐0‐0‐00。
文摘Improving the accuracy of transformer dissolved gas analysis is always an important demand for power companies.However,the requirement for large numbers of fault samples becomes an obstacle to this demand.This article creatively uses a large number of health data,which is much easier to obtain by power companies,to improve diagnosis accuracy.Comprehensive investigations from the view of both data set and methodology to deal with this problem are presented.A data set consists of 9595 health samples and 993 fault samples is used for analysis.The characteristics of the data set and the influence of the health data on diagnostic accuracy are discussed.The performance of many state‐of‐art algorithms that handle the imbalanced prob-lem is evaluated.Meanwhile,an efficient fault diagnosis algorithm named self‐paced ensemble(SPE)is presented.In SPE,classification hardness is proposed to include the data characteristic in the classification.This method can guarantee the diversity of the data set and keep high performance.According to the experiment results,the superior of SPE is confirmed and also proves that involving more health samples can improve transformer diagnosis when fault data are limited.
